Circulating Histones Are Major Mediators of Multiple Organ Dysfunction Syndrome in Acute Critical IllnessesObjectives: Multiple organ dysfunction syndrome is characterized by simultaneous multiple organ failure, which is the leading cause of death in acute critically ill patients. However, what mediates multiple organ dysfunction syndrome is not fully understood. The discovery of toxic effects by extracellular histones on different individual organs strongly suggests their involvement in multiple...
Impact of Telemonitoring of Critically Ill Emergency Department Patients Awaiting Intensive Care Unit TransferObjectives: Because of overcrowding and limited critical care resources, critically ill patients in the emergency department may spend hours to days awaiting transfer to the ICU. In these patients, often termed "ICU boarders," delayed ICU transfer is associated with poor outcomes. We implemented an emergency department–based, electronic ICU monitoring system for ICU boarders. Our aim was...
Fluid Overload Associates With Major Adverse Kidney Events in Critically Ill Patients With Acute Kidney Injury Requiring Continuous Renal Replacement TherapyObjectives: We examined the association between fluid overload and major adverse kidney events in critically ill patients requiring continuous renal replacement therapy for acute kidney injury. Design: Retrospective cohort study. Setting: ICU in a tertiary medical center. Patients: Four-hundred eighty-one critically ill adults requiring continuous...
Intracranial Hypertension and Cerebral Perfusion Pressure Insults in Adult Hypertensive Intraventricular Hemorrhage: Occurrence and Associations With OutcomeObjectives: Elevated intracranial pressure and inadequate cerebral perfusion pressure may contribute to poor outcomes in hypertensive intraventricular hemorrhage. We characterized the occurrence of elevated intracranial pressure and low cerebral perfusion pressure in obstructive intraventricular hemorrhage requiring extraventricular drainage....
Outcome Prediction in Postanoxic Coma With Deep LearningObjectives: Visual assessment of the electroencephalogram by experienced clinical neurophysiologists allows reliable outcome prediction of approximately half of all comatose patients after cardiac arrest. Deep neural networks hold promise to achieve similar or even better performance, being more objective and consistent. Design: Prospective cohort study. Setting: Medical ICU of five teaching hospitals in the Netherlands. Patients: Eight-hundred...
Outcome Prediction in Postanoxic Coma With Deep LearningObjectives: Visual assessment of the electroencephalogram by experienced clinical neurophysiologists allows reliable outcome prediction of approximately half of all comatose patients after cardiac arrest. Deep neural networks hold promise to achieve similar or even better performance, being more objective and consistent. Design: Prospective cohort study. Setting: Medical ICU of five teaching hospitals in the Netherlands. Patients: Eight-hundred...
Outcome Prediction in Postanoxic Coma With Deep LearningObjectives: Visual assessment of the electroencephalogram by experienced clinical neurophysiologists allows reliable outcome prediction of approximately half of all comatose patients after cardiac arrest. Deep neural networks hold promise to achieve similar or even better performance, being more objective and consistent. Design: Prospective cohort study. Setting: Medical ICU of five teaching hospitals in the Netherlands. Patients: Eight-hundred...
Sphenoid sinus pneumatization, septation, and the internal carotid artery: A computed tomography studyOlusola C Famurewa, Bolanle O Ibitoye, Sanyaolu A Ameye, Christianah M Asaleye, Oluwagbemiga O Ayoola, Olaoluwa S OnigbindeNigerian Medical Journal 2018 59(1):7-13Background: The air spaces of the nasal cavity and the sphenoid sinus (SS) constitute a convenient corridor to access lesions of the skull base using the endoscopic endonasal transsphenoidal approach (EETA). Safe EETA depends on the SS...
