Third-hand smoke exposure and resultsEmine ArguderEurasian Journal of Pulmonology 2019 21(2):81-86Diseases and deaths due to smoking are still a major public health problem, which is still the leading cause of death in the world. Today, the harmful effects of active smoking and second hand cigarette smoke on health are clearly known. However, the concept of third-hand smoke (THS) exposure, a new concept, is a relatively new definition in the area of environmental and public health. The third-hand...
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Cardiac cachexia: the mandate to increase clinician awarenessPurpose of review Heart failure is a frequent problem in an ageing population, associated with high rates of morbidity and mortality. Today, it is important to not only treat heart failure itself but also the related comorbidities. Among them, cardiac cachexia is one of the major challenges. It is a complex multifactorial disease with a negative impact on quality of life and prognosis. Therefore, prevention, early recognition and treatment...
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Harnessing the potential of digital health in the WHO South-East Asia Region: sustaining what works, accelerating scale-up and innovating frontier technologiesPoonam Khetrapal Singh, Mark LandryWHO South-East Asia Journal of Public Health 2019 8(2):67-70Bangladesh's digital health journey: reflections on a decade of quiet revolutionMuhammad Abdul Hannan Khan, Valeria de Oliveira Cruz, Abul Kalam AzadWHO South-East Asia Journal of Public Health 2019 8(2):71-76Bangladesh has made remarkable progress...
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Complications Associated With Electromyography: A Systematic ReviewObjective To systematically review the available literature concerning complications due to electromyography (EMG) as well as review those associated with nerve conduction studies (NCS). Design A systematic review was undertaken of Medline and Cochrane Central Register of Controlled Trials. Any complication related to clinical EMG written in English were included, and all bibliographies were scanned for missed articles. Results A...
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Lipid changes due to tenofovir alafenamide are reversible by switching back to tenofovir disoproxil fumarateObjective: The aim of the present study is to assess the effect of tenofovir alafenamide (TAF) and tenofovir disoproxil fumarate (TDF) on lipids in patients switching from TDF to TAF and back. Methods: Retrospective data collection on patients who were initially switched from TDF to TAF and switched back to TDF after generics of TDF became available. Results: In total 385 patients were included....
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Snowstorm appearance of synovial fluid on musculoskeletal ultrasoundCheng-Hsun Lu, Ko-Jen LiJournal of Medical Ultrasound 2019 27(3):119-120Thickness of the plantar fascia in asymptomatic subjectsLova Hasina Rajaonarison Ny Ony Narindra, Nicolas Fanantenana Herinirina, Holitiana Rakotonirina, Gabrielle Emmylou Andrianah, Hasina Dina Ranoharison, Rado Randriamboavonjy, Ahmad AhmadJournal of Medical Ultrasound 2019 27(3):121-123Objectives: The objectives of this study are to determine the average and...
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Subclinical Auditory Neural Deficits in Patients With Type 1 Diabetes MellitusObjectives: Diabetes mellitus (DM) is associated with a variety of sensory complications. Very little attention has been given to auditory neuropathic complications in DM. The aim of this study was to determine whether type 1 DM (T1DM) affects neural coding of the rapid temporal fluctuations of sounds, and how any deficits may impact on behavioral performance. Design: Participants were 30 young normal-hearing T1DM patients,...
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Reliability and validity of on-road driving tests in vulnerable adults: a systematic reviewThe on-road driving test is considered a 'gold standard' evaluation; however, its validity and reliability have not been sufficiently reviewed. This systematic review aimed to map out and synthesize literature regarding on-road driving tests using the Consensus-based Standards for the Selection of Health Measurement Instruments checklist. Cochrane Library, PubMed, CINAHL, and Web of Science databases were searched...
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Adult CranioplastyObjectives: After reading this article, the participant should be able to: Understand the etiology of cranial defects. Understand the anatomy of the cranium. Understand the importance of the preoperative workup in the cranial reconstruction decision-making process. Describe the options available for calvarial reconstruction including autologous and alloplastic materials. Describe the basic differences between available alloplastic materials. Understand the intraoperative and postoperative...
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Factors associated with organ donation by trauma patients in Nova ScotiaBackground Trauma patients represent a significant pool of potential organ donors (PODs), and previous research suggests that this population is underutilized for organ donation (OD). Our objective was to assess factors associated with OD in the trauma population. Methods We retrospectively analyzed OD in Nova Scotia over a 7-year period (2009-2016) using data from the Nova Scotia Trauma Registry (NSTR) and Nova Scotia Legacy...
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New models show gut–brain transmission of Parkinson disease pathologyHeather Wood p491 | doi:10.1038/s41582-019-0241-x PDF Predicting progression to AD using a deep-learning model Rebecca Kelsey p492 | doi:10.1038/s41582-019-0236-7 PDF Different clinical profiles in Huntington disease show distinct patterns of brain alterations Rebecca Kelsey p492 | doi:10.1038/s41582-019-0237-6 PDF Antibiotic use might increase risk of ALS Rebecca Kelsey p492 | doi:10.1038/s41582-019-0238-5 PDF Drug reduces excess...
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Psychological working conditions and predictors of occupational stress among nurses, Salaga Government Hospital, Ghana, 2016Basil Benduri Kaburi et al.Stress is the psychological and physiological response to undesirable experiences generally termed as stressors. Though "stress" is more commonly thought of as harmful, responses to stress are a spectrum that stretch from the less discussed "eustress" - where positive responses such as innovation and improved productivity result, to "distress" - which...
