Antioxidants Antioxidants, Vol. 8, Pages 288: Spotlight on a New Heme Oxygenase Pathway: Testosterone-Induced Shifts in Cardiac Oxidant/Antioxidant StatusAntioxidants, Vol. 8, Pages 288: Spotlight on a New Heme Oxygenase Pathway: Testosterone-Induced Shifts in Cardiac Oxidant/Antioxidant Status Antioxidants doi: 10.3390/antiox8080288 Authors: Renáta Szabó Denise Börzsei Krisztina Kupai Alexandra Hoffmann Rudolf Gesztelyi Anikó Magyariné Berkó Csaba Varga Anikó Pósa A low testosterone level contributes...
International Journal of Molecular Sciences IJMS, Vol. 20, Pages 3847: Matrix Metalloproteases as Influencers of the Cells' Social MediaIJMS, Vol. 20, Pages 3847: Matrix Metalloproteases as Influencers of the Cells' Social Media International Journal of Molecular Sciences doi: 10.3390/ijms20163847 Authors: Daniel Young Nabangshu Das Anthonia Anowai Antoine Dufour Matrix metalloproteinases (MMPs) have been studied in the context of cancer due to their ability to increase cell invasion, and were initially...
Antibiotics, Vol. 8, Pages 111: Blocking the Trigger: Inhibition of the Initiation of Bacterial Chromosome Replication as an Antimicrobial StrategyAntibiotics, Vol. 8, Pages 111: Blocking the Trigger: Inhibition of the Initiation of Bacterial Chromosome Replication as an Antimicrobial Strategy Antibiotics doi: 10.3390/antibiotics8030111 Authors: Julia E. Grimwade Alan C. Leonard All bacterial cells must duplicate their genomes prior to dividing into two identical daughter cells. Chromosome replication...
International Journal of Surgery Search for the best site in islet xenotransplantation.Related ArticlesSearch for the best site in islet xenotransplantation. Int J Surg. 2019 Aug 02;: Authors: Ekser B, Vagefi PA Abstract It can reasonably be anticipated that, within 5-10 years, islet allotransplantation or pig islet xenotransplantation may be the preferred options for ß-cell replacement therapy. The portal vein/liver is currently the preferred clinical site for free islet transplantation, constituting...
European Journal of Vascular and Endovascular Surgery Factors Associated with Hospital Dependent Delay to Carotid Endarterectomy in the Dutch Audit for Carotid InterventionsPublication date: Available online 6 August 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Laurien S. Kuhrij, Armelle J.A. Meershoek, Eleonora G. Karthaus, Anco C. Vahl, Jaap F. Hamming, Paul J. Nederkoorn, Gert Jan de BorstObjectivesAs the risk of a recurrent neurological event in patients with symptomatic...
Neonatal retropharyngeal abscess with complications: Apnea and cervical osteomyelitis.Related ArticlesNeonatal retropharyngeal abscess with complications: Apnea and cervical osteomyelitis. Int J Pediatr Otorhinolaryngol. 2019 Jul 31;126:109613 Authors: Ali NE, Alyono JC, Koltai PJ Abstract OBJECTIVE: To evaluate the clinical presentation and management strategies for neonatal retropharyngeal abscess (RPA). METHODS: Retrospective chart review was performed, and literature reviewed. RESULTS: We report...
Triple Trouble: A Case of Multiple Resistance Mechanisms after First Generation EGFR-TKI in NSCLC...
Triple Trouble: A Case of Multiple Resistance Mechanisms after First Generation EGFR-TKI in NSCLCEpidermal growth factor receptor (EGFR)-targeted therapy has become standard of care in advanced stages EGFR-mutant non-small cell lung cancer. Acquired resistance to first-line EGFR-tyrosine kinase inhibitor (TKI) and subsequent disease progression is a common problem and mostly due to a secondary mutation (T790M) in EGFR. We report a case of a patient with EGFR-mutated lung adenocarcinoma who developed...
Proteomics analysis of asthenozoospermia and identification of glucose-6-phosphate isomerase as an important enzyme for sperm motilityPublication date: Available online 5 August 2019Source: Journal of ProteomicsAuthor(s): Yueshuai Guo, Wen Jiang, Weiling Yu, Xin Niu, Fangjuan Liu, Tao Zhou, Hao Zhang, Yan Li, Hui Zhu, Zuomin Zhou, Jiahao Sha, Xuejiang Guo, Daozhen ChenAbstractAsthenozoospermia, in which sperm motility is affected, is one of the primary causes of male infertility. However, the exact...
Innovation by Computer-Aided Design/Computer-Aided Manufacturing Technology: A Look at Infection Prevention in Dental SettingsRecent data indicates limited awareness and compliance on infection prevention procedures by dental offices and by dental laboratories. Guidelines for infection prevention in dentistry have been published by Centres for Disease Control and Prevention since 2003; the section "IX-Special consideration" includes a subsection concerning the prevention in dental laboratories, but...
Teaching Basic Knowledge on Substance Use Disorders: the Impact of e-Learning on Health Professionals17hvia Clinical TherapeuticsPublication date: Available online 5 August 2019Source: Clinical TherapeuticsAuthor(s): Emilie Jouanjus, Maryse Lapeyre-Mestre, Matthieu Nodot, Anne Roussin, Nicolas Franchitto, Jean-Paul Boyes, Nathalie Nasr, Stéphane Oustric, Julie DupouyAbstractPurposeRecent evolution toward a medical perspective on patients with substance use disorders (SUDs) has led to a lack of medical...
