AMEDEO Otorhinolaryngologyhttp://www.amedeo.comhttp://m.amedeo.com2019-10-07Your Personal Amedeo Web PageComputer: http://amedeo.com/summary/px.php?table=orl&cid=386453+Smartphone: http://m.amedeo.com/p12.php?table=orl&cid=3864532. http://OLIENA.comLanguage recovery after stroke3. http://TheWordBrain.comA short guide to fast language learning4. http://FJ4D.com + http://FB4D.com5087 Free Journals + 364 Selected Free BooksBest regards,Bernd Sebastian Kampshttp://linkedin.com/in/bskamps________________...
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Medicine by Alexandros G. SfakianakisCorrelation of tumor burden in sentinel lymph nodes with tumor burden in non-sentinel lymph nodes and survival in cutaneous melanoma.Correlation of tumor burden in sentinel lymph nodes with tumor burden in non-sentinel lymph nodes and survival in cutaneous melanoma.: CONCLUSIONS: In patients with CM who undergo CLND, SLN tumor burden predicts non-SLN tumor burden. SLN tumor burden parameters provide accurate prognostic stratification independent of non-SLN status...
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Cancers, Vol. 11, Pages 1497: Comprehensive Metabolomic Search for Biomarkers to Differentiate Early Stage Hepatocellular Carcinoma from CirrhosisCancers, Vol. 11, Pages 1497: Comprehensive Metabolomic Search for Biomarkers to Differentiate Early Stage Hepatocellular Carcinoma from Cirrhosis Cancers doi: 10.3390/cancers11101497 Authors: Kim Cho Yu Jang Yoon Park Cho The established biomarker for hepatocellular carcinoma (HCC), serum α-fetoprotein (AFP), has suboptimal performance in early disease...
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Higher frequency of hospitalization but lower relative mortality for pandemic influenza in people with type 2 diabetes: AbstractBackgroundThere is limited evidence linking type 2 diabetes (T2D) to influenza‐related complications.ObjectivesTo test a set of research questions relating to pandemic influenza vaccination, hospitalization and mortality in people with and without T2D.MethodsIn this population‐based cohort study, we linked individual‐level data from several national registers for all Norwegian...
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Rhinosinusitis in Pediatric Primary Ciliary Dyskinesia: Impact of Disease: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectivesPrimary ciliary dyskinesia (PCD) is a genetic disorder characterized by abnormal respiratory cilia ultrastructure and/or function causing defective mucociliary clearance. We investigated the extent and severity of rhinosinusitis in a large cohort of children with PCD and explored associations among risk factors, including genotype and sinus disease.Study DesignRetrospective...
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Submental Island Flap versus Free Flap Reconstruction for Complex Head and Neck Defects: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveComplex soft tissue reconstruction of the head and neck requires a viable, versatile, and dependable flap. Free flaps, such as the radial forearm and anterolateral thigh flap, have been the mainstay of complex head and neck reconstruction. However, a local pedicled flap, such as the submental island flap (SIF), could be a more effective and less demanding...
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Syndrome society: Stop normalising mental illness and labelling children as disordered, says top psychologist - HeraldScotland: Syndrome society: Stop normalising mental illness and labelling children as disordered, says top psychologist HeraldScotland
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Antimicrobial activity of a novel polyherbal combination for the treatment of vaginal infection: Shiv Kumar Yadav, Gaurav K Jain, Avijit Mazumder, Roop K KharJournal of Advanced Pharmaceutical Technology & Research 2019 10(4):190-194The present study evaluated the antimicrobial activity of Azadirachta indica (AI), Cichorium intybus (CI), and Trigonella foenum-graecum (TFG) against bacterial and fungal pathogens responsible for the vaginal infections. The AI, CI, and TFG were selected to include...
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Correlation of tumor burden in sentinel lymph nodes with tumor burden in non-sentinel lymph nodes and survival in cutaneous melanoma.: CONCLUSIONS: In patients with CM who undergo CLND, SLN tumor burden predicts non-SLN tumor burden. SLN tumor burden parameters provide accurate prognostic stratification independent of non-SLN status and should be considered for incorporation into future staging systems and integrated risk models. PMID: 31570567 [PubMed - as supplied by publisher] (Source: Clinical...
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PET/CT-guided biopsy with respiratory motion correction: AbstractPurposeGiven the ability of positron emission tomography (PET) imaging to localize malignancies in heterogeneous tumors and tumors that lack an X-ray computed tomography (CT) correlate, combined PET/CT-guided biopsy may improve the diagnostic yield of biopsies. However, PET and CT images are naturally susceptible to problems due to respiratory motion, leading to imprecise tumor localization and shape distortion. To facilitate PET/CT-guided...
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Touchless scanner control to support MRI-guided interventions: AbstractPurposeMRI-guided interventions allow minimally invasive, radiation-free treatment but rely on real-time image data and free slice positioning. Interventional interaction with the data and the MRI scanner is cumbersome due to the diagnostic focus of current systems, confined space and sterile conditions.MethodsWe present a touchless, hand-gesture-based interaction concept to control functions of the MRI scanner typically used...
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Evolutionary processes of melanomas from giant congenital melanocytic nevi: AbstractMelanoma can develop in a congenital melanocytic nevus (CMN). In fact, a large CMN is associated with a high risk of developing melanoma. Although melanomas arising from CMNs are thought to have a pathogenesis distinct from conventional melanomas, no studies have been conducted on the evolution or tumor heterogeneity of CMN melanomas. We applied multi‐region whole‐exome sequencing to investigate the clonal nature...
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Combined ipilimumab and nivolumab first‐line and after BRAF targeted therapy in advanced melanoma: AbstractCombination ipilimumab and nivolumab is a highly active systemic therapy for metastatic melanoma but can cause significant toxicity. We explore the safety and efficacy of this treatment in routine clinical practice, particularly in the setting of BRAF targeted therapy.Consecutive patients with unresectable stage IIIC/IV melanoma commenced on ipilimumab and nivolumab across 10 tertiary melanoma...
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Landscapes, environments and societies: The development of culture in Lower Palaeolithic Europe: Publication date: December 2019Source: Journal of Anthropological Archaeology, Volume 56Author(s): Rob Davis, Nick AshtonAbstractIdentification of cultural groups is rare in the early Palaeolithic due to site formation processes including taphonomy and the effect of raw material and site function. This paper reviews a critical period in Europe at about 400 ka (MIS 11) when we may be able to identify such...
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Evaluation of breast carcinoma regression after preoperative chemotherapy by label‐free multiphoton imaging and image analysis: AbstractNeoadjuvant chemotherapy is increasingly being used in breast carcinoma as it significantly improves the prognosis and consistently leads to an increased rate of breast preservation. How to accurately assess tumor response after treatment is a crucial factor for developing reasonable therapeutic strategy. In this study, we were in an attempt to monitor tumor response...
