A new acronym for PPI-REE?

Eosinophilic esophagitis (EoE) is a complex allergic disease commonly associated with food-induced symptomatic esophageal dysfunction.1 This includes reflux, dysphagia, and dysmotility.2 Consensus guidelines have provided clinical information to guide EoE evaluation, including the use of proton pump inhibitors (PPIs), to distinguish gastroesophageal reflux disease from EoE, and observations that a unique subset of eosinophilic esophageal infiltration might be largely resolved using a PPI, also termed PPI-REE (PPI-responsive esophageal eosinophilia).

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