Evaluation of antibacterial activity of propolis on regenerative potential of necrotic immature permanent teeth in dogsAbstract Background This study evaluated the antibacterial efficiency and ability of propolis to promote regeneration of immature permanent non-vital dogs' teeth. Methods Ninety six immature permanent premolars teeth in 6 mongrel dogs were divided randomly into: experimental teeth (N = 72) and control teeth (N = 24). Periapical pathosis was...Latest Results for BMC Oral Health16hEffect...
Anatomical feature of knee joint in Aachen minipig as a novel miniature pig line for experimental...
Anatomical feature of knee joint in Aachen minipig as a novel miniature pig line for experimental research in orthopaedicsPublication date: Available online 5 August 2019Source: Annals of Anatomy - Anatomischer AnzeigerAuthor(s): Gundula Schulze-Tanzil, Sandeep Silawal, Mariann HoyerAbstractBackgroundThe pig is a commonly used large animal model, since pigs share anatomical and physiological similarities with humans. In contrast to other experimental pig lines the Aachen minipig, as a robust novel...
Developmental milestones and behavior of infant rats: The role of sensory input from whiskersPublication date: Available online 6 August 2019Source: Behavioural Brain ResearchAuthor(s): Kirill Smirnov, Evgenia SitnikovaAbstractDevelopmental milestones are behavioral and physical skills which are considered as markers of neurodevelopment. In rodents, sensory input from whiskers plays a crucial role in development of brain functions. Development of whisker system in rats includes the early period of...
Hydrogen peroxide inducible clone-5 sustains NADPH oxidase-dependent reactive oxygen species-c-jun N-terminal kinase signaling in hepatocellular carcinoma15hvia Oncogenesis - nature.com science feeds
SCORE – Leveling the Playing Field for Surgical Training Programs15hvia Journal of Surgical EducationPublication date: Available online 5 August 2019Source: Journal of Surgical EducationAuthor(s): Emily Jean Onufer, Anne Trolard, Mark Hickey, William Lyons, Mary E. Klingensmith, Mark A. Malangoni, Amit R.T. JoshiObjectiveThe Surgical Council on Resident Education (SCORE) web portal provides a uniform, comprehensive, competency-based curriculum for general surgery residents. One of SCORE's principal...
L'annonce d'un décès en milieu hospitalier15hvia ScienceDirect Publication: Médecine & DroitTranslate articlePublication date: Available online 5 August 2019Source: Médecine & DroitAuthor(s): Lisa De LimaRésuméL'annonce d'un décès étant toujours un moment délicat pour les proches et le personnel, la loi apporte de légères précisions sur les modalités d'une telle information. Récemment, le Conseil d'État a également reconnu un préjudice du fait du manque d'empathie du personnel et de l'annonce...
Pregnancy-associated breast cancer: A review of 47 women15hvia Clinical ImagingPublication date: Available online 5 August 2019Source: Clinical ImagingAuthor(s): Fusun Taskin, Yasemin Polat, İbrahim H. Erdoğdu, Aykut SoyderAbstractPurposePregnancy-associated breast cancer (PABC) is a rare disease. However, its expected incidence tends to be increased because of delayed maternal age. The purpose of this study was to describe the clinical, radiological, and histopathological characteristics of PABC...
Rectal cancer lexicon: consensus statement from the society of abdominal radiology rectal & anal cancer disease-focused panel13hvia Latest Results for Abdominal RadiologyAbstractStandardized terminology is critical to providing consistent reports to referring clinicians. This lexicon aims to provide a reference for terminology frequently used in rectal cancer and reflects the consensus of the Society of Abdominal Radiology Disease Focused Panel in Rectal cancer. This lexicon divided the terms...
The evolution of intergroup tolerance in nonhuman primates and humans14hby Anne C. Pisor, Martin Surbeck via Wiley: Evolutionary Anthropology: Issues, News, and Reviews: Table of ContentsAbstractPrimate individuals use a variety of strategies in intergroup encounters, from aggression to tolerance; however, recent focus on the evolution of either warfare or peace has come at the cost of characterizing this variability. We identify evolutionary advantages that may incentivize tolerance toward extra‐group...
Back Brace Simulator Uses 3D Prints of Patient Spine and Rib CageThe development of innovative back braces has stagnated a bit. In part, this is because different patients have unique needs and there isn't a comprehensive platform to test how new braces will help support different anatomies. Now, a team of engineers at Lancaster University in the U.K. has developed a torso simulator that can help researchers to design new back braces that are perfectly tuned to the needs of different people. The...
Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and...
Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.Related ArticlesNovel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis. Eur J Med Chem. 2019 Jul 28;181:111541 Authors: Huang Z, Zhao B, Qin Z, Li Y, Wang T, Zhou W, Zheng J, Yang S, Shi Y, Fan Y, Xiang R Abstract Based on the significantly synergistic effects of CDK4 and VEGFR2 inhibitors on growth of cancer cells, a series of novel...
