Vaccine delivery by precipitation (VDBP) induces tolerance to poison ivy.

Previous poison ivy vaccines, comprising urushiol in sterile vegetable oils injected SQ, were withdrawn in 1994 for failure to demonstrate statistical efficacy (personal communication J.Slater). We'd found them anecdotally safe and effective in some patients. For highly allergic patients for whom avoidance was not practical we offered immunotherapy with home-made vaccines in accordance with Declaration of Helsinki guidelines for ethical use of "unproven interventions"1. Informed consent was obtained from all patients.

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