GR Extinguishes Inflamed Chromatin, and NF-κB Evacuates

Publication date: 15 August 2017
Source:Immunity, Volume 47, Issue 2
Author(s): Maria Fasolino, Golnaz Vahedi
In this issue of Immunity,Oh et al. (2017) provide insight into the molecular effects of glucocorticoid receptor (GR) activation at a clinically relevant time point, after an inflammatory stimulus. They report that GR activation causes a global reduction in NF-κB binding, as well as time-dependent transcriptional effects.

Teaser

In this issue of Immunity, Oh et al. (2017) provide insight into the molecular effects of glucocorticoid receptor (GR) activation at a clinically relevant time point, after an inflammatory stimulus. They report that GR activation causes a global reduction in NF-κB binding, as well as time-dependent transcriptional effects.


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