Antibiotics, Vol. 9, Pages 624: Prevalence and Antibiotic Resistance of ESKAPE Pathogens Isolated in the Emergency Department of a Tertiary Care Teaching Hospital in Hungary: A 5-Year Retrospective Survey Antibiotics doi: 10.3390/antibiotics9090624 Authors: Ria Benkő Márió Gajdács Mária Matuz Gabriella Bodó Andrea Lázár Edit Hajdú Erika Papfalvi Peter Hannauer Péter Erdélyi Zoltán Pető Antibiotic treatments initiated on Emergency Departments (ED) are empirical....
Sat Sep 19, 2020 03:00
Antibiotics, Vol. 9, Pages 622: The Primary Care Perspective on the Norwegian National Strategy against Antimicrobial Resistance Antibiotics doi: 10.3390/antibiotics9090622 Authors: Guri Rørtveit Gunnar Skov Simonsen A national strategy to combat antimicrobial resistance (AMR) has been subject to cyclic processes in Norway since 1998. In 2020, a renewed process cycle was launched. Here, we describe the process and the approach of the process. In addition, we describe two concepts...
Sat Sep 19, 2020 03:00
Antibiotics, Vol. 9, Pages 621: Characterization of the Bacteriophage-Derived Endolysins PlySs2 and PlySs9 with In Vitro Lytic Activity against Bovine Mastitis Streptococcus uberis Antibiotics doi: 10.3390/antibiotics9090621 Authors: Niels Vander Elst Sara B. Linden Rob Lavigne Evelyne Meyer Yves Briers Daniel C. Nelson Bovine mastitis, an infection of the cow’s mammary gland, is frequently caused by Streptococcus uberis and causes major economic losses in the...
Sat Sep 19, 2020 03:00
Antibiotics, Vol. 9, Pages 620: Synergies with and Resistance to Membrane-Active Peptides Antibiotics doi: 10.3390/antibiotics9090620 Authors: Adam Kmeck Robert J. Tancer Cristina R. Ventura Gregory R. Wiedman Membrane-active peptides (MAPs) have long been thought of as the key to defeating antimicrobial-resistant microorganisms. Such peptides, however, may not be sufficient alone. In this review, we seek to highlight some of the common pathways for resistance, as well as some...
Sat Sep 19, 2020 03:00
Antibiotics, Vol. 9, Pages 623: Overcoming Intrinsic and Acquired Resistance Mechanisms Associated with the Cell Wall of Gram-Negative Bacteria Antibiotics doi: 10.3390/antibiotics9090623 Authors: Rachael E. Impey Daniel A. Hawkins J. Mark Sutton Tatiana P. Soares da Costa The global increase in multi-drug-resistant bacteria is severely impacting our ability to effectively treat common infections. For Gram-negative bacteria, their intrinsic and acquired resistance mechanisms...
Sat Sep 19, 2020 03:00
Antibiotics, Vol. 9, Pages 619: Amidochelocardin Overcomes Resistance Mechanisms Exerted on Tetracyclines and Natural Chelocardin Antibiotics doi: 10.3390/antibiotics9090619 Authors: Fabienne Hennessen Marcus Miethke Nestor Zaburannyi Maria Loose Tadeja Lukežič Steffen Bernecker Stephan Hüttel Rolf Jansen Judith Schmiedel Moritz Fritzenwanker Can Imirzalioglu Jörg Vogel Alexander J. Westermann Thomas Hesterkamp Marc Stadler Florian Wagenlehner Hrvoje...
Fri Sep 18, 2020 03:00
Antibiotics, Vol. 9, Pages 618: Antifungal Packaging Film to Maintain Quality and Control Postharvest Diseases in Strawberries Antibiotics doi: 10.3390/antibiotics9090618 Authors: Valentina Trinetta Austin McDaniel Konstantinos G. Batziakas Umut Yucel Londa Nwadike Eleni Pliakoni Strawberries are a highly perishable crop with postharvest losses than reach up to 40%. Cost-effective and sustainable technologies in the form of active packing films can provide a solution....
