1
"Can A Prescribed Walking Program With or Without Monitoring Impact Dizziness in the Older Adults?" Behavioral: VRWP Group Behavioral: VRW Group Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment modified Clinical Test of Sensory Integration for Balance (mCTSIB) Timed Up and Go (TUG) test Dynamic Gait Index (and 3 more...) Florida Hospital East Orlando Orlando, Florida, United States Florida Hospital Winter Park Winter Park, Florida, United States 2
Acceptance and Commitment Therapy With Vestibular Rehabilitation for ChronicDizziness Behavioral: ACT with VR Behavioral: self-treatment VR Other: clinical management Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Handicap due to dizziness Response rate Remission rate (and 7 more...) Nagoya City University Nagoya, Aichi, Japan 3
Vestibular Rehabilitation andDizziness Behavioral: standard balance rehabilitation Behavioral: gaze stability Behavioral: Control Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Outcomes Assessor) Primary Purpose: Treatment Visual Analog Scale - Head Movement Visual Analog Scale - Disequilibrium Dynamic Gait Index (and 2 more...) Atlanta VA Medical and Rehab Center, Decatur, GA Decatur, Georgia, United States Mountain Home VA Medical Center James H. Quillen VA Medical Center, Mountain Home, TN Mountain Home, Tennessee, United States 4
Tailored Care for SomatoformVertigo /Dizziness Somatoform Vertigo /Dizziness Behavioral: SVD-tailored Integrative Psychotherapy (IPT) Behavioral: Self-help group (SHG) Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Vertigo-related quality of life Generic quality of life Severity of vertigo (and 4 more...) 5
Herbal Medication (Gongjin-dan) for Chronic Dizziness Drug: Gongjin-Dan Drug: Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Investigator, Outcomes Assessor) Primary Purpose: Treatment Dizziness Handicap Inventory (DHI), change between baseline and endpoint Dizziness Handicap Inventory (DHI), change between baseline and day 14, day 28, day 42 Mean Vertigo Score (MVS), changes between baseline and day 28 and day 56 (and 10 more...) Semyung University Korean Medicine Hospital Chungju, Chungcheongbuk-do, Korea, Republic of Dongguk University Ilsan Oriental Hospital Goyang, Gyeonggi-do, Korea, Republic of Pusan National University Korean Medicine Hospital Yangsan, Gyeongsangnam-do, Korea, Republic of Kyung Hee University Korean Medicine Hospital Seoul, Special Seoul City, Korea, Republic of 6
Chuna Manual Therapy for Cervicogenic Dizziness Procedure: Chuna Manual Therapy Procedure: Usual care Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment Change from baseline Dizziness Handicap Inventory (DHI) score at week 6 Change from baseline Dizziness Handicap Inventory (DHI) score at week 3 Changes from baseline Mean Vertigo Score (MVS) at each measurement week (and 8 more...) Kyung Hee University Korean Medicine Hospital Seoul, Special Seoul City, Korea, Republic of Kyung Hee University Korean Medicine Hospital at Gangdong Seoul, Korea, Republic of 7
A Trial of Booklet Based Self Management of Dizziness Behavioral: Self-treatment booklet Behavioral: Remote telephone support Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Investigator) Primary Purpose: Treatment Self-reported measures of dizziness Quality of life effects of dizziness Hampshire PCT and Berkshire PCT Southampton, United Kingdom 8
Wii Balance Board inDizziness Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Supportive Care 9
Vestibular Rehabilitation andDizziness in Geriatric Patients Behavioral: Vestibular rehabilitation Behavioral: Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Participant) Primary Purpose: Treatment Dynamic Gait Index Dynamic Visual Acuity Atlanta VA Medical and Rehab Center, Decatur Decatur, Georgia, United States 10
Is The Sudden Onset ofDizziness A Symptom of Acute Liver Dysfunction? Observational Model: Case Control Time Perspective: Prospective LFTs serum levels by biochemical method ALT, AST, ALP, GGT, total bilirubin, conjugated bilirubin, albumin, INR, aPTT, and Platelet count (PC) The cost calculation for the LFTs Adiyaman University Research Hospital Adiyaman, Central, Turkey 11
Study to Assess the Efficacy and Safety of SpotOn Specs™ for the Treatment of Chronic Dizziness Device: SpotOn's corrective elements for dizziness Device: Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Investigator, Outcomes Assessor) Primary Purpose: Treatment Dizziness Handicap Inventory (DHI) Vertigo Symptom Scale-Short Form Visual Vertigo Analog Scale (VVAS) (and 4 more...) Dept Neurology, Meir Medical Center Kfar Saba, Israel 12
Pilot Project on External Vestibular Prosthesis in Chronic Subjective Dizziness Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Significant difference (p<0.05) in sway magnitude fore and aft / right left between CSD patients and the age and gender matched controls Visual Analog Scales Mayo Clinic Rochester, Minnesota, United States 13
Vestibular Rehabilitation for Strokepatients WithDizziness Other: Vestibular rehabilitation Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Investigator) Primary Purpose: Treatment The Activities-specific Balance Confidence Scale EuroQol 5D The Berg Balance Scale Lund University Malmö, Sweden 14
