Abstract Low-dose ionizing radiation (IR) responses remain an unresolved issue in radiation biology and risk assessment. Accurate knowledge of low-dose responses is important for estimation of normal tissue risk in cancer radiotherapy or health risks from occupational or hazard exposure. Cellular responses to low-dose IR appear diverse and stochastic in nature and to date no model has been proposed to explain the underlying mechanisms. Here, we propose a hypothesis on IR-induced...
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Related Articles The clinical training centers fellowships: a European School of Oncology career development program (2013-2019). Future Oncol. 2020 Jun 21;: Authors: Pavlidis N, Peccatori FA, Aapro M, Eniu A, Cavalli F, Costa A Abstract Aim: This article refers to the European School of Oncology Clinical Training Centers (CTCs) program, which is a granted Fellowships program dedicated to young oncologists in training. Materials & methods:...
Tue Jun 23, 2020 16:14
Related Articles What is the alternative? Responding strategically to cancer misinformation. Future Oncol. 2020 Jun 21;: Authors: Peterson JS, Swire-Thompson B, Johnson SB PMID: 32564627 [PubMed - as supplied by publisher]
Tue Jun 23, 2020 16:14
Related Articles B-cell epitope peptide cancer vaccines: a new paradigm for combination immunotherapies with novel checkpoint peptide vaccine. Future Oncol. 2020 Jun 21;: Authors: Kaumaya PT Abstract In light of the numerous US FDA-approved humanized monoclonal antibodies (mAbs) for cancer immunotherapy, it is surprising that the advancement of B-cell epitope vaccines designed to elicit a natural humoral polyclonal antibody response has not...
Tue Jun 23, 2020 16:14
Related Articles A clinical dilemma amid COVID-19 pandemic: missed or encountered diagnosis of cancer? Future Oncol. 2020 Jun 21;: Authors: Yekedüz E, Karcıoğlu AM, Utkan G, Ürün Y PMID: 32564611 [PubMed - as supplied by publisher]
Tue Jun 23, 2020 16:14
Publication date: August 2020Source: Cancer Epidemiology, Volume 67Author(s): Suleeporn Sangrajrang, Mathieu Laversanne, Rangsiya Bausom, Les Mery, Freddie Bray
Tue Jun 23, 2020 16:11
Publication date: August 2020Source: Cancer Epidemiology, Volume 67Author(s): Carlotta Palumbo, Angela Pecoraro, Giuseppe Rosiello, Stefano Luzzago, Marina Deuker, Franziska Stolzenbach, Zhe Tian, Shahrokh F. Shariat, Claudio Simeone, Alberto Briganti, Fred Saad, Alfredo Berruti, Alessandro Antonelli, Pierre I. Karakiewicz
Tue Jun 23, 2020 16:11
Publication date: Available online 23 June 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): K.E.M. French, M. Gormley, A. Kana, S. Deacon, P.J. Revington
Tue Jun 23, 2020 16:11
Publication date: Available online 23 June 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): Y.-S. Chae, J.-Y. Lee, J.-W. Lee, J.-Y. Park, S.M. Kim, J.-H. Lee
Tue Jun 23, 2020 16:11
Abstract Purpose This study examined the association between smoking and perioperative complications of laparoscopic abdominal surgery and whether these complications were reduced with ≥ 4 weeks of preoperative smoking cessation. Methods A total of 555 patients who underwent gastric and colorectal cancer surgeries under general anesthesia were divided...
Tue Jun 23, 2020 03:00
Related Articles The preclinical discovery and development of agomelatine for the treatment of depression. Expert Opin Drug Discov. 2020 Jun 22;:1-12 Authors: Konstantakopoulos G, Dimitrakopoulos S, Michalopoulou PG Abstract INTRODUCTION: Under the treatment of commonly used antidepressants, many patients with major depressive disorder (MDD) do not achieve remission. All previous first-line treatments for depression have focused on the enhancement...
