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Tuesday, April 10, 2018

Genes, Vol. 9, Pages 204: Wnt Signaling in Thyroid Homeostasis and Carcinogenesis

Genes, Vol. 9, Pages 204: Wnt Signaling in Thyroid Homeostasis and Carcinogenesis

Genes doi: 10.3390/genes9040204

Authors: Kim Ely Lindsay Bischoff Vivian Weiss

The Wnt pathway is essential for stem cell maintenance, but little is known about its role in thyroid hormone signaling and thyroid stem cell survival and maintenance. In addition, the role of Wnt signaling in thyroid cancer progenitor cells is also unclear. Here, we present emerging evidence for the role of Wnt signaling in somatic thyroid stem cell and thyroid cancer stem cell function. An improved understanding of the role of Wnt signaling in thyroid physiology and carcinogenesis is essential for improving both thyroid disease diagnostics and therapeutics.



from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader https://ift.tt/2Jvfo3v

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