Altered cerebellar connectivity in autism and cerebellar-mediated rescue of autism-related behaviors in mice
Nature Neuroscience, Published online: 30 October 2017; doi:10.1038/s41593-017-0004-1
Cerebellar right Crus I (RCrusI) has been implicated in autism spectrum disorder (ASD). RCrusI modulation altered RCrusI–inferior parietal lobule connectivity, and this connectivity was atypical in children with ASD and in a TscI mouse model of ASD. Inhibition of RCrusI in mice led to autism-related behaviors, and RCrusI activation rescued social impairments in TscI mice.
from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2iKAYbj
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