Tue Jun 23, 2020 15:58
Related Articles What ketamine can teach us about the opioid system in depression? Expert Opin Drug Discov. 2020 Jun 22;:1-4 Authors: Perez-Caballero L, Perez V, Berrocoso E PMID: 32568562 [PubMed - as supplied by publisher]
Tue Jun 23, 2020 15:58
Related Articles Advances in the discovery and development of selective heme-displacing IDO1 inhibitors. Expert Opin Drug Discov. 2020 Jun 22;:1-10 Authors: Sun L Abstract INTRODUCTION: Indoleamine 2,3-dioxygenase 1 (IDO1) has been considered as an attractive intracellular target for the development of small-molecule cancer immunotherapy. Results in human clinical studies indicated that the first-generation IDO1 inhibitor epacadostat lacked...
Tue Jun 23, 2020 15:58
Related Articles Developments in the discovery and design of intranasal antidepressants. Expert Opin Drug Discov. 2020 Jun 21;:1-20 Authors: Panek M, Kawalec P, Pilc A, Lasoń W Abstract INTRODUCTION: Depression remains a major cause of morbidity worldwide; consequently, there is a need in neuropsychiatry for new antidepressants with a rapid onset of action. Intranasal administration of antidepressants is an attractive and promising approach...
Tue Jun 23, 2020 15:58
Related Articles Academy of Nutrition and Dietetics: 2020 Cystic Fibrosis Evidence Analysis Center Evidence-Based Nutrition Practice Guideline. J Acad Nutr Diet. 2020 Jun 18;: Authors: McDonald CM, Alvarez JA, Bailey J, Bowser EK, Farnham K, Mangus M, Padula L, Porco K, Rozga M Abstract The Academy of Nutrition and Dietetics Evidence Analysis Center conducted a systematic review of the literature to develop an evidence-based practice guideline...
Tue Jun 23, 2020 15:57
Related Articles Effects of Micronutrients or Conditional Amino Acids on COVID-19-Related Outcomes: An Evidence Analysis Center Scoping Review. J Acad Nutr Diet. 2020 May 20;: Authors: Rozga M, Cheng FW, Moloney L, Handu D Abstract Recent narrative reviews have described the potential efficacy of providing individuals infected with coronavirus disease 2019 (COVID-19) with additional micronutrients to reduce disease severity. Although there are...
Tue Jun 23, 2020 15:57
Related Articles Increasing Access to WIC through Discount Variety Stores: Findings from Qualitative Research. J Acad Nutr Diet. 2020 Jun 18;: Authors: Wallace LA, Morris VG, Hudak KM, Racine EF Abstract BACKGROUND: Many low-income neighborhoods do not include a full-service grocery store. In these communities, discount variety stores (DVS) can be convenient points of food access. However, no identified DVS are authorized to accept Special Supplemental...
Tue Jun 23, 2020 15:57
Related Articles Hiring Requirements and Qualifications of School Food Authority Directors Changed in Some Districts After Implementation of US Department of Agriculture Professional Standards. J Acad Nutr Diet. 2020 Jun 18;: Authors: Merlo CL, Tiu G, Wallace-Williams D, Brener ND, Figueroa H Abstract BACKGROUND: In 2015, the US Department of Agriculture set minimum education and training requirements (ie, professional standards) to ensure that...
Tue Jun 23, 2020 15:57
Related Articles Malnutrition Care During the COVID-19 Pandemic: Considerations for Registered Dietitian Nutritionists. J Acad Nutr Diet. 2020 May 14;: Authors: Handu D, Moloney L, Rozga M, Cheng FW Abstract Recent evidence examining adults infected with coronavirus disease 2019 (COVID-19) has indicated a significant impact of malnutrition on health outcomes. Individuals who have multiple comorbidities, are older adults, or who are malnourished,...
Tue Jun 23, 2020 15:57
Abstract Introduction Tumor treating fields (TTF) is a unique treatment modality that utilizes alternating electric fields to deliver therapy. Treatment effects have been assessed in patients with newly diagnosed and recurrent glioblastoma in clinical trials and retrospective studies. While the results of these studies led to FDA approval for both populations, a portion of the neuro-oncology and neurosurgery community remains skeptical...
