Related ArticlesPEGylated gold nanorods are not cytotoxic to human endothelial cells but affect kruppel-like factor signaling pathway. Toxicol Appl Pharmacol. 2019 11 01;382:114758 Authors: Li X, Tang Y, Chen C, Qiu D, Cao Y Abstract Gold (Au) nanomaterials (NMs), particularly those with PEG surface functionalization, are generally considered to be biocompatible for biomedical applications due to relatively low cytotoxicity. Herein, we investigated...
Thu May 21, 2020 15:23
Evaluating the real-world implementation of the Family Nurse Partnership in England: protocol for a data linkage study. BMJ Open. 2020 May 18;10(5):e038530 Authors: Cavallaro FL, Gilbert R, Wijlaars L, Kennedy E, Swarbrick A, van der Meulen J, Harron K Abstract INTRODUCTION: Almost 20 000 babies are born to teenage mothers each year in England, with poorer outcomes for mothers and babies than among older mothers. A nurse home visitation programme in...
Thu May 21, 2020 15:19
Effect of an editorial intervention to improve the completeness of reporting of randomised trials: a randomised controlled trial. BMJ Open. 2020 May 18;10(5):e036799 Authors: Blanco D, Schroter S, Aldcroft A, Moher D, Boutron I, Kirkham JJ, Cobo E Abstract OBJECTIVE: To evaluate the impact of an editorial intervention to improve completeness of reporting of reports of randomised trials. DESIGN: Randomised controlled trial (RCT). SETTING:...
Thu May 21, 2020 15:19
Association between obesity-related anthropometric indices and multimorbidity among older adults in Shandong, China: a cross-sectional study. BMJ Open. 2020 May 18;10(5):e036664 Authors: Zhang J, Xu L, Li J, Sun L, Qin W Abstract OBJECTIVES: Whether the association between obesity-related anthropometric indices and multimorbidity differs by age among Chinese older adults (aged 65+) is unclear. We aimed to investigate the association between body mass...
Thu May 21, 2020 15:19
Protocol of a randomised controlled trial assessing the impact of physical activity on bone health in children with inflammatory bowel disease. BMJ Open. 2020 May 18;10(5):e036400 Authors: Vanhelst J, Coopman S, Labreuche J, Dupont C, Bertrand V, Djeddi D, Turck D, Ley D Abstract INTRODUCTION: Low bone mineral density (BMD) is a frequent issue in children and adolescents with inflammatory bowel disease (IBD). Several studies in healthy populations have...
Thu May 21, 2020 15:19
Patients' views on involving general practice in bowel cancer screening: a South Australian focus group study. BMJ Open. 2020 May 18;10(5):e035244 Authors: Brown L, Moretti C, Roeger L, Reed R Abstract OBJECTIVES: To explore patients' experiences of bowel cancer screening and its promotion, and perspectives on possible input from general practice for improving screening rates. DESIGN: Qualitative focus group study underpinned by a phenomenological...
Thu May 21, 2020 15:19
Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) for chronic insomnia disorder ('CANSLEEP' trial): protocol for a randomised, placebo-controlled, double-blinded, proof-of-concept trial. BMJ Open. 2020 May 18;10(5):e034421 Authors: Suraev A, Grunstein RR, Marshall NS, D'Rozario AL, Gordon CJ, Bartlett DJ, Wong K, Yee BJ, Vandrey R, Irwin C, Arnold JC, McGregor IS, Hoyos CM Abstract INTRODUCTION: Insomnia is a highly prevalent and costly condition that...
Thu May 21, 2020 15:19
Qualitative accounts from Syrian mental health professionals: shared realities in the context of conflict and forced displacement. BMJ Open. 2020 May 18;10(5):e034291 Authors: Hamid A, Scior K, Williams ACC Abstract OBJECTIVES: To explore the impact of the provision of care of forcibly displaced Syrian mental health professionals (MHPs) to Syrian clients in the community given shared experiences and backgrounds with clients. DESIGN: A qualitative...
Thu May 21, 2020 15:19
Developing a typology of the roles public contributors undertake to establish legitimacy: a longitudinal case study of patient and public involvement in a health network. BMJ Open. 2020 May 18;10(5):e033370 Authors: Barker J, Moule P, Evans D, Phillips W, Leggett N Abstract OBJECTIVE: To identify how public contributors established their legitimacy in the functioning of a patient and public involvement programme at a health network. DESIGN:...
