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Tuesday, November 6, 2018

Histological and inflammatory analysis to diagnostic method of proximal gingivitis by flossing

Abstract

Objectives

The aim of this study was to assess with histological and inflammatory analysis the use of flossing as a diagnostic method for detecting proximal gingivitis.

Material and methods

This is a diagnostic accuracy paper composed of two different studies. In the first study, three groups were identified based on papilla status: bleeding (+) with both methods (N = 26); bleeding (+) with dental floss, but no bleeding (−) with probing (N = 26); and no bleeding (−) with either method (N = 26). One papilla from all 78 participants was biopsied and analyzed for the determination of inflammatory infiltrate and percentage of collagen fibers. Sensibility, specificity, positive and negative predictive, and accuracy values were analyzed. In the second study, the volume of gingival crevicular fluid (GCF) was analyzed in 49 participants with flossing+/probing− and flossing−/probing− at contralateral proximal sites. The GCF volume was compared between these sites (n = 172).

Results

Significantly greater frequencies of moderate/intense inflammation were found in the flossing+/probing+ (100%) and flossing+/probing− (92.3%) groups compared to those in the flossing−/probing− (0%) group. Significantly different percentages of collagen fibers were found among the three groups (flossing+/probing+ (40.90 ± 3.68); flossing+/probing− (45.78 ± 4.55); flossing−/probing− (60.01 ± 36.66)) (P < 0.001). Dental floss increased the balance between sensitivity and specificity values and showed highest positive predictive (100%) and accuracy (97%) values. Among the 172 sites evaluated, positive bleeding sites had a significantly greater volume of GCF (38 (27–68)) than negative sites (25 (16–51)) (P < 0.001).

Conclusions

The findings suggest that flossing can be used as a diagnostic method for proximal gingivitis in subjects with no history of periodontitis.

Clinical relevance

Dental floss can be used as a complementary diagnostic method for proximal gingivitis in adults without clinical attachment loss in clinical practice as well as epidemiology studies.



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