Source:Gene, Volume 662
Author(s): Leonardo Rossi, Lucia Cassella, Paola Iacopetti, Claudio Ghezzani, Luigi Tana, Gregory Gimenez, Eric Ghigo, Alessandra Salvetti
Despite the significant advances in the comprehension of stem cell control network, the nature of extrinsic signals regulating their dynamic remains to be understood. In this paper, we take advantage of the stem cell repopulation process that follows low-dose X-ray treatment in planarians to identify genes, preferentially enriched in differentiated cells, whose expression is activated during the process. Genetic silencing of some of them impaired the stem cell repopulation, suggesting a tight extrinsic control of stem cell activity.
from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader https://ift.tt/2JAh5g3
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