Thu May 21, 2020 15:19
Maximising comfort: how do patients describe the care that matters? A two-stage qualitative descriptive study to develop a quality improvement framework for comfort-related care in inpatient settings. BMJ Open. 2020 May 18;10(5):e033336 Authors: Wensley C, Botti M, McKillop A, Merry AF Abstract OBJECTIVE: To develop a multidimensional framework representing patients' perspectives on comfort to guide practice and quality initiatives aimed at improving...
Thu May 21, 2020 15:19
Magnitude, characteristics and consequences of topical steroid misuse in rural North India: an observational study among dermatology outpatients. BMJ Open. 2020 May 18;10(5):e032829 Authors: Thomas M, Wong CC, Anderson P, Grills N Abstract INTRODUCTION: Current evidence indicates an alarming increase in topical steroid (TS) misuse in India. Data regarding the magnitude and characteristics of this problem in rural India, where 68% of the population resides,...
Thu May 21, 2020 15:19
Patient-centred and economic effectiveness of a decision aid for patients with age-related cataract in China: study protocol of a randomised controlled trial. BMJ Open. 2020 May 18;10(5):e032242 Authors: Zheng Y, Qu B, Jin L, Wang C, Zhong Y, He M, Liu Y Abstract INTRODUCTION: The need for cataract surgery is on the rise due to our ageing population and high demands for greater visual functioning. Although the majority of patients want to participate...
Thu May 21, 2020 15:19
Publication date: June 2020Source: American Journal of Infection Control, Volume 48, Issue 6Author(s):
Thu May 21, 2020 15:17
Publication date: June 2020Source: American Journal of Infection Control, Volume 48, Issue 6Author(s):
Thu May 21, 2020 15:17
Publication date: June 2020Source: American Journal of Infection Control, Volume 48, Issue 6Author(s):
Thu May 21, 2020 15:17
Publication date: June 2020Source: American Journal of Infection Control, Volume 48, Issue 6Author(s):
Thu May 21, 2020 15:17
Publication date: June 2020Source: American Journal of Infection Control, Volume 48, Issue 6Author(s):
Thu May 21, 2020 15:17
Temporary Migration for Training: A Special Case: Erratum. Ann Plast Surg. 2020 Jun;84(6):732 Authors: PMID: 32433334 [PubMed - as supplied by publisher]
Thu May 21, 2020 15:03
Response to: "Clinical Application of Precise Composite Breast Augmentation". Ann Plast Surg. 2020 Jun;84(6):731-732 Authors: Vinci V, Maione L, Lozito A, Viti A, Klinger M PMID: 32433333 [PubMed - as supplied by publisher]
Thu May 21, 2020 15:03
Reconstruction of Complex Abdominal Wall Defect With Autogenous Pedicled Demucosalized Seromuscular Flap. Ann Plast Surg. 2020 Jun;84(6):697-699 Authors: Asaad M, Vyas KS, Tran NV Abstract Abdominal wall reconstruction is indicated when 1 or more of the abdominal wall components (skin, fascia, or muscle) are either injured or absent. When faced with defects requiring flap reconstruction, the decision regarding flap choice should take into consideration...
Thu May 21, 2020 15:03
Alternative Perforator Options for Insufficient Profunda Artery Perforators: A Case and Anatomical Study. Ann Plast Surg. 2020 Jun;84(6):679-683 Authors: Winters H, Tielemans HJP, van Wegen M, Hupkens P, Slater NJ, Ulrich DJO Abstract INTRODUCTION: The profunda artery perforator (PAP) flap can be an alternative to the deep inferior epigastric artery flap. However, in some cases, the PAP may not be adequate to perfuse the whole flap. In this study, we...
Thu May 21, 2020 15:03
Three-Dimensional Visualization for Extended Deep Inferior Epigastric Perforator Flaps. Ann Plast Surg. 2020 May 12;: Authors: Cui H, Ding M, Mao Y, Zhou P, Sun C, Tang M, Xu D Abstract PURPOSE: The aim of the study was to provide an applied and digital anatomical basis of acquiring extended deep inferior epigastric perforator (DIEP) flaps for clinical use. METHODS: Five formalin-soaked specimens were received red latex injection and dissected...
Thu May 21, 2020 15:03
Impact of delayed neoadjuvant systemic chemotherapy on overall survival among breast cancer patients. Oncologist. 2020 May 20;: Authors: Gagliato DM, Lei X, Giordano SH, Valero V, Barcenas CH, Hortobagyi GN, Chavez-MacGregor M Abstract BACKGROUND: Delays in the initiation of therapy among patients with early stage breast cancer (BC), can negatively impact outcomes. Patients treated with neoadjuvant systemic chemotherapy (NSC) usually display tumors with...
