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Monday, September 25, 2017

GSE104122 IMM_IL-17RC_KO mice_exp1

Contributors : Julie Carman ; Wen-Pin Yang ; Jun Zhu ; Jarod Zepp
Series Type : Expression profiling by array
Organism : Mus musculus

This study identifies a novel mechanism linking IL-17A with colon tissue repair and tumor development. Abrogation of IL-17A signaling mice attenuated tissue repair of DSS-induced damage in colon epithelium and markedly reduced tumor development in AOM/DSS model of colitis-associated cancer. The goal of these studies is to identify genes associated with IL-17RC deficiency during AOM-DSS induced tumorigenesis



from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2yo5nPg

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