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Intraoperative Electrocochleography in Patients With Menière's Disease Undergoing Endolymphatic Sac Decompression and Shunt SurgeryHypothesis: Objective physiologic changes measured using electrocochleography at the round window (ECOGRW) are observable during endolymphatic sac decompression and shunt surgery (ELS). Background: Limited effective treatment options are available to patients with Menière's disease (MD) who have failed conservative management, experience persistent vertigo symptoms, and...
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2019-2020 Flu Season Vaccine Recommendations CDC published the annual MMWR Recommendations & Reports on the use of influenza vaccine for the 2019-20 season. This report updates the 2018–19 recommendations of the Advisory Committee on Immunization Practices (ACIP) regarding the use of seasonal flu vaccines. Routine annual flu vaccination is recommended for all persons aged ≥6 months who do not have contraindications, using a licensed, recommended, and age-appropriate vaccine. Learn MoreSTEM Educational...
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Malaria Cell Atlas Encompasses Transcriptomic Profiles Throughout Parasite's Life Cycle,Published on Aug 22, 2019premiumTranscriptome-Based HPV Assay Shows Correlation With High-Grade CytologyPublished on Aug 30, 2019Sample Normalization with Optimized Nucleic Acid ExtractionDownload this application note to learn about how RNAGEM's excellent yield linearity provides a superior approach to estimating total RNA quantity for sample normalization.Download it from GenomeWeb's White Paper Channel.
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1.Don't stop the champions of research now: a brief history of head and neck pathology developments.Science.gov (United States)Thompson, Lester D R; Lewis, James S; Skálová, Alena; Bishop, Justin A2019-08-23 PubMedDOI: 10.1016/j.humpath.2019.08.017 ISSN: 0046-8177Keywords: Head;Neck;Salivary Gland Neoplasms;Oropharyngeal;Pathology, Surgical;Immunohistochemistry, Paranasal Sinus Neoplasms/Pathology;MolecularThe field of Head and Neck Pathology was just developing 50years ago, but has certainly come...
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A Mental Health Crisis: Real Danger for EMS,Provide your personnel with resources on dealing with stress, understanding PTSD and depression with courses from EMS1 Academy.Download course catalogFEATURED CONTENT5 tips for airway management in the bariatric patientBy Kelly GraysonPre-oxygenate, evaluate for LEMONS and position a patient of any size correctly to help secure an airwayFire chief describes unprecedented preparations for "Storm Area 51" eventBy Janelle FoskettTeams are working on multiple...
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Severe postoperative dysphagia as an early predictor for decreased overall survival in patients with oral cancerPublication date: September 2019Source: Journal of Cranio-Maxillofacial Surgery, Volume 47, Issue 9Author(s): Christoph Klingelhöffer, Annegret Obst, Tobias Ettl, Johannes Meier, Steffen Müller, Torsten Reichert, Gerrit SpanierAbstractObjectivesThe aim of this retrospective study was to analyze the early postoperative swallowing outcome in oral cancer patients considering risk factors and...
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Genes Are Key to Oral Health & Beyond,International study reveals shared genetic links between dental & metabolic diseases.NIDCR • August 23, 2019Addressing Gender Inequality Among Dental & Oral Health ResearchersDespite some disparities, male & female applicants funded at same rates.NIDCR • August 19, 2019High-sugar intake worsens autoimmune disease in miceNIH Research Matters • August 27, 2019Study Identifies Protein Responsible for Mechanism Behind Bone LossUniversity of California...
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Extreme dipping: is the cardiovascular risk increased? An unsolved issueExtreme dipping (i.e. a marked blood pressure fall during night-time period) is an alteration of circadian blood pressure (BP) rhythm frequently observed in the setting of systemic hypertension as well as in the general population. Some reports have suggested that cardiovascular prognosis in extreme dippers (ED) is similar as in dippers, whereas other studies have documented either a better or worse prognosis in ED. Available...
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Editorial: Cerebrospinal fluid physiologyNo abstract availablePhysiology of cerebrospinal fluid circulationPurpose of review This article describes the physiology of cerebrospinal fluid (CSF). We review current evidence and new concepts relating to CSF physiology with respect to CSF secretion, circulation and resorption and we highlight key pathophysiological associations including the relationship between CSF and intracranial pressure. Recent findings CSF secretion occurs primarily via the choroid...
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The female adolescent breast: disorders of developmentPurpose of review This article will provide an overview on female breast development and focus on common abnormalities of growth, the emerging role of breast self-awareness, and discuss trends in the evaluation and treatment of the breast masses and disorders most often encountered in the female adolescent population. Recent findings Although the embryology of breast development is unchanged, data are emerging on the role of environmental factors...
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Monthly Extended-Release Risperidone (RBP-7000) in the Treatment of Schizophrenia: Results From the Phase 3 ProgramPurpose/Background The Phase 3 program for RBP-7000, a once-monthly subcutaneous (SC) extended-release risperidone formulation approved for treatment of schizophrenia, consisted of a double-blind placebo-controlled trial (previously reported) and a 52-week open-label study of monthly RBP-7000 120 mg. The primary objective of the open-label study was to evaluate the long-term safety and...
