Osteopromotive Coatings: Diatom-Inspired Silica Nanostructure Coatings with Controllable Microroughness Using an Engineered Mussel Protein Glue to Accelerate Bone Growth on Titanium-Based Implants (Adv. Mater. 46/2017)

Silica nanoparticles can be utilized to construct nanostructures comprising surface topographic features and osteoinductivity. In article number 1704906, Chang Sup Kim, Hyung Joon Cha, and co-workers describe a diatom-inspired silica-nanoparticle nanostructure coating with controllable micro-roughness on titanium surfaces through the multilayer assembly of an organic–inorganic composite using an engineered silica-forming mussel protein glue, which enhances osteogenic cell behavior in a roughness-dependent manner, as well as promotes bone-tissue formation and maturation.

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