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Autofluorescence Excitation‐Emission Matrices (EEMs) as a quantitative tool for the assessment of meat quality: AbstractCommercially produced meat is currently graded by a complex and partly subjective multiparameter methodology; a quantitative method of grading, using small samples would be desirable. Here, we investigate the correlation between commercial grades of beef and spectral signatures of native fluorophores in such small samples. Beef samples of different commercial grades were characterized...
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Distinguishing bowenoid papulosis from Bowen disease in the mouth: a case report: AbstractBowenoid papulosis (BPap) is a rare skin disorder linked to human papillomavirus (HPV) infection and characterized clinically by the presence of scattered papules or small plaques, multiple and pigmented, that involve the stratified squamous epithelium. Only 13 cases have been reported in the medical literature. Bowen disease (BD) is recognized as the main differential diagnosis of BPap. An 80‐year old white...
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White sponge nevus: A condition not always clinically suspected: ABSTRACTWhite sponge nevus (WSN) is an uncommon benign inherited disorder characterized by white and diffuse painless lesions in oral, esophageal, or genital mucosa. The lesions may develop at birth or later in childhood or adolescence, with careful clinical examination being sufficient for diagnosis in most cases. However, microscopic analysis may be necessary particularly in adults in which other whitish oral lesions may be clinically...
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Metastatic Pancreatic Adenosquamous Carcinoma to the Scalp: A Case Report and Review of the Literature: AbstractMetastatic carcinoma to the skin occurs in only a minority of patients with a visceral or internal malignancy, with breast, lung and colorectum accounting for the majority of cases. We present the case of a 66‐year‐old man with a recent violaceous nodule of the left scalp (1.2 x 1.0 x 0.2 cm) that was a metastatic pancreatic adenosquamous carcinoma, representing a seemingly rare event....
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Café noir spots: A Feature of Familial Progressive Hyper‐ and Hypopigmentation: AbstractFamilial progressive hyper‐ and hypopigmentation (FPHH) is a rare genodermatosis characterized by multiple café au lait spots and hypopigmented ash‐leaf macules intermingled with blotchy hyperpigmentation (1,2). Herein, we describe a Turkish FPHH patient with café‐noir spots.A 16‐year‐old male presented to our Pediatric Dermatology Clinic, with extensive hyperpigmentation, irregular brown patches, and hypopigmented...
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Cross‐reactivity in beta‐lactams after a non‐immediate cutaneous adverse reaction: experience of a reference center for toxic bullous diseases and severe cutaneous adverse reactions: AbstractBackgroundCross‐reactivity among beta‐lactam antibiotics (BL) is essentially reported in immediate hypersensitivity.ObjectivesTo evaluate cross‐reactivity beyond BLs in patients with non‐immediate cutaneous adverse drug reaction (non‐immediate CADR) managed in a dermatology reference center of toxic bullous and...
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Identification of CD49a+ CD8+ resident memory T cells in vitiligo‐like lesions associated with nivolumab treatment for melanoma: AbstractImmune checkpoint inhibitor (ICI) has brought major therapeutic advances in melanoma care, but ICI can cause unique side effects, often termed immune‐related adverse events (irAEs), such as skin rash, vitiligo, colitis, and pneumonitis. Several recent studies revealed a correlation between occurrence of vitiligo‐like lesions and clinical responses in advanced melanoma...
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Associated primary tumors in patients with primary cutaneous lymphoma: a single center retrospective cohort study: AbstractPrimary cutaneous lymphomas (CL) are the second most common group of extranodal non‐Hodgkin lymphomas (NHL). Cutaneous T‐cell lymphomas (CTCL) account for the majority of cases.1 Many patients with CL have a rather good prognosis and for those the impact on outcome, if an associated primary neoplasm occurs, is even more critical than in the patients with aggressive CL subtypes....
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Amino acid charge and epidermolysis bullosa simplex severity: Genotype‐phenotype correlations: AbstractEpidermolysis bullosa simplex (EBS) is a genetic skin disorder characterized by mechanical fragility and blistering of the skin. Localized EBS (EBS‐loc: OMIM 131800) is the mildest variant, with blistering occurring only in the hands and feet. EBS is mainly caused by autosomal dominant mutations in the KRT5 or KRT14 gene, encoding keratin 5 (K5) or keratin 14 (K14), respectively. Here, we report...
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Use of topical calcipotriol for identification of patients with psoriasis in administrative healthcare data – a validation study: AbstractCalcipotriol has been used to treat psoriasis for more than three decades. Previous interview data of 44 Danish dermatologists and 93 general practitioners have indicated that calcipotriol (alone or combined with topical corticosteroids [TCS]) was the most commonly used treatment for newly diagnosed psoriasis patients (48‐54%) and that this was used in 71% of patients...
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Isotretinoin and risk factors for suicide attempt: a population‐based comprehensive case series and nested case‐control study using 2010‐2014 French Health Insurance Data: AbstractBackgroundAlthough the causal role of isotretinoin in suicidal behaviour is controversial, suicide attempts (SA) do occur among patients taking isotretinoin.ObjectivesTo describe patient profiles and the management of isotretinoin among patients who committed or attempted suicide under treatment. To assess the risk factors...
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Neonatal and Self‐healing Linear immunoglobulin A dermatosis: AbstractLinear immunoglobulin A dermatosis (LAD) is an autoimmune bullous dermatosis commonly reported in children over the age of 5. It is characterized by clear vesicles and blisters, arranged in a "crown of jewels" annular shape, on a normal or erythematous skin. Its common locations are the trunk, the limbs, the perineum and perioral areas. So far, 9 neonatal LAD have been reported.
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MRI safety and devices: An update and expert consensus: The use of magnetic resonance imaging (MRI) is increasing globally, and MRI safety issues regarding medical devices, which are constantly being developed or upgraded, represent an ongoing challenge for MRI personnel. To assist the MRI community, a panel of 10 radiologists with expertise in MRI safety from nine high‐volume academic centers formed, with the objective of providing clarity on some of the MRI safety issues for the 10 most frequently...
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Prediction of biochemical recurrence in prostate cancer patients who underwent prostatectomy using routine clinical prostate multiparametric MRI and decipher genomic score: BackgroundBiochemical recurrence (BCR) affects a significant proportion of patients who undergo robotic‐assisted laparoscopic prostatectomy (RALP).PurposeTo evaluate the performance of a routine clinical prostate multiparametric magnetic resonance imaging (mpMRI) and Decipher genomic classifier score for prediction of biochemical...
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Assessment of the Hemodynamics of Autogenous Arteriovenous Fistulas With 4D Phase Contrast‐Based Flow Quantification MRI in Dialysis Patients: BackgroundRegular monitoring of autogenous arteriovenous fistulas (AVFs) for hemodialysis patients has importance. Hence, 4D flow MRI may be an alternative for assessing the hemodynamics of AVFs.PurposeTo compare the hemodynamics of AVFs using Doppler ultrasound (DUS) and 4D‐MRI in renal dialysis patients.Study TypeCase–control study from October 2017 to April...