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Artificial Intelligence and Machine Learning in the Identification of Authentic and Fake Data PresentationNo abstract availableTextbooks in Plastic Surgery: Paper or Digital?No abstract availableFaces, the Frontiers of NormalityNo abstract availableGood Surgical IllustrationsNo abstract availableGutenberg's Spirit in Today's WorldNo abstract availableCraniosynostosis: A Reversible Pathology?The formation of the cranial sutures, in utero, occurs when the ossification of the skull bones reaches predestined...
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Subclinical hypothyroidism in pregnancyPurpose of review Subclinical hypothyroidism (SCH) is a common diagnosis among women of reproductive age. The importance of sufficient maternal thyroid supply during pregnancy is well known. Nevertheless, the effects of SCH during pregnancy and the efficacy of its treatment on maternofetal outcomes are not well established. This review discusses the recent evidence on SCH in pregnancy and how this evidence is reflected in current clinical care. Recent findings...
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Dysbiosis of the Duodenal Mucosal Microbiota Is Associated With Increased Small Intestinal Permeability in Chronic Liver DiseaseOBJECTIVES: Chronic liver disease (CLD) is associated with both alterations of the stool microbiota and increased small intestinal permeability. However, little is known about the role of the small intestinal mucosa-associated microbiota (MAM) in CLD. The aim of this study was to evaluate the relationship between the duodenal MAM and both small intestinal permeability and...
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Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancerObjective To identify additional genetic variants beyond those observed in a previous genome-wide association study (GWAS) in women treated on the MA.27 clinical trial in which women were randomized to 5 years of adjuvant therapy with anastrozole or exemestane. Patients and methods We performed a matched case–control...
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Hereditary Cancer Risk Variants Found in Significant Subset of Metastatic Breast Cancer PatientsPublished on Aug 30, 2019 Court Upholds Illumina Victory in Scripps Research Institute Patent BattlePublished on Aug 30, 2019 Medulloblastoma Single-Cell Study Yields Tumor-Initiating Cell Population Containing Outcome CluesPublished on Aug 30, 2019 In Brief This Week: Invitae, Agilent, Biovica, and MorePublished on Aug 30, 2019 People in the News: Rowan Chapman, Garret Hampton, Eric Dishman, MorePublished...
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Sociedad Iberoamericana de Información Científica (SIIC),ARTÍCULOS DE FUENTES SELECCIONADASLos artículos de fuentes seleccionadas son resumidos en castellano por el Comité de Redacción Científica de SIIC.Violeth Margarett Vásquez FonsecaRELACIÓN ENTRE EL BURNOUT Y LA SATISFACCIÓN LABORAL EN PROFESIONALES DE LA SALUDEl objetivo del estudio es analizar la relación entre el grado de satisfacción laboral y el burnout en profesionales del Hospital Clínico Herminda Martín. El 91% de la muestra tiene riesgo...
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Pakistan Journal of Biological Sciences - Current IssueIn vitro Anticancer Activity of Quinoa and Safflower Seeds and Their Preventive Effects on Non-alcoholic Fatty LiverAssociation of Perforin and Granzyme-B Levels with Hyperandrogenism in Polycystic Ovary Syndrome: A Case-Control StudyIsometric Versus Aerobic Training Effects on Vascular Adaptation in Patients with Type 2 DiabetesIn vitro Anticancer Activity of Quinoa and Safflower Seeds and Their Preventive Effects on Non-alcoholic Fatty LiverPosted:Background...
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Demographics, Psychological Distress, and Pain From Pressure InjuryBackground There is a knowledge gap regarding factors that influence the intensity of pain associated with pressure injuries. Objectives We examined the influence of age, gender, race, and comorbidity on the relationships between pressure injuries, psychological distress, and pain intensity in hospitalized adults. Methods This study was a cross-sectional, retrospective secondary analysis using data from a regional acute hospital's...
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Intraperitoneal hemorrhage during pregnancy and parturition: Case reports and literature reviewWe aim to investigate the diagnosis, treatment, and prognosis of intraperitoneal hemorrhage during pregnancy and parturition. Three cases with intraperitoneal hemorrhage during pregnancy and parturition admitted to our hospital from Jan. 2008 to Jan. 2018 were included in this study. One case showed fetal distress. Abdominal ultrasonography and abdominal CT showed pyoperitoneum in 2 cases. Abdominal puncture...
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Rohan R. Mahale, Anish Mehta, Aju Abraham John, Mahendra Javali, Mirza Masoom Abbas, andSrinivasa RangasettyAuthor information Article notes Copyright and License information DisclaimerDepartment of Neurology, Mathikere Sampangappa Ramaiah Medical College and Hospital, Bangalore, Karnataka, IndiaFor correspondence: Dr. Rohan R. Mahale, Department of Neurology, MS Ramaiah Medical College and Hospital, Bangalore - 560 054, Karnataka, India. E-mail: moc.liamg@38elahamnahorReceived 2015 Jan 13; Revised...
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Nine syndromeCorrection to: The effect of CA1 dopaminergic system on amnesia induced by harmane in miceUnfortunately, the second author name was incorrectly published in the original article. The complete correct name should read as follows.Bilateral stereotypy after unilateral cerebellar infarctionBilateral fronto-insular FLAIR hyperintensities: discussion on a case of new-onset refractory status epilepticusPosterior reversible encephalopathy syndrome caused by cerebral amyloid angiopathy-related...