Postpartum sequelae of the hypertensive diseases of pregnancy: A pilot studyOchuwa Adiketu Babah, Olalekan Olaleye, Bosede B AfolabiNigerian Medical Journal 2018 59(1):1-6Background: Hypertensive disorders are one of the most common medical conditions that may complicate pregnancy. Postpartum blood pressure (BP) pattern is, however, less clear in affected women and decision to discharge them is usually decided arbitrarily. Materials and Methods: A cohort study conducted at Lagos University Teaching...
Contrast-Associated Acute Kidney InjuryRoxana Mehran, M.D., George D. Dangas, M.D., Ph.D., and Steven D. Weisbord, M.D.ArticleFigures/MediaMetrics72 ReferencesFigure 1.Classification of Available Contrast Agents.Contrast-associated acute kidney injury is characterized by a decrease in kidney function that occurs within days after the intravascular administration of iodinated contrast material. In the 1950s, initial cases were reported in patients with preexisting kidney disease who were undergoing...
Muco-Obstructive Lung DiseasesRichard C. Boucher, M.D.ArticleFigures/MediaMetrics75 ReferencesA spectrum of lung diseases that affect the airways, including chronic obstructive pulmonary disease (COPD), cystic fibrosis, primary ciliary dyskinesia, and non–cystic fibrosis bronchiectasis, can be characterized as muco-obstructive diseases.1-4 These diseases have the clinical features of cough, sputum production, and episodic exacerbations that are often associated with a diagnosis of chronic bronchitis.5...
Controlled Trial of Budesonide–Formoterol as Needed for Mild AsthmaRichard Beasley, D.Sc., Mark Holliday, B.Sc., Helen K. Reddel, Ph.D., Irene Braithwaite, Ph.D., Stefan Ebmeier, B.M., B.Ch., Robert J. Hancox, M.D., Tim Harrison, M.D., Claire Houghton, B.M., B.S., Karen Oldfield, M.B., Ch.B., Alberto Papi, M.D., Ian D. Pavord, F.Med.Sci., Mathew Williams, Dip.Ex.Sci., et al., for the Novel START Study Team*AbstractBACKGROUNDIn double-blind, placebo-controlled trials, budesonide–formoterol used on...
Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of StrokeHenry Ma, Ph.D., Bruce C.V. Campbell, Ph.D., Mark W. Parsons, Ph.D., Leonid Churilov, Ph.D., Christopher R. Levi, M.B., B.S., Chung Hsu, Ph.D., Timothy J. Kleinig, Ph.D., Tissa Wijeratne, M.D., Sami Curtze, Ph.D., Helen M. Dewey, Ph.D., Ferdinand Miteff, M.B., B.S., Chon-Haw Tsai, Ph.D., et al., for the EXTEND Investigators*AbstractBACKGROUNDThe time to initiate intravenous thrombolysis for acute ischemic stroke is generally...
How to Perform an Elliptical Excision of the SkinTomas J. Saun, M.D., Jessica Truong, M.D., Shelly P. Dev, M.D., and Kyle Wanzel, M.D.https://www.nejm.org/doi/full/10.1056/NEJMvcm1404883?query=primarycare-hospitalistThis video demonstrates elliptical excision of the skin, a procedure that can be used in the diagnosis and management of skin and subcutaneous lesions, may be performed with minimal risk in most patients, and may avert the need for other, more invasive procedures.Watch this video and...
Coronary Arteritis in IgG4-Related DiseaseJaime de la Fuente, M.D., and Jared Bird, M.D.A 47-year-old man presented to the cardiology clinic for evaluation of coronary-artery dilatations that had been detected on computed tomography (CT) of the chest performed as a follow-up examination of pulmonary nodules. The patient was asymptomatic but had a history of biopsy-proven IgG4-related disease involving the pancreas and the lacrimal and parotid glands. At the current presentation, he had no swelling...
Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil LevelStephen C. Lazarus, M.D., Jerry A. Krishnan, M.D., Ph.D., Tonya S. King, Ph.D., Jason E. Lang, M.D., Kathryn V. Blake, Pharm.D., Ronina Covar, M.D., Njira Lugogo, M.D., Sally Wenzel, M.D., Vernon M. Chinchilli, Ph.D., David T. Mauger, Ph.D., Anne-Marie Dyer, M.S., Homer A. Boushey, M.D., et al., for the National Heart, Lung, and Blood Institute AsthmaNet*AbstractBACKGROUNDIn many patients with mild, persistent asthma, the percentage...
Early detection of diabetic polyneuropathy using paired stimulation studies of the sensory nervesObjective This study seeks to use the RRP, a sensitive parameter for detecting early change in peripheral polyneuropathies, as a tool for early detection of diabetic polyneuropathy (DPN). Design The RRP of the median and sural sensory nerves were measured in 57 diabetic patients (male 31, female 26) and 23 healthy controls (male 16, female 7). The shortest inter-stimulus interval, where the latency of...
The Validity of the Montreal Cognitive Assessment for Moderate to Severe Traumatic Brain Injury Patients: A Pilot StudyObjective To pilot the use of Montreal Cognitive Assessment (MOCA) as a quick clinical screen for cognitive assessment in traumatic brain injury (TBI) patients. Design The study recruited 61 participants with moderate to severe TBI presenting to a tertiary rehabilitation center under the Brain Injury Program. A MOCA questionnaire and neuropsychological battery (Repeatable Battery...
Differences in the mitochondrial and lipid droplet morphology in female office workers with trapezius myalgia, compared to healthy controls. A muscle biopsy studyObjective Trapezius myalgia, or more specific, myofascial dysfunction of the upper trapezius mainly affects women performing jobs requiring prolonged low level activation of the muscle. This continuous low muscle load can be accompanied by a shift to a more anaerobic energy metabolism, causing pain. To investigate whether morphological signs...
EMG Evaluation of Bodyweight Exercise Progression in a Validated ACL Injury Rehabilitation Program: Cross-sectional StudyObjectives Regaining muscle strength is essential for successful outcome after anterior cruciate ligament (ACL) injury, why progression of exercise intensity in ACL injury rehabilitation is important. Thus, this study evaluated hamstring and quadriceps muscle activity progression during bodyweight exercises used in a validated ACL injury rehabilitation program. Design The study...
A NEW THRESHOLD FOR APPENDICULAR LEAN MASS DISCRIMINATES MUSCLE WEAKNESS IN WOMEN WITH HIP FRACTURE: A CROSS-SECTIONAL STUDY.Objective To investigate the relationship between measures of muscle mass and grip strength in women with subacute hip fracture. Firstly, we aimed to assess the capability of the current thresholds for appendicular lean mass (aLM), aLM-to-body-mass-index ratio and aLM/height2 to separate weak and non-weak women. Secondly, we aimed to explore alternative thresholds for the 3...
Use of Platelet Rich Plasma for the Treatment of Acetabular Labral Tear of the Hip: A Pilot StudyObjective This study aims to assess whether ultrasound guided injection of platelet rich plasma (PRP) can safely and effectively treat symptoms associated with acetabular hip labral tears. Design Institutional Review Board (IRB) approval was gained for a prospective study of eight patients (N=8), who have previously failed conservative management, to receive ultrasound-guided injection of PRP at the site...
Painful Foot Disorders in the Geriatric Population: A Narrative ReviewPainful foot disorders are highly prevalent among older adults causing a significant impact on mobility, function, and risk of falls. Despite its significance, foot pain is often interpreted as a normal part of aging and relatively ignored by health care providers as well as by the elderly themselves. Accurate diagnosis of the cause of foot pain is possible for most cases via clinical evaluation without a costly workup. Clinicians...