Efficacy of a Transcranial Vibrating System for Minimizing Dizziness During Caloric Testing Vestibular Function Tests Dizziness Device: Efficacy of transcranial vibrating system on mitigating dizziness and nausea during caloric testing Allocation: Non-Randomized Intervention Model: Sequential Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Prevention Nausea and dizziness Vestibular testing outcomes University of Maryland Baltimore, Maryland, United States 15
The Relationship BetweenDizziness and Neck Pain Dizziness Vertigo Neck Pain Observational Model: Cohort Time Perspective: Prospective Difference between Groups in the Dizziness Handicap Inventory (DHI) Difference betwee Groups in the Neck Disability Index (NDI) Correlation between Posturography and neck pain Haukeland University Hospital Bergen, Norway 16
Traction Manipulation of Upper Cervical Spine on Cervicogenic Dizziness Other: Intervention Group Other: Control Group Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment Change of baseline in Dizziness Intensity (100mm VAS) at 1 week and 1 month Change of baseline in range of motion of cervical spine change (Tool: Cervical range of motion) Change of baseline in upper cervical spine range of motion (Tool: Cervical range of motion) Change of baseline in dizziness Handicap Inventory (questionnaire) Unidad de Investgación en Fisioterapia. Universidad de Zaragoza Zaragoza, Spain 17
To Study the Characteristics of Different Types of Vertigo in Patients Attending the Ear Nose & Throat (ENT) Clinics. Observational Model: Cohort Time Perspective: Prospective Characteristics (Different Types) of dizziness Quality of Life (QoL) of patients at baselines Management of vertigo currently in practice QoL of patients post treatment Research facility ID ORG-001139 Hyderabad, Pakistan Research facility ID ORG-001053 Islamabad, Pakistan Research facility ID ORG-001070 Karachi, Pakistan (and 8 more...) 18
Acute Video-oculography forVertigo in Emergency Rooms for Rapid Triage (AVERT) Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Diagnostic Six-Category Diagnosis Accuracy (all, VRT vs. SOC) Index Visit Total Diagnostic Utilization Costs (all, VRT vs. SOC) Odds of Short-Term Serious Medical Events (SMEs) after Misdiagnosis (SOC arm only, correct vs. incorrect diagnoses) (and 7 more...) University of Illinois Peoria, Illinois, United States University of Michigan Ann Arbor, Michigan, United States 19
Verapamil vs. Sertraline for Vestibular Migraine & Chronic Subjective Dizziness Vestibular Migraine Chronic Subjective Dizziness Drug: Verapamil Drug: Sertraline Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Diagnostic 2-week Average Rating of Severity of Headache from the Daily Symptom Diaries 2-week Average Rating of Severity of Dizziness/Unsteadiness from the Daily Symptom Diaries 2-week Average Rating of Sensitivity to Motion of Self from the Daily Symptom Diaries (and 5 more...) Mayo Clinic Rochester, Minnesota, United States 20
Effectiveness of Early Physical Therapy Intervention for Patients With Dizziness After a Sports-Related Concussion Brain Concussion Dizziness Other: Physical Therapy Treatment Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Care Provider, Outcomes Assessor) Primary Purpose: Treatment Symptom recovery as measured by the Post Concussion Symptom (PCS) Score Return to Play (RTP) Change Score of Functional Gait Assessment (and 2 more...) Walsh University North Canton, Ohio, United States 21
Efficacy and Safety of Acupuncture for Dizziness and Vertigo in Emergency Department: a Clinical Control Trial Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Supportive Care Visual Analog Scale (VAS) of dizziness 22
Trental for the Treatment ofVertigo /Dizziness /Imbalance Drug: Pentoxifylline Drug: Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Effect of Trental as assessed by Quality of Life questionnaire University of Missouri Columbia, Missouri, United States 23
Assessment and Treatment of Patients With Long-termDizziness in Primary Care Dizziness Vertigo Vestibular Neuritis Behavioral: BI + VR + CBT Behavioral: BI + phone calls Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment Dizziness Handicap Inventory (DHI) 6 m walking test Vertigo symptom scale (VSS-SF) (and 17 more...) Bergen University College Bergen, Norway 24
The Effects of Vestibular Rehabilitation Therapy Supported With Virtual Reality in the Elderly Patients WithDizziness Dizziness Vestibular Rehabilitation Virtual Reality Other: Vestibular Rehabilitation supported with Virtual Reality Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment Vertigo Symptom Scale (Short form) Dizziness Handicap Inventory Berg Balance Test (and 5 more...) Pamukkale University Faculty of Medicine Denizli, Turkey 25
Effectiveness of Betaserc® (Betahistine Dihydrochloride) in Patients With VestibularVertigo in Routine Practice Time Perspective: Prospective Scale for Vestibular Vertigo Severity Level and Clinical Response Evaluation (SVVSLCRE) Change of the Patient's Clinical Conditions of Vestibular Vertigo From Baseline to the End of Observational Treatment Period Change of Vestibular Vertigo Attacks Frequency From Baseline to the End of Observational Treatment Period (and 5 more...) Site reference ID 89414 Belgorod, Russian Federation Research facility ID ORG-000838 Irkutsk, Russian Federation Site reference ID 89433 Kazan, Russian Federation (and 21 more...) 26