Fri Sep 18, 2020 03:00
Antibiotics, Vol. 9, Pages 617: Changes in Clinical Characteristics of Community-Acquired Acute Pyelonephritis and Antimicrobial Resistance of Uropathogenic Escherichia coli in South Korea in the Past Decade Antibiotics doi: 10.3390/antibiotics9090617 Authors: Ki Tae Kwon Bongyoung Kim Seong-yeol Ryu Seong-Heon Wie Jieun Kim Hyun-uk Jo Se Yoon Park Kyung-Wook Hong Hye In Kim Hyun ah Kim Mi-Hee Kim Mi Hyun Bae Yong-Hak Sohn Jieun Kim Yangsoon Lee Hyunjoo...
Fri Sep 18, 2020 03:00
Antibodies, Vol. 9, Pages 49: Molecular Mechanism of HER2 Rapid Internalization and Redirected Trafficking Induced by Anti-HER2 Biparatopic Antibody Antibodies doi: 10.3390/antib9030049 Authors: Jackie Cheng Meina Liang Miguel F. Carvalho Natalie Tigue Raffaella Faggioni Lorin K. Roskos Inna Vainshtein Amplification and overexpression of HER2 (human epidermal growth factor receptor 2), an ErbB2 receptor tyrosine kinase, have been implicated in human cancer and metastasis....
Fri Sep 18, 2020 03:00
Antioxidants, Vol. 9, Pages 891: Importance of the Use of Oxidative Stress Biomarkers and Inflammatory Profile in Aqueous and Vitreous Humor in Diabetic Retinopathy Antioxidants doi: 10.3390/antiox9090891 Authors: López-Contreras Martínez-Ruiz Olvera-Montaño Robles-Rivera Arévalo-Simental Castellanos-González Hernández-Chávez Huerta-Olvera Cardona-Muñoz Rodríguez-Carrizalez Diabetic retinopathy is one of the leading causes of visual impairment and...
Sun Sep 20, 2020 03:00
Antioxidants, Vol. 9, Pages 890: Microparticles-Mediated Vascular Inflammation and its Amelioration by Antioxidant Activity of Baicalin Antioxidants doi: 10.3390/antiox9090890 Authors: Keshav Raj Paudel Dong-Wook Kim Microparticles (MPs) are extracellular vesicles (0.1–1.0 μm in size), released in response to cell activation or apoptosis. Endothelial microparticles (EC-MP), vascular smooth muscle cell microparticles (VSMC-MP), and macrophage microparticles (MØ-MP)...
Sun Sep 20, 2020 03:00
Antioxidants, Vol. 9, Pages 889: Rats Genetically Selected for High Aerobic Exercise Capacity Have Elevated Plasma Bilirubin by Upregulation of Hepatic Biliverdin Reductase-A (BVRA) and Suppression of UGT1A1 Antioxidants doi: 10.3390/antiox9090889 Authors: Terry D. Hinds Justin F. Creeden Darren M. Gordon Adam C. Spegele Steven L. Britton Lauren G. Koch David E. Stec Exercise in humans and animals increases plasma bilirubin levels, but the mechanism by which this occurs...
Sat Sep 19, 2020 03:00
Antioxidants, Vol. 9, Pages 888: Allium Flavonols: Health Benefits, Molecular Targets, and Bioavailability Antioxidants doi: 10.3390/antiox9090888 Authors: Damini Kothari Woo-Do Lee Soo-Ki Kim Allium species are revered worldwide as vegetables, condiments, and spices as well as the therapeutic agents in traditional medicine. The bioactive compounds in alliums mainly include organosulfur compounds, polyphenols, dietary fibers, and saponins. Flavonoids, particularly flavonols from...
Sat Sep 19, 2020 03:00
Antioxidants, Vol. 9, Pages 887: Impairment of PGC-1 Alpha Up-Regulation Enhances Nitrosative Stress in the Liver during Acute Pancreatitis in Obese Mice Antioxidants doi: 10.3390/antiox9090887 Authors: Sergio Rius-Pérez Isabel Torres-Cuevas María Monsalve Francisco J. Miranda Salvador Pérez Acute pancreatitis is an inflammatory process of the pancreatic tissue that often leads to distant organ dysfunction. Although liver injury is uncommon in acute pancreatitis, obesity...