Dalspinin isolated from Spermacoce hispida (Linn.) protects H9c2 cardiomyocytes from hypoxic injury by modulating oxidative stress and apoptosisPublication date: 15 September 2019Source: Journal of Ethnopharmacology, Volume 241Author(s): R. Lakshmi Sundaram, Hannah R. VasanthiAbstractEthnopharmacological relevanceSpermacoce hispida (S.hispida), a potential medicinal plant has been traditionally used as an antibacterial, antieczemic, antihypertensive, antidiabetic and antihyperlipidemic agent. Although,...
Alkaloids of dendrobium nobile lindl. Altered hepatic lipid homeostasis via regulation of bile acidsPublication date: 15 September 2019Source: Journal of Ethnopharmacology, Volume 241Author(s): Si Huang, Qing Wu, Hao Liu, Hua Ling, Yuqi He, Changhong Wang, Zhengtao Wang, Yanliu Lu, Yuanfu LuAbstractEthnopharmacological relevanceAccumulation of hepatic lipid promotes systemic metabolic dysfunction and results in fatty liver. Our previous studies have shown that the alkaloids of Dendrobium nobile Lindl....
Bioactivities of serotonin transporter mediate antidepressant effects of Acorus tatarinowii SchottPublication date: 15 September 2019Source: Journal of Ethnopharmacology, Volume 241Author(s): Feng-Hong Zhang, Zhi-Mei Wang, Yan-Ting Liu, Ji-Sheng Huang, Shuang Liang, Hong-Hua Wu, Yan-Tong XuAbstractEthnopharmacological relevanceAcrorus tatarinowii Schott has been widely used in the treatments of neuropsychiatric and digestive disorders in clinical practices of traditional Chinese medicine for thousands...
Mass spectrometry-based urinary metabolomics for the investigation on the mechanism of action of Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. leaves against ischemic stroke in ratsPublication date: 15 September 2019Source: Journal of Ethnopharmacology, Volume 241Author(s): Rongjin Wang, Liqiang Shi, Shu Liu, Zhiqiang Liu, Fengrui Song, Zhiheng Sun, Zhongying LiuAbstractEthnopharmacological relevanceAs a traditional Chinese medicine, Eleutherococcus senticosus (Rupr. & Maxim.) Maxim....
Carica papaya seed extract slows human spermPublication date: 15 September 2019Source: Journal of Ethnopharmacology, Volume 241Author(s): V. Ghaffarilaleh, D. Fisher, R. HenkelAbstractEthnopharmacological relevanceTraditional healers use Carica papaya seeds as a remedy for diseases and as a contraceptive for men and abortion in women.Material and methodsSemen samples from 35 healthy men were allowed to liquefy and subsequently incubated for 60 min in Human Tubular Fluid medium containing 1% bovine...
A community-based cross-sectional study about knowledge, attitude, and practices of food safety measures among urban householdsShilpa Reddy Ganta, Deepti M KadeangadiIndian Journal of Health Sciences and Biomedical Research (KLEU) 2019 12(2):154-159OBJECTIVE: The objective of this study was to assess knowledge, attitude, and practices of food safety measures among urban households of Belagavi using the World Health Organization (WHO) "Five keys for food safety." MATERIALS AND METHODOLOGY: A community-based...
Prevalence of Vitamin D deficiency in patients with acute exacerbations of bronchial asthma: A one-year hospital-based cross-sectional studySrinija Kummaraganti, Gajanan S GaudeIndian Journal of Health Sciences and Biomedical Research (KLEU) 2019 12(2):132-138BACKGROUND AND OBJECTIVES: Bronchial asthma is one of the most common chronic diseases. In India, bronchial asthma has 66% frequency of reported exacerbations. Vitamin D has action on pro-inflammatory mediators and smooth muscle function and...
Quantification of mast cells in reactive oral lesions – A clue to the morphologic diversitySaurabh Shekar, Punnya V AngadiIndian Journal of Health Sciences and Biomedical Research (KLEU) 2019 12(2):123-126OBJECTIVE: Inflammatory fibrous hyperplasia (IFH), pyogenic granuloma (PG), peripheral ossifying fibroma (POF), and peripheral giant cell granuloma (PGCG) are common oral soft-tissue reactive lesions that correspond to excessive connective tissue proliferation as a reaction to trauma or irritational...
