The Effect of Fractional CO2 Laser Treatment on the Symptoms of Pelvic Floor Dysfunctions: Pelvic Floor Distress Inventory‐20 Questionnaire4hby Attila Gergely Sipos, Bence Kozma, Robert Poka, Kindra Larson, Peter Takacs via Lasers in Surgery and MedicineBackground and ObjectivesTo assess the improvement on pelvic floor distress (PFD)‐related urogenital symptoms using validated questionnaires after intravaginal CO2 laser treatment.Study Design/Materials and MethodsForty postmenopausal women with genitourinary...
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Integrin αvβ6 mediates epithelial-mesenchymal transition in human bronchial epithelial cells induced by lipopolysaccharides of Pseudomonas aeruginosa via TGF-β1-Smad2/3 signaling pathway4hvia Latest Results for Folia MicrobiologicaAbstractLower respiratory tract infection due to Pseudomonas aeruginosa has become increasingly challenging, resulting in a worse morbidity and mortality. Airway remodeling is a common phenomenon in this process, to which epithelial-mesenchymal transition (EMT) may contribute...
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Monitoring 2,3',5,5'-tetrachlorobiphenyl with rapid and sensitive environmental aptamer sensor 4h...
Monitoring 2,3',5,5'-tetrachlorobiphenyl with rapid and sensitive environmental aptamer sensor4hby Siyao Liu via Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN00848A, PaperSiyao Liu, Qianqian Chen, Zhiming Wang, Tongcheng Cao, Guohua Zhao, Yongxin ZhouPolychlorinated biphenyls (PCBs) detection in the environment is significant for both the environment protection and human health....
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Pycnodysostosis: Natural history and management guidelines from 27 French cases and a literature review4hby Varoona Bizaoui, Caroline Michot, Geneviève Baujat, Cyril Amouroux, Sabine Baron, Yline Capri, Martine Cohen‐Solal, Corinne Collet, Anne Dieux, David Geneviève, Bertrand Isidor, Sophie Monnot, Massimiliano Rossi, Anya Rothenbuhler, Elise Schaefer, Valérie Cormier‐Daire via Clinical GeneticsAbstractPycnodysostosis is a lysosomal autosomal recessive skeletal dysplasia characterized by osteosclerosis,...
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Distinctive genetic variation of long‐segment Hirschsprung's disease in Taiwan4hby Wendy Yang, Szu‐Chieh Chen, Jin‐Yao Lai, Yung‐Ching Ming, Jeng‐Chang Chen, Pei‐Lung Chen via The European Gastrointestinal Motility SocietyUsing NGS in this study, we disclosed some definite harmful mutations such as a frameshift or stop codon in either familial or sporadic patients. Our cases with isolated L‐HSCR or even TCA appeared to exhibit complex patterns of inheritance and incomplete penetrance even in families...
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Molecular Carcinogenesis,Activation of a protumorigenic IFNγ/STAT1/IRF‐1 signaling pathway in keratinocytes following exposure to solar ultraviolet lightAbstract In this study, we evaluated the role of signal transducer and activator of transcription 1 (STAT1) in response to acute solar ultraviolet (SUV) radiation in mouse epidermis. Analysis of the epidermis from SUV‐irradiated mice revealed rapid phosphorylation of STAT1 (pSTAT1) on both tyrosine (tyr701) and serine (ser727) residues and increased...
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Journal of Experimental & Clinical Cancer Research,Long noncoding RNA MYOSLID promotes invasion and metastasis by modulating the partial epithelial-mesenchymal transition program in head and neck squamous cell carcinomaPartial epithelial mesenchymal transition (p-EMT) was found to play a potential role in the initial stage of metastasis in human head and neck squamous cell carcinoma (HNSCC). Some long noncoding RNAs (lncRNAs...Journal of Experimental & Clinical Cancer Research - Latest Articles3h
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PeerJ Computer Science,Recruitment of cyanobacteria by reverse transcription quantitative real-time PCR based on expression of Microcystis geneIn this study, a SYBR Green quantitative real-time PCR method was established and applied. Relative expression of the synthetic genes from Microcystis gas vesicles (gvpC), algal toxin genes (mcyA), and polysaccharides (espL) from water and sediments of Meiliang Bay and from the center of Lake Taihu were tested from January to June, 2017. Indoor Microcystis...