Non Inferiority of Meclin® (Meclizine Chlorhydrate) Versus Dramin® (Dimenhydrinate) in Control of Acute Vertigo Symptoms From Peripheral Origin Drug: Meclizine Drug: Dimenhydrinate Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment Vertigo Score (VS) Quality of Life Questionnaire DHI - Dizziness Handicap Inventory, validated for the Brazilian population Clinilive Maringá, Paraná, Brazil Irmandade da Santa Casa de Misericórdia de São Paulo São Paulo, SP, Brazil Alergoalpha Barueri, São Paulo, Brazil (and 4 more...) 27
PDCN for Treatment of Cervical Vertigo Procedure: percutaneous disc decompression with coblation nucleoplasty Procedure: Manual Therapy (SNAGs plus PJMs) Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Change of baseline in Dizziness Intensity Dizziness frequency (rated between o (none) and 5 (>once/day)) Change in Dizziness Handicap Index (DHI) Score (and 8 more...) the Third Affiliated Hospital of Sun Yat-Sen University Guangzhou, Guangdong, China 28
Diagnosis Of Vertigo With New Imaging Device: Functional MRI imaging Observational Model: Case Control Time Perspective: Retrospective Activation of target sites on the functional MRI images during the vestibular response Differences in the fiber tracking of central nervous system specifically involved in the vestibular response 29
Evidence Based Best Care Practice for Benign Paroxysmal PositionalVertigo Benign Paroxysmal Positional Vertigo Allocation: Randomized Intervention Model: Crossover Assignment Masking: None (Open Label) Primary Purpose: Health Services Research Likelihood of Receiving a BPPV Care Process Outpatient Referral to a BPPV Provider 90-day Cumulative Incidence of Stroke 30
Comparison of Efficacy Between Piracetam and Dimenhydrinate in Patients With Peripheral Vertigo Drug: Administration of 100 mg dimenhydrinate intravenous Drug: 2 g piracetam intravenous Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Care Provider) Primary Purpose: Treatment Change in numeric rating scale Kocaeli University Kocaeli, Turkey 31
A Clinical Trial To Evaluate Efficacy And Safety Of Levophencynonate Hydrochloride In Patient WithVertigo Drug: Levophencynonate Hydrochloric Drug: Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment The duration of vertigo Vertigo severity improved(VAS score) Nerve function improved(NIHSS/MRS score) Renji Hospital Shanghai Jiaotong University School of Medicine Shanghai, Shanghai, China 32
Efficacy of Postural Restriction in Treating Benign Paroxysmal PositionalVertigo Benign Paroxysmal Positional Vertigo Behavioral: Postural restriction Behavioral: Normal daily activity Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment The Dix-Hallpike test Resolution time Medication needed (and 2 more...) Yuvatiya Plodpoai Hatyai, Songkhla, Thailand 33
The Effect of Obstructive Sleep Apnea Treatment onDizziness , Vertigo Sleep Apnea Dizziness Vertigo Other: Treatment of Obstructive Sleep Apnea-CPAP/BiPAP etc./Diet/surgery/life style changes Observational Model: Cohort Time Perspective: Prospective Dizziness Handicap Inventory Score Romberg on foam test Wolfson Medical Centre Holon, Israel 34
AM-125 in the Treatment of Acute Peripheral Vertigo Following Vestibular Schwannoma Resection Drug: Intranasal Drug Drug: Oral Tablet Other: Intranasal Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment Improvement of time standing on foam (eyes closed) Improvement in tandem Romberg test (eyes closed) 35
Comparison of Home-Based Exercise on the Posterior Canal Benign Paroxysmal Positional Vertigo Symptoms Benign Paroxysmal Positional Vertigo Other: Self Epley Manoeuvre Other: Brandt-Daroff Exercise Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Investigator) Primary Purpose: Treatment Vertigo resolution Conversion of a positive to negative Dix-Hallpike test Vertigo intensity Dizziness Handicap Inventory 36
Vestibular Evoked Myogenic Potentials in Benign Paroxysmal PositionalVertigo (VEMP in BPPV) Observational Model: Cohort Time Perspective: Prospective Number of subjects with normal VEMP response Number of subjects with recurrent BPPV in whom VEMP response was pathological Otoneurology Unit, Lin Medical Center, 35 Rotchild Avenue Haifa, Israel 37
Visual Feedback Goggle for Positional Vertigo Treatment Positional Vertigo Vertigo Device: Goggle with 20 degree error Device: Optimized Goggle Allocation: Randomized Intervention Model: Crossover Assignment Masking: Single (Participant) Primary Purpose: Treatment Symptom Relief Speed (SRS): defined as the number of days post-treatment until dizziness symptoms improve to category 5 (70-100% improvement from baseline). Symptom Relief Completeness (SRC): defined as the highest level (on the ordinal scale) of improvement attained during the allotted seven-day time period. Jay Farrior, MD Tampa, Florida, United States Debra Cooke, PH.D. Kansas City, Missouri, United States Mitchell Schwaber, MD Nashville, Tennessee, United States 38
Otolith Dysfunction Behavioral: Gaze stability exercises Behavioral: Centrifugation Behavioral: Balance rehabilitation Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment change in static subjective visual vertical change in symptom intensity change in sensory organization test (and 2 more...) Mountain Home VA Medical Center James H. Quillen VA Medical Center, Mountain Home, TN Mountain Home, Tennessee, United States 39