The ESMO clinical practise guidelines for early breast cancer: diagnosis, treatment and follow-up: on the winding road to personalized medicineS LoiAnnals of Oncology, Volume 30, Issue 8, August 2019, Pages 1183–1184, https://doi.org/10.1093/annonc/mdz201Published: 09 July 2019CitePermissions Icon Permissions ShareIssue Section: EditorialsIn this issue of Annals, Cardoso et al. [1], formulate concise and succinct recommendations for early breast cancer management, which will be a valuable resource...
A cepstrum analysis-based classification method for hand movement surface EMG signals6hvia Latest Results for MedicalAbstractIt is of great importance to effectively process and interpret surface electromyogram (sEMG) signals to actuate a robotic and prosthetic exoskeleton hand needed by hand amputees. In this paper, we have proposed a cepstrum analysis-based method for classification of basic hand movement sEMG signals. Cepstral analysis technique primarily used for analyzing acoustic and seismological...
G3: .Genes, Genomes, Genetics Mission - Online First ArticlesIslandCafe: Compositional Anomaly and Feature Enrichment Assessment for Delineation of Genomic IslandsOne of the evolutionary forces driving bacterial genome evolution is the acquisition of clusters of genes through horizontal gene transfer (HGT). These genomic islands may confer adaptive advantages to the recipient bacteria, such as, the ability to thwart antibiotics, become virulent or hypervirulent, or acquire novel metabolic traits....
Imaging Primary myelofibrosis: spectrum of imaging features and disease-related complicationsAbstract Primary myelofibrosis is a chronic clonal stem cell disorder that results in a build-up of marrow fibrosis and dysfunction, hypermetabolic states, and myeloid metaplasia. The clinical and radiological consequences can be quite diverse and range from the manifestations of osteosclerosis and extramedullary haematopoiesis to thrombohaemorrhagic complications from haemostatic dysfunction. In addition,...
Chronic Respiratory Disease: The similarities and differences between pleuroparenchymal fibroelastosis and idiopathic pulmonary fibrosisChronic Respiratory Disease, Volume 16, Issue , January-December 2019. The idiopathic form of pleuroparenchymal fibroelastosis (PPFE) is categorized as a rare idiopathic interstitial pneumonia in the current classification. The majority of PPFE cases are idiopathic, but many predisposing factors or comorbidities have been reported. Although histological PPFE is predominantly...
Applied Microbiology and BiotechnologyTime-dependent effects of Pochonia chlamydosporia endophytism on gene expression profiles of colonized tomato rootsAbstract A transcriptome analysis was produced from tomato roots inoculated with the hyphomycete Pochonia chlamydosporia at three different times. Gene expression data were also yielded from fungus grown in vitro or endophytic. A next-generation sequencing (NGS) and network analysis approach were applied. We identified 3.676 differentially expressed...
bioRxiv Subject Collection: Evolutionary BiologyResolving genetic linkage reveals patterns of selection in HIV-1 evolution [NEW RESULTS]Identifying the genetic drivers of adaptation is a necessary step in understanding the dynamics of rapidly evolving pathogens and cancer. However, signals of selection are obscured by the complex, stochastic nature of evolution. Pervasive effects of genetic linkage, including genetic hitchhiking and clonal interference between beneficial mutants, challenge our ability...
Extended evaluation of the efficacy of a proactive forced oscillation technique-based auto-CPAP algorithmAbstract Purpose Previous studies revealed substantially varying therapy efficacy of automatic continuous positive airway pressure (APAP) devices in the treatment of obstructive sleep apnea (OSA). We evaluated the efficacy of a new APAP device using the forced oscillation technique (FOT) to evaluate upper airway obstruction during apneas and flow contour analyses during hypopneas. ...Latest Results...
Utilization Patterns of Facet Joint Interventions in Managing Spinal Pain: a Retrospective Cohort...
Utilization Patterns of Facet Joint Interventions in Managing Spinal Pain: a Retrospective Cohort Study in the US Fee-for-Service Medicare PopulationAbstract Purpose of Review To assess patterns of utilization and variables of facet joint interventions in managing chronic spinal pain in a fee-for-service (FFS) Medicare population from 2009 to 2016, with a comparative analysis from 2000 to 2009 and 2009 to 2016. Recent Findings From 2009 to 2016, facet joint interventions increased at an...Headache...
Exon 3-deleted growth hormone receptor isoform is not related to worse bone mineral density or microarchitecture or to increased fracture risk in acromegalyAbstract Purpose Acromegaly is a cause of secondary osteoporosis and is associated with increased risk of vertebral fractures (VFs). The influence of exon 3-deleted isoform of growth hormone receptor (d3-GHR) on bone microarchitecture has not been studied in acromegaly. Aim The aim of this study was to analyze the associations between d3-GHR isoform...
Medullary ischemia after endovascular procedure of infrarenal aorta in a patient with dual anticoagulant and antiplatelet therapy: a case reportMedullary ischemia secondary to surgical procedures of the infrarenal aorta is an infrequent and mostly devastating complication of this procedure, and its nonspecific clinical presentation makes it difficult ...Journal of Medical Case Reports - Latest Articles11hHyaluronic Acid as an Alternative to Autologous Human Serum Eye Drops: Initial Clinical Results...
Embolization of iliac metastasis during lenvatinib treatment in patient with advanced Hürthle cell thyroid carcinomaFuture Oncology, Ahead of Print.Future Oncology1hCase report: lenvatinib in neoadjuvant setting in a patient affected by invasive poorly differentiated thyroid carcinomaFuture Oncology, Ahead of Print.Future Oncology1hLong-term disease control and high clinical benefit in a patient with advanced thyroid cancer treated with lenvatinibFuture Oncology, Ahead of Print.Future Oncology1hLenvatinib...
