Clinical metric for differentiating intracranial hemangiopericytomas from meningiomas using diffusion weighted MRI

Publication date: Available online 1 November 2018

Source: Clinical Imaging

Author(s): Alexander M. El-Ali, Vikas Agarwal, Andrew Thomas, Ronald L. Hamilton, Christopher G. Filippi

Abstract

Purpose

Intracranial Hemangiopericytomas (IHP) are dural based tumors that frequently recur/metastasize. Unfortunately, their imaging appearance overlaps significantly with more benign meningiomas. We evaluated the use of diffusion weighted imaging (DWI) to differentiate IHP from meningioma.

Methods

We compared MRI of IHP tumors (WHO Grades II/III) (n = 20) to meningioma (n = 48, WHO Grade I/II).

Findings

ADC values differed between IHP (1.05 × 10–3 mm2/s) and meningiomas (0.89 × 10–3 mm2/s) (p = 0.05). Normalized ADC ratios (nADC), differed between IHP and meningiomas (1.30 vs 1.07, p = 0.03).

Conclusion

Importantly, a nADC cutoff of >1.3 was specific (96%) but not sensitive (35%) for identifying IHP.

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