Impact of refractive error correction on mental and visual development in children with global developmental delayKS Smitha, VD Patil, Mahesh D Kamate, Madhav Prabhu, Umesh Harakuni, OP RakshithaIndian Journal of Health Sciences and Biomedical Research (KLEU) 2019 12(2):117-122PURPOSE: The purpose of the present study is to evaluate visual acuity and refractive status in children with global developmental delay (GDD) and to study the effect of early correction of refractive errors on vision and developmental...
Cytotoxic activity of endophytes isolated from Allamanda blanchetii A. DCHarsha D Pednekar, Harsha V Hegde, Pramod J Hurakadale, Jyoti D Wagawade, Kishore G Bhat, Chetana BogarIndian Journal of Health Sciences and Biomedical Research (KLEU) 2019 12(2):112-116AIM: To evaluate the cytotoxic potential of endophytic fungi isolated from A. blanchetii. MATERIALS AND METHODS: Endophytic fungi were isolated from A. blanchetii using surface sterilization methods, grown in different types of media to ascertain...
Evaluation of interface reflectivity and corneal aberrations following Descemet's stripping automated endothelial keratoplastyHamid Khakshour, Malihe Nikandish, Maryam Salehi, Haleh Ghooshkhanehei, Amirhosein VejdaniOman Journal of Ophthalmology 2019 12(2):108-113PURPOSE: This study aims to evaluate visual outcome after Descemet's membrane stripping automated endothelial keratoplasty (DSAEK) and relate to interface and corneal higher-order aberrations (HOAs). MATERIALS AND METHODS: We enrolled 16...
Outcomes of lacrimal gland injection of botulinum toxin in functional versus nonfunctional epiphoraSwati Singh, Akshay Gopinathan Nair, Md Shahid Alam, Bipasha MukherjeeOman Journal of Ophthalmology 2019 12(2):104-107PURPOSE: The purpose of this study is to assess the outcomes of lacrimal gland injections of botulinum toxin A (BoNTA) for epiphora secondary to lacrimal drainage disorders and functional epiphora. METHODS: This was a retrospective interventional case series where cases were divided...
Twenty-four-month real-world visual outcomes of intravitreal aflibercept as monotherapy for the treatment of neovascular age-related macular degenerationThomas Siempis, Mariam El Abiary, Radhika Patel, Manish GuptaOman Journal of Ophthalmology 2019 12(2):99-103BACKGROUND: Aflibercept is widely used as a treatment for neovascular age-related macular degeneration (nAMD). Nevertheless, there is no consensus in the optimal injection frequency in the 2nd year of treatment along with little real-world...
Risk factors for endothelial cell damage in diabetics after phacoemulsificationNiruban Ganesan, Renuka Srinivasan, K Ramesh Babu, Muthukrishnan VallinayagamOman Journal of Ophthalmology 2019 12(2):94-98Background: To assess the corneal endothelium, central corneal thickness and the factors associated with endothelial cell damage after phacoemulsification in diabetics in comparison with non-diabetics Methods: It was a case control study with 80 eyes each in the diabetic group and the control group....
The feasibility and efficacy of intraoperative laser retinopexy in scleral buckling surgeryRoshija Khanal Rijal, Deepesh MouryaOman Journal of Ophthalmology 2019 12(2):84-87BACKGROUND: This study was performed to assess the feasibility and efficacy of intraoperative laser retinopexy in scleral buckling (SB) surgery. MATERIALS AND METHODS: This was a retrospective, noncomparative, and interventional study. Records of 25 patients who had undergone intraoperative laser retinopexy during SB were retrospectively...
