The gut microbiota influences anticancer immunosurveillance and general health

The gut microbiota influences anticancer immunosurveillance and general health

The gut microbiota influences anticancer immunosurveillance and general health, Published online: 10 April 2018; doi:10.1038/s41571-018-0006-2

Emerging evidence indicates that the composition of the intestinal microbiota influences anticancer immunosurveillance and therefore the effectiveness of anticancer therapies, especially immune-checkpoint inhibitors. Herein, key contributors to this field of research discuss these connections between gut bacteria, anticancer immunity, and general health, with a focus on specific bacterial species consistently associated with favourable clinical outcomes of anticancer immunotherapy, and explore the potential mechanisms.

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