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AbstractAcute cutaneous wounds remain prevalent and demanding in dermatology. Although stem cell‐based treatment has therapeutic benefits in wound repair, the clinical application is still limited.1 Exosomes have effect on promoting tissue regeneration and could be an alternative of stem cells like ASC‐derived exosomes (ASC‐Exos).2‐6 The retention of exosome in targeted area needs to be enhanced, and hyaluronic acid (HA) may serve as exosome immobilizer and wound dressing.7 In this pilot...
AbstractPrimary cutaneous gamma/delta T‐cell lymphoma (pcGDTCL) is a rare, aggressive T‐cell lymphoma that presents with ulcerated nodules, extranodal dissemination, constitutional symptoms, and often, hemophagocytic lymphohistiocytosis (HLH).1 pcGDTCL is so named given the gamma/delta phenotype of the T‐cell receptor (TCR).This article is protected by copyright. All rights reserved.
AbstractFollowing our report of full thickness grafts for repair of ala defects1, we present our experience with conchal bowl donor skin, for reconstruction of partial‐thickness defects of the ala.Analysis of electronic medical records (April 2007 to January 2017) identified all cases. Defect dimension, revisionary procedures, infections and necrosis were recorded. Patients were reviewed 5 days, 6 weeks and 1 year postoperatively. Subjective outcomes were assessed independently by two Consultant...
AbstractPyoderma gangrenosum (PG) is an uncommon inflammatory skin disorder, often associated with arthritis, inflammatory bowel disease, and/or hematologic malignancies [1]. A classic feature of PG is the development or worsening of lesions at areas that experience trauma, also known as pathergy. Autologous skin grafting may be challenging in these patients due to the potential for pathergy at the donor site. We are presenting a case of a patient diagnosed with PG, whereby we utilized a...
AbstractBackgroundSunscreen use can prevent skin cancer, but there are concerns that it may increase the risk of vitamin D deficiency.ObjectivesWe aimed to review the literature to investigate associations between sunscreen use and vitamin D3 or 25 hydroxy vitamin D (25(OH)D) concentration.MethodsWe systematically reviewed the literature following the MOOSE guidelines. We identified manuscripts published in English between 1970 and 21 November 2017. Eligible studies were experimental (using...
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Abstract Acne patients may have significant quality-of-life (QoL) impairment, therefore assessment of health-related QoL (HRQoL) in acne patients is recommended by several national and international guidelines as an integral part of acne management. The inclusion of QoL assessment in core outcome sets is now a popular idea. Several acne-specific QoL questionnaires are available but none cover all topics presented in other instruments. The impact of acne on different aspects of...
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AbstractMelanoma is one of the most serious form of skin cancer. Nowadays, ipilimumab is used for advanced melanoma refractory to first‐line anti‐programmed death 1 (PD‐1) antibodies. Thirty patients (male : female ratio, 18:12; median age, 60.5 years) sequentially treated with ipilimumab after anti‐PD‐1 antibody (nivolumab or pembrolizumab), while 58 (male : female ratio, 27:31; median age, 66.5 years) with anti‐PD‐1 antibody only. The kind of therapy and schedules were as follows: nivolumab,...
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