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Maxillary central incisor gingival papilla and zenith heights with and without periodontally accelerated osteogenic orthodontics: View/Download PDF Download ---Citations---BibTeXRISOriginal Research9 (3); 172-177 doi:10.25259/APOS_74_2019 Maxillary central incisor gingival papilla and zenith heights with and without periodontally accelerated osteogenic orthodonticsMariam Alzaabi1, Donald J. Ferguson2, Laith Makki2, M. Thomas Wilcko31Private Practice in Orthodontics, Abu Dhabi, UAE,...
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Effectiveness of low binding frictional materials: Evaluation of the binding frictional resistance of improved superelastic nickel-titanium alloy wires with different bracket combinations: View/Download PDF Download ---Citations---BibTeXRISOriginal Research9 (3); 156-164 doi:10.25259/APOS_25_2019 Effectiveness of low binding frictional materials: Evaluation of the binding frictional resistance of improved superelastic nickel-titanium alloy wires with different bracket combinationsYoshio...
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Foods, Vol. 8, Pages 456: Comparison of Phytochemicals, Antioxidant and Anti-Inflammatory Properties of Sun-, Oven- and Freeze-Dried Ginger Extracts Foods doi: 10.3390/foods8100456 Authors: Iswaibah Mustafa Nyuk Ling Chin Sharida Fakurazi Arulselvan Palanisamy The effects of different drying methods, including sun-, oven-, and freeze-drying on the changes in the antioxidant and anti-inflammatory activities of ginger (Zingiber officinale var. Rubra) rhizome were studied. Sun-,...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,Real‐world experiences of apremilast in clinics for Japanese patients with psoriasis: AbstractPsoriasis, though not an immediately life‐threatening disorder, still lowers quality of life and disrupts daily functions. While many treatments for psoriasis exist, few are convenient and safe long term; even if sufficiently effective, treatments themselves often decrease quality of life and make long‐term treatment adherence difficult. Approved in Japan in December 2016, apremilast was expected to function...
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Prevalence of atopy and staphylococcal superantigen‐specific immunoglobulin E (IgE) antibodies and total serum IgE in primary cutaneous T‐ and B‐cell lymphoma: AbstractThe prevalence of atopy was investigated in 20 patients with Sézary syndrome (SS), 20 patients with plaque phase mycosis fungoides (MF), 9 patients with primary cutaneous marginal zone lymphoma (pcMZL) and 8 patients with primary cutaneous follicle center lymphoma (pcFCL) with the Phadiatop multi‐allergen test. The relationship among...
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Potassium iodide in successful treatment of erythema nodosum‐like lesions induced by combination therapy with dabrafenib and trametinib:
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Er:YAG Laser versus Sharp Debridement in Management of Chronic Wounds: Effects on Pain and Bacterial Load: AbstractChronic wounds affect roughly 6.5 million patients in the United States annually. Current standard of therapy entails weekly sharp debridement. However, the sharp technique is associated with significant pain, while having minimal impact on the bioburden. Our study proposes the Er:YAG laser as an alternative method of debridement that may decrease procedural pain, reduce bioburden, and...
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Imiquimod to prevent keloid recurrence post excision: A systematic review and meta‐analysis: AbstractImiquimod 5% cream, an immune response modifier capable of inducing IFN‐α, TNF‐α and interleukins 1, 6 and 8. It was approved for use in the management of genital and perianal warts and soon embraced as a method to diminish the recurrence of keloids post excision. A previous meta‐analysis included four studies. This meta‐analysis is part of a larger systematic review project on the effect of moisturisers...
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IJMS, Vol. 20, Pages 4940: The Regulatory Role of MicroRNAs in Breast Cancer: IJMS, Vol. 20, Pages 4940: The Regulatory Role of MicroRNAs in Breast CancerInternational Journal of Molecular Sciences doi: 10.3390/ijms20194940Authors: Hui-Yi Loh Brendan P. Norman Kok-Song Lai Nik Mohd Afizan Nik Abd. Rahman Noorjahan Banu Mohamed Alitheen Mohd Azuraidi Osman MicroRNAs (miRNAs) are small non-coding RNA molecules which function as critical post-transcriptional gene regulators of various biological...
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Atypical radiological presentation of multiple cystic brain metastases from lung cancer simulating neurocysticercosis: Brain metastases (BMs) are usually characterised by vasogenic oedema and mass effect, but cystic appearance can rarely occur, mimicking parasitosis, such as neurocysticercosis (NCC). A woman in her mid-50s was admitted for dizziness and upper left extremity paresis. Neuroimaging showed multiple cystic lesions consistent with multiple stages of NCC evolution, and empiric albendazole...
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Acute psychosis and concurrent rhabdomyolysis unveiling diagnosis of hypothyroidism: Neuropsychiatric and muscular symptoms can develop as part of hypothyroidism. However, frank psychosis or rhabdomyolysis due to hypothyroidism are uncommon and have been reported rarely as the first presenting features of hypothyroidism. We report a case of a 44-year-old man who presented with a 2-week history of delusions, hallucinations and mild bilateral leg pain, without apparent signs of myxedema. Investigations...
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Coexistence of myasthenia gravis with hypokalemic periodic paralysis: a rare presentation: Bilateral symmetrical weakness of acute onset is not very uncommon and the differential varies widely from life-threatening neurological illnesses to metabolic and electrolyte derangements. We report the case of a young female with severe muscle weakness, respiratory distress and hypokalemia who required immediate intubation on arrival to emergency department. During hospital course, even after normalisation...
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Novel missense mutation in the ATP1A2 gene associated with atypical sporapedic hemiplegic migraine: Hemiplegic migraine (HM) is a rare subtype of migraine with aura in which attacks include transient motor weakness or hemiparesis that can last several days. HM is linked to mutations in three different genes, CACNA1A, ATP1A2 and SCN1A, which encode for ion transporters. The clinical spectrum includes atypical symptoms such as impaired consciousness, epileptic seizures, permanent cerebellar ataxia...
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B cell acute lymphoblastic leukaemia presenting with isolated soft tissue tumours: the non-myeloid sarcoma: Soft tissue leukaemic masses are a well-described clinical feature of myeloid haematological neoplasms. In paediatric acute lymphoblastic leukaemia (ALL), such soft tissue leukaemic sarcomas have not been reported as a presenting feature. Here we report a 3-year-old boy with ALL who presented to us with isolated soft tissue swellings for a duration of 9 months. The significance of these 'non-myeloid'...
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Iatrogenic pneumothorax following vigorous suctioning of mucus plug during flexible bronchoscopy: Flexible bronchoscopy is a commonly performed procedure in pulmonary medicine. The common complications following bronchoscopy include minor bleeding, transient hypoxaemia, pneumothorax and others. Pneumothorax during diagnostic flexible bronchoscopy is mainly encountered after performing transbronchial lung biopsy. Iatrogenic pneumothorax is uncommon when lung biopsy is not performed. Herein, we report...