The Use of Virtual Reality for the Treatment of VisualVertigo . Treatment of Visual Vertigo Other: Virtual environment with fast moving objects Other: Virtual environment with no movement Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Participant) Primary Purpose: Treatment Change in scoring on the Situational Characteristic Questionnaire Change in scoring on the PHQ-9 Questionnaire from week one to six Change in scoring on the GAD-7 Questionnaire from week one to six Royal Hallamshire Hospital Sheffield, South Yorkshire, United Kingdom 40
Promethazine vs. Lorazepam for Treatment of Vertigo Drug: Promethazine Drug: Lorazepam Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment Mean change in vertigo intensity. Efficacy and Safety outcome measures (nausea change-second dose-adverse events). Department of Neurology, Emam Hossein Hospital Tehran, Nezam Abad, Iran, Islamic Republic of 41
Efficacy of a Mechanical Chair for Treatment of Benign Paroxysmal PositionalVertigo (BPPV) Vertigo Benign Paroxysmal Positional Vertigo Other: Standard Repositioning Other: Mechanical Chair Repositioning Other: Sham Treatment Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Dix-Hallpike Test Roll Test Dizziness Handicap Inventory Percent Dizziness is Improved Vanderbilt University Medical Center Nashville, Tennessee, United States 42
Accuracy of a Diagnostic Algorithm for the Differential Diagnosis of Vertigo in the ED: the STANDING. Observational Model: Cohort Time Perspective: Prospective Emergency Department Azienda Ospedaliera Universitaria Careggi Firenze, Tuscany, Italy 43
The Treatment of Posterior Semicircular Canal Benign Paroxysmal PositionalVertigo Benign Paroxysmal Positional Vertigo Procedure: Modified Epley maneuver Procedure: Semont maneuver Procedure: Reverse Epley maneuver Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Initial Effectiveness of Treatment for the Posterior Semicircular Canal Benign Paroxysmal Positional Vertigo Delayed Effectiveness of Treatment for the Posterior Semicircular Canal Benign Paroxysmal Positional Vertigo Asan Medical Center Seoul, Songpa-gu, Korea, Republic of 44
Treating Benign Paroxysmal Positional Vertigo (BPPV) in ED Patients Benign Paroxysmal Positional Vertigo Drug: Meclizine Other: Epley Maneuver Drug: Lorazepam (and 2 more...) Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Care Provider) Primary Purpose: Treatment Likert Scale for Satisfaction Lehigh Valley Hospital Allentown, Pennsylvania, United States 45
Is Topiramate Effective in Treating Dizziness in Patient's With Migraine-Associated Dizziness Migraine Headache Dizziness Drug: topiramate Drug: lactulose placebo pill Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment Change in mean 28-day monthly vertigo frequency from baseline. Change in Dizziness Handicap Inventory scores from baseline. Change in an individual's perception of vertigo symptoms based on a 1 to 10 scale. University of California, San Francisco San Francisco, California, United States 46
A Study To Evaluate The Efficacy And Safety Of Betahistine Mesilate In The Treatment Of Patients WithVertigo Caused By Cerebral Infarction In Posterior Circulation Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Changes in the European Evaluation of Vertigo (EEV) scale in 4 weeks. The duration of the vertigo symptom. Beijing Tiantan Hospital Beijing, Beijing, China Beijing Hospital Beijing, Beijing, China Shanghai Renji Hospital Shanghai, Shanghai, China Shanghai Huashan Hospital Shanghai, Shanghai, China 47
Treatments for Benign Paroxysmal PositionalVertigo (BPPV) Behavioral: Canalith repositioning maneuver (Epley maneuver) Behavioral: Semont maneuver Behavioral: Brandt-Daroff exercises (and 2 more...) Allocation: Randomized Masking: Single (Outcomes Assessor) Primary Purpose: Treatment Baylor College of Medicine Houston, Texas, United States 48
Treatment of Posterior Canal Type of Benign Paroxysmal Positional Vertigo Benign Paroxysmal Positional Vertigo (BPPV) Procedure: Canalith repositioning maneuver Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Investigator, Outcomes Assessor) Primary Purpose: Treatment efficacy of repositioning maneuvers for treating PC-BPPV Chonbuk National University Hospital Jeonju, Korea, Republic of 49
Effectiveness of the Epley Manoeuvre Performed in Primary Care to Treat Benign Paroxysmal PositionalVertigo Benign Positional Paroxysmal Vertigo Procedure: PROCEDURE: EPLEY MANOEUVRE Procedure: PROCEDURE: SHAM MANOEUVRE Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Outcomes Assessor) Primary Purpose: Treatment PERSISTENCE OF VERTIGO BETAHISTINE TABLET COUNT NEW EPISODES OF BENIGN PAROXYSMAL POSITIONAL VERTIGO IN THE ANNUAL VISIT (and 3 more...) CAP Florida L'Hospitalet de Llobregat, Barcelona, Spain 50
Cranial Osteopathic Techniques on the Symptoms of Benign Paroxysmal Positional Vertigo Benign Paroxysmal Positional Vertigo Other: The cranial osteopathic techniques Other: Control group Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment Laiana Sepúlveda de Andrade Mesquita Teresina, PiauÃ, Brazil 51
Benign Paroxysmal PositionalVertigo (BPPV) Training for Sports Medicine Providers in a Pediatric Concussion Program Benign Paroxysmal Positional Vertigo Behavioral: Diagnostic training Behavioral: Diagnostic and treatment training Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Other Survey of level of confidence in managing BPPV in concussion patients Time to recovery from concussion Mode of concussion (and 4 more...) 52
