Publication date: Available online 31 October 2018
Source: Clinical Imaging
Author(s): Sung Shick Jou, Kunihiro Yagihashi, Jordan Alexander Zach, David Lynch, Young Ju Suh, COPDGene Investigators
Abstract
Purpose
To evaluate whether visual CT findings could account for the effect of current smoking.
Methods
500 CT scans were visually evaluated within each lobe. A multivariate model for emphysema index was constructed containing previously described confounders in addition to the visual components associated with smoking status.
Results
Current smokers displayed 23% less visual emphysema, 19% more airway wall thickening, and 188% more centrilogular nodule than former smokers (all p < 0.001). The effect of current smoking on the emphysema index decreased after adjustment with confounders and visual parameters.
Conclusions
Visual CT findings could partially account for the effect of current smoking.
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