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Related ArticlesEmerging therapeutic potential of anti-psychotic drugs in the management of human glioma: A comprehensive review. Oncotarget. 2019 Jun 11;10(39):3952-3977 Authors: Kamarudin MNA, Parhar I Abstract Despite numerous advancements in the last decade, human gliomas such as astrocytoma and glioblastoma multiforme have the worst prognoses among all cancers. Anti-psychotic drugs are commonly prescribed to treat mental disorders among cancer patients,...
Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas.
Related ArticlesFunctional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas. Oncotarget. 2019 Jun 11;10(39):3939-3951 Authors: Delacruz RGC, Sandoval IT, Chang K, Miller BN, Reyes-Uribe L, Borras E, Lynch PM, Taggart MW, Hawk ET, Vilar E, Jones DA Abstract Germline mutations in the tumor suppressor Adenomatous Polyposis Coli (APC) define Familial Adenomatous Polyposis (FAP), the genetic predisposition to developing...
Related ArticlesFree episomal and integrated HBV DNA in HBsAg-negative patients with intrahepatic cholangiocarcinoma. Oncotarget. 2019 Jun 11;10(39):3931-3938 Authors: Pollicino T, Musolino C, Saitta C, Tripodi G, Lanza M, Raffa G, Tocco FCD, Raggi C, Bragazzi MC, Barbera A, Navarra G, Invernizzi P, Alvaro D, Raimondo G Abstract There is evidence that chronic hepatitis B virus (HBV) infection is associated with an increased risk of intrahepatic cholangiocarcinoma...
Related ArticlesSpontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall. Oncotarget. 2019 Jun 11;10(39):3924-3930 Authors: Moyer AM, Yu J, Sinnwell JP, Dockter TJ, Suman VJ, Weinshilboum RM, Boughey JC, Goetz MP, Visscher DW, Wang L Abstract Patient-derived xenografts (PDX) are generated in immune deficient mice and demonstrate histologic and molecular features similar to their corresponding human tumors. However,...
Related ArticlesA priori prediction of breast tumour response to chemotherapy using quantitative ultrasound imaging and artificial neural networks. Oncotarget. 2019 Jun 11;10(39):3910-3923 Authors: Tadayyon H, Gangeh M, Sannachi L, Trudeau M, Pritchard K, Ghandi S, Eisen A, Look-Hong N, Holloway C, Wright F, Rakovitch E, Vesprini D, Tran WT, Curpen B, Czarnota G Abstract We demonstrate the clinical utility of combining quantitative ultrasound (QUS) imaging...
Related ArticlesPrioritization of metabolic genes as novel therapeutic targets in estrogen-receptor negative breast tumors using multi-omics data and text mining. Oncotarget. 2019 Jun 11;10(39):3894-3909 Authors: Barupal DK, Gao B, Budczies J, Phinney BS, Perroud B, Denkert C, Fiehn O Abstract Estrogen-receptor negative (ERneg) breast cancer is an aggressive breast cancer subtype in the need for new therapeutic options. We have analyzed metabolomics,...
Related ArticlesPlasma lncRNA expression profile as a prognostic tool in BRAF-mutant metastatic melanoma patients treated with BRAF inhibitor. Oncotarget. 2019 Jun 11;10(39):3879-3893 Authors: Kolenda T, Rutkowski P, Michalak M, Kozak K, Guglas K, Ryś M, Galus Ł, Woźniak S, Ługowska I, Gos A, Teresiak A, Mackiewicz A, Lamperska K, Mackiewicz J Abstract Long non-coding RNAs (lncRNA) are dysregulated in many cancer types. Abnormal baseline levels of these...
Related ArticlesInvestigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma. Oncotarget. 2019 Jun 11;10(39):3865-3878 Authors: Patel PO, Pishas KI, Taslim C, Selich-Anderson J, Theisen ER, Lessnick SL Abstract Ewing sarcoma is the second most common solid bone malignancy diagnosed in pediatric and young adolescent populations. Despite aggressive multi-modal treatment strategies, 5-year event-free survival remains at 75% for patients with...
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Related ArticlesMultidisciplinary palliation for unresectable recurrent rectal cancer: hypoxic pelvic perfusion with mitomycin C and oxaliplatin in patients progressing after systemic chemotherapy and radiotherapy, a retrospective cohort study. Oncotarget. 2019 Jun 11;10(39):1-13 Authors: Guadagni S, Fiorentini G, Mambrini A, Masedu F, Valenti M, Mackay AR, Sarti D, Ricevuto E, Clementi M, Catarci M, Lazzarin G, Bruera G Abstract Background: Innovative...
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