Understanding the drivers of MHC restriction of T cell receptors

Understanding the drivers of MHC restriction of T cell receptors

Understanding the drivers of MHC restriction of T cell receptors, Published online: 10 April 2018; doi:10.1038/s41577-018-0007-5

Jamie Rossjohn and colleagues review the structural and functional data that provide insight into the MHC restriction of T cell receptors. They discuss the non-mutually exclusive contributions of intrinsic germline-encoded motifs and developmental selection to MHC restriction.

from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader https://ift.tt/2GNPPJ2