Thu May 21, 2020 15:02
Breast-conserving surgery without axillary lymph node surgery or radiotherapy is safe for HER2-positive and triple negative breast cancer patients over 70 years of age. Breast Cancer Res Treat. 2020 May 19;: Authors: Zhong Y, Xu Y, Zhou Y, Mao F, Lin Y, Guan J, Shen S, Pan B, Wang C, Peng L, Huang X, Li Y, Wang X, Sun Q Abstract PURPOSE: The prognosis of elderly patients with hormone receptor-positive breast cancer is very good, and their survival is...
Thu May 21, 2020 15:02
Neoadjuvant Endocrine Therapy in Breast Cancer: Current Knowledge and Future Perspectives. Int J Mol Sci. 2020 May 16;21(10): Authors: Barchiesi G, Mazzotta M, Krasniqi E, Pizzuti L, Marinelli D, Capomolla E, Sergi D, Amodio A, Natoli C, Gamucci T, Vizza E, Marchetti P, Botti C, Sanguineti G, Ciliberto G, Barba M, Vici P Abstract In locally advanced (LA) breast cancer (BC), neoadjuvant treatments have led to major achievements, which hold particular...
Thu May 21, 2020 15:02
Publication date: Available online 21 May 2020Source: Gait & PostureAuthor(s): Stephanie Voss, Jessica Joyce, Alexandras Biskis, Medha Parulekar, Nicholas Armijo, Cris Zampieri, Rachel Tracy, Sasha Palmer, Marie Fefferman, Bichun Ouyang, Yuanqing Liu, Elizabeth Berry-Kravis, Joan A. O’Keefe
Thu May 21, 2020 15:00
Publication date: Available online 20 May 2020Source: Gait & PostureAuthor(s): T. Rantalainen, W.P. Teo, N.D. Ridgers, N.D. Nuzum, L. Valente, H. Macpherson
Thu May 21, 2020 15:00
Publication date: Available online 20 May 2020Source: Gait & PostureAuthor(s): Yasir S. Alshehri, Wen Liu, Scott Mullen, Milind Phadnis, Neena K. Sharma, Marcio dos Santos
Thu May 21, 2020 15:00
Publication date: Available online 20 May 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): R. Xu, N. Ye, S. Zhu, B. Shi, J. Li, W. Lai
Thu May 21, 2020 14:58
Publication date: Available online 20 May 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): J.-p. Ding, B. Chen, W.-j. Qian, S.-w. Bao, H.-y. Zhao
Thu May 21, 2020 14:58
Idiopathic Subglottic Tracheal Stenosis Misdiagnosed As Vocal Cord Dysfunction and Successfully Treated with Laser and Controlled Radial Expansion Balloon Dilation. Cureus. 2020 Apr 16;12(4):e7702 Authors: Karakattu SM, Vijayan K, Haddad I, El Abbassi A Abstract Idiopathic tracheal stenosis (ITS) is a rare condition, and diagnosis of exclusion should be suspected in patients with exercise intolerance, wheezing, and dyspnea on exertion with a flow-volume...
Thu May 21, 2020 14:57
Association of Snoring with Prediabetes and Type 2 Diabetes Mellitus: The Cardiovascular and Metabolic Diseases Etiology Research Center Cohort. Diabetes Metab J. 2020 Apr 16;: Authors: Cho SMJ, Lee H, Shim JS, Kim HC Abstract BACKGROUND: Evidence suggests that habitual snoring is an independent risk factor for poor glycemic health. We examined the associations between snoring with prediabetes and diabetes in Korean population. METHODS: Self-reported...
Thu May 21, 2020 14:57
The Impact of Nasal Obstruction and Functional Septorhinoplasty on Sleep Quality. Facial Plast Surg Aesthet Med. 2020 May 19;: Authors: Hismi A, Yu P, Locascio J, Levesque PA, Lindsay RW Abstract Importance: Functional septorhinoplasty (FSRP) has been shown to improve both global and disease-specific quality of life (QOL). However, the mechanism by which FSRP improves QOL has not been fully defined. We reasoned that NAO may impact sleep quality and,...
