Radiological abnormalities following bronchial thermoplasty: is the pathophysiology understood?

We read with great interest the paper by Debrayet al. [1] reporting on early radiological lung abnormalities on computed tomography (CT) of the chest after bronchial thermoplasty (BT). The described findings in 13 patients are in line with our observations in 12 patients with severe asthma treated with BT in the TASMA trial (http://ift.tt/PmpYKN identifier number NCT02225392). Transient radiological abnormalities were seen after all 36 BT procedures, predominantly consisting of peribronchial consolidations with ground-glass opacities (figure 1a and c), partial occlusions/filling of bronchial lumen and atelectasis. Furthermore, we also observed a residual bronchial dilatation in a single case [2].

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