Racial differences in Atopic Dermatitis

Atopic dermatitis (AD), the most common chronic inflammatory skin disease,1 usually starts in early infancy, and can develop into a life-long therapeutic challenge, especially in its moderate-to-severe form.2 The etiology of this complex disease remains only partly understood, but it is most likely based on a complex interplay of genetic predisposition, skin barrier dysfunction, and environmental factors.3 AD is now understood to be an immune mediated disease with contributions of multiple inflammatory pathways, and particularly Type 2-associated inflammation.

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