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The Laryngoscope,Intranasal corticosteroids and saline: Usage and adherence in chronic rhinosinusitis patientsObjective Intranasal saline irrigations and intranasal corticosteroids are supported by level‐1 evidence for medical management of chronic rhinosinusitis (CRS). We sought to study adherence with these medications. Methods Prospective study of 174 patients with CRS. Patients reported their usage of intranasal saline irrigation and intranasal corticosteroid over the preceding 3 months, at presentation,...
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Maternal and Child Health Journal,Accidental Infant Suffocation and Strangulation in Bed: Disparities and OpportunitiesAbstract Objectives (a) Update previous descriptions of trends in ASSB; (b) determine if factors previously associated with ASSB are replicated by updated data; and (c) generate new hypotheses about the occurrence of ASSB and racial inequalities in ASSB mortality. Methods National Center for Health Statistics files (International Classification of Diseases, Tenth Edition) Code W75...
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Annals of Neurology,Efficacy of Clopidogrel for Stroke Depends on CYP2C19 Genotype and Risk ProfileAbstract Objective The dual antiplatelet therapy (DAT) with clopidogrel plus aspirin has been suggested by AHA/ASA guidelines for minor stroke (MS) and transient ischemic attack (TIA) patients. The purpose of this study was to find the potential subgroups that benefit from the DAT. We aimed to compare the efficacy of clopidogrel‐aspirin therapy with aspirin therapy in MS/TIA patients stratified by CYP2C19...
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Head & Neck,Utilization of rehabilitation services in patients with head and neck cancer in the United States: A SEER‐Medicare analysisAbstract Background Head and neck cancer (HNC) and its treatment lead to functional impairments. Rehabilitation by speech‐language pathology (SLP) and occupational/physical therapy (OT/PT) can decrease morbidity. Methods The Surveillance, Epidemiology and End Results–Medicare data for patients with HNC diagnosed between 2002 and 2011 was utilized to evaluate posttreatment...
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Cancer Science,Phosphorylated STAT3 expression predicts better prognosis in smoldering type of adult T cell leukemia/lymphomaAbstract Adult T cell leukemia/lymphoma (ATLL) is a mature T cell neoplasm, and is divided into two indolent (smoldering and chronic) and two aggressive (acute and lymphoma) clinical subtypes. Based on previous integrated molecular analyses suggesting the importance of the JAK‐STAT pathway in ATLL, we attempted to clarify the clinicopathological significance of this pathway....
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Cancers,Cancers, Vol. 11, Pages 890: Leveraging the Role of the Metastatic Associated Protein Anterior Gradient Homologue 2 in Unfolded Protein Degradation: A Novel Therapeutic Biomarker for CancerCancers, Vol. 11, Pages 890: Leveraging the Role of the Metastatic Associated Protein Anterior Gradient Homologue 2 in Unfolded Protein Degradation: A Novel Therapeutic Biomarker for CancerCancers doi: 10.3390/cancers11070890Authors: Alsereihi Schulten Bakhashab Saini Al-Hejin Hussein Effective diagnostic,...
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The Journal of Antibiotics,Cyclic tetrapeptides from the marine strain <i>Streptomyces</i> sp. PNM-161a with activity against rice and yam phytopathogensThe Journal of Antibiotics - Issue - nature.com science feeds3h
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Wiley: Dermatologic Therapy,Sulfasalazine ‐ induced generalized vitiligo in a patient with dermatitis herpetiformis and celiac diseaseAbstract Vitiligo is an acquired idiopathic pigmentary skin disorder characterized by the development of white macules and patches due to the loss of functioning melanocytes. In this report we describe a case of a patient with a longstanding history of dermatitis herpetiformis and celiac disease who developed rapidly progressing, biopsy‐confirmed generalized vitiligo...
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Psycho-Oncology,Life Imprint and meaning reconstruction for young people who have experienced the death of a family member from cancerPsycho-Oncology2hShort‐term impact of breast cancer screening intervention on health‐related quality of life in China: A multicenter cross‐sectional surveyAbstract Objective The health‐related quality of life (HRQoL) impacts of participating in breast cancer screening programmes is poorly understood. Methods Based on the breast cancer screening programme, a multicentre...