Muscular Contribution to Adolescent Idiopathic Scoliosis from the Perspective of Stem Cell-Based Regenerative MedicineStem Cells and Development, Volume 28, Issue 16, Page 1059-1077, August 15, 2019.Stem Cells and Development1hPhotodynamic therapy for basal cell carcinoma of external auditory canal: a case reportPublication date: Available online 6 August 2019Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Shengjing Xu, LingLi Zhang, Min ZhangAbstractBackgroundBasal cell carcinoma (BCC)...
Cloning of novel bacterial xylanases from lignocellulose-enriched compost metagenomic librariesXylanases are in important class of industrial enzymes that are essential for the complete hydrolysis of lignocellulosic biomass into fermentable sugars. In the present study, we report the cloning of novel xy...Applied and Industrial Microbiology9hVancomycin-resistant Staphylococcus aureus isolated from camel meat and slaughterhouse workers in EgyptThe emergence of vancomycin-resistant Staphylococcus aureus...
3D-based full-guided ridge expansion osteotomy - a case report about a new method with successive...
3D-based full-guided ridge expansion osteotomy - a case report about a new method with successive use of different surgical guides, transfer of splitting vector and simultaneous implant insertionPublication date: Available online 5 August 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Hans-Joachim Nickenig, Ali-Farid Safi, Ragai-Edward Matta, Joachim E. Zöller, Matthias KreppelAbstractFor horizontal bone deficiency alveolar ridge osteotomy is considered an option for augmentation....
Isolation of Specific Neuron Populations from Roundworm Caenorhabditis elegansHere, we present a protocol for simple isolation of specific groups of live neuronal cells expressing green fluorescent protein from transgenic Caenorhabditis elegans lines. This method enables a variety of ex vivo studies focused on specific neurons and has the capacity to isolate cells for further short-term culturing.JoVE: Journal of Visualized Experiments11hCone Beam Intraoperative Computed Tomography-based Image Guidance...
A Preliminary Cohort Study Assessing Routine Blood Analyte Levels and Neurological Outcome after Spinal Cord InjuryJournal of Neurotrauma, Ahead of Print.Journal of Neurotrauma3hDextran 500 Improves Recovery of Inflammatory Markers: An In Vitro Microdialysis StudyJournal of Neurotrauma, Ahead of Print.Journal of Neurotrauma3hWhy is middle cerebral artery plaque augmented by contrast media? A phantom study using middle cerebral artery stenotic silicon modelAbstract Purpose The pathophysiologic mechanisms...
Effect of four weeks of ocular-motor exercises on dynamic visual acuity and stability limit of female basketball playersPublication date: September 2019Source: Gait & Posture, Volume 73Author(s): Hooman Minoonejad, Amir Hossein Barati, Homa Naderifar, Bijan Heidari, Amir Shamloo Kazemi, Alireza LashayAbstractIntroductionVisual skills are an integral part of most daily activities and an effective indicator of the functional ability of athletes, particularly in the fields of dynamic sports like...
Lactate Dehydrogenase-to-Lymphocyte Ratio Represents a Powerful Prognostic Tool of Metastatic Renal Cell Carcinoma Patients Treated with Tyrosine Kinase InhibitorsAbstract Inflammation parameters were verified to predict clinical outcomes of metastatic renal cell carcinoma (mRCC) patients treated with tyrosine kinase inhibitors (TKIs). Here, we developed a novel marker, lactate dehydrogenase (tumor burden marker) to lymphocytes (inflammation marker) ratio (LLR), aimed to reveal the prognostic role...
The Long Night of Jacob Twenty years after Jacob deceived his brother Esau and fled, he finally comes home. As Jacob prepares to meet Esau, he encounters God! A mysterious man (ish) wrestles with him—and Jacob becomes Israel. Jacob names the place Peniel (פניאל)- Face of God. Then we read, "The sun rose upon him as he passed Peniel" (Gen.32:31). What is the secret meaning of this "rising sun"?Discoverוַיִּוָּתֵר יַעֲקֹב לְבַדּוֹ וַיֵּאָבֵק אִישׁ עִמּוֹ עַד עֲלוֹת הַשָּׁחַר. וַיַּרְא כִּי לֹא יָכֹל...
Case Studies in Social Medicine: The Right and Left Hands of the State — Two Patients at Risk of...Case Studies in Social Medicine: The Right and Left Hands of the State — Two Patients at Risk of DeportationA. Berlin and OthersN Engl J Med 381:197, July 18, 2019Audio | CommentsORIGINAL ARTICLENeural-Tube Defects and Antiretroviral Treatment Regimens in BotswanaR. Zash and OthersN Engl J Med, July 22, 2019Transfusion Volume for Children with Severe Anemia in AfricaK. Maitland and OthersN Engl J Med...
The Heterogeneous Landscape of Head & Neck Squamous Cell CarcinomasNo abstract availableFinding a Cure for Children With CNS NeuroblastomaNo abstract availableEHR Tool Finds Pediatric Leukemia Patients for Clinical StudiesNo abstract availableIn Search of an Immunotherapy Innovation for Ovarian CancerNo abstract availableChildhood Leukemia Cannot Hide From Immune SystemNo abstract availableUpToDate®No abstract availableEnzalutamide Improved Survival in Metastatic Prostate CancerNo abstract availableOlaparib...
