Abstract Alzheimer disease (AD) is one of the most prevalent progressive neurodegenerative diseases of the central nervous system. Regarding the anti-oxidant and neuroprotective effects of crocin, this research was conducted to determine the effect of crocin on apoptotic, inflammatory, brain-derived neurotrophic factor (BDNF), phospho tau protein (Pt), and Aβ40 (Amyloid beta40) indicators and neuronal density in CA1, CA2, and CA3 regions in hippocampus in the model of Alzheimer...
Abstract The aim of this study was to assess the effects of feeding aflatoxins on some reproductive hormones and on the composition of buffalo milk. Forty lactating buffaloes fed total mixed rations (TMR), part of which was contaminated by fungi secreting aflatoxin. The animals were divided into two equal groups: aflatoxin high group (AHG), animals were fed TMR containing aflatoxin > 21.2 ppb, and aflatoxin low one (ACG), buffaloes were fed on TMR containing aflatoxin < 5 ppb....
Abstract Platelet-rich fibrin (PRF) has gained more interests as an alternative modality for periodontal therapy due to its anti-inflammatory effect from platelet cytokines embedded in fibrin network. One of the factors that affect efficacy of PRF is the concentration of the incorporated cytokines. However, there is inadequate information regarding PRF preservation. Thus, this study was conducted to build on the knowledge in canine study regarding cytokine concentration and also...
Abstract In recent years, cutaneous wound healing by medicinal plants has been on the raise. In recent research, we appraised antioxidant, cytotoxicity, and cutaneous wound healing activities of Allium saralicum R.M. Fritsch aqueous extract ointment in rats. In this study, 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay was carried out to test the antioxidant property, which revealed high antioxidant potential similar to butylated hydroxytoluene (BHT) as a positive control. Synthesizing...
Abstract In our study, we evaluated cutaneous wound healing potential of Mentha piperita aqueous extract ointment in rats. In vivo design, after creating the cutaneous wound on the back of the rats, the animals were randomly divided into four groups: untreated control, treatment with Eucerin ointment, treatment with 3% tetracycline ointment, and treatment with 3% M. piperita aqueous extract ointment. The groups were treated for 30 days. For biochemical and histopathological analysis...
Abstract Cutaneous wound healing by medicinal plants which have fewer side effects than chemical drugs have been on the increase. In our study, we evaluated cutaneous wound healing potential of Allium eriophyllum Boiss aqueous extract ointment in rats. In in vivo design, after creating the cutaneous wound on the back of the rats, the animals were randomly divided into four groups: untreated control, treatment with Eucerin ointment, treatment with 3% tetracycline ointment, treatment...
Abstract The recent experiments have revealed the property of ethno-medicinal plants on the treatment of the cutaneous wound. The purpose of the experiment was to investigate the wound healing potential of Tragopogon graminifolius aqueous extract ointment. DPPH free radical scavenging test was carried out to examine the antioxidant effect of T. graminifolius aqueous extract, which indicated similar antioxidant activity with butylated hydroxy toluene (BHT) as a positive control....
Abstract A cross-sectional study was conducted to determine sero-prevalence of bluetongue virus (BTV) among of different ecological zones of Nepal. A total of 342 goat serum samples were tested by using c-ELISA for the presence of antibodies against BTV. Out of the total 342 serum samples tested, 130 were positive giving an overall sero-prevalence of 38.01%. Significantly higher sero-prevalence was found (p < 0.01) in Rupandehi District (65.11%) compared with Mustang District...
Abstract This study determined the gross morphometry and dimensions of the Red Sokoto goat (RSG) lungs, which may serve as basis for clinical and radiographic assessment of pulmonary consolidation. Seventy non-pneumonic RSG lungs were sampled comprising 44 males and 16 females, 12 of < 1 year, 30 between 1 and 2 years, and 18 > 2 years. Weight (gram), length (cm), and diameter (cm) of each lung lobe, distance from the tracheo-bronchus to the point of trachea bifurcation,...