Vitrectomy versus Phaco-vitrectomyAhmed Sulaiman Al-HinaiOman Journal of Ophthalmology 2019 12(2):71-72Android mobile applications in eye careSiddharth Karuppasamy Karthikeyan, Rajesh Thangarajan, Nagarajan Theruvedhi, Krithica SrinivasanOman Journal of Ophthalmology 2019 12(2):73-77Google Play Store was used to search for eye care-related applications the android simulator using various general terms related to eye care to review and categorize various interactive eye care-related applications in...
Painful Foot Disorders in the Geriatric Population: A Narrative ReviewPainful foot disorders are highly prevalent among older adults causing a significant impact on mobility, function, and risk of falls. Despite its significance, foot pain is often interpreted as a normal part of aging and relatively ignored by health care providers as well as by the elderly themselves. Accurate diagnosis of the cause of foot pain is possible for most cases via clinical evaluation without a costly workup. Clinicians...
Protective effect of Shaoyao Decoction against colorectal cancer via the Keap1–Nrf2–ARE signaling pathwayPublication date: 15 September 2019Source: Journal of Ethnopharmacology, Volume 241Author(s): Xiaoyan Wang, Shakir M. Saud, Xiwen Zhang, Weidong Li, Baojin HuaAbstractEthnopharmacological relevanceUlcerative colitis is one of the three high risk factors for colorectal cancer. Studies have found that about 20% of cancers are caused by repeated chronic inflammatory stimuli over a long period of...
Pediatric renal transplantsRB Nerli, Shridhar C GhaganeIndian Journal of Health Sciences and Biomedical Research (KLEU) 2019 12(2):99-100Burnout among healthcare professionals: Is it a cause for concern?Punnya V AngadiIndian Journal of Health Sciences and Biomedical Research (KLEU) 2019 12(2):101-102Maternal mental health and its influence on infant growth and development: A systematic review of observational studies in South and East AsiaShubhashree Venkatesh, J Vindhya, Anita NathIndian Journal...
Therapeutic potential of intravesical injections of platelet-rich plasma in the treatment of lower urinary tract disorders due to regenerative deficiencyQian-Sheng Ke, Jia-Fong Jhang, Teng-Yi Lin, Han-Chen Ho, Yuan-Hong Jiang, Yuan-Hsiang Hsu, Hann-Chorng KuoTzu Chi Medical Journal 2019 31(3):135-143The bladder urothelium plays an important role of barrier function to prevent influx of urinary toxic substance and bacteria. When there is insult to the urinary bladder, the urothelium will start to...
Ischemic stroke following neck dissection in the elderlyChuan-Yi Kuo, Yi-Ting Chen, Cheuk-Kwan Sun, Kuo-Chuan HungTzu Chi Medical Journal 2019 31(3):177-181Objective: Despite the known association of perioperative stroke with perioperative mortality, the prevalence of stroke following neck dissection in elderly patients remains unclear. This study compared the incidence of neck dissection-associated perioperative stroke in elderly and younger patients. Materials and Methods: Totally, 1057 patients...
tea and coffee in the development of gastroesophageal reflux diseaseTao-Yang Wei, Pang-Hsin Hsueh, Shu-Hui Wen, Chien-Lin Chen, Chia-Chi WangTzu Chi Medical Journal 2019 31(3):169-176Objective: The incidence of gastroesophageal reflux disease (GERD) is increasing, and the disease has a close association with dietary habits. This study aims to investigate the role of tea and coffee drinking in the development of GERD. Materials and Methods: This study prospectively enrolled individuals who underwent...
Optimal imaging time for Tc-99m phytate lymphoscintigraphy for sentinel lymph node mapping in patients with breast cancerChing-Chun Ho, Yu-Hung Chen, Shu-Hsin Liu, Hwa-Tsung Chen, Ming-Che LeeTzu Chi Medical Journal 2019 31(3):163-168Objectives: Sentinel lymph node (SLN) sampling has become a standard practice in managing early-stage breast cancer. Lymphoscintigraphy is one of the major methods used. The radioactive tracer used in Taiwan is Tc-99m phytate. However, this agent is not commonly used...