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Small bowel diaphragm disease from long-term non-steroidal anti-inflammatory use: Small bowel diaphragm disease (SBDD) is characterised by circumferential lesions of short length (<5 mm), causing intrinsic stenosis of the small bowel lumen. A 63-year-old women with a history of long-term non-steroidal anti-inflammatory use, presented with a 12-month history of intermittent episodes of colicky abdominal pain, nausea and vomiting. Her only past surgery was a laparoscopic hysterectomy. Abdominal...
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Change in paradigm: impact of an IBD medical home on the outpatient management of acute severe ulcerative colitis: A 72-year-old man presents with acute severe ulcerative colitis (ASUC), initially partially responsive to intravenous steroids and infliximab over a 3-day hospital stay. Following discharge and over the course of 15 days, his care was coordinated by the inflammatory bowel disease medical home team, who conducted clinical laboratory assessments and two outpatient flexible sigmoidoscopies...
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Positive molecular breast imaging: challenges and problem solving with contrast-enhanced spectral mammography: Molecular breast imaging (MBI) is a relatively new technique with high sensitivity for breast cancer detection. However, because it only provides limited anatomical information, cross-correlation of MBI findings with conventional breast imaging modalities such as full field digital mammography can be challenging. We report a case of a positive MBI study in a supplemental screening setting,...
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Rapid visual recovery following intravenous tocilizumab in glucocorticoid resistant refractory giant cell arteritis: A 72-year-old man presented with a short history of headache, jaw claudication, double vision, amaurosis fugax and distended temporal arteries. A diagnosis of giant cell arteritis (GCA) was confirmed on temporal artery ultrasound and temporal artery biopsy. Despite treatment with high-dose oral glucocorticoid (GC) and multiple pulses of intravenous methylprednisolone, his vision deteriorated...
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Abscess formation following hydrogel spacer for prostate cancer radiotherapy: a rare complication: Periprostatic abscess is a rare complication of hydrogel spacers in radiotherapy for prostate cancer. We present the case of a 61-year-old man who developed this condition. Abdominopelvis CT scan revealed a 54x35x75 mm collection in the location of the SpaceOAR, for which ultrasound-guided transperineal percutaneous drainage of the periprostatic abscess was performed. The patient remains well with serial...
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<strong>YJBMT1523.</strong> An adapted dance program for children with Charcot-Marie-Tooth disease: an exploratory study: Publication date: Available online 4 October 2019Source: Journal of Bodywork and Movement TherapiesAuthor(s): Claire CHERRIERE, Melissa MARTEL, Sylvie FORTIN, Marie-Joanie RAYMOND, Louis Nicolas VEILLEUX, Martin LEMAYAbstractBackgroundCharcot-Marie-Tooth disease (CMT) is a rare hereditary peripheral neuropathy. Its sensorimotor clinical manifestations are heterogeneous,...
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Changes Over Time in the Electrically Evoked Compound Action Potential (ECAP) Interphase Gap (IPG) Effect following Cochlear Implantation in Guinea Pigs: Publication date: Available online 4 October 2019Source: Hearing ResearchAuthor(s): Kara C. Schvartz-Leyzac, Deborah J. Colesa, Christopher J. Buswinka, Donald L. Swiderski, Yehoash Raphael, Bryan E. PfingstAbstractThe electrically-evoked compound action potential (ECAP) is correlated with spiral ganglion neuron (SGN) density in cochlear implanted...
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Cortical auditory responses index the contributions of different RMS-level-dependent segments to speech intelligibility: Publication date: Available online 4 October 2019Source: Hearing ResearchAuthor(s): Lei Wang, Hua Li, Ed X. Wu, Fei ChenAbstractPrevious behavioral and neurophysiological studies indicated that the use of an appropriate segmentation method to parse speech streams into meaningful chunks is of vital importance for the examination of sentence perception and intelligibility. Researchers...
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Association between mandibular advancement device therapy and reduction of excessive daytime sleepiness due to obstructive sleep apnoea: SummaryBackgroundExcessive daytime sleepiness (EDS) is frequently reported as a symptom for obstructive sleep apnoea (OSA), leading to problems with concentration, mood and memory. Mandibular advance device (MAD) is considered as an effective therapy to control OSA, reducing EDS and improving sleep quality.ObjectivesThe present study aimed to investigate the effects...
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Auditory streaming and bistability paradigm extended to a dynamic environment: Publication date: Available online 5 October 2019Source: Hearing ResearchAuthor(s): Áine Byrne, John Rinzel, James RankinAbstractWe explore stream segregation with temporally modulated acoustic features using behavioral experiments and modeling. The auditory streaming paradigm in which alternating high- A and low-frequency tones B appear in a repeating ABA- pattern, has been shown to be perceptually bistable for extended...
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Autoimmune Polyglandular Diseases: Publication date: Available online 4 October 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): George J. Kahaly, Lara FrommerAbstractAutoimmune polyglandular diseases (APD) are defined as the presence of two autoimmune –induced endocrine failures. With respect to the significant morbidity and potential mortality of APD, the diagnostic objective is to detect APD at an early stage, with the advantage of less frequent complications,...
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Subcutaneous Injection of Drugs: Literature Review of Factors Influencing Pain Sensation at the Injection Site: AbstractThe subcutaneous administration route is widely used to administer different types of drugs given its high bioavailability and rapid onset of action. However, the sensation of pain at the injection site might reduce patient adherence. Apart from a direct effect of the drug itself, several factors can influence the sensation of pain: needle features, injection site, volume injected,...
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Quality of life of children with hearing loss in special and mainstream education: a longitudinal studyTirza F.K. van der Straaten, Carolien Rieffe, Wim Soede, Anouk P. Netten, ... Johan H.M. FrijnsIn Press, Journal Pre-proof, Available online 5 October 2019https://www.sciencedirect.com/journal/international-journal-of-pediatric-otorhinolaryngology/articles-in-pressAbstractObjectivesTo compare the quality of life (QoL) of children with hearing loss (HL) and children with normal hearing (NH) and to...
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Designing a mandibular advancement device with topology optimization for a partially edentulous patient: Publication date: Available online 4 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Si-Myung Park, Soyeon Park, Sangkyun Shin, Hyeonjong Lee, Su-Jin Ahn, Laehyun Kim, Soo-Hong Lee, Gunwoo NohAbstractStatement of problemPatients with partial tooth loss treated with implant-supported fixed partial dentures (FPDs) have difficulty using conventional mandibular advancement devices...
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Three dimensionally printed surgical guides for removing fixation screws from onlay bone grafts in flapless implant surgeries: Publication date: Available online 4 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Otavio Henrique Pinhata-Baptista, Roger Nascimento Gonçalves, Ivan Onone Gialain, Marcelo Gusmão Paraíso Cavalcanti, Ricardo Yudi Tateno, Arthur Rodriguez Gonzalez CortesAbstractThe present technique report describes a digital workflow for flapless implant surgery after...
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Prediction of learning curves of 2 dental CAD software programs, part 2: Differences in learning effects by type of dental personnel: Publication date: Available online 4 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): KeunBaDa Son, Kyu-Bok LeeAbstractStatement of problemDental computer-aided design (CAD) software programs are essential elements of the digital workflow. Therefore, it is necessary to study the learning effect of dental CAD software programs for efficient use.PurposeThe...