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Increasing Medical Student Exposure to Interventional RadiologyCorrection To: Where is the Origin of the Last Normal Branch from Feeding Artery of Pulmonary Arteriovenous Malformations?On page 1852, the first sentence of the second paragraph "In all PAVMs, the mean diameter of the feeding artery was 7.24 ± 0.015 mm, and the mean maximum diameter of the sac was 19.10 ± 0.585 mm" should be corrected to read as follows:Transapical Coil Embolization of a Postsurgical Ascending Thoracic Aortic PseudoaneurysmAbstractAscending...
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The Impact of Hospital Costing Methods on Cost-Effectiveness Analysis: A Case Study'Tisagenlecleucel for the Treatment of Relapsed or Refractory B-cell Acute Lymphoblastic Leukaemia in People Aged up to 25 Years: An Evidence Review Group Perspective of a NICE Single Technology AppraisalAbstractAs part of the National Institute for Health and Care Excellence's (NICE's) Single Technology Appraisal (STA) process, Novartis submitted evidence on the clinical effectiveness and cost-effectiveness of tisagenlecleucel...
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Interactions between mitochondria and endoplasmic reticulum in demyelinated axonsAbstractDemyelination leads to axonal changes that involve the functions and dynamics of axonal mitochondria supporting metabolism and survival of axons. However, the changes in the physical interactions between mitochondria and endoplasmic reticulum, called mitochondria-associated membranes, are poorly understood in demyelinated axons. In this study, we investigated the three-dimensional ultrastructural changes in membrane...
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Accounting for study participants who are ineligible for linkage: a multiple imputation approach to analyzing the linked National Health and Nutrition Examination Survey and Centers for Medicare and Medicaid Services' Medicaid dataAbstractData from the National Health and Nutrition Examination Survey have been linked to the Center for Medicare and Medicaid Services' Medicaid Enrollment and Claims Files for the survey years 1999–2004. The linked data are produced by the National Center for Health...
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FOR YOUR PATIENTSOpioids Are Not Recommended but Often Prescribed for Migraine Across All Age Groups FOR YOUR PATIENTSObesity in Younger MS Patients Linked to Poor First-Line Therapy Response FOR YOUR PATIENTSShorter Times to Endovascular Reperfusion Therapy Lead to Better Outcomes for Acute Stroke Patients FOR YOUR PATIENTSNew Guidelines for Acute and Preventive Treatment of Pediatric Migraine: What You Should Know FOR YOUR PATIENTSPhysical Activity Moderates Amyloid-Beta Burden in Clinically Normal...
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Intravenous immunoglobulin for adjunctive treatment of severe infections in ICUsPurpose of review This review focuses on the emerging literature regarding the use of intravenous immunoglobulins (IVIg) in critically ill patients with severe infections. The aim is to provide an accessible summary of the most recent evidence of IVIg use in sepsis and septic shock and to help clinicians to understand why there is still equipoise regarding the potential benefit of this adjunctive therapy in this setting....
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The research odyssey of John Ross Jr: from trans-septal atrial catheterization, preload reserve, afterload mismatch to flow-function relationshipNo abstract availableThe role of physical activity in individuals with cardiovascular risk factors: an opinion paper from Italian Society of Cardiology-Emilia Romagna-Marche and SIC-SportRegular physical activity is a cornerstone in the prevention and treatment of atherosclerotic cardiovascular disease (CVD) due to its positive effects in reducing several...
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ERα-mediated alterations in circ_0023642 and miR-490-5p signaling suppress bladder cancer invasionLongxiang Wu, Mengda Zhang, Lin Qi, Xiongbing Zu, Yuan Li et al.Cell Death & Disease 2019 10: 10.1038/s41419-019-1827-3Abstract | Full TextThe Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancerMarina Kazantseva, Sunali Mehta, Ramona A. Eiholzer, Gregory Gimenez, Sara Bowie et al.Cell Death & Disease 2019 10: 10.1038/s41419-019-1861-1Abstract | Full...
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DermatologyVolume 181, Issue 3Pages: i-ix, 429-646, e57-e86September 2019Issue InformationIssue InformationPages: i-vi | First Published: 01 September 2019Editor's ChoiceEditor's ChoicePages: ix | First Published: 01 September 2019EDITORIALSEnduring support for the case reportJ.E. MellerioPages: 429-430 | First Published: 01 September 2019Pragmatic trials: lab meets bedsideG. Kirtschig, S. Lo, J. Batchelor, on behalf of the Clinical Trials Editorial Team of the British Journal of DermatologyPages:...
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Organizational Architecture, Ethical Culture, and Perceived Unethical Behavior Towards Customers: Evidence from Wholesale BankingAbstractIn this study, we propose and test a model of the effects of organizational ethical culture and organizational architecture on the perceived unethical behavior of employees towards customers. This study also examines the relationship between organizational ethical culture and moral acceptability judgment, hypothesizing that moral acceptability judgment is an important...
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Pediatric Radiology continuing medical education activityOlfactory bulb and olfactory tract abnormalities in acrocallosal syndrome and Greig cephalopolysyndactyly syndromeAbstractWe describe association of olfactory bulb and olfactory tract abnormalities in a child with acrocallosal syndrome caused by kinesin family membrane 7 (KIF7) mutation in sonic hedgehog pathway. The child also had fontanellar bone in the anterior fontanelle, short sagittal suture, sagittal synostosis, hippocampal malrotation...
