Resultados oncológicos de la laringectomía de rescate en pacientes con carcinomas escamosos de laringe Publication date: Available online 26 April 2019 Source: Acta Otorrinolaringológica Española Author(s): Xavier León, Victoria Montoro, Carlota Rovira, Eduard Neumann, Montserrat López, Jacinto García, Miquel Quer ResumenObjetivoAnalizar los resultados oncológicos conseguidos con una laringectomía total como cirugía de rescate en pacientes con carcinomas escamosos de la laringe. Material y métodosRevisión retrospectiva de una cohorte de 241 pacientes tratados con una laringectomía total tras una recidiva local de la enfermedad. El tratamiento inicial recibido por los pacientes fue de radioterapia (n = 201; 83,4%), quimiorradioterapia (n = 19; 7,9%), o una cirugía parcial (n = 21; 8,7%). ResultadosLa laringectomía total como cirugía de rescate consiguió el control local de la enfermedad en el 81,3% de las ocasiones, con una supervivencia específica a los 5 años del 65,3%. Las variables relacionadas con la supervivencia específica en un estudio univariante fueron la localización del tumor, la extensión local del tumor inicial y de la recidiva, los márgenes de resección, y el estatus patológico de los vaciamientos cervicales. De acuerdo con los resultados de un análisis multivariante, las variables que se relacionaron con la supervivencia fueron el estatus de los márgenes de resección, la presencia de una recidiva regional simultánea y la extensión local de la recidiva. ConclusionesLa supervivencia específica a los 5 años de los pacientes tratados con una laringectomía total de rescate fue del 65,3%. Las variables que se relacionaron con el control final de la enfermedad fueron el estatus de los márgenes de resección, la presencia de una recidiva regional simultánea y la extensión local de la recidiva. AbstractObjectiveTo analyse the oncological results of a salvage total laryngectomy in patients with a laryngeal carcinoma. Material and methodsRetrospective review of a cohort of 241 patients treated with a salvage laryngectomy after a local recurrence. The initial treatment received by these patients was radiotherapy (n = 201, 83.4%), chemoradiotherapy (n = 19, 7.9%), and partial surgery (n = 21, 8.7%), ResultsTotal laryngectomy as salvage treatment achieved local control of the disease in 81.3% of cases, with a 5-year specific survival of 65.3%. The variables related with specific survival in a univariate analysis were the location of the primary tumour, the local extension of the initial tumour and of the recurrence, the resection margins, and the pathological status of the neck dissections. According to the results of a multivariate analysis, the variables related to specific survival were the status of the resection margins, the presence of simultaneous regional recurrence, and the local extension of the recurrence. ConclusionThe 5-year specific survival of patients treated with a salvage laryngectomy was 65.3%. The variables related with the control of the disease were the status of the resection margins, the presence of simultaneous regional recurrence and the local extension of the recurrence. |
Paediatric nasal dermoids: Our experience Publication date: Available online 24 April 2019 Source: Acta Otorrinolaringológica Española Author(s): Ravi Meher, Avani Jain, Ishwar Singh, Nivea Singh, Raman Sharma AbstractObjectivesNasal dermoids are rare developmental anomalies seen in children. This study reports our experience in a developing country of the clinical and radiological findings as well as the management of nasal dermoids. MethodsA retrospective analysis was performed, from 2012 to 2017, for 10 patients admitted for the treatment of nasal dermoids at a tertiary care center. The clinical presentation, preoperative imaging (CT/MRI), surgical approach, intraoperative findings, complications and recurrence were reviewed. ResultsTen patients were included in this study, 6 males and 4 females, with an average age of 10.2 years at the time of presentation. Three patients presented with a mass located on the nasal dorsum, 1 had a nasoglabellar mass, 2 patients had a mass located on the nasal dorsum with visible sinus, and 4 patients presented with a sinus on the nasal dorsum, in which 1 patient had a tuft of hair. CT was performed in all the cases. It was not suggestive of intracranial extension in 9 patients, and was non-diagnostic in one patient. Both CT and MRI were performed on 2 patients, with no evidence of intracranial extension. Surgical and radiological findings were concordant in 8 patients (80%). ConclusionNasal dermoids require preoperative imaging and precise surgical planning to achieve complete removal. ResumenObjetivosLos dermoides nasales son anomalías del desarrollo poco frecuentes que se observan en niños. Este estudio informa de nuestra experiencia, en un país en desarrollo, de los hallazgos clínicos y radiológicos, así como el manejo de los dermoides nasales. MétodosSe realizó un análisis retrospectivo, desde 2012-2017, para 10 pacientes ingresados ??para el tratamiento de dermoide nasal en un instituto de nivel