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The Journal of Physiology,Maternal resveratrol administration protects against gestational diabetes‐induced glucose intolerance and islet dysfunction in the rat offspringKey points Maternal RESV administration in GDM restored normoglycemia and insulin secretion GDM‐induced obesity was prevented in male GDM+RESV offspring, but not in females GDM+RESV offspring exhibited improved glucose tolerance and insulin resistance GDM+RESV restored hepatic glucose homeostasis. Glucose‐stimulated insulin secretion...
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American Journal of Medical Genetics Part A,Anthropometrics, diet, and resting energy expenditure in Norwegian adults with achondroplasiaAbstract Individuals with achondroplasia have a high prevalence of obesity and increased risk of cardiovascular disease. Fat distribution, diet, and caloric intake are known risk factors, but the literature concerning diet and energy balance in achondroplasia is limited. The main aim of this study was to describe the anthropometrics, diet, and resting energy expenditure...
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bioRxiv Subject Collection: Evolutionary Biology,The evolution of genetic bandwagoning [NEW RESULTS]BackgroundIn separate literatures, biologists have marshaled theoretical and empirical support for theories that a variant can be selected to (1) induce suicide by moribund or otherwise stressed holders; (2) induce suicide by a holder with low productive or reproductive potential; (3) impose senescence upon a chronologically old holder; and (4) reduce the yield of a holder with low genetic heterozygosity....
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O.R.L. Journal for oto-rhino-laryngology and its borderlands,Meta-Analysis of the Effect of the Clinical Pathway Applied to Patients with Endoscopic Sinus Surgery in ChinaBackground: Chronic rhinosinusitis (CRS) is one of the most common diseases in China. The incidence of CRS in the Chinese urban population is between 5 and 15%. It is difficult to cure with traditional surgery. Endoscopic sinus surgery is the first choice for the treatment of CRS. Compared with developed countries, the development...
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Annals of Allergy, Asthma & Immunology,Combination Biologic Therapy for Severe Persistent AsthmaPublication date: Available online 25 June 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Gilbert Ortega, Pamela Tongchinsub, Tara CarrScienceDirect Publication: Annals of Allergy, Asthma & Immunology1h
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BioMed Research International,Systematic Review and Meta-Analysis of 12 Randomized Controlled Trials Evaluating the Efficacy of Invasive Radiofrequency Treatment for Knee Pain and FunctionRadiofrequency (RF) treatment is an invasive and promising procedure in the treatment of osteoarthritis (OA). A meta-analysis based on 12 RCT studies was to investigate whether invasive RF treatment is more effective in relieving knee pain and improving knee function. Relevant studies were searched on database of...
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Annals of Allergy, Asthma & Immunology,Editorial BoardAnnals of Allergy, Asthma & Immunology1hTable of ContentsAnnals of Allergy, Asthma & Immunology1hInformation for AuthorsAnnals of Allergy, Asthma & Immunology1hDrug AllergyFor this edition of Annals, focusing on Drug Allergy, From Pages of Allergy Watch highlights reviews of articles that concentrate on reactions to medications. The initial report investigates the impact of PPI and antibiotics that can impact the microbiome on...
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Thyroid,Performance of ATA Risk Stratification Systems, Response to Therapy, and Outcome in an Indian Cohort of Differentiated Thyroid Carcinoma Patients: A Retrospective StudyIntroduction: For better individualized management of differentiated thyroid carcinoma (DTC), ATA risk stratification systems (RSS) of 2009 and 2015 as well as a response to therapy re-classification (ATA RTR-2015) are used worldwide for assessing risk of recurrence. But there are no validation studies of these systems from...
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The Scientific World Journal,Characterization and Quantification of Heavy Metals in Oued Sebou SedimentsThe discharge of large quantities of industrial and domestic effluents into the estuaries, with or without treatment, has led to an increase in the amount of micropollutants present in the sediments. In this study, we have assessed the quality of sediments of Sebou river studying the physicochemical parameters, percentage of organic matter, mineralogy, and trace levels of metal elements trapped...