Abstract Equine pancreatitis has no reliable ante-mortem test and is considered rare. The 1,2-o-dilauryl-rac-glycero-3-glutarate-(6′-methylresorufin) ester (DGGR) lipase assay is specific for pancreatic lipase (PL). It was developed for humans and validated in dogs, cats and rats as specific for pancreatitis diagnosis. We used a novel validation strategy to confirm this tissue specificity extended to horses and determine reference ranges and pancreatitis prevalence. One hundred...
Abstract The present study was designed to detect tick-borne hemoparasitic agents in 35 blood samples collected from healthy sheep from Lorestan province located in western Iran. Sheep blood samples were examined only using molecular method. By polymerase chain reaction (PCR), 13 (65%), 3 (15%), and one samples (5%) were to be infected by Anaplasma ovis, Theileria ovis, and Mycoplasma species, respectively. One sample from each positive target PCR was sequenced, successfully. This...
Abstract Guava (Psidium guajava Linn) is a common fruit tree in Nigeria with different species; the leaves, fruits, and the bark are often used in folklore for different medicinal purposes. However, there is a dearth of information on safety assessment of the leaves extract of guava from different species. These studies conducted toxicological evaluation of white, red, and pink guava leaves extract in rats for 14 days. Oral administration of 50, 500, and 5000 mg/kg BWT was carried...
Abstract Water pollution indices and oxidative stress biomarkers in African sharp-toothed catfish, Clarias gariepinus were used to evaluate the health status of Abereke River on the Ilaje coastal zone of Ondo’s Niger Delta region. Muscle and liver tissues from fishes harvested from the river and from a clean fish farm were comparatively subjected to heavy metal status and redox stress biomarker analyses. Water samples from the river and fish farm were also subjected to water quality...
Abstract In this report, concurrent infection of Leptospira interrogans serovar icterohaemorrhagiae, Hepatozoon canis and Anaplasma phagocytophilum in a Labrador Retriever dog and its successful therapeutic management have been described. A 3-year-old female dog was presented with a history of anorexia, fever, lethargy, weakness, vomiting, black-coloured faeces and yellowish urine. Clinical and laboratory examination revealed pyrexia, icteric mucous membranes, hepatomegaly, splenomegaly,...
Abstract We used TSA as a principal antigen of Leishmania major with adjuvants. The aim of this research was to assess the efficacy of protein vaccine in the presence of Montanide vis-à-vis chitosan nanoparticle. The expression of recombinant protein was confirmed with SDS (sodium dodecyl sulfate) page and Western blotting. A total of 36 BALB/c mice were divided into six groups (TSA/high chitosan, TSA/low chitosan, TSA/Montanide, high chitosan, low chitosan, and PBS groups) and...
Abstract Studies on canine respiratory diseases are scant in the literature especially in Africa, unlike the situation on ruminants. This study is on the pathology and bronchoalveolar cellular and oxidative stress changes in naturally occurring canine pneumonia in Nigeria. The dogs used were collected from cases submitted for necropsy in the institutional Department of Veterinary Pathology. Gross examination, bronchoalveolar lavage (BAL) cytology, oxidative biochemical assay of...
Abstract The effect of trypanosomosis (Trypanosoma brucei brucei and Trypanosoma congolense infection) and diminazene aceturate treatment on the epididymal function of male albino rats was investigated. Twenty-five adult male albino rats were used for this study. They were randomly assigned into 5 groups of 5 rats each. Group 1 was the uninfected untreated group while groups 2 and 3 were infected with 5 × 105T. congolense. Groups 4 and 5 were infected with 5 × 105T. brucei brucei....
Abstract Lungworms are considered one of the main causes of respiratory disorder in sheep worldwide that causes huge economic losses for the sheep industries. A cross-sectional study was carried out from March 2016 to April 2017 to characterize the pathological features and estimate the prevalence of lungworm infection in slaughtered sheep in Nangarhar Province of Afghanistan. Multiple emphysematic areas, white and consolidated spots and different sizes of nodules, and white–creamy...
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