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Application of the functionally generated path technique in designing an implant-supported fixed prosthesis with CAD-CAM technology: A dental technique: Publication date: Available online 4 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Seong-gi Park, Manyong Kim, Jin-joo Yoo, Joon-Ho YoonAbstractA method involving the digital application of the functionally generated path (FGP) technique to fabricate an implant-supported fixed prosthesis is described. It uses an intraoral optical...
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An analysis of anterior mandibular anatomy by using cone beam computed tomography: A study of 225 mandibular images: Publication date: Available online 4 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Roberta A. Wright, Avinash S. Bidra, Chia-Ling KuoAbstractStatement of problemThe anterior mandible has conventionally been deemed as a safe zone for dental implants. However, with the evolution of cone beam computed tomography (CBCT), several anatomic challenges have been identified...
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Effects of abutment screw preload in two implant connection systems: A 3D finite element study: Publication date: Available online 4 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Won-kyung Jung, Won-sup Lee, Ho-Beom KwonAbstractStatement of problemFinite element analysis (FEA) has been used to evaluate the biomechanical behaviors of dental implants. However, in some FEA studies, the influence of the preload condition has been omitted to simplify the analysis. This might affect...
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Incorporating a facial scanner into the digital workflow: A dental technique: Publication date: Available online 4 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Stefano Granata, Lorenzo Giberti, Paolo Vigolo, Edoardo Stellini, Adolfo Di FioreAbstractThe transfer of extraoral and intraoral clinical information into the virtual environment is necessary to optimize prosthetic treatment planning. The purpose of this article was to describe a digital workflow designed to superimpose...
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Validation of a method of quantifying 3D leakage in dental restorations: Publication date: Available online 4 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Fabio A.P. Rizzante, Rana A.F. Sedky, Adilson Y. Furuse, Sorin Teich, Sérgio K. Ishikiriama, Gustavo MendonçaAbstractStatement of problemA reliable and validated protocol for nondestructive analysis of the entire restorative interface that could be applicable in studies assessing the adaptation of direct and indirect restorations...
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Functionally suitable digital removable complete dentures: A dental technique: Publication date: Available online 4 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Kehui Deng, Yong Wang, Yongsheng Zhou, Yuchun SunAbstractThis article describes a technique for fabricating removable complete dentures by using digital technology which aims to produce an individually designed, diagnostic, complete denture. This technology could reduce the number of appointments compared with traditional...
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A workflow for fabricating a hollow obturator by using 3D digital technologies: Publication date: Available online 4 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Shigeto Koyama, Hiroaki Kato, Takayuki Harata, Keiichi SasakiAbstractConventional methods used for fabricating hollow obturator prostheses have numerous problems. The workflow presented in this article integrates 3D digital technologies into a functional protocol, enabling the fabrication of single-piece hollow prostheses...
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Diagnosis and Management of Immune Related Adverse Events (irAEs) in Cancer Immunotherapy: Publication date: Available online 4 October 2019Source: Biomedicine & PharmacotherapyAuthor(s): Yi-He Liu, Xin-Yuan Zang, Jin-Cheng Wang, Shan-Shan Huang, Jiang Xu, Peng ZhangAbstractImmune checkpoint inhibitors (ICPIs) and chimeric antigen receptor (CAR) T-cell therapy are two main promising methods of immunotherapy, which have become increasingly important in cancer treatment. After the wider application...
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Rehmannioside A attenuates cognitive deficits in rats with vascular dementia (VD) through suppressing oxidative stress, inflammation and apoptosis: Publication date: December 2019Source: Biomedicine & Pharmacotherapy, Volume 120Author(s): Miao Sun, Xiaoming Shen, Yunzhi MaAbstractVascular dementia (VD) is a degenerative cerebrovascular disorder, leading to progressive decline of cognitive abilities and memory. Rehmannioside A (ReA) is isolated from Rehmanniae Radix, which exhibits protective...
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Nr2e1 ablation impairs liver glucolipid metabolism and induces inflammation, high-fat diets amplify the damage: Publication date: December 2019Source: Biomedicine & Pharmacotherapy, Volume 120Author(s): Qing Xiong, Yuwen Wu, Miao Yang, Guijun Wu, Ye Wang, Huawei Wang, Jieyuan Feng, Linyang Song, Beier Tong, Guangzhen He, Yancheng XuAbstractNonalcoholic fatty liver disease (NAFLD) is a common and complex metabolic disorder. Despite the widespread concern, there are still few effective treatments...
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LINC01234 facilitates growth and invasiveness of oral squamous cell carcinoma through regulating the miR-637/NUPR1 axis: Publication date: December 2019Source: Biomedicine & Pharmacotherapy, Volume 120Author(s): Wenjie Huang, Jia Cao, Xuxia PengAbstractLINC01234 plays a pivot role in the tumorigenesis of gastric cancer, colon cancer and lung cancer. However, how LINC01234 participates in oral squamous cell carcinoma (OSCC) progression remains unknown. In our research, we showed that LINC01234...
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Microbial Profile in Tracheostomy Tube and Tracheostoma: A Prospective Study: AbstractTracheostomy a lifesaving procedure done more frequently for critically ill patients for mechanical ventilation, bronchopulmonary toileting, reduce pulmonary effort has variable complications to itself. The common being secondary infection with bacteria and fungi, which in turn lead to granulation formation in stoma and on peristomal region. This prospective study was done with an aim to study, correlate and compare...
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The Quasi-uniform assumption for Spinal Cord Stimulation translational research: Publication date: Available online 4 October 2019Source: Journal of Neuroscience MethodsAuthor(s): Niranjan Khadka, Dennis Q. Truong, Preston Williams, John H. Martin, Marom BiksonAbstractBackgroundQuasi-uniform assumption is a general theory that postulates local electric field predicts neuronal activation. Computational current flow model of spinal cord stimulation (SCS) of humans and animal models inform how the quasi-uniform...
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Phenotypical characterization of tree nuts and peanut allergies in east Mediterranean children: Publication date: Available online 4 October 2019Source: Allergologia et ImmunopathologiaAuthor(s): Pınar Gur Cetinkaya, Betul Buyuktiryaki, Ozge Soyer, Umit Murat Sahiner, Cansın Sackesen, Bulent Enis SekerelAbstractIntroduction/ObjectivesThe characteristics of tree nuts (TNs) and peanut (PN) allergies vary in different regions of the world. We aim to identify the characteristics of TNs/PN allergies in...
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Emerging Trends of Zygomaticomaxillary Complex Fractures and Their Etiological Analysis in a Tertiary Health Centre from Eastern India: A Retrospective Study: AbstractIntroductionMaxillofacial region is one of the most complicated arrangements of bony and soft tissues in human body, superiorly bounded by cranial bones and inferiorly by the mandible with interposed dentition. This is one of the reasons which make injuries to this region difficult to manage and often controversial. The severity and...