Comparison of intramuscular methylergometrine, rectal misoprostol, and low-dose intravenous oxytocin in active management of the third stage of laborRuchi Jain, Sudesh Agrawal, Kamala Verma, Aastha Jain, Mayank BaidTzu Chi Medical Journal 2019 31(3):158-162Objective: Active management of the third stage of labor (AMTSL) is a critical intervention for the prevention of postpartum hemorrhage (PPH), which is still the most common cause of maternal morbidity and mortality worldwide. The objective of...
Therapeutic potential of intravesical injections of platelet-rich plasma in the treatment of lower urinary tract disorders due to regenerative deficiencyQian-Sheng Ke, Jia-Fong Jhang, Teng-Yi Lin, Han-Chen Ho, Yuan-Hong Jiang, Yuan-Hsiang Hsu, Hann-Chorng KuoTzu Chi Medical Journal 2019 31(3):135-143The bladder urothelium plays an important role of barrier function to prevent influx of urinary toxic substance and bacteria. When there is insult to the urinary bladder, the urothelium will start to...
Anticoagulants for cancer-associated ischemic strokeJin-Yi Hsu, An-Bang LiuTzu Chi Medical Journal 2019 31(3):144-148Patients with cancer-associated ischemic stroke pose similar clinical manifestations and image characteristics, mainly embolic infarction, as patients with atrial fibrillation do. D-dimer, a degraded product of fibrin polymer, is a useful indicator of hypercoagulability, which frequently increases in cancer-associated stroke, but not in stroke resulted from atrial fibrillation. The...
Robotic-assisted minimally invasive oesophagectomy for cancer: An initial experienceChinnusamy Palanivelu, Sumanta Dey, Sandeep Sabnis, Raghavendra Gupta, Bharath Cumar, Saravana Kumar, Ramesh Natarajan, Parthasarathi RamakrishnanJournal of Minimal Access Surgery 2019 15(3):234-241Background: The morbidity related to radical oesophagectomy can be reduced by adopting minimally invasive techniques. Over 250 thoraco-laparoscopic oesophagectomy (TLE) was done in our centre over the last 15 years, before...
The unwanted third wheel in the Calot's triangle: Incidence and surgical significance of caterpillar hump of right hepatic artery with a systematic review of the literatureLuigi Marano, Alberto Bartoli, Karol Polom, Raffaele Bellochi, Alessandro Spaziani, Giampaolo CastagnoliJournal of Minimal Access Surgery 2019 15(3):185-191Background: Caterpillar hump of the right hepatic artery is a rare variation increasing the risk of vascular and biliary injuries during hepatobiliary surgery. The aim of this...
A prospective study of gastro-oesophageal reflux disease symptoms and quality of life 1-year post-laparoscopic sleeve gastrectomyAndrew G.N. Robertson, Andrew J Cameron, Brian Joyce, Phil Le Page, Bruce Tulloh, Andrew C de Beaux, Peter J LambJournal of Minimal Access Surgery 2019 15(3):229-233Introduction: There are concerns that laparoscopic sleeve gastrectomy (LSG) can cause severe gastro-oesophageal reflux disease (GORD). The aim of this study was to assess GORD symptoms and quality of life following...
Priapism in a pediatric chronic myeloid leukaemia patient: Unusual presentation of a rare disease...
Priapism in a pediatric chronic myeloid leukaemia patient: Unusual presentation of a rare disease in childrenPurnima Thakur, Vishal Verma, Vikas Fotedar, Kalindi SinghClinical Cancer Investigation Journal 2019 8(2):76-78A rare case of chronic myeloid leukemia (CML) presenting with priapism is reported in a pediatric patient. CML accounts for around 15% of hematological malignancies. It is still rarer in the pediatric age group. Investigations revealed hyperleukocytosis due to CML. When conservative...
