Recent advances in formal C(sp2)-H functionalization of aldehyde-derived N,N-dialkylhydrazones (substitution at azomethine carbon atom) are highlighted with a focus on radical-mediated processes that open up new opportunities for C-C bond formation such as alkylation reactions using hypervalent iodonium reagents or polyhaloalkanes, as well as for carbon-heteroatom bond formation (C-N, C-P). Cascade sequences based on these reactions, and leading to (hetero)cyclic frameworks, are also discussed.
from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2qK4Qbw
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