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Editorial to the special issue on "Molecular Genetics of Developmental Eye Disorders"Phenotype–genotype correlations and emerging pathways in ocular anterior segment dysgenesisAbstractDisorders of the anterior segment of the eye encompass a variety of clinical presentations including aniridia, Axenfeld and Rieger anomalies, primary congenital glaucoma, Peters anomaly, as well as syndromal associations. These conditions have a significant impact on vision due to disruption of the visual axis, and...
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Adaptation to climate change and climate variability and its implications for household food security in KenyaAbstractClimate change and climate variability affect weather patterns and cause shifts in seasons with serious repercussions such as declining food production and productivity for communities and households in Kenya. To mitigate the negative impacts of climate change and variability, farming households have been encouraged to adopt different strategies such as new crop varieties, crop and...
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"Patient's lived experience"AbstractThis editorial presents a special issue gathering four contributions about the patient's lived experience in the context of deep-brain stimulation. It aims at clarifying the meaning of such an experience and its scope for medical practice, the health system and its legal frame.A non-ideal authenticity-based conceptualization of personal autonomyAbstractRespect for autonomy is a central moral principle in bioethics. The concept of autonomy can be construed in various...
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Analogical Cognition: an Insight into Word MeaningAbstractAnalogical cognition, extensively researched by Dedre Gentner and her colleagues over the past thirty five years, has been described as the core of human cognition, and it characterizes our use of many words. This research provides significant insight into the nature of word meaning, but it has been ignored by linguists and philosophers of language. I discuss some of the implications of the research for our account of word meaning. In particular,...
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Current status of cardiovascular surgery in Japan, 2015 and 2016, a report based on the Japan Cardiovascular Surgery Database. 3—Valvular heart surgeryIn the original publication of this article, the title was published incorrectly. The correct article title is given in this correction.Correction to: Successful adjustment for self-expanding metallic stent migration using a flexible bronchoscope with two biopsy forceps techniqueIn the original publication of the article, the corresponding author...
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Die wissenschaftlichen Beiträge und deren Auswahlverfahren für den 71. Kongress der Deutschen Gesellschaft für Urologie e. V. 2019Evaluation von Langzeiteffekten nach Chemoprävention des ProstatakarzinomsKosteneffizienz verschiedener Active-Surveillance-Strategien im Vergleich zu Watchful WaitingBvDU Kurz notiertAusbildung junger Assistenzärzte – eine wertvolle Investition in die Zukunft der UrologieLeitlinienadhärenzPhosphodiesteraseinhibitoren zur Behandlung des benignen ProstatasyndromsAUOMensch,...
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Mitochondrial Heteroplasmy in Marsh Frog ( Pelophylax ridibundus Pallas, 1771)AbstractThe population features of nuclear and mitochondrial genomes of P. ridibundus Pallas, 1771 and related species of green frogs from Nizhny Novgorod and Sverdlovsk oblasts were investigated for the first time. The existence of the R–E–L population system on the territory of Nizhny Novgorod oblast was confirmed. The presence of heteroplasmy was found in all examined samples of marsh frogs, as well as in hybrid, edible,...
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Glucagon-Like Peptide-1 Receptor Agonists in Type 2 Diabetes: Their Use and Differential FeaturesThe original version of this article unfortunately contained some mistakes. The corrected details are provided below:Correction to: Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel Na V 1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy VolunteersThe original version of this article unfortunately contained a mistake. A few entries were incorrect in Table 2.Safety,...
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Deep Neck Space Infections: A Case Series and Review of the Literature,Shivesh Maharaj, Sumaya Ahmed, Preba Pillayhttps://doi.org/10.1177/1179550619871274Article information AbstractDeep neck spaces are regions of loose connective tissue filling areas between the 3 layers of deep cervical fascia, namely, superficial, middle, and deep layers. The superficial layer is the investing layer, The pretracheal layer is the intermediate layer and the prevertebral layer is the deepest layer. Deep neck space...
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Delineation of the intratemporal facial nerve in a cadaveric specimen on diffusion tensor imaging using a 9.4 T magnetic resonance imaging scanner: a technical noteAbstractThe purpose of this study was to determine whether the intratemporal facial nerve could be delineated on 9.4 T magnetic resonance imaging (MRI) using T2-weighted and diffusion tensor imaging (DTI). DTI using a b value of 3000 and an isotropic resolution of 0.4 mm3 on a 9.4 T MRI scanner was performed on a whole-block celloidin-embedded...
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In Vitro Selection of DNA Aptamers for a Small-Molecule Porphyrin by Gold Nanoparticle-Based SELEXAbstractIn this study, a new strategy for the selection of aptamers against small-molecule target was established using gold nanoparticles (AuNPs) as the separation matrix and Zinc(II)-Protoporphyrin IX (ZnPPIX) as the target molecule without the immobilization step due to the absorption of ssDNA on AuNPs. The progress of the selection process was monitored by the recovery rate and the fluorescence enhancement...
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Onkologisches Outcome nach Notfallresektion vs. Stenting bei maligner linksseitiger KolonobstruktionErhalt vs. Resektion der Arteria colica sinistra im Rahmen der kolorektalen Karzinomchirurgie des linken HemikolonsLaparoskopische Leberresektion bei älteren PatientenFrühe oder späte Cholezystektomie bei milder biliärer akuter Pankreatitis?Intrathorakale FistelnChirurgische Versorgung tracheo-/bronchopleuraler Fisteln nach bronchoplastischer Resektion (Manschetten‑/Bifurkationsresektion)ZusammenfassungDie...