Tue Jun 23, 2020 03:00
Related Articles Organization of biologic therapy during the COVID-19 pandemic based on example of Dermatology Clinic Centre of Postgraduate Medical Education in Warsaw. J Dermatolog Treat. 2020 Jun 22;:1-15 Authors: Dopytalska K, Mikucka-Wituszyńska A, Ciechanowicz P, Szczerba M, Szymańska E, Walecka I Abstract The COVID-19 pandemic spread to almost all countries in the world within a few months, necessitating changes in medical care for patients...
Tue Jun 23, 2020 15:38
Related Articles Psoriasis and COVID-19: a multifactorial consideration. J Dermatolog Treat. 2020 Jun 22;:1 Authors: Cohen JM, Perez-Chada LM, De Kouchkovsky D, Gehlhausen JR PMID: 32568011 [PubMed - as supplied by publisher]
Tue Jun 23, 2020 15:38
Related Articles Clinical management of psoriasis patients during the COVID-19 pandemic. J Dermatolog Treat. 2020 Jun 22;:1-2 Authors: Chat VS, Uppal SK, Kearns DG, Wu JJ Abstract Psoriasis is a systemic immune-mediated inflammatory disease that requires consistent treatment and follow-up. Given that COVID-19 will persist in the coming years, dermatologists need to adjust their practices accordingly to care for their patients, particularly psoriasis...
Tue Jun 23, 2020 15:38
Related Articles Comparative study between topical tranexamic acid alone versus its combination with autologous platelet rich plasma for treatment of melasma. J Dermatolog Treat. 2020 Jun 22;:1-7 Authors: Gamea MM, Kamal DA, Donia AA, Hegab DS Abstract Background: Tranexamic acid is a promising drug for melasma treatment, but its topical formulation has limited efficacy. Its use as liposome based cream or in combination with other modalities...
Tue Jun 23, 2020 15:38
Related Articles Phototherapy and vitamin D: the importance in COVID-19 era. J Dermatolog Treat. 2020 Jun 22;:1 Authors: Megna M, Fabbrocini G, Villani A PMID: 32567416 [PubMed - as supplied by publisher]
Tue Jun 23, 2020 15:38
Custom alloplastic temporomandibular joint (TMJ) reconstruction has been well established for the management of end-stage TMJ disease. However, its use in congenital TMJ deformities is limited. Here, the authors present initial outcomes of skeletally mature patients who underwent custom alloplastic TMJ reconstruction and simultaneous orthognathic surgery. A retrospective case series of patients who underwent custom alloplastic TMJ reconstruction concurrent with orthognathic surgery between 2014...
Thu Jun 18, 2020 03:00
Conditions that affect dental and periodontal structures receive sparse coverage in the plastic surgery literature, yet a working knowledge of this subject matter is important in certain areas of clinical practice and a fundamental understanding is part of plastic surgery competency tested on the in-service and written board examinations. This four-part series written to provide plastic surgeons with a working knowledge of dental topics that may be relevant to their clinical practice. This section,...
Thu Jun 18, 2020 03:00
Purpose: To introduce an easy and effective approach for internal fixation of repositioned fat pedicles in transconjunctival lower eyelid blepharoplasty. Methods: Thirty-six consecutive patients underwent fat repositioning transconjunctival lower blepharoplasty from August 2016 to January 2018. After release of the orbicularis oculi muscle and exposure of the intraorbital fat pedicles, a supraperiosteal pocket was dissected. A 6-0 nylon suture was passed through the shaft of a hypodermic...