Treatment of Geotropic Horizontal Canal Benign Paroxysmal PositionalVertigo Benign Paroxysmal Positional Vertigo Procedure: Gufoni Procedure: Sham Procedure: Barbecue Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Immediate therapeutic effects for the treatment of geotropic HC-BPPV Chonbuk National University Hospital Jeonju, Cholabuk-do, Korea, Republic of Chonnam National University Hospital Kwangju, Cholanam-do, Korea, Republic of Seoul National University Bundang Hospital Seongnam, Kyungki-do, Korea, Republic of 53
Obstructive Sleep Apnea Syndrome (OSAS) andDizziness Sleep Apnea Syndromes, Obstructive Dizziness Eustachian Tube Dysfunction Observational Model: Case-Control Time Perspective: Prospective The change in the score on Dizziness Handicap Inventory (DHI) 54
Head-Mounted Vibrotactile Prosthesis for Patients With Chronic Postural Instability Device: balance prosthesis Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Change in Dynamic Gait Index (DGI) From Baseline to 6 Weeks. Washington University School of Medicine St. Louis, Missouri, United States 55
Proof of Concept Study of EMBalance Decision Support System to Evaluate Balance Disorders Other: Decision Support System (DSS) Other: Specialist Audiovestibular Consultation Other: DSS Customised Vestibular Physiotherapy (and 2 more...) Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Investigator) Primary Purpose: Diagnostic Percentage of diagnosis agreement Percentage of management plan agreement Number of initial diagnoses changed after investigations proposed (and 9 more...) Antwerp University Hospital Edegem, Belgium Freiburg University Medical Center Freiburg, Germany Hippocrateio Hospital Athens, Greece 56
Effects of Physical Treatment on Postural Stability in Benign Paroxysmal PositionalVertigo (BPPV) Patients Benign Paroxysmal Positional Vertigo Other: Epley maneuver Other: Semont maneuver Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Care Provider, Investigator) Primary Purpose: Treatment postural stability subjective vertigo Maccabi health services Beer Sheva, Israel 57
Clinical Aspects of Patients With Benign Paroxysmal Positional Vertigo (BPPV) and Migraine Migraine Positional Vertigo Procedure: Particle re-positioning maneuver Observational Model: Case Control Time Perspective: Cross-Sectional Number of patients who had normal vestibular response to provocative tests 7 days after re-positioning maneuver 58
Stationary Bike Study Vertigo Concussion Dizziness Other: Vestibular Rehabilitation + Aerobic Exercise Other: Vestibular Rehabilitation Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Participant) Primary Purpose: Treatment Changes in Visual Analog Scale (VAS) of Dizziness Score Changes in Dizziness Handicap Inventory (DHI) Score Change in the number of symptoms on checklist of the Sports Concussion Assessment Tool (and 4 more...) New York University School of Medicine New York, New York, United States 59
The Liberatory Maneuver for the Treatment of Benign Paroxysmal PositionalVertigo (BPPV) Vertigo Vestibular Disease Other: Liberatory Maneuver Other: Placebo maneuver Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Outcomes Assessor) Primary Purpose: Treatment Negative Dix-Hallpike maneuver Self reported willingness to move Chicago Dizziness and Hearing Chicago, Illinois, United States Midwestern University Downers Grove, Illinois, United States 60
Effect of V0251 in AcuteVertigo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment "Vertigo Symptoms Score" (VSS) rated by patient using VAS "Concomitant and Vegetative Symptoms Score" (CVSS) rated by patients using VAS Number of patients with Adverse Events as a measure of safety and tolerability Fakultni Nemocnice Hradec Králové Hradec Králové, Czech Republic Regional Hospital Kladno Kladno, Czech Republic Faculty Hospital Ostrava Ostrava, Czech Republic (and 37 more...) 61
Vestibular Evaluation After Vestibular Schwannoma Treatment Radiation: Radiosurgery gammaknife Procedure: Microsurgery resection Observational Model: Case-Control Time Perspective: Retrospective Vestibular evaluation DHI Vestibular evaluation AAO Facial fonction (and 2 more...) CHU Grenoble-Alpes La Tronche, France 62
BPPV Treatment in Biaxial Rotational Chair Benign Paroxysmal Positional Vertigo Device: Biaxial rotational chair Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Participant) Primary Purpose: Treatment Effect of change in velocity in treatment of lateral canal BPPV Haukeland University Hospital Bergen, Norway 63
Efficacy of a Transcranial Vibrating System for Mitigation of Migraine Associated Vertigo Dizziness Nausea Headache Confusion Device: Otoband Device: Otoband sham Allocation: Randomized Intervention Model: Single Group Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Change in vertigo symptoms Brain confusion Change in nausea symptoms Change in headache symptoms Thomas Jefferson Hospital Philadelphia, Pennsylvania, United States 64
Impact of a Magnetic Resonance Imaging (MRI) Scanner Exclusively Dedicated to Emergency in the Clinical Management of Patients Presenting With Diplopia or Dizziness Stroke Dizziness Diplopia (and 2 more...) Observational Model: Case-Control Time Perspective: Prospective Diagnosis is established on the positive signs of stroke highlighted on the CT scan or brain MRI according to the examination performed Evaluate the time of care Number of CT and brain MRI requested by the emergency physician in the before / after groups (and 4 more...) Les Hôpitaux Universitaires de Strasbourg Strasbourg, France 65