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Feasibility of repeat transradial access for neuroendovascular procedures: IntroductionTransradial artery access (TRA) for cerebrovascular angiography is increasing due to decreased access site complications and overwhelming patient preference. While interventional cardiologists have reported up to 10 successive TRA procedures via the same radial access site, this is the first study examining successive use of the same artery for repeat procedures in neurointerventional procedures.1MethodsWe reviewed...
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Second IVIg course in Guillain-Barre syndrome with poor prognosis: the non-randomised ISID study: ObjectiveTo compare disease course in patients with Guillain-Barré syndrome (GBS) with a poor prognosis who were treated with one or with two intravenous immunoglobulin (IVIg) courses.MethodsFrom the International GBS Outcome Study, we selected patients whose modified Erasmus GBS Outcome Score at week 1 predicted a poor prognosis. We compared those treated with one IVIg course to those treated with two...
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Gut microbiota shape 'inflamm-ageing cytokines and account for age-dependent decline in DNA damage repair: ObjectiveFailing to properly repair damaged DNA drives the ageing process. Furthermore, age-related inflammation contributes to the manifestation of ageing. Recently, we demonstrated that the efficiency of repair of diethylnitrosamine (DEN)-induced double-strand breaks (DSBs) rapidly declines with age. We therefore hypothesised that with age, the decline in DNA damage repair stems from age-related...
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Cancers, Vol. 11, Pages 1497: Comprehensive Metabolomic Search for Biomarkers to Differentiate Early Stage Hepatocellular Carcinoma from Cirrhosis: Cancers, Vol. 11, Pages 1497: Comprehensive Metabolomic Search for Biomarkers to Differentiate Early Stage Hepatocellular Carcinoma from CirrhosisCancers doi: 10.3390/cancers11101497Authors: Kim Cho Yu Jang Yoon Park Cho The established biomarker for hepatocellular carcinoma (HCC), serum α-fetoprotein (AFP), has suboptimal performance...
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Personalised Warfarin Dosing in Children Post-cardiac Surgery: AbstractWarfarin dosing is challenging due to a multitude of factors affecting its pharmacokinetics (PK) and pharmacodynamics (PD). A novel personalised dosing algorithm predicated on a warfarin PK/PD model and incorporating CYP2C9 and VKORC1 genotype information has been developed for children. The present prospective, observational study aimed to compare the model with conventional weight-based dosing. The study involved two groups...
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Retrospective study on bevacizumab in the treatment of non-small cell lung cancer with brain metastases: AbstractBackgroundBevacizumab was demonstrated to have efficacy in patients with non-small cell lung cancer (NSCLC) and brain metastases. However, cerebral toxicities were a major concern. This study aims to investigate the efficacy and risk factors of toxicity of bevacizumab in brain metastases.MethodsAll patients with advanced NSCLC hospitalized in our institute were screened and only those,...
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Effects of bazedoxifene and low-intensity aerobic exercise on bone and fat parameters in ovariectomized rats: AbstractIntroductionPostmenopausal osteoporosis and dyslipidemia are well-known skeletal and metabolic changes in middle-aged women. We investigated the effects of combined treatments with a selective estrogen receptor modulator (SERM) and exercise on bone and fat parameters in ovariectomized (OVX) rats.Materials and MethodsSixteen-week-old female Sprague–Dawley rats underwent bilateral ovariectomy,...
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The 24‐hour, 28‐day and 7‐day post moisturizing efficacy of ceramides 1, 3, 6‐II containing moisturizing cream compared with hydrophilic cream on skin dryness and barrier disruption in senile xerosis treatment: AbstractDirect replacement of decreased ceramides in the stratum corneum can be efficacious for skin hydration, skin barrier function, and skin pH. Our study aimed to evaluate the 24‐hour, 28‐day, and 7‐day post‐moisturizing efficacy of ceramide‐containing moisturizer in senile xerosis treatment....
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Defining the Characteristics of Chronic Hypoparathyroidism Not Adequately Controlled on Conventional Therapy: Consensus Findings of Three European Delphi Panels: AbstractIntroductionEuropean Society of Endocrinology (ESE) guidelines provide goals for hypoparathyroidism management but do not define characteristics of chronic hypoparathyroidism that is not adequately controlled. Three European country-specific Delphi panels were conducted to gain consensus on these characteristics.MethodsDelphi panels...
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Unexpected pressure swings in a positive airway pressure device: an unknown cause for bad CPAP tolerance?: Efficient continuous positive airway pressure (CPAP) treatment requires the pressure to be as constant as possible during the respiratory cycle [1]. Significant differences in pressure stability of devices have been described previously [2]. These reported pressure changes occur during inspiration, causing a drop in the CPAP pressure [2, 3]. Technical improvements have since been implemented...
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Characteristics and Severity of Agitation Associated With Use of Sedatives and Restraints in the Emergency Department: Agitated patients frequently present to emergency departments, but limited evidence exists regarding clinical decisions to use chemical sedatives and physical restraints.
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Interfacial Characterization of Dentin Conditioned with Chitosan Hydroxyapatite Precursor Nanocomplexes Using Time-of-flight Secondary Ion Mass Spectrometry: The purpose of this study was to evaluate the effect of chitosan-hydroxyapatite precursor (C-HA) nanocomplex conditioning on the chemical modifications at the tricalcium silicate sealer-dentin interface using time-of-flight secondary ion mass spectrometry.
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Prospective intra/inter-observer evaluation of pre-brachytherapy cervical cancer tumor width measured in TRUS and MR imaging: Ultrasound (US) imaging has been proved as an excellent diagnostic tool in gynecology and, due to its wide availability and limited cost, is under intense investigation as base for dose adaptation in cervical ...
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Different vascular healing process between bioabsorbable polymer-coated everolimus-eluting stents versus bioresorbable vascular scaffolds via optical coherence tomography and coronary angioscopy (the ENHANCE study: ENdothelial Healing Assessment with Novel Coronary tEchnology): AbstractRecent clinical trials have raised concerns about the safety and efficacy of ABSORB™ bioresorbable vascular scaffolds (BVS). The difference in the vascular healing process between SYNERGY™ bioabsorbable polymer-coated...
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Thiopurines with low-dose allopurinol (ThiLDA)—a prospective clinical one-way crossover trial: AbstractPurposeMany patients with Crohn's disease (CD) and ulcerative colitis (UC) who have a high 6-methylmercaptopurine/6-thioguanine (6-MMP/6-TGN) ratio receive allopurinol 100 mg in addition to thiopurines to optimize metabolite concentrations. However, some patients do not tolerate allopurinol at this dosage.The aim of this study was to determine the intra-patient effect of reducing the allopurinol...
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The "Dermal Cage"- Inferiorly Based Dermal Flap Technique for Breast Reconstruction after Mastectomy: "Direct to implant", "one stage" or "immediate" breast reconstruction procedures have became extremely popular in last decade. The additional task of covering the lower pole of the prosthetic implant for stability can be achieved by one of two principle methods. One is the use of ADM (acellular dermal matrix) or alternatively by the use of autologous dermis (inferiorly based dermal flap). In 2013...