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American Journal of Primatolog,Metagenomic assessment of the Cebus apella gut microbiotaAbstract Cebus Apella (C. apella) is a species of Nonhuman Primate (NHP) used for biomedical research because it is phylogenetically similar and shares anatomical commonalities with humans. Here, the gut microbiota of three C. apella were examined in the different regions of the intestinal tract. Using metagenomics, the gut microbiota associated with the luminal content and mucus layer for each intestinal region...
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Cranio-Maxillofacial Surgery,Parotid pleomorphic adenomas: factors influencing surgical techniques, morbidity, and long-term outcome relative to the new ESGS classification in a retrospective studyPublication date: Available online 26 June 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Mirco Schapher, Michael Koch, Abbas Agaimy, Miguel Goncalves, Konstantinos Mantsopoulos, Heinrich IroSummaryPurposeTo assess long-term results after treatment of parotid pleomorphic adenomas (PPAs)...
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Journal of Biophotonics,Photobiomodulation using low level 808 nm diode laser rescues cochlear synaptopathy after acoustic overexposure in ratAbstract A certain degree of noise can cause hearing problems without a permanent change in the hearing threshold, which is called hidden hearing loss and results from partial loss of auditory synapses. Photobiomodulation (PBM) enhances neural growth and connections in the peripheral nervous systems. In this study, we assessed whether PBM could rescue cochlear...
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Evaluation of Maxillary Sinus Volume and Surface Area in Children with β-thalassaemia Using Cone Beam Computed Tomography1hvia Pediatric OtorhinolaryngologyPublication date: Available online 25 June 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Mahmut Koparal, Eda Didem Yalcın, Orhan Aksoy, Ayse Ozcan-KucukAbstractObjectivesAmong children with β-thalassaemia, skeletal changes and abnormalities, such as decreased volume or obliteration of the sinus, result primarily...
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The Hydrogenobyric Acid Structure Reveals the Corrin Ligand as an Entatic State Module Empowering B12 Cofactors for CatalysisHydrogenobyric acid, the metal‐free corrin ligand of the natural B12 derivatives, has been prepared via an engineered biosynthesis. Its structure revealed a uniquely ring‐contracted and strongly helical ligand cavity. It binds cobalt ions tightly in an entatic state strained by coordinative misfit. This activates the B12 cofactors for homolytic and reductive cleavage of their...
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Pediatric Otorhinolaryngology,Is vessel narrowing secondary to pediatric deep neck space infections of clinical significance?Publication date: Available online 26 June 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): William Carroll, Jenna Van Beck, Brianne RobyAbstractIntroductionPediatric deep neck space infections (DNSI) may cause internal jugular vein and/or carotid artery narrowing. Radiologists and otolaryngologists are often queried by emergency room providers...
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Otorhinolaryngology,Post-thyroidectomy Horner's syndromePublication date: Available online 26 June 2019Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): M. Perréard, H. Bailleul, E. BabinOtorhinolaryngology1hSoft swelling of the external auditory canalPublication date: Available online 26 June 2019Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): G. Ciavarro, M. FalcioniOtorhinolaryngology1h
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Asiatic acid inhibits cardiac fibrosis throughNrf2/HO-1 and TGF-β1/Smads signaling pathways in spontaneous hypertension rats1hvia ScienceDirect Publication: International ImmunopharmacologyPublication date: September 2019Source: International Immunopharmacology, Volume 74Author(s): Zhe Meng, Hai-yu Li, Chun-ying Si, Yu-zhou Liu, Shuai TengAbstractObjectiveAsiatic acid (AA) has been suggested to inhibit pulmonary and hepatic fibrosis, while its influence on cardiac fibrosis remains unclear. We aimed...
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Eosinophilic pneumonia: A review of the previous literature, causes, diagnosis, and management 1h...
Eosinophilic pneumonia: A review of the previous literature, causes, diagnosis, and management1hvia Allergology InternationalPublication date: Available online 25 June 2019Source: Allergology InternationalAuthor(s): Yuzo Suzuki, Takafumi SudaAbstractEosinophilic pneumonia (EP) is a rare disorder, comprising several heterogeneous diseases. Two major types of EP are acute eosinophilic pneumonia (AEP) and chronic eosinophilic pneumonia (CEP), both of which are characterized by marked accumulation of...