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Onkologisches Outcome nach Notfallresektion vs. Stenting bei maligner linksseitiger KolonobstruktionErhalt vs. Resektion der Arteria colica sinistra im Rahmen der kolorektalen Karzinomchirurgie des linken HemikolonsLaparoskopische Leberresektion bei älteren PatientenFrühe oder späte Cholezystektomie bei milder biliärer akuter Pankreatitis?Intrathorakale FistelnChirurgische Versorgung tracheo-/bronchopleuraler Fisteln nach bronchoplastischer Resektion (Manschetten‑/Bifurkationsresektion)ZusammenfassungDie...
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Data science ethical considerations: a systematic literature review and proposed project frameworkAbstractData science, and the related field of big data, is an emerging discipline involving the analysis of data to solve problems and develop insights. This rapidly growing domain promises many benefits to both consumers and businesses. However, the use of big data analytics can also introduce many ethical concerns, stemming from, for example, the possible loss of privacy or the harming of a sub-category...
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Simulator-based assessment of ankle arterial systolic blood pressure measurement skillsObjective Learning basic vascular examination is a complex process. Very few studies have focused on the ability to measure the arterial systolic blood pressure at the ankle (ASBPa). The aim of this study was to objectively assess the effects of a 1-h practical educational intervention on the ability to measure ASBPa among medical students. Methods A total of 27 medical students were prospectively recruited. Two...
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Impact of energy turnover on the regulation of glucose homeostasis in healthy subjectsFranziska Büsing, Franziska Anna Hägele, Alessa Nas, Mario Hasler, Manfred James Müller et al.Nutrition & Diabetes 2019 9: 10.1038/s41387-019-0089-6Abstract | Full TextREVIEW ARTICLETopInhibitory effects of pu-erh tea on alpha glucosidase and alpha amylase: a systemic reviewChiung-Ying Yang, Yea-Yin Yen, Kuang-Chen Hung, Shang-Wei Hsu, Shou-Jen Lan et al.Nutrition & Diabetes 2019 9: 10.1038/s41387-019-0092-yAbstract | Full...
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The Human Brain Can Create Structures in Up to 11 Dimensions,"We found a world that we had never imagined." Read more »Physicists Have Published Instructions For a DIY WormholeSome entirely theoretical components required.Read more »Scientists Break Down 5 of The Latest Diet Fads, And 2 Definitely Aren't RecommendedThe mono diet sounds unpleasant.Read more »Scientists Detected 2 Black Hole Mergers Just 21 Mins Apart, But It's Not What We HopedThis could have been something big.Read more »13 Strange...
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Effect of High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength: A Randomized Clinical TrialLauren A. Burt, PhD; Emma O. Billington, MD, FRCPC; Marianne S. Rose, PhD; et alJAMA PediatricsAssociation Between Maternal Fluoride Exposure During Pregnancy and IQ Scores in Offspring in CanadaRivka Green, MA; Bruce Lanphear, MD; Richard Hornung, PhD; et alJAMA Internal MedicineAssociation of Animal and Plant Protein Intake With All-Cause and Cause-Specific MortalitySanjeev Budhathoki, PhD;...
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Baseline serum levels of osteopontin predict clinical response to treatment with nivolumab in patients with non-small cell lung cancerAbstractTreatment with nivolumab improves survival and response rate in non-small cell lung cancer (NSCLC). Nevertheless, due to its high financial cost, identifying predictors of response to treatment has become an urgent need. Here, we focused on serum osteopontin (OPN), a pleiotropic protein overexpressed in lung cancer and involved in the immune response. A cohort...
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Capsule Commentary on Jetelina et al., Patient-Reported Barriers to Completing a Diagnostic Colonoscopy Following Abnormal Fecal Immunochemical Test among Uninsured PatientsCapsule Commentary on Homoya et al., Uncertainty as a Key Influence in the Decision to Admit Patients with Transient Ischemic AttackCapsule Commentary on Bond et al., Real-time Feedback in Pay-for-Performance: Does More Information Lead to Improvement?Abnormal Liver EnzymesCapsule Commentary on Zhang et al., Combined healthy lifestyle...
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Urinary Incontinence in Chronic Obstructive Pulmonary Disease: A Common Co-morbidity or a Typical Adverse Effect?AbstractUrinary incontinence (UI) is defined as a loss of bladder control and is characterized by the complaint of any involuntary leakage of urine. Evidence suggests that the prevalence of UI is higher in subjects with chronic obstructive pulmonary disease (COPD) than in age-matched controls in both sexes. UI is classified as stress, urge, and mixed, and has a considerable impact on quality...
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Differences in prevalence and associated factors between mild and severe vertebral fractures in Japanese men and women: the third survey of the ROAD studyAbstractVertebral fracture (VF) is a common osteoporotic fracture, while its epidemiology varies according to regions and ethnicities, little is known about it in Japan. Using whole-spine radiographs from a population-based cohort study, the Research on Osteoarthritis/Osteoporosis Against Disability study 3rd survey performed in 2012–2013, we estimated...
