Blog Archive

Search This Blog

Thursday, December 6, 2018

Cardiac Denervation for Arrhythmia Treatment with Transesophageal Ultrasonic Strategy in Canine Models

Publication date: Available online 6 December 2018

Source: Ultrasound in Medicine & Biology

Author(s): Yuanqing Yao, Jun Qian, Shunkang Rong, Yuwen Huang, Bo Xiong, Gang Yang, Dengqing Zhang, Shimin Deng, Jie Tan, Que Zhu, Changming Deng, Dichuan Liu, Haitao Ran, Zhigang Wang, Jing Huang

Abstract

Stellate ganglion (SG) modification has been investigated for arrhythmia treatment. In this study, transesophageal SG imaging and intervention were explored using a homemade 30F integrated focused ultrasonic catheter in healthy mongrel canines in vivo. Anatomic details of SGs were ultrasonically imaged and evaluated. SG had a heterogeneous echoic structure and characteristic profiles sketched by hyper-echoic outlines in an ultrasonogram. Left SGs in the experimental group were successfully ablated through the esophagus under ultrasonic guidance provided by the catheter itself. Two weeks after the ablation, the QT and QTc of the experimental group decreased compared with those of the sham group and at baseline (both p values < 0.001). Histologic examination revealed that left SGs were destroyed. No major complications were observed. This approach may be further explored as a method for ganglia remodeling evaluation and as a strategy of ganglia modification for arrhythmia and for other diseases.



from Imaging via a.sfakia on Inoreader https://ift.tt/2RDQEcO

No comments:

Post a Comment

Note: Only a member of this blog may post a comment.

Blog Archive

Pages

   International Journal of Environmental Research and Public Health IJERPH, Vol. 17, Pages 6976: Overcoming Barriers to Agriculture Green T...