Thu May 21, 2020 14:57
Drp1-dependent remodeling of mitochondrial morphology triggered by EBV-LMP1 increases cisplatin resistance. Signal Transduct Target Ther. 2020 May 20;5(1):56 Authors: Xie L, Shi F, Li Y, Li W, Yu X, Zhao L, Zhou M, Hu J, Luo X, Tang M, Fan J, Zhou J, Gao Q, Wu W, Zhang X, Liao W, Bode AM, Cao Y Abstract Latent membrane protein 1 (LMP1) is a major Epstein-Barr virus (EBV)-encoded oncoprotein involved in latency infection that regulates mitochondrial functions...
Thu May 21, 2020 14:57
Treatment of displaced radial neck fractures under ultrasonographic guidance in children. Int Orthop. 2020 May 20;: Authors: Su Y, Jin C, Duan X, Wang J, Li K Abstract PURPOSE: This study aimed to evaluate the feasibility of reduction under ultrasonographic (US) guidance with Kirschner wires (K-wires) and fixation with elastic stable intramedullary nails (ESINs) in the treatment of radial neck fractures (RNFs). METHODS: This retrospective study...
Thu May 21, 2020 14:57
Publication date: Available online 20 May 2020Source: The Journal of Prosthetic DentistryAuthor(s): LÃvia Fiorin, Izabela C.M. Moris, Adriana C.L. Faria, Ricardo F. Ribeiro, Renata C.S. Rodrigues
Thu May 21, 2020 14:45
Introduction Retinoblastoma (RB) is one common pediatric malignant tumor with dismal outcomes. Heterogeneity of RB and subtypes of RB were identified but the association between the subtypes of RB and RB progression have not been fully investigated. Methods Four public datasets were downloaded from Gene expression omnibus and normalization was performed to remove batch effect. Two public datasets were explored to obtain the RB progression gene signatures by differentially expression analysis...
Thu May 21, 2020 03:00
Vitiligo is a chronic asymptomatic disorder affecting melanocytes from the basal layer of the epidermis which leads to a patchy loss of skin color. Even though it is one of the neglected disease conditions, people suffering from vitiligo are more prone to psychological disorders. As of now, various studies have been done in order to project auto-immune implications as the root cause. To understand the complexity of vitiligo, we propose the Vitiligo Information Resource (VIRdb) that integrates both...
Thu May 21, 2020 03:00
Background Red palm weevil Rhynchophorus ferrugineus (Coleoptera: Curculionidae) is one of the most destructive insects for palm trees in the world. However, its genome resources are still in the blank stage, which limits the study of molecular and growth development analysis. Methods In this study, we used PacBio Iso-Seq and Illumina RNA-seq to first generate transcriptome from three developmental stages of R. ferrugineus...
Thu May 21, 2020 03:00
Enterococcus is a genus of Gram-positive bacteria that are commensal to the gastrointestinal tracts of humans but some species have been increasingly implicated as agents of nosocomial infections. The increase in infections and the spread of antibiotic-resistant strains have contributed to renewed interest in the discovery of Enterococcus phages. The aims of this study were (1) the isolation, characterization, and genome sequencing of a phage capable of infecting an antibiotic-resistant E. faecalis...
Thu May 21, 2020 03:00
Background Avian pathogenic Escherichia coli (APEC), an important extraintestinal pathogenic E. coli, causes colibacillosis, an acute and mostly systemic disease involving multiple organ lesions such as meningitis. Meningitis-causing APEC can invade the host central nervous system by crossing the blood–brain barrier (BBB), which is a critical step in the development of meningitis. However, the bacteria-host interaction mechanism in this process remains unclear. Methods In this study,...
Thu May 21, 2020 03:00
Background Bisphosphonate therapy has become a popular treatment for osteoporosis, Paget’s disease, multiple myeloma, osteogenesis imperfecta, myocardial infarction, and cancer despite its serious side effects. Bisphosphonate-induced molecular signaling changes in cells are still not clearly elucidated. Methods As bisphosphonates are primarily engulfed by macrophages, we treated RAW 264.7 cells (a murine macrophage cell line) with pamidronate and investigated global protein expressional...
Thu May 21, 2020 03:00
Background Anaplastic thyroid carcinoma (ATC) is a rare malignant tumor with a poor prognosis. However, there is no useful clinical prognostic predictive tool for ATC so far. Our study identified risk factors for survival of ATC and created a reliable nomogram to predict overall survival (OS) and cancer-specific survival (CSS) of patients with ATC. Methods A total of 1,404 cases of ATC diagnosed between 1983 and 2013 were extracted from on the Surveillance, Epidemiology and End Results...
Thu May 21, 2020 03:00
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