An efficient iodine-catalyzed three-component Mannich-type reaction of various 2-alkylfurans, methyl 2-formylbenzoates and carbamates under mild reaction conditions was realized. Synthetic utility of the resulting N-Boc-1-[2-(carbomethoxy)aryl]furfuryl amines was demonstrated by their facile two-step transformation into 2-methyl-6H-isochromeno[4,3-b]pyridin-6-ones employed in high-performance cyclometalated OLEDs.
from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2BgiFlX
No comments:
Post a Comment
Note: Only a member of this blog may post a comment.