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Differences in prevalence and associated factors between mild and severe vertebral fractures in Japanese men and women: the third survey of the ROAD studyAbstractVertebral fracture (VF) is a common osteoporotic fracture, while its epidemiology varies according to regions and ethnicities, little is known about it in Japan. Using whole-spine radiographs from a population-based cohort study, the Research on Osteoarthritis/Osteoporosis Against Disability study 3rd survey performed in 2012–2013, we estimated...
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Late flowering in F 1 hybrid rice brought about by the complementary effect of quantitative trait lociAbstractLate flowering sometimes occurs in F1 hybrids between rice varieties (Oryza sativa L.), although the parental varieties show similar days-to-flowering (DTF). The genetic architecture prompting the occurrence of such late flowering is poorly understood. To clarify the genetic architecture of late flowering in F1 hybrids from a cross between rice varieties, 'Koshihikari' and 'IR64', we performed...
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Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variantsIn the original publication the grant number is incorrectly published. The correct grant number should be read as "17140901600". The corrected contents are provided in this correction article. This work was partially supported by grants from the National Natural Science Foundation of China (Nos. 81670470 and 81600149), a grant from the Shanghai Municipal Commission for...
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Mammalian Target of Rapamycin 2 (MTOR2) and C-MYC Modulate Glucosamine-6-Phosphate Synthesis in Glioblastoma (GBM) Cells Through Glutamine: Fructose-6-Phosphate Aminotransferase 1 (GFAT1)The original version of this article unfortunately contained an error in author group. The authors Yi-Xiang See, Xin Chen, Zi-Kai Chen and Ze-Bin Huang were inadvertently included in the article.Expression of ConcernIn Memoriam: Horst Grobecker (1934–2019)MicroRNAs are Necessary for BMP-7-induced Dendritic Growth...
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Association of plasma folate, vitamin B12 levels, and arsenic methylation capacity with developmental delay in preschool children in TaiwanAbstractDevelopmental delay has been associated with inefficient arsenic methylation capacity in preschool children. Folate and vitamin B12 are important nutrients that produce s-adenosylmethionine during single-carbon metabolism and provide methyl groups for arsenic methylation. The aim of the present study was to explore whether plasma folate and vitamin B12...
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Accuracy and Reliability of Multiphase CTA Perfusion for Identifying Ischemic Core Correction to:...
Accuracy and Reliability of Multiphase CTA Perfusion for Identifying Ischemic CoreCorrection to:Clin Neuroradiol 2018https://doi.org/10.1007/s00062-018-0717-xUnfortunately, the author list of the original version of this article contains a mistake. The middle name of the author "Rani Gupta Sah" was erroneously tagged as part of the surname in the article's metadata.This mistakeInformationNeuroimaging of Intracranial Perfusion and the Clinical Diagnosis of Brain Death: Setting the Gold Standard in...
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In the Shoes of a Child with AutismA Blue Eyed Girl with Hyperactivity: Look in to the Eyes and Heart!Book ReviewNews in BriefLevetiracetam in Neonatal seizuresRisk Stratification for Acute Kidney Injury in Critically-ill ChildrenViolence Against DoctorsRelationship of Leisure Time Activities and Psychological Distress in School ChildrenAbstractThis questionnaire study on 400 school children found that severe psychological distress using the K 10 scale was seen in 38 (9.5%), and 162 (40.5%) had less...
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SPECT/CT imaging of apoptosis in aortic aneurysm with radiolabeled duramycinThe original version of this article unfortunately contains errors in Figure 4. An incorrect Figure 4D is published which is actually a repetition of Figure 2C (i.e., apoptosis rate in control vs. H2O2-treated group). The correct Figure 4D should be the aortic diameter of control vs. experimental groups. Also, the order of part figures (a\b\c\d) in Figure 4E is incorrect. The correct Figure 4 is given below.Inhibition of...
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Overnight sleep benefits both neutral and negative direct associative and relational memoryAbstractStrong evidence suggests that sleep plays a role in memory consolidation, which involves both stabilizing memory into long-term storage as well as integrating new information into existing stores. The current study investigated consolidation, across a day of wakefulness or night of sleep, of emotional and neutral directly learned visual paired associates (A-B/B-C pairs) as well as formation of memory...
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A mathematical modelling approach for managing sudden disturbances in a three-tier manufacturing supply chainAbstractThis paper aims to develop a recovery planning approach in a three-tier manufacturing supply chain, which has a single supplier, manufacturer, and retailer under an imperfect production environment, in which we consider three types of sudden disturbances: demand fluctuation, and disruptions to production and raw material supply, which are not known in advance. Firstly, a mathematical...
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Predicting (variability of) context effects in language comprehensionAbstractPredicting variability in context effects is a timely enterprise considering that psycho- and neurolinguistic research has assessed how language processing depends on the perceived context, the body, and long-term linguistic knowledge of the language user. The current evidence suggests that some context effects may be systematically more robust than others and that language user characteristics are an influential modulator...
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Recent Advances in Pharmacological Treatments of Adult DermatomyositisAbstractPurpose of the ReviewDermatomyositis (DM) is an uncommon autoimmune disease that primarily affects the skin, muscle, and/or lungs, and remains a therapeutic challenge. We discuss recent studies evaluating efficacy of conventional treatments for clinically amyopathic DM (CADM), DM-associated interstitial lung (ILD) disease, and classic DM (CDM). We highlight several emerging new therapies with a focus on clinical trials,...