terciario. Se revisaron la presentación clínica, las imágenes preoperatorias (TC/RM), el abordaje quirúrgico, los hallazgos intraoperatorios, las complicaciones y la recurrencia. ResultadosSe incluyeron 10 pacientes en este estudio, 6 varones y 4 mujeres, con una edad promedio de 10,2 años en el momento de la presentación. Tres pacientes presentaban una masa localizada en el dorso nasal, uno tenía una masa nasoglabellar, 2 pacientes presentaban una masa localizada en el dorso nasal con seno visible y 4 pacientes presentaban un seno en el dorso nasal, de los cuales un paciente tenía un mechón de pelo. La TC se realizó en todos los casos. No sugirió una extensión intracraneal en 9 pacientes y no fue diagnóstico en un paciente. Tanto la TC como la RM se realizaron en 2 pacientes, sin evidencia de extensión intracraneal. Los hallazgos quirúrgicos y radiológicos fueron concordantes en 8 pacientes (80%). ConclusiónLos dermoides nasales requieren imágenes preoperatorias y una planificación quirúrgica precisa para lograr una extracción completa. |
Trismus and oral haematoma, a rare presentation of tetanus Publication date: Available online 20 April 2019 Source: Acta Otorrinolaringológica Española Author(s): Miguel Mayo-Yáñez, Liliana Invencio-Da Costa |
Chronic cough and pneumonitis secondary to cerebrospinal fluid leak: Resolution after repair Publication date: Available online 16 April 2019 Source: Acta Otorrinolaringológica Española Author(s): Daniel William Scholfield, Catherine Rennie, Hesham A. Saleh |
Carcinoma de paratiroides, una causa inusual de hiperparatiroidismo primario Publication date: Available online 15 April 2019 Source: Acta Otorrinolaringológica Española Author(s): Liliana Filipa Invêncio da Costa, Fabian Alzate Amaya, Jesús Herranz González Botas |
Músculo elevador de la clavícula Publication date: Available online 13 April 2019 Source: Acta Otorrinolaringológica Española Author(s): José Miguel Costa González, Rosa Delia Ramírez Ruíz, Anna Sumarroca Trouboul |
Riesgo de aparición de segundas neoplasias y neoplasias sucesivas en pacientes con un tumor índice de cabeza y cuello Publication date: Available online 12 April 2019 Source: Acta Otorrinolaringológica Española Author(s): Xavier León, Jacinto García, Montserrat López, Camilo Rodriguez, Alfons Gutierrez, Miquel Quer ResumenObjetivoAnalizar la incidencia de aparición de segundas neoplasias y neoplasias sucesivas en una cohorte de pacientes con un carcinoma escamoso de cabeza y cuello. Material y métodosEstudio retrospectivo realizado en 4.458 pacientes con un tumor índice localizado en cabeza y cuello diagnosticados durante el periodo 1985-2016. Se llevó a cabo una evaluación de la incidencia de aparición de segundas neoplasias y neoplasias sucesivas a lo largo de un periodo de 30 años. ResultadosDurante el seguimiento, un total de 1.203 pacientes (27,0%) contaron con la aparición de una segunda neoplasia, 242 (5,4%) con una tercera neoplasia, 58 (1,3%) con una cuarta y 8 (0,2%) con 5 o más neoplasias. La incidencia de aparición de segundas neoplasias fue del 3,5% anual, manteniéndose prácticamente constante a lo largo del periodo de seguimiento. Los pacientes que experimentaron la aparición de una segunda neoplasia contaron con un riesgo aumentado de presentar una tercera neoplasia, y los pacientes con una tercera neoplasia, con un riesgo aumentado de presentar una cuarta. Un 78% de las segundas, un 88% de las terceras y un 89,6% de las cuartas neoplasias aparecieron en localizaciones epidemiológicamente relacionadas con los consumos de tabaco y alcohol. ConclusionesTras el diagnóstico y tratamiento de un tumor índice de cabeza y cuello los pacientes cuentan con un riesgo de aparición de una segunda neoplasia del 3,5% anual, y este riesgo permanece constante a lo largo del periodo de seguimiento a largo plazo. AbstractObjectiveTo analyse the incidence of appearance of second and successive neoplasms in a cohort of head and neck squamous carcinoma patients. Material and methodsWe conducted a retrospective study with 4,458 patients with an index tumour located in the head and neck diagnosed during the 1985-2016 period. We evaluated the incidence of appearance of second neoplasms and successive neoplasms over a period of 30 years. ResultsDuring the follow-up, 1,203 patients (27.0%) had a second neoplasm, 242 patients (5.4%) a third neoplasm, 58 patients (1.3%) a fourth neoplasm, and 8 patients (0.2%) 5 or more successive neoplasms. The incidence of appearance of second neoplasms was 3.5% per year, remaining relatively constant throughout the follow-up period. The patients with a second neoplasm had a higher risk of appearance of a third neoplasm, and those with a third neoplasm had a higher risk of a fourth. Seventy-eight percent of the second neoplasms, 88% of the third neoplasms, and 89.6% of the fourth neoplasms appeared in locations epidemiologically related to tobacco and alcohol use. ConclusionsSecond neoplasms after a head and neck index tumour appeared at a constant rate of 3.5% per year throughout the entire follow-up period. |