Sat Sep 19, 2020 03:00
Antioxidants, Vol. 9, Pages 886: A Short Overview of Changes in Inflammatory Cytokines and Oxidative Stress in Response to Physical Activity and Antioxidant Supplementation Antioxidants doi: 10.3390/antiox9090886 Authors: Shima Taherkhani Katsuhiko Suzuki Lindy Castell Excessive release of inflammatory cytokines and oxidative stress (OS) are triggering factors in the onset of chronic diseases. One of the factors that can ensure health in humans is regular physical activity. This...
Fri Sep 18, 2020 03:00
Antioxidants, Vol. 9, Pages 884: The Transcriptomic Response of the Murine Thyroid Gland to Iodide Overload and the Role of the Nrf2 Antioxidant System Antioxidants doi: 10.3390/antiox9090884 Authors: Dionysios V. Chartoumpekis Panos G. Ziros Ilias Georgakopoulos-Soares Adam A. T. Smith Ana Claudia Marques Mark Ibberson Peter A. Kopp Ioannis Habeos Ioannis P. Trougakos Nicholas K. H. Khoo Gerasimos P. Sykiotis Background: Thyroid follicular cells have physiologically...
Fri Sep 18, 2020 03:00
Antioxidants, Vol. 9, Pages 885: Retinoprotective Effect of Wild Olive (Acebuche) Oil-Enriched Diet against Ocular Oxidative Stress Induced by Arterial Hypertension Antioxidants doi: 10.3390/antiox9090885 Authors: Santana-Garrido Reyes-Goya Pérez-Camino André Mate Vázquez Oxidative stress plays an important role in the pathogenesis of ocular diseases, including hypertensive eye diseases. The beneficial effects of olive oil on cardiovascular diseases might rely on...
Fri Sep 18, 2020 03:00
Arts, Vol. 9, Pages 97: Interview with Yves Bouvier Arts doi: 10.3390/arts9030097 Authors: John Zarobell Yves Charles Edgar Bouvier is a founder and/or shareholder of the following firms: Expositions Natural le Coultre SA (Geneva), Fine Art Transports Natural le Coultre SA (Geneva), Le Freeport Management Pte Ltd (Singapore), The Singapore Freeport Real Estate Pte Ltd, The Luxembourg Freeport Management Company SA, The Luxembourg Freeport Real Estate SA, and Art Culture Studio SA (Geneva)...
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Atmosphere, Vol. 11, Pages 1005: Evaluation of Historical CMIP6 Model Simulations of Seasonal Mean Temperature over Pakistan during 1970–2014 Atmosphere doi: 10.3390/atmos11091005 Authors: Rizwan Karim Guirong Tan Brian Ayugi Hassen Babaousmail Fei Liu This work employed recent model outputs from coupled model intercomparison project phase six to simulate surface mean temperature during the June–July–August (JJA) and December–January–February...
Sun Sep 20, 2020 03:00
Atmosphere, Vol. 11, Pages 1004: Sensitivity of Simulated PM2.5 Concentrations over Northeast Asia to Different Secondary Organic Aerosol Modules during the KORUS-AQ Campaign Atmosphere doi: 10.3390/atmos11091004 Authors: Hyo-Jung Lee Hyun-Young Jo Chang-Keun Song Yu-Jin Jo Shin-Young Park Cheol-Hee Kim A numerical sensitivity study on secondary organic aerosol formation has been carried out by employing the WRF-Chem (Weather Research and Forecasting model coupled with...
Sun Sep 20, 2020 03:00
Atmosphere, Vol. 11, Pages 1003: Generalized Description of Intermittency in Turbulence via Stochastic Methods Atmosphere doi: 10.3390/atmos11091003 Authors: Jan Friedrich Rainer Grauer We present a generalized picture of intermittency in turbulence that is based on the theory of stochastic processes. To this end, we rely on the experimentally and numerically verified finding by R. Friedrich and J. Peinke [Phys. Rev. Lett. 78, 863 (1997