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Perioperative Medicine,Nitrous Oxide Impairs Axon Regeneration after Nervous System Injury in Male RatsKrista J. Stewart, M.D.; Bermans J. Iskandar, M.D.; Brenton M. Meier, M.D.; Elias B. Rizk, M.D.; Nithya Hariharan, M.D.; Joyce Koueik, M.D., M.S.; Adin-Christian Andrei, Ph.D.; Kirk J. Hogan, M.D., J.D.Anesthesiology Published online August 30, 2019. doi:10.1097/ALN.0000000000002906Accuracy of Physical Function Questions to Predict Moderate-Vigorous Physical Activity as Measured by Hip AccelerometryDaniel...
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Inflammatory response and recurrence after minimally invasive esophagectomyAbstractPurposeEsophagectomy for esophageal cancer is a very invasive surgery that induces an intense systemic inflammatory response. Postoperative infectious complications worsen survival after esophagectomy through inflammatory responses, and this study aimed to investigate the impact of the response on disease recurrence.MethodsWe assessed 230 patients who underwent curative minimally invasive esophagectomy for esophageal...
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Optimization of Adsorption for the Removal of Cadmium from Aqueous Solution Using Turkish Coffee GroundsAbstractIn this study, the effectiveness of the use of spent Turkish coffee grounds as an adsorbent in the treatment of water polluted with cadmium (Cd) ions through adsorption was investigated. The change in adsorption efficiency (%) with independent variable parameters was planned using the Box–Behnken experimental design method, which is a subset of the response surface methodology (RSM), and...
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The Psychology of Internet Fraud Victimisation: a Systematic ReviewAbstractExisting theories of fraud provide some insight into how criminals target and exploit people in the online environment; whilst reference to psychological explanations is common, the actual use of established behavioural theories and/or methods in these studies is often limited. In particular, there is less understanding of why certain people/demographics are likely to respond to fraudulent communications. This systematic review...
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Fase final de la validación transcultural al español de la escala Hair Specific Skindex-29: sensibilidad al cambio y correlación con la escala SF-12Publication date: Available online 29 August 2019Source: Actas Dermo-SifiliográficasAuthor(s): A. Guerra-Tapia, A. Buendía-Eisman, J. Ferrando Barbera, en representación del grupo de validación Hair Specific Skindex-29, Juan Ferrando Barbera, Agustín Buendía Eisman, Aurora Guerra Tapia, Ana Garayalde Perurena, Yolanda Juárez Casado, Dolores Otero Tejero,...
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Does radioactive iodine therapy for Graves' disease cause cancer?Is obesity a risk factor for thyroid cancer?Does bariatric surgery change levothyroxine dose requirements?Are calcitonin measurements helpful in following patients with medullary thyroid cancer after surgery?Can cancer drugs make radioactive iodine-resistant thyroid cancer responsive to radioactive iodine again?How well do current molecular marker tests identify benign nodules that have indeterminate biopsy results?CLINICAL THYROIDOLOGY...
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Contact DermatitisAccepted ArticlesAccepted, unedited articles published online and citable. The final edited and typeset Version of Record will appear in the future.ORIGINAL ARTICLESPositive change in hand care habits using therapeutic patient education in chronic hand eczemaMarie Tauber, Siham Lourari, Emilie Bérard, Emmanuel Questel, Daniel Redoules, Françoise Giordano‐Labadie, Michel Simon, Paul CarleFirst Published: 28 August 2019CONTACT POINTSAllergic contact dermatitis from triethanolamine...
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Vascular Endothelial Growth Factor Protects CD200-Rich and CD34-Positive Hair Follicle Stem Cells Against Androgen-Induced Apoptosis Through the Phosphoinositide 3-Kinase/Akt Pathway in Patients With Androgenic Alopecia,Zhang, Xuesong MD*; Zhou, Dongmei MD*,†; Ma, Tengfei MD*; Liu, Qingquan MD*,†Dermatologic Surgery: August 30, 2019 - Volume Publish Ahead of Print - Issue - pdoi: 10.1097/DSS.0000000000002091Original Article: PDF OnlyBUYPAPAbstractAuthor InformationArticle MetricsBACKGROUND 5α-DHT...
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Sensory Integration and Functional Reaching in Children With Rett Syndrome/Rett-Related DisordersShow lessWendy Drobnyk, Karen Rocco, Sara Davidson, Susan Bruce, Fang Zhang, Stephen B Soumerai First Published August 26, 2019 Research Article https://doi.org/10.1177/1179556519871952Article information Article has an altmetric score of 3 Open Access Creative Commons Attribution, Non Commercial 4.0 LicenseAbstractBackground:The loss of functional hand skills is a primary characteristic of Rett syndrome....
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Allergy & Rhinology Early ViewOnline Version of Record before inclusion in an issueOriginal ArticlesManuka honey sinus irrigations in recalcitrant chronic rhinosinusitis: phase 1 randomized, single‐blinded, placebo‐controlled trialMian Li Ooi MBBS, Arvind Jothin MBBS, Catherine Bennett BMedSc, Eng H. Ooi MBBS, PhD, FRACS, Sarah Vreugde MD, PhD, Alkis J. Psaltis MBBS, PhD, FRACS, Peter‐John Wormald MD, FRACSVersion of Record online: 28 August 2019Original ArticlesAdvanced age adversely affects...
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