Preschool and School-Age Irritability Predict Reward-Related Brain Function

Although chronic irritability in childhood is prevalent, impairing, and predictive of later maladjustment, its pathophysiology is largely unknown. Deficits in reward processing are hypothesized to play a role in irritability. The current study aimed to identify how the developmental timing of irritability during preschool and school-age relates to reward-related brain function during school-age.

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