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An Assessment of Histological Margins and Recurrence of Completely excised Cutaneous SCC: There is a paucity of data relating histological margins of cutaneous squamous cell carcinoma (cSCC) and local recurrence. Retrospective data was collected for 721 patients with cSCC treated at Queen Victoria Hospital, UK and followed up for five years. The local recurrence rate was 6.1%, the mean time to recurrence was 12.61 months and 93% of recurrences occurred within two years. 66% of recurrences had a deep...
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Computerized programs for cancer survivors with cognitive problems: a systematic review: AbstractPurposeThis study aimed to review and identify characteristics and lessons learned from studies on computerized cognitive interventions for cancer survivors (CSs) with cognitive dysfunction, exploring the content and results of interventions.MethodsStudies were collected from the CINAHL, Web of Science, PubMed, and PsycINFO databases.ResultsSeven articles that met the inclusion criteria were included....
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Ectopic Thyroid Gland Tissue in the Liver:
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A case of amyloid light-chain amyloidosis presenting with submucosal hematoma and bleeding in the upper gastrointestinal tract:
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An Updated Review on Ablative Treatment of Pancreatic Cystic Lesions: Pancreatic cysts are common and often incidentally detected on abdominal imaging. Their prevalence in asymptomatic individuals depends on the screening modality used. The incidence of these lesions increases with age and may be detected in nearly half of elderly patients undergoing high-resolution MRI.Some, but not all, pancreas cysts have malignant potential. The overall risk is small but induces significant anxiety for the patient....
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High-grade small-bowel obstruction caused by a migrated lumen-apposing metal stent:
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You forgot a staple! A septal defect in the ileal pouch-anal anastomosis:
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Reducing Asthma Attacks in Children using Exhaled Nitric Oxide as a biomarker to inform treatment strategy: a randomised trial (RAACENO): Childhood asthma is a common condition. Currently there is no validated objective test which can be used to guide asthma treatment in children. This study tests the hypothesis that the addition of fractional e...
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Pregnancy and childbirth after an iliac crest free flap: We report two successful pregnancies and vaginal deliveries by patients who had previously had deep circumflex iliac artery free flaps that had been harvested for reconstruction in the head and neck.
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Exploring the relation between patients' resilience and quality of life after treatment for cancer of the head and neck: Resilience, which is a measure of a patient's ability to recover from a traumatic event, varies among the general population, and previous studies have suggested that it has an important influence on a patient's quality of life. We conducted a study of patients treated for cancer of the head and neck to investigate the relation between scores for resilience and quality of life...
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Clinical experience and results with a Rhombic Plate for transoral endoscopically-assisted osteosynthesis of fractures of the condylar neck: The intraoral approach is favoured by many patients and surgeons for the treatment of fractures of the condylar neck, but the limited space offered by this approach can make positioning and fixation of the osteosynthesis plate difficult. A rhombic-shaped plate was designed specifically for use with the intraoral approach, and introduced into our clinical practice...
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The stair step genioplasty: a modification of the oblique sagittal sliding genioplasty: The genioplasty has been a versatile procedure in the repertoire of a maxillofacial surgeon ever since it was conceptualised by Trauner and Obwegeser in 1957.1 In most situations, a chin procedure improves the overall aesthetic profile and renders a better definition to the jaw line, which explains the evolution of various modifications. We introduce a modification to the existing oblique sagittal sliding genioplasty2...
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Comparison of the piezoelectric cutter with a conventional cutting technique in orthognathic surgery
Comparison of the piezoelectric cutter with a conventional cutting technique in orthognathic surgery: The use of a piezoelectric cutter has been reported to improve outcomes in orthognathic surgery, particularly with regards to neurosensory disturbance of the inferior alveolar nerve. The aims of this retrospective longitudinal cohort study were to compare outcomes regarding neurosensory disturbance, and operating time. During two 15-month periods a single surgeon treated 24 consecutive patients with...
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Congenital syngnathia: review of clinical profile and proposal of a new classification-based management protocol: Syngnathia is a rare congenital anomaly that presents as fusion of the jaws. The aims of this study were to review the clinical profile of reported cases of syngnathia available in the literature with a view to suggesting a classification that may simplify the understanding of syngnathia and to propose an appropriate management protocol. A PubMed database search of articles published...
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Magnetic diatomite for pesticide removal from aqueous solution via hydrophobic interactions: AbstractPesticides are highly hazardous chemicals for the environment and human health and their use in agriculture is constantly increasing. Although 1,1,1-trichloro-2,2-bis(4-chlorophenyl) ethane 4,4′-DDT was banned at developed countries, it is still one of the most dangerous of chemical due to accumulation in the environment. It is known that the toxicity of DDT affects some enzyme systems biochemically....
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FDG PET/TC vs. NaF PET/TC en policondritis recidivante: Publication date: Available online 5 October 2019Source: Revista Española de Medicina Nuclear e Imagen MolecularAuthor(s): Y. Liu, Y. Xia, Y. Chen, L. CaiFigures (3)
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Sucrose isomers as alternative sweeteners: properties, production, and applications: AbstractIn the daily diet, sweeteners play an indispensable role. Among them, sucrose, a widely occurring disaccharide in nature, is a commonly used sweetener. However, the intake of sucrose can cause a rapid increase in blood glucose, which leads to a number of health problems. Therefore, there is an urgent need for possible alternatives to sucrose. Currently, four naturally occurring sucrose isomers, trehalulose,...
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The incidence and interpretation of large differences in EIT-based measures for PEEP titration in ARDS patients: AbstractPositive end-expiratory pressure (PEEP) can be titrated by electrical impedance tomography (EIT). The aim of the present study was to examine the performance of different EIT measures during PEEP trials with the aim of identifying "optimum" PEEP and to provide possible interpretations of largely diverging results. After recruitment (maximum plateau pressure 35 cmH2O), decremental...
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Successful Surgical Treatment for Dysphagia Secondary to Descending Necrotizing Mediastinitis.: Related ArticlesSuccessful Surgical Treatment for Dysphagia Secondary to Descending Necrotizing Mediastinitis.Yonago Acta Med. 2019 Sep;62(3):253-257Authors: Fujiwara K, Koyama S, Fukuhara T, Takeuchi HAbstract Descending necrotizing mediastinitis (DNM) is a life-threatening disease with a high fatality rate that occurs as a complication of deep neck abscess. DNM complicated by severe dysphagia...
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IJMS, Vol. 20, Pages 4939: The Effect of Polyphenols on Hypercholesterolemia through Inhibiting the Transport and Expression of Niemann–Pick C1-Like 1: IJMS, Vol. 20, Pages 4939: The Effect of Polyphenols on Hypercholesterolemia through Inhibiting the Transport and Expression of Niemann–Pick C1-Like 1International Journal of Molecular Sciences doi: 10.3390/ijms20194939Authors: Shoko Kobayashi The Niemann–Pick C1-like 1 (NPC1L1) protein is a cholesterol transporter that is expressed in the small...