Superficial extraskeletal ewing's sarcoma of forefoot with inguinal lymph node metastasis and lung metastasis: A rare casePoorva Vias, Shabnum Thakur, Rajeev K Seam, Vikas Fotedar, Ashish SaklaniClinical Cancer Investigation Journal 2019 8(2):73-75Ewing's sarcoma is the 2nd most common paediatric bone tumour but can also be seen in extraskeletal sites. Superficial extraskeletal ES is a rare entity and is rarely seen in foot. Majority of these patients are females in second decade of life, presenting...
Metaplastic chondroid breast carcinoma: A diagnostic challengeMilind Anil BhatkuleClinical Cancer Investigation Journal 2019 8(2):70-72Metaplastic carcinoma of the breast is a rare entity. Extensive chondroid differentiation is even rarer in metaplastic breast carcinoma (MBC). Here, we report a case of metaplastic chondroid carcinoma of the breast with very few areas showing usual ductal carcinoma and pseudosarcomatous areas. The tumor was characterized by an abundant chondromyxoid matrix. The definitive...
A study of clinicopathologic features of thyroid cancer in Western Iran: A 9-year experienceBabak Izadi, Somayeh Jalilian, Mazaher Ramezani, Masoud Sadeghi, Sedigheh KhazaeiClinical Cancer Investigation Journal 2019 8(2):64-69Introduction: Thyroid cancer is reported as the most rapidly increasing and third-most common cancer among females. This study aimed to evaluate the data related to thyroid cancer in Kermanshah, Iran, for the first time. Materials and Methods: The data of thyroid cancers were...
An evaluation of special AT-rich sequence-binding protein 2 expression in primary epithelial tumors and metastatic tumors of the ovaryEsra Oz, Zehra Bozdag, Neslihan Bayramoglu Tepe, Zeynep Bayramoglu, Omer Faruk Dizibuyuk, Metin KarakokClinical Cancer Investigation Journal 2019 8(2):57-63Background: Ovarian cancer is the second most common gynecologic cancer in women. Differential diagnosis between primary and metastatic neoplasms can be problematic in some cases. The special AT-rich sequence-binding...
Response assessment of gefitinib therapy in the epidermal growth factor receptor- mutant advanced adenocarcinoma lung at a tertiary care center in North IndiaAnubhuti Singh, Anand Srivastava, Abhishek Verma, Rajiv GargClinical Cancer Investigation Journal 2019 8(2):41-46Context: Oral tyrosine kinase inhibitors (TKIs) have been proven to improve response rates (RRs) and progression-free survival in a chemo-naïve setting in the epidermal growth factor receptor (EGFR)-mutant advanced lung adenocarcinoma...
Response assessment of gefitinib therapy in the epidermal growth factor receptor- mutant advanced adenocarcinoma lung at a tertiary care center in North IndiaAnubhuti Singh, Anand Srivastava, Abhishek Verma, Rajiv GargClinical Cancer Investigation Journal 2019 8(2):41-46Context: Oral tyrosine kinase inhibitors (TKIs) have been proven to improve response rates (RRs) and progression-free survival in a chemo-naïve setting in the epidermal growth factor receptor (EGFR)-mutant advanced lung adenocarcinoma...
Surgical margins and nodal metastasis are prognostic factors in oral squamous cell carcinoma: A meta-analysisMohammad Akheel, Rinku K George, Amit Jain, Qutubuddin Chahwala, Ashmi WadhwaniaClinical Cancer Investigation Journal 2019 8(2):47-51Background: To find out whether surgical margins and nodal metastasis are prognostic factors in oral squamous cell carcinoma (OSCC). Materials and Methods: PubMed search was done to look for studies done on surgical margins and nodal metastasis of OSCC from 2008...
Alexandros Sfakianakis
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182
6948891480
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