SYK kinase mediates brown fat differentiation and activation

SYK kinase mediates brown fat differentiation and activation

SYK kinase mediates brown fat differentiation and activation, Published online: 13 December 2017; doi:10.1038/s41467-017-02162-3

Spleen protein tyrosine kinase (Syk) has so far been mainly studied in haematopoietic and immune cells. Here, the authors show that Syk also has a role in brown adipose tissue, where it regulates the formation of brown adipocytes and their thermogenic activation in response to β-adrenergic stimulation.

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