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Leitliniengerechte Narbentherapie mit Silikongel: Insbesondere bei tieferen Hautläsionen durch Unfälle, Operationswunden oder Verbrennungen bleiben sichtbare Narben zurück. Auffällig sind dabei hypertrophe Narben und Keloide. Zu deren Prävention und Behandlung können topische Narbentherapeutika eingesetzt werden. Neben den Narbentopika auf Silikonbasis haben sich seit langer Zeit auch Präparate mit Zwiebelextrakt bewährt. Wie sieht nun die Therapie unter Berücksichtigung der deutschen und der internationalen...
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Regenerative Zellen in der ästhetischen und rekonstruktiven Medizin: Regenerative Zellen werden zur Gewebekonstruktion und -regeneration genutzt. Dabei hat sich Fettgewebe als Quelle aufgrund guter Verfügbarkeit und leichter Gewinnung in der kosmetischen und plastischen Chirurgie durchgesetzt. Jedoch gibt es bei der Aufbereitung des zu transplantierenden Zellgemischs einiges zu beachten.
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Elektrochemotherapie steigert Bleomycinwirkung: Die intraläsionale Behandlung ungualer Warzen mit Bleomycin in Verbindung mit Elektroporation erbrachte in einer brasilianischen Studie eine signifikant höhere Heilungsrate als die Bleomycintherapie allein.
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Lichturtikaria nach Schweregrad effizient behandeln: Eine auf die Schwere der Erkrankung abgestimmte Therapie erzielt bei der Lichturtikaria gute Erfolge, wie eine neue israelische Studie zeigt. Bei refraktärer Krankheit kann die Behandlung um Omalizumab erweitert werden.
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Skalpell und Laser langfristig besser als Schaum: Für die invasive Therapie von Varizen stehen verschiedene Verfahren zur Auswahl — mit unterschiedlich guten Langzeitergebnissen. Einer randomisierten Vergleichsstudie zufolge ist die Schaumsklerosierung nur zweite Wahl.
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Lidocain und Prilocain lindern Schmerzen: Bei Patienten, die sich einer ablativen fraktionierten CO2-Lasertherapie unterziehen, treten insbesondere in den 60 Minuten nach der Behandlung Hitzeempfindungen und Brennen auf. Abhilfe schaffen könnte ein topisches Anästhetikum mit Lidocain und Prilocain mithilfe der Nanotechnologie.
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Die atopische Dermatitis als Vorbote: ZusammenfassungDie atopische Dermatitis gehört zu den häufigsten chronisch-entzündlichen Hauterkrankungen. Sie steht im Verdacht, andere Erkrankungen zu begünstigen — darunter kardiovaskuläre Ereignisse, chronisch-entzündliche Darmerkrankungen oder Infektionskrankheiten. Ein Zusammenhang ist aber nicht in allen Fällen eindeutig belegt.
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Management of Difficult Tracheal Intubation: A Closed Claims Analysis.: Related ArticlesManagement of Difficult Tracheal Intubation: A Closed Claims Analysis.Anesthesiology. 2019 Oct;131(4):818-829Authors: Joffe AM, Aziz MF, Posner KL, Duggan LV, Mincer SL, Domino KBAbstract WHAT WE ALREADY KNOW ABOUT THIS TOPIC: Difficult or failed intubation is a major contributor to morbidity for patients and liability for anesthesiologists.Updated difficult airway management guidelines and incorporation...
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Transvaginal excision of rectal stromal tumors: case reports and a literature review: AbstractBackgroundGastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. Rectal locations are very rare, and minimally invasive surgery is a good choice for the treatment of rectal GISTs.Case presentationTwo women each had a mass located on the lower vaginal-rectal space as determined by transvaginal ultrasound (TV-US), pelvis MR imaging, and colonoscopy. The...
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A Near Infrared Fluorescent pH Sensing Film for Wound Milieu pH Monitoring: AbstractStudies have shown that wound pH is a potentially influential factor in the healing process. Due to the flaws of traditional pH measurement approaches, wound pH measurement has not become part of current standard of care. A near‐infrared pH sensitive ratiometric film was created and characterized for measuring wound pH. This film was fabricated by physically absorbing poly (N‐isopropyl Acrylamide) nanoparticles conjugated...
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European Journal of Surgical Oncology (EJSO)Younger Women: Do They Present With More Advanced And Higher Grade Breast Cancers?Publication date: November 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 11Author(s): Yvette Jaffe, Juan McDonnell, Fawzia Imtiaz-Crosbie, Victor JaffeEuropean Journal of Surgical Oncology (EJSO)Sat Oct 05, 2019 06:10Improvement in the Quality Of Lymph Node Harvests Using Extra-Levator Abdominoperineal Excisions Compared With Conventional TechniquesPublication...
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Pediatric OtorhinolaryngologyQuality of life of children with hearing loss in special and mainstream education: a longitudinal studyPublication date: Available online 5 October 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Tirza F.K. van der Straaten, Carolien Rieffe, Wim Soede, Anouk P. Netten, Evelien Dirks, Anne Marie Oudesluys-Murphy, Friedo W. Dekker, Stefan Böhringer, Johan H.M. Frijns, DECIBEL Collaborative study groupAbstractObjectivesTo compare the quality...
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JoVE: Journal of Visualized ExperimentsDeveloping Photosensitizer-Cobaloxime Hybrids for Solar-Driven H2 Production in Aqueous Aerobic ConditionsWe have directly incorporated a stilbene-based organic dye into a cobaloxime core to generate a photosensitizer-catalyst dyad for photocatalytic H2 production. We have also developed a simple experimental setup for evaluating the light-driven H2 production by photocatalytic assemblies.JoVE: Journal of Visualized ExperimentsSat Oct 05, 2019 12:17Using Flexible...
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JoVE: Journal of Visualized ExperimentsDeveloping Photosensitizer-Cobaloxime Hybrids for Solar-Driven H2 Production in Aqueous Aerobic ConditionsWe have directly incorporated a stilbene-based organic dye into a cobaloxime core to generate a photosensitizer-catalyst dyad for photocatalytic H2 production. We have also developed a simple experimental setup for evaluating the light-driven H2 production by photocatalytic assemblies.JoVE: Journal of Visualized ExperimentsSat Oct 05, 2019 12:17Using Flexible...
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Nutrients, Vol. 11, Pages 2383: The Impact of Time of Day on Energy Expenditure: Implications for Long-Term Energy BalanceNutrients, Vol. 11, Pages 2383: The Impact of Time of Day on Energy Expenditure: Implications for Long-Term Energy Balance Nutrients doi: 10.3390/nu11102383 Authors: Shaw Leung Jong Coates Davis Blair Huggins Dorrian Banks Kellow Bonham There is evidence to indicate that the central biological clock (i.e., our endogenous circadian system) plays a role in physiological processes...
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