Thu Jun 18, 2020 03:00
Localization of metastases into the parotid gland is a very uncommon event. Usually they arise from primary tumors located in the head and neck, mainly melanoma or epidermoid carcinoma of the skin, while other histotypes, from others anatomical districts, hardly have a metastatic spread to the parotid. Myxoid Liposarcoma (MLS) is a rare malignant tumor of the soft tissue that mainly occurs in the extremities, representing the second most common subtype of liposarcoma. Although it is typical for liposarcomas...
Thu Jun 18, 2020 03:00
In classical textbooks of Anatomy, the mental nerve is considered to be the terminal or main branch of the inferior alveolar nerve, especially trifurcate with no designated names as soon as it emerges from the mental foramen. The textbooks define the innervation area of the mental nerve regionally without naming its terminal branches. Nomina Anatomica designates 3 terminal branches of mental nerve as “labial, gingival, and mental branch” but offers no description about their distribution on the mandible....
Thu Jun 18, 2020 03:00
Objective: This study was aimed to obtain data on the dimensions of the optic foramen in human fetuses for early childhood surgeries. Methods: Twenty-five formalin-fixed fetuses (16 boys and 9 girls) with average age 21.68 ± 3.12 gestational weeks (range, 16–28 weeks) in the inventory of Anatomy Department, Faculty of Medicine were included in the study. The surface area, width, and height of the optic foramen were bilaterally measured using a digital image analysis software. Results:...
Thu Jun 18, 2020 03:00
Introduction: A cleft of the primary and/or secondary palate involve almost every function of the face except vision. Today, an isolate cleft palate or a complete cleft lip/palate should not be considered as an adverse condition because surgical repair has reached a highly satisfactory level. Nevertheless, for the average cleft surgeon palatoplasty still remains an enigma. Planning the Strategy: Having an observational and an anatomical measurement methodology of some pre op parameters,...
Thu Jun 18, 2020 03:00
Background: When determining whether a cleft lip repair outcome is acceptable, the severity of a patient's cleft at initial presentation must be considered. Currently, there is not a widely agreed upon scale for grading the pre-operative severity or post-operative surgical outcome for patients with unilateral and/or bilateral cleft lip. The aim of this study is to validate the Hubli grading system as a reliable and reproducible system for characterizing cleft lip repair outcomes. Methods:...
Thu Jun 18, 2020 03:00
Background: Presurgical nasoalveolar molding (NAM) is the most common preoperative treatment for cleft lip and palate. However, NAM may have some limitations such as requiring high technical sensitivity and frequent visits. To simplify the device, some scholars have changed the traditional NAM into a split-NAM consisting of a alveolar molding plate and a nasal hook. This study compared the shaping effect of split NAM and traditional NAM on nasolabial soft tissue using three-dimensional (3D)...
Thu Jun 18, 2020 03:00
Many factors govern the nature, severity, and outcome of missile war injuries and associated soft tissue damages. Managements of primary phase and trauma care have improved significantly. Many of these injured victims survived and require immediate care for primary phase management. Secondary phase was achieved by reconstruction of soft tissue by local, regional flaps, and bony defect by bone grafting. There is no consensus on timing of treatment of bone and soft tissue of missile war injuries....
Thu Jun 18, 2020 03:00
Roberts Syndrome is an extremely rare syndrome reporting about 150 cases in the literature, with a very low survival rate. The authors present a case of a female patient with Roberts Syndrome who also had a coronal craniosynostosis. The aim of this case report is to present a case of a patient with Roberts Syndrome with a brachycephaly that required management of fronto-orbital advancement. In conclusion Roberts Syndrome is a rare disease, which can have different skeletal variations. This syndrome...
Thu Jun 18, 2020 03:00
No abstract available
Thu Jun 18, 2020 03:00
Various resorbable plates and screws were used for facial bone fractures because of several strengths. However, there are few studies on their clinical course and long-term follow-up concerning their degradation and resorption time. The authors present rare case of long term follow-up of resorbable plates and screws under the incision site. Address correspondence and reprint requests to Jin Yong Shin, MD, Department of Plastic and Reconstructive Surgery, Jeonbuk National University Hospital....
Thu Jun 18, 2020 03:00
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