Endoscopic Transgastric Versus Surgical Approach for Infected Necrotizing Pancreatitis: A Systematic Review and Meta-AnalysisSurgical approach (SA) is the standard treatment for infected necrotizing pancreatitis (INP) and endoscopic transgastric approach (ETA) is a promising alternative treatment. This systematic review and meta-analysis aimed to compare the effectiveness and safety of ETA versus SA in INP. Several databases were systematically searched for eligible studies that compared ETA with...
Norfloxacin, ciprofloxacin, trimethoprim–sulfamethoxazole, and rifaximin for the prevention of spontaneous bacterial peritonitis: a network meta-analysisFor the prevention of spontaneous bacterial peritonitis (SBP) in cirrhotic patients with ascites, prophylactic antibiotics are recommended as a standard regimen. This study aimed to assess the efficacy of norfloxacin (N), ciprofloxacin (C), trimethoprim–sulfamethoxazole (T-S), and rifaximin (R) in the prevention of SBP. We searched the electronic...
Sponsorship by Big Oil, Like the Tobacco Industry, Should be Banned by the Research CommunityNo abstract availableFine Particulate Air Pollution and Birthweight: Differences in Associations Along the Birthweight DistributionBackground: Maternal exposure to fine particulate air pollution (PM2.5) during pregnancy is associated with lower newborn birthweight, which is a risk factor for chronic disease. Existing studies typically report the average association related with PM2.5 increase, which does...
Beneficial effect of ticagrelor on microvascular perfusion in patients with ST-segment elevation myocardial infarction undergoing a primary percutaneous coronary interventionBackground Ticagrelor significantly reduced the incidence of death, myocardial infarction, and stent thrombosis in patients with ST-segment elevation myocardial infarction (STEMI) intended for reperfusion with a primary percutaneous coronary intervention (pPCI). However, the effects of this drug on microvascular perfusion in...
Prospects for pharmacotherapies to treat alcohol use disorder: an update on recent human studies Purpose...Prospects for pharmacotherapies to treat alcohol use disorder: an update on recent human studiesPurpose of review The aim of this study was to provide an update on medication development efforts for alcohol use disorder (AUD) by reviewing recently published (past 2 years) human studies that evaluated medications' effects on alcohol-related outcomes. Recent findings Forty-five publications were...
Routine cardiac troponin assessment after percutaneous coronary intervention: useful or hype?Although the angiographic and procedural success of percutaneous coronary intervention (PCI) is now very high, some severe complications may still develop, including periprocedural myocardial infarction (MI). An accurate diagnosis of this condition is essential for guiding the clinical management, as these patients may need a tailored management. The current recommendations for diagnosing periprocedural myocardial...
Molecules, Vol. 24, Pages 2837: Bioavailability and Bioactivity of Encapsulated Phenolics and Carotenoids Isolated from Red Pepper WasteMolecules, Vol. 24, Pages 2837: Bioavailability and Bioactivity of Encapsulated Phenolics and Carotenoids Isolated from Red Pepper Waste Molecules doi: 10.3390/molecules24152837 Authors: Jelena Vulić Vanja Šeregelj Ana Kalušević Steva Lević Viktor Nedović Vesna Tumbas Šaponjac Jasna Čanadanović-Brunet Gordana Ćetković In order to deactivate the health properties...
A game of colours, changing emotions in children: a pilot study AbstractAim To analyse the effect...
A game of colours, changing emotions in children: a pilot studyAbstractAimTo analyse the effect of colours on children's emotions and variations in anxiety levels using six different coloured attires, white, pink, yellow, green, purple and black.MethodsSeventy-two children aged between 5–9 years old who had come for restorative treatment in the Department of Paediatric and Preventive Dentistry, I.T.S. Dental College, Muradnagar, Ghaziabad, India were chosen and divided according to Corah's dental...
Exploring the use of network meta-analysis in education: examining the correlation between ORF and text complexity measuresAbstractCalls for empirical investigations of the Common Core standards (CCSSs) for English Language Arts have been widespread, particularly in the area of text complexity in the primary grades (e.g., Hiebert & Mesmer Educational Research, 42(1), 44–51, 2013). The CCSSs mention that qualitative methods (such as Fountas and Pinnell) and quantitative methods (such as Lexiles)...
Australasian Journal of Dermatology Volume 60, Issue 3Pages: 175-257, e173-e266 August 2019 Issue...
Australasian Journal of DermatologyVolume 60, Issue 3Pages: 175-257, e173-e266August 2019Issue InformationIssue InformationPages: 175-180 | First Published: 01 August 2019REVIEW ARTICLESEfficacy and safety of oral atenolol for the treatment of infantile haemangioma: A systematic reviewQi Wang, Bo Xiang, Siyuan Chen, Yi JiPages: 181-185 | First Published: 04 December 2018Dysplastic/Clark naevus in the era of molecular pathologyNima Mesbah ArdakaniPages: 186-191 | First Published: 10 March 2019The...
British Journal of Dermatology Volume 181, Issue 2Pages: i-ix, 229-427, e31-e56 August 2019 Issue...