Intoxicación por monóxido de carbono: una causa rara de hipoacusia neurosensorial reversible Publication date: Available online 7 March 2019 Source: Acta Otorrinolaringológica Española Author(s): Martin Marcano Acuña, Iván Doménech Máñez, Francisco Llopis Llopis, Manuel Salvador Marín |
Manejo del absceso de la glándula tiroides Publication date: March–April 2019 Source: Acta Otorrinolaringológica Española, Volume 70, Issue 2 Author(s): Javier García Callejo, Jaume Redondo Martínez, Miguel Civera, José Verdú Colomina, Verónica Pellicer Zoghbi, M. Paz Martínez Beneyto ResumenIntroducciónLa enfermedad supurativa de la glándula tiroides-absceso de tiroides o tiroiditis supurativa aguda– supone una infrecuente situación clínica. Presentamos nuestra experiencia en los casos asistidos durante 41 años. Materiales y métodosEstudio longitudinal retrospectivo anotando características epidemiológicas, conducta diagnóstico-terapéutica y resultado clínico, detectando 14 casos –9 varones y 5 mujeres, entre 19 y 68 años, con una media de edad de 40,6 ± 15,4 años– con 22 episodios. En 2 pacientes la condición se había reproducido hasta en 4 ocasiones. ResultadosSupusieron el 0,29% de todos los abscesos cervicales atendidos. La punción-aspiración fue efectuada en 13 de ellos para su tratamiento e identificación del agente causal. Los agentes más habitualmente implicados fueron Mycobacterium tuberculosis y Staphylococcus aureus. Se realizó un estudio de imagen mediante ecografía en 9 casos y de tomografía computarizada en 7. En 10 pacientes el tratamiento definitivo fue quirúrgico, efectuándose drenaje del absceso en 7 de ellos, tiroidectomía total en 4 y hemitiroidectomía en 2. Otros tratamientos admitidos fueron la antibioterapia sistémica o mediante irrigación intralesional y la esclerosis. Aunque en un caso la fase aguda comenzó con hipertiroidismo y tirotoxicosis, a los 6 meses del alta existió hipotiroidismo definitivo en 5 casos. Las opciones terapéuticas adoptadas consiguieron la curación en el 100% de los casos. ConclusiónLa supuración de la glándula tiroidea es una circunstancia extremadamente rara en el contexto de la enfermedad cervical, variando las opciones terapéuticas desde alternativas conservadoras al drenaje con tiroidectomía según los hallazgos microbiológicos y radiológicos. AbstractBackgroundThyroid abscess or acute suppurative thyroiditis is an unusual clinical condition. We present our experience with cases attended over 41 years. Materials and methodsA retrospective study was performed on these patients reviewing their epidemiological characteristics and the diagnostic and therapeutic manoeuvres chosen for them all, as well as their clinical outcome. A group of 9 males and 5 females was studied, with ages ranging from 19 to 68 (mean of 40.6 ± 15.4). These patients suffered 22 acute episodes, and 2 patients each had 4 episodes. ResultsSuppurative thyroiditis comprised 0.29% of the neck abscesses. Fine needle aspiration was performed in 13 cases to evacuate the collection and isolate the aetiological agent. Mycobacterium tuberculosis and Staphylococcus aureus were the most frequently identified. Nine patients underwent ultrasound and 7 computed tomography imaging studies. Surgery was the option for 10 patients, including drainage for 7, thyroidectomy for 4 and hemithyroidectomy for the remaining 2. Systemic or intralesional antibiotics and sclerosis of the gland were also carried out. Although one case presented with hyperthyroidism and thyrotoxicosis in the acute phase, definitive hypothyroidism was observed in 5 patients at 6 months following discharge. The rate of success was 100%. ConclusionThyroid gland suppuration is a very infrequent circumstance in neck pathology, and the options for its treatment are varied, from conservative to invasive techniques according to the microbial and radiologic findings. |
Recidiva de carcinoma nasosinusal relacionado con el virus del papiloma humano con características similares al adenoide quístico Publication date: March–April 2019 Source: Acta Otorrinolaringológica Española, Volume 70, Issue 2 Author(s): Andrés Felipe Sáenz González, Eduardo Morera Serna, Adriana Marcela Quintero Duarte, Rafael Ramos Asensio |
ENT-MD Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174,00302841026182,alsfakia@gmail.com
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International Journal of Environmental Research and Public Health IJERPH, Vol. 17, Pages 6976: Overcoming Barriers to Agriculture Green T...
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Calcium oxalate films on works of art: A review Publication date: Available online 14 June 2019 Source: Journal of Cultural Heritage Author...
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The conceptualization of gangs: Changing the focus Publication date: July–August 2019 Source: Aggression and Violent Behavior, Volume 47 Au...
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Increased REDD1 facilitates neuronal damage after subarachnoid hemorrhage Publication date: September 2019 Source: Neurochemistry Internati...
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