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Effects of body temperature on the expression and localization of meiosis-related proteins STRA8 and SCP3 in boar testes1hvia Acta HistochemicaPublication date: Available online 26 June 2019Source: Acta HistochemicaAuthor(s): Meishan Yue, Xiaorui Fan, Yihui Liu, Weidong Yue, Gaoya Ren, Jingwen Zhang, Xinrong Zhang, Qinghong Li, Junping HeAbstractBody temperature could lead to interruption of spermatogenesis, but the molecular mechanism was still unclear. Cryptorchidism was defined as the failure...
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Dental health status and oral health behaviours of patients with facial burn in Pakistan58mvia Latest Results for BMC Oral HealthAbstractBackgroundThere is a limited understanding about the oral health of patients with facial burn, hence the aim was to describe the oral health status and the related risks factors.MethodsThis cross-sectional study had randomly and systematically recruited facial burn patients from the Burn Care Center, Pakistan Institute of Medical Sciences, Islamabad, from June of...
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Biomedicine & Pharmacotherapy,Flos <em>Abelmoschus manihot</em> extract attenuates DSS-induced colitis by regulating gut microbiota and Th17/Treg balancePublication date: September 2019Source: Biomedicine & Pharmacotherapy, Volume 117Author(s): Wei Zhang, Cheng Cheng, Qin Han, Yugen Chen, Jianming Guo, Qinan Wu, Bo Zhu, Jinjun Shan, Liyun ShiAbstractFlos Abelmoschus manihot is widely used as traditional drug in China. Abelmoschus manihot (AM) extracted from Flos Abelmoschus manihot...
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Real-Time Acoustic Voice Analysis Using a Handheld Device Running Android Operating System22mvia VoicePublication date: Available online 26 June 2019Source: Journal of VoiceAuthor(s): Shintaro Fujimura, Tsuyoshi Kojima, Yusuke Okanoue, Hiroki Kagoshima, Atsushi Taguchi, Kazuhiko Shoji, Masato Inoue, Ryusuke HoriSummaryObjectivesWe developed a highly accessible acoustic voice analysis system (VArt) using a handheld device running Android operating system. To provide stable and reliable analysis using...
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Researchers 3D Print Materials to Mimic Soft Tissues and Create Custom Braces21mby Medgadget Editors via Medgadget3D printing is already widely utilized in medicine during cardiac surgeries, to make orthopedic implants, and as guides to accurately put them in place. Typically, the devices that are printed are rigid, but the body is mostly made of soft tissues.Engineers at MIT have been working on offering clinicians a way to use additive manufacturing, another name for 3D printing, to make customizable...
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Comparison of Contrast-Enhanced Tomographic 3-D Ultrasound Against Rotational Angiography Imaging Immediately After Endovascular Aneurysm Repair16mvia Ultrasound in Medicine & BiologyPublication date: Available online 26 June 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Steven Rogers, Christopher Lowe, Joao Carreira, Charles McCollum, Jonathan GhoshAbstractThis proof of principle study assesses the utility of contrast-enhance ultrasound (CEUS) and contrast-enhanced tomographic 3-D...
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Practical Radiation Oncology,Erratum to: Royce TJ. What's in a Name? <em>Pract Radiat Oncol</em>. 9(3): 125-127, 2019Publication date: Available online 26 June 2019Source: Practical Radiation OncologyAuthor(s): Trevor J. RoycePractical Radiation Oncology13mComparison of Motion-insensitive T2-weighted MRI Pulse Sequences for Visualization of the Prostatic Urethra during MR SimulationPublication date: Available online 25 June 2019Source: Practical Radiation OncologyAuthor(s): Kristen L....
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Journal of Cranio-Maxillofacial Surgery,Parotid pleomorphic adenomas: factors influencing surgical techniques, morbidity, and long-term outcome relative to the new ESGS classification in a retrospective studyPublication date: Available online 26 June 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Mirco Schapher, Michael Koch, Abbas Agaimy, Miguel Goncalves, Konstantinos Mantsopoulos, Heinrich IroSummaryPurposeTo assess long-term results after treatment of parotid pleomorphic adenomas...
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