British Journal of DermatologyVolume 181, Issue 2Pages: i-ix, 229-427, e31-e56August 2019Issue InformationIssue InformationPages: i-vi | First Published: 01 August 2019Editor's ChoiceEditor's ChoicePages: ix | First Published: 01 August 2019EDITORIALSRecognizing the differential impact of site of involvement on quality of life in dermatologyP. GisondiPages: 229-230 | First Published: 01 August 2019Linked Article: Augustin et al. Br J Dermatol 2019; 181:358–365.PROCLIPI: a step in the right direction...
KOMBINATIONSTHERAPIE TECENTRIQ MIT AVASTINDie randomisierte offene Phase-III-Studie IMpower150 untersuchte die Wirksamkeit und Sicherheit von Tecentriq in Kombination mit Avastin und Chemotherapie in der First-Line-Therapie des lokal fortgeschrittenen und metastasierten NSCLC mit nicht-plattenepithelialer Histologie.4,8 Im Anschluss an eine Induktionsphase von vier oder sechs Zyklen erhielten die Patienten eine chemotherapiefreie Erhaltungstherapie aus Tecentriq und Avastin. Eine Besonderheit der...
NEUER THERAPIESTANDARD BEI LEBERMETASTASEN UND EGFR-MUTATION?Experten sprechen bereits davon, dass sich die Vierfachkombination aus Tecentriq, Avastin und Chemotherapie als neuer Therapiestandard bei bestimmten Patientengruppen etablieren wird:3,6,7"Nach meiner Einschätzung blicken wir einem neuen Therapiestandard bei Patienten mit Lebermetastasierung und Patienten mit EGFR-Mutation nach TKI-Versagen entgegen."Prof. Dr. Christian Schulz, Regensburg"Die IMpower150-Studie setzt neue Maßstäbe in der...
MORTALITÄTSRISIKO BEI NSCLC-PATIENTEN MIT LEBERMETASTASEN NAHEZU HALBIERTIn der jüngst auf dem ASCO vorgestellten Subgruppenanalyse der IMpower150-Studie wurden 162 Patienten der ITT-Population mit Lebermetastasen (Follow-up von mind. 20 Monaten) berücksichtigt.1 Diese Patienten hatten im Median eine Filialisierung an drei verschiedenen Lokalisationen und zur Baseline eine mediane Summe des längsten Durchmessers (SLD) der Target-Läsionen von 109 mm (Range: 10-249 mm). Die Vierfachkombination aus...
Serious clinical events in HIV-positive persons with chronic kidney disease (CKD)Objectives: Predictors of chronic kidney disease (CKD) amongst HIV-positive persons are well established, but insights into the prognosis after CKD including the role of modifiable risk factors are limited. Design: Prospective cohort study Methods: D:A:D participants developing CKD (confirmed, >3 months apart, eGFR ≤ 60 mL/min/1.73 m2 or 25% eGFR decrease when eGFR ≤ 60) were followed to incident serious clinical...
Pleural Fluid Cytokine Levels at Baseline and Over Time are Associated With Time to IPC Removal: An Exploratory StudyBackground: The behavior of pleural fluid cytokine (PFCs) levels and their association with pleurodesis after indwelling pleural catheter (IPC) placement is unknown. Objective: A prospective exploratory study was conducted to obtain preliminary data on PFC levels after IPC placement. Methods: The PFC panel consisted of 4 cytokines [interleukin -8 (IL-8), vascular endothelial growth...
The Effect of Web-Based Preoperative and Postoperative Patient Care Education on Nursing Students: A Randomized Controlled StudyThis study examined the effect of Web-based preoperative and postoperative patient care education among undergraduate nursing students. This was an experimental, randomized controlled study. The study included 305 nursing students (experimental group: n = 155, control group: n = 150), who were assessed with the following instruments: the Preoperative and Postoperative Care...
Clinical Findings and Electrodiagnostic Testing in Ulnar Neuropathy at the Elbow and Differences According to Site and Type of Nerve DamageObjective To evaluate the clinical and electrodiagnostic testing (EDX) in ulnar neuropathy at the elbow (UNE) and differences according to site (humeroulnar arcade, HUA, vs. retroepicondylar groove, REG) and injury physiopathology (axonal vs. demyelinating), through prospective multicenter case-control study. Design Cases and controls were matched by age and sex....
Influence of fall environment and fall direction on risk of injury among pre-frail and frail adultsAbstractSummaryIn this prospective study, half of all falls resulted in injury. Pre-frail adults sustained more injuries, while more frail adults had injuries requiring hospitalization or fractures. Pre-frail adults fell more often when in movement compared with frail adults who fell more often when standing and in indoor public spaces.PurposeTo assess prospectively how fall environment and direction...
Is Molecular Diagnosis Necessary for Children with Duchenne Muscular Dystrophy?Theme : NeonatologyNews in BriefAwakening the Spirits and Addressing the Safety Concerns in ChildhoodFlexible Bronchoscopic Removal of Foreign Bodies from Airway of Children: Single Center Experience Over 12 YearsAbstractObjectiveTo report our experience of tracheobronchial foreign body removal in children using flexible bronchoscopy as the primary mode.MethodsHospital records of tracheobronchial foreign body extractions...
Chirurgie secondaire du pavillon de l'oreillePublication date: Available online 3 August 2019Source: Annales de Chirurgie Plastique EsthétiqueAuthor(s): A. MarchacRésuméLa chirurgie secondaire du pavillon de l'oreille peut être divisée en 2 grandes catégories : l'otoplastie secondaire et l'otopoïèse secondaire. Les causes les plus fréquentes d'otoplastie secondaires sont la récurrence du décollement, l'oreille trop recollée, l'oreille désaxée, le lobe décollé, et finalement l'oreille douloureuse....
The Journal of DermatologyVolume 46, Issue 8Pages: 639-741, e267-e307August 2019Issue InformationIssue InformationPages: 639-640 | First Published: 01 August 2019Original Articles Open AccessEfficacy of long‐term treatment with efinaconazole 10% solution in patients with onychomycosis, including severe cases: A multicenter, single‐arm studyKen Iozumi, Masatoshi Abe, Yoshiko Ito, Takashi Uesugi, Takashi Onoduka, Ichiro Kato, Fumihiro Kato, Kazuo Kodama, Hidetoshi Takahashi, Osamu Takeda, Koki Tomizawa, Tomoko...
Journal of Surgical OncologyVolume 120, Issue 3Pages: i-ii, 319-566September 1, 2019COVERCover Image, Volume 120, Number 3, September 1, 2019Kaila Redifer Tremblay, William B. Lea, John C. Neilson, David M. King, Sean M. TuttonPages: i | First Published: 01 August 2019 The outside front cover image is based on the Research Article Percutaneous cryoablation for the treatment of extra‐abdominal desmoid tumors by Kaila Redifer Tremblay et al., https://doi.org/10.1002/jso.25597. Cover design: William...
Association between neutrophil–lymphocyte ratio, socioeconomic status, and ethnic minority with treatment outcome in hepatocellular carcinomaAbstractBackgroundPatients with lower socioeconomic status (SES), ethnic minorities and elevated neutrophil–lymphocyte ratio (NLR) have been suggested to have worse outcomes in hepatocellular carcinoma (HCC). However, how changes in NLR after intervention relate to survival has not been elucidated.ObjectivesWe evaluated the association of NLR with overall survival...
Human-made fires and forest clearance as evidence for late Holocene landscape domestication in the Orinoco Llanos (Venezuela)AbstractIn the Orinoco Llanos, archaeological studies indicate a continuous late Holocene human occupation, including the development of ranked societies, from about 1,500 year bp (ad 500) However, until now palaeoecological studies dealing with the impact of anthropogenic activities in the region have been scarce. Here we present a palynological analysis carried out in the...
Cytomegalovirus-induced pathology in human temporal bones with congenital and acquired infectionAuthor links open overlay panelVladimirTsuprunaNevraKeskinabR.SchleisscPatSchachernaSebahattinCureogluaaDepartment of Otolaryngology-Head and Neck Surgery, University of Minnesota, Minneapolis, MN, USAbDepartment of Veterinary Internal Medicine, Ankara University, Ankara, TurkeycDivision of Pediatric Infectious Disease and Immunology, Department of Pediatrics, University of Minnesota, Minneapolis, MN,...
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Single Sampling Versus Multiple Testing Strategy to Assess Gut Microbiota Composition: Does It Matter?Correction to: Draft Genome Sequence of Cyclohexylamine-Degrading Strain Acinetobacter sp. YT-02 IsolatedThe original version of this article unfortunately contained a mistake in the Fig. S1 of supplementary material. It is corrected with this erratum.Correction to: Anaerobic Degradation of Chloroanilines by Geobacter sp. KT5The original version of this article unfortunately contained a mistake....
Reminder system for adrenaline autoinjectors does not workCorrection to: Air pollutants and primary allergy preventionCorrection to:Allergo J Int 2018https://doi.org/10.1007/s40629-018-0078-7An error was identified in the review on "Air pollutants and primary allergy prevention". The given PM2.5 increment of 2 µg/m3 was wrong and should be replaced with an increment of 5 µg/m3.This was the case on:Page 9, legend …German pollen calendar 4.0: update of the regional pollen calendars 4.0 with measurement...
Control by Viability in a Chemotherapy Cancer ModelAbstractThe aim of this study is to provide a feedback control, called the Chemotherapy Protocol Law, with the purpose to keep the density of tumor cells that are treated by chemotherapy below a "tolerance level" \(L_c\), while retaining the density of normal cells above a "healthy level" \(N_c\). The mathematical model is a controlled dynamical system involving three nonlinear differential equations, based on a Gompertzian law of cell growth. By...
Survey of antiretroviral therapy adherence and predictors of poor adherence among HIV patients in...
Survey of antiretroviral therapy adherence and predictors of poor adherence among HIV patients in a tertiary institution in NigeriaAdekunle Olatayo Adeoti et al.HIV remains a major pandemic that has claimed more than 35 million lives over the last three decades. In 2017, approximately a million HIV related death and 1.8 million newly infected were reported by the World Health Organization with a major burden in sub-Saharan Africa. Adherence is vital to effective antiretroviral therapy (ART) for reducing...
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The Heterogeneous Landscape of Head & Neck Squamous Cell CarcinomasNo abstract availableFinding a Cure for Children With CNS NeuroblastomaNo abstract availableEHR Tool Finds Pediatric Leukemia Patients for Clinical StudiesNo abstract availableIn Search of an Immunotherapy Innovation for Ovarian CancerNo abstract availableChildhood Leukemia Cannot Hide From Immune SystemNo abstract availableUpToDate®No abstract availableEnzalutamide Improved Survival in Metastatic Prostate CancerNo abstract availableOlaparib...
Endoscopic Transgastric Versus Surgical Approach for Infected Necrotizing Pancreatitis: A Systematic Review and Meta-AnalysisSurgical approach (SA) is the standard treatment for infected necrotizing pancreatitis (INP) and endoscopic transgastric approach (ETA) is a promising alternative treatment. This systematic review and meta-analysis aimed to compare the effectiveness and safety of ETA versus SA in INP. Several databases were systematically searched for eligible studies that compared ETA with...
Norfloxacin, ciprofloxacin, trimethoprim–sulfamethoxazole, and rifaximin for the prevention of spontaneous bacterial peritonitis: a network meta-analysisFor the prevention of spontaneous bacterial peritonitis (SBP) in cirrhotic patients with ascites, prophylactic antibiotics are recommended as a standard regimen. This study aimed to assess the efficacy of norfloxacin (N), ciprofloxacin (C), trimethoprim–sulfamethoxazole (T-S), and rifaximin (R) in the prevention of SBP. We searched the electronic...
Sponsorship by Big Oil, Like the Tobacco Industry, Should be Banned by the Research CommunityNo abstract availableFine Particulate Air Pollution and Birthweight: Differences in Associations Along the Birthweight DistributionBackground: Maternal exposure to fine particulate air pollution (PM2.5) during pregnancy is associated with lower newborn birthweight, which is a risk factor for chronic disease. Existing studies typically report the average association related with PM2.5 increase, which does...
Beneficial effect of ticagrelor on microvascular perfusion in patients with ST-segment elevation myocardial infarction undergoing a primary percutaneous coronary interventionBackground Ticagrelor significantly reduced the incidence of death, myocardial infarction, and stent thrombosis in patients with ST-segment elevation myocardial infarction (STEMI) intended for reperfusion with a primary percutaneous coronary intervention (pPCI). However, the effects of this drug on microvascular perfusion in...
Routine cardiac troponin assessment after percutaneous coronary intervention: useful or hype?Although the angiographic and procedural success of percutaneous coronary intervention (PCI) is now very high, some severe complications may still develop, including periprocedural myocardial infarction (MI). An accurate diagnosis of this condition is essential for guiding the clinical management, as these patients may need a tailored management. The current recommendations for diagnosing periprocedural myocardial...
Mark above section as read
The Heterogeneous Landscape of Head & Neck Squamous Cell CarcinomasNo abstract availableFinding a Cure for Children With CNS NeuroblastomaNo abstract availableEHR Tool Finds Pediatric Leukemia Patients for Clinical StudiesNo abstract availableIn Search of an Immunotherapy Innovation for Ovarian CancerNo abstract availableChildhood Leukemia Cannot Hide From Immune SystemNo abstract availableUpToDate®No abstract availableEnzalutamide Improved Survival in Metastatic Prostate CancerNo abstract availableOlaparib...
Endoscopic Transgastric Versus Surgical Approach for Infected Necrotizing Pancreatitis: A Systematic Review and Meta-AnalysisSurgical approach (SA) is the standard treatment for infected necrotizing pancreatitis (INP) and endoscopic transgastric approach (ETA) is a promising alternative treatment. This systematic review and meta-analysis aimed to compare the effectiveness and safety of ETA versus SA in INP. Several databases were systematically searched for eligible studies that compared ETA with...
Norfloxacin, ciprofloxacin, trimethoprim–sulfamethoxazole, and rifaximin for the prevention of spontaneous bacterial peritonitis: a network meta-analysisFor the prevention of spontaneous bacterial peritonitis (SBP) in cirrhotic patients with ascites, prophylactic antibiotics are recommended as a standard regimen. This study aimed to assess the efficacy of norfloxacin (N), ciprofloxacin (C), trimethoprim–sulfamethoxazole (T-S), and rifaximin (R) in the prevention of SBP. We searched the electronic...
Sponsorship by Big Oil, Like the Tobacco Industry, Should be Banned by the Research CommunityNo abstract availableFine Particulate Air Pollution and Birthweight: Differences in Associations Along the Birthweight DistributionBackground: Maternal exposure to fine particulate air pollution (PM2.5) during pregnancy is associated with lower newborn birthweight, which is a risk factor for chronic disease. Existing studies typically report the average association related with PM2.5 increase, which does...
Beneficial effect of ticagrelor on microvascular perfusion in patients with ST-segment elevation myocardial infarction undergoing a primary percutaneous coronary interventionBackground Ticagrelor significantly reduced the incidence of death, myocardial infarction, and stent thrombosis in patients with ST-segment elevation myocardial infarction (STEMI) intended for reperfusion with a primary percutaneous coronary intervention (pPCI). However, the effects of this drug on microvascular perfusion in...
Routine cardiac troponin assessment after percutaneous coronary intervention: useful or hype?Although the angiographic and procedural success of percutaneous coronary intervention (PCI) is now very high, some severe complications may still develop, including periprocedural myocardial infarction (MI). An accurate diagnosis of this condition is essential for guiding the clinical management, as these patients may need a tailored management. The current recommendations for diagnosing periprocedural myocardial...
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