Effectiveness of Osteopathic Manipulative Treatment (OMT) and Vestibular Rehabilitation Therapy (VRT) in Individuals With Vertigo Vertigo Dizziness Benign Paroxysmal Positional Vertigo Labyrinthitis Other: Osteopathic Manipulative Treatment (OMT) Other: Vestibular Rehabilitation Therapy (VRT) Allocation: Randomized Intervention Model: Factorial Assignment Masking: Single (Care Provider) Primary Purpose: Treatment Change from Baseline in Dizziness Handicap Inventory (DHI) at 1 week Change from Baseline in Dizziness Handicap Inventory (DHI) at 3 weeks Change from Baseline in Dizziness Handicap Inventory (DHI) at 12 weeks (and 6 more...) Western University Physical Therapy Research Laboratory Pomona, California, United States 66
Vestibular Function Outcome After Cartilage Cap Occlusion Surgery Vestibular Dizziness Superior Semicircular Canal Dehiscence Procedure: cartilage cap occlusion surgery Allocation: Non-Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment objective improvement ABC Scale VAS scores 67
Canalith Repositioning Procedure for BPPV in Primary Care Benign Paroxysmal Positional Vertigo Procedure: Canalith repositioning maneuver (CRM) Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single Primary Purpose: Treatment Self-reported resolution (affirmative response to question: "Do you feel that the dizziness has completely resolved?") of vertigo and/or a negative result of the Dix-Hallpike maneuver Duration of cure, relapse rates McMaster University Hamilton, Ontario, Canada 68
Treatment of Apogeotropic Horizontal Canal Benign Paroxysmal PositionalVertigo Benign Paroxysmal Positional Vertigo Procedure: Gufoni Procedure: Vibration Procedure: Sham Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Outcomes Assessor) Primary Purpose: Treatment Conversion in Direction of Nystagmus From Apogeotropic to Geotropic or Disappearance of Nystagmus Daegu Kyungbook Dizziness society Daegu, Korea, Republic of 69
Different Treatments With the TRV Reposition Chair Benign Paroxysmal Positional Vertigo Procedure: Type of repositional maneuvre Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Evaluation by VNG Measurements Subjective vertigo Dizziness Handicap Inventory (DHI) questionnaire Department of Otolaryngology, Head & Neck Surgery and Audiology Aalborg, North Denmark Region, Denmark 70
Physical Therapy Intervention for Extended Physical Symptoms After a Sports-related Concussion Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Symptomatic Recovery Return to Play Walsh University North Canton, Ohio, United States 71
Rizatriptan for EpisodicDizziness in Vestibular Migraine Vestibular Migraine Migrainous Vertigo Drug: Rizatriptan Drug: Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Proportion of treated vestibular migraine (VM) attacks in which subjects experience a reduction in severity rating Treatment Satisfaction at 48 hours University of California, Los Angeles Los Angeles, California, United States Mayo Clinic Rochester, Minnesota, United States ICAHN School of Medicine at Mount Sinai New York, New York, United States 72
Reducing Rate of Falls in Older People by Means of Vestibular Rehabilitation (ReFOVeRe Study) Device: CDP Device: Mobile posturography Other: 10 sessions Other: 5 sessions Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Investigator, Outcomes Assessor) Primary Purpose: Prevention CDP Average Mobile posturografphy gSBDT Falls (and 3 more...) Complexo Hospitalario Universitario Santiago de Compostela, A Coruña, Spain 73
Interventions for ResidualDizziness After Successful Repositioning Maneuvers in Patients With BPPV Drug: Betahistine Behavioral: Exercise-based vestibular rehabilitation Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Care Provider, Outcomes Assessor) Primary Purpose: Treatment Balance function Duration of RD symptoms Quality of life assessment scale (and 2 more...) Otorhinolaryngology Department of Affiliated Eye and ENT Hospital, Fudan University, Shanghai, China Shanghai, Shanghai, China 74
Effects of Early Vestibular Rehabilitation in Patients WithDizziness and Balance Disorders After Sport Concussion Other: Early Vestibular Rehabilitation Other: Standard of Care Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Investigator) Primary Purpose: Treatment Change in Sports Concussion Assessment Tool (SCATIII) Symptom Inventory Change in Dizziness Handicap Inventory (DHI) Global Rating of Change (GRC) (and 7 more...) University of Michigan Health System Ann Arbor, Michigan, United States 75
Head-Mounted Vibrotactile Prosthesis for Patients With Chronic Postural Instability Vestibular Disorder Dizziness Device: BALCAP prosthesis Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Other Change in DGI Change in CDP Change in Gait Speed (and 2 more...) Washington University School of Medicine Saint Louis, Missouri, United States 76
Vestibular System in Migrainous Vertigo Patients Migraine Disorders Migraine Variant Episodic Recurrent Vertigo Observational Model: Case Control Time Perspective: Prospective Differences in vestibular function Differences in hypersensitivity Dept. of neurology, Sørlandet Hospital HF Kristiansand, Norway 77
Comparison of Efficacy Dimenhydrinate and Metoclopramide in the Treatment of Nausea Due toVertigo Drug: Dimenhydrinate Drug: Metoclopramide Allocation: Randomized Intervention Model: Factorial Assignment Masking: Triple (Participant, Care Provider, Investigator) Primary Purpose: Treatment compare the effects of intravenous dimenhydrinate and metoclopramide in the treatment of nausea due to vertigo in emergency setting. (nausea and vertigo scores as measured by Visual Analogue Scale.) 78
Validation of an iPhone-based Event Recorder for Arrhythmia Detection Arrhythmia, Palpitations, Lightheadedness Device: Alivecor monitor and 14 day event monitor Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Diagnostic Validation of an iPhone-based Event Recorder for Arrhythmia Detection Dent Towers Buffalo, New York, United States 79
BPPV With CRP: Single Versus Multiple Cycles Benign Paroxysmal Positional Vertigo (BPPV) Procedure: Canalith repositioning procedure Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment Dix-Hallpike test (DHT) Dizziness handicap inventory (DHI) Subjective symptoms Loss of balance Department of Otolaryngology Faculty of Medicine, Chiang Mai University 110 Intawaroros Road, Sriphum Chiang Mai, Thailand 80
Efficacy of Vitamin D and Calcium Supplementation on the Prevention of Recurrences in BPPV Benign Paroxysmal Positional Vertigo Drug: 400IU cholecalciferol and 500mg of elemental calcium as calcium carbonate Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Prevention Recurrence frequency of benign paroxysmal positional vertigo Changes in serum 25-hydroxy vitamin D level Falling frequency (and 3 more...) Seoul National Universtiy Bundang Hospital Seongnam-si, Gyeonggi-do, Korea, Republic of 81
Effects of a Vestibular Rehabilitation Maneuver Other: rehabilitation maneuver Allocation: Non-Randomized Intervention Model: Single Group Assignment Masking: Double (Participant, Outcomes Assessor) Primary Purpose: Supportive Care Directional preponderance (DP) Subjective sense of a decrease in imbalance and dizziness. Vestibular and auditory center of Day General Hospital Tehran, Iran, Islamic Republic of 82
Vestibular Rehabilitation for Patients With Fall-related Wrist Fractures Other: Vestibular rehabilitation Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment Vestibular function measured by head shake test Analyze of gait using electronic walkway Lund University, Dep Clin Sci in Malmö/Family Practice Malmö, Sweden 83
Study of Oculomotor Dysfunction Leading to Children Vertigo Vertigo Headache Anomaly of Vergence System (and 2 more...) Procedure: orthoptic rehabilitation Other: Orthoptic diagnostic Allocation: Non-Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Diagnostic oculomotor complete evaluation (static and dynamic and accommodation), posturography test and a visual dynamic acuity test free of symptoms ORL Service - Robert Debre Hospital Paris, France 84
Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients Headache Epilepsy Dizziness Allocation: Non-Randomized Intervention Model: Single Group Assignment Masking: Single Primary Purpose: Diagnostic intensity of vessels, muscle, air signal/noise ratio contrast/nose ratio University of Muenster, Dept. of Clinical Radiology Muenster, Germany 85
Effects of Prismatic Spectacle Lenses on Symptoms ofDizziness , Headache and Anxiety as Caused by Vertical Heterophoria Binocular Dysfunction Vertical Heterophoria Vision, Binocular Vision Disparity Device: Lenses containing prismatic correction Device: Lenses not containing prismatic correction Allocation: Randomized Intervention Model: Crossover Assignment Masking: Double (Participant, Care Provider) Primary Purpose: Treatment Evidence of change / improvement of symptoms of headache, dizziness and anxiety as demonstrated by validated, self-administered survey tools for these symptoms Evidence that a new survey tool developed by the authors to assess changes / improvement in dizziness, headache and anxiety associated with Vertical Heterophoria correlates to validated, self-administered survey tools for these same symptoms Vision Specialists of Birmingham Birmingham, Michigan, United States 86
Telemedical Examination of a Three-Component Oculomotor Testing Battery Device: Telemedical video-oculography system Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Diagnostic Number of evaluable telemedical oculomotor examinations Accuracy of telemedical oculomotor examination (correlation to bedside test) Number of participants with adverse or serious adverse events that are related to telemedical oculomotor examination Time delay of telemedical tests Klinikum München-Harlaching Munich, Bavaria, Germany 87
Game Based Vestibular Exercise for Home Rehabilitation Peripheral Vestibular Disorders Dizziness Behavioral: Experimental group Behavioral: Control group Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment Standing Balance Dizziness Handicap Inventory (DHI) Computerized Visual Tracking Performance Spatial - temporal gait variables during treadmill walking with and without visual tracking task. University of Manitoba Winnipeg, Manitoba, Canada 88
The Head Impulse Test in the Screening of Vestibular Function Other: Video recording of Head Impulse Test Observational Model: Cohort Time Perspective: Prospective Sensitivity of the recorded HIT results in the prediction of the caloric test lateralization parameter Specificity of the VNG recorded HIT results in the prediction of the caloric test lateralization parameter Sensitivity of the bed-side HIT examination results in the prediction of the caloric test lateralization parameter Specificity of the bed-side HIT examination results in the prediction of the caloric test lateralization parameter Otoneurology Unit, Lin Medical Center, 35 Rotchild Avenue Haifa, Israel 89
TRV-chair vs Manual Repositioning Maneuver in Treatment of Benign Paroxysmal PositionalVertigo Device: TRV-chair Procedure: Manual repositioning maneuver Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Number of treatments Treatment success after first treatment Dizziness Handicap Inventory (DHI) questionnaire Adverse events Department of Otolaryngology, Head & Neck Surgery and Audiology Aalborg, North Denmark Region, Denmark 90
Transcranial Vibrating System for Improving Vestibular Physical Therapy Vertigo Dizziness Nausea Balance Device: Transcranial vibrating system Device: Transcranial vibrating system sham Allocation: Randomized Intervention Model: Sequential Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Change in duration of the vestibular physical therapy exercise session Change in dizziness index Change in balance Fyzical - Dizziness and Fall Prevention - Shady Grove Rockville, Maryland, United States FYZICAL Therapy & Balance Center of Rockville Rockville, Maryland, United States 91
Reducing Rate of Falls in Older People by Means of Vestibular Rehabilitation: Preliminary Study Dizziness ChronicFall Elderly Device: Vestibular rehabil.: CDP Device: Vestibular rehabil.: optokinetic stimuli Other: Vestibular rehabil.: home exercises Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Investigator, Outcomes Assessor) Primary Purpose: Prevention CDP average Falls Hospitalisations (and 4 more...) 92
Treatment of Apogeotropic Horizontal Canal Benign Paroxysmal PositionalVertigo Procedure: Gufoni maneuver Procedure: Head-shaking maneuver Procedure: sham maneuver Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Treatment of Apogeotropic Horizontal Canal Benign Paroxysmal Positional Vertigo: A Randomized Clinical Trial Chonbuk National University Hospital Jeonju, Cholabuk-do, Korea, Republic of Seoul National University Bundang Hospital Seongnam, Kyoungki-do, Korea, Republic of 93
Vestibular Rehabilitation and Balance Training After Traumatic Brain Injury Traumatic Brain Injury Brain Concussion Head Injury Dizziness Other: Multidisciplinary evaluation and VR Other: Multidisciplinary evaluation Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment Dizziness Handicap Inventory (DHI) High level mobility assessment tool for traumatic brain injury (HiMAT) Oslo University Hospital Oslo, Norway 94
Evaluation of the Prevalence of BPPV and Longterm Effects of Its Therapy Using the Rotundum Device in Retirement Homes Benign Paroxysmal Positional Vertigo Diagnostic Test: Epley maneuver/Barbeque maneuver Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Screening Prevalence of BPPV Evaluation of predictive Factors 95
Vestibular Consequences of Blast-related Mild Traumatic Brain Injury (TBI) Observational Model: Cohort Time Perspective: Cross-Sectional peripheral vestibular function central vestibular/CNS function postural stability quality of life Mountain Home VA Medical Center James H. Quillen VA Medical Center, Mountain Home, TN Mountain Home, Tennessee, United States 96
Vestibular Function and Vestibular Rehabilitation in SSHL With Vertigo Behavioral: Vestibular rehabilitation Allocation: Randomized Intervention Model: Single Group Assignment Masking: Double (Care Provider, Outcomes Assessor) Primary Purpose: Treatment Assessment of vestibular function status by vestibular function tests in SSHL with vertigo at stage 1(before treatment) Assessment of vestibular function status by vestibular function tests in SSHL with vertigo at stage 2(2 weeks after treatment) Assessment of vestibular function status by vestibular function tests in SSHL with vertigo at stage 2(2 months after treatment) Otorhinolaryngology Department of Affiliated Eye and ENT Hospital, Fudan University, Shanghai, China Shanghai, Shanghai, China 97
The Influence of Vestibular Stimulation on Cardiac Autonomic Control System in Subjects With and Without BPPV Benign Paroxysmal Positional Vertigo Vertigo Autonomic Nervous System Diagnostic Test: Heart rate variability parameters monitoring Observational Model: Case-Control Time Perspective: Prospective Heart Rate Variability- SDNN Heart Rate Variability- RMSSD Dizziness Handicap Inventory Stait- Trait Anxiety Inventory Horowitz Physiotherapy Clinic Tel Aviv, Israel 98
Efficacy of Antiviral Medications in ControllingVertigo Attacks of Patients With Meniere's Disease Drug: Acyclovir Drug: Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Vertigo Hearing Loss Aural Fullness Tinnitus Amiralam Hospital Tehran, Iran, Islamic Republic of 99
Vertigo Perception and Quality of Life in Patients After Surgical Treatment of Vestibular SchwannomaIntervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Supportive Care The GBI questionnaire The GHSI questionnaire The DHI questionnaire 100
Effects of Osteopathic Treatment on Vestibular Disturbed Active Post Concussed Individual Other: Osteopathic treatment Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment Dizziness Handicap Inventory (DHI) Balance Error Scoring System (BESS) Take Flight Athletic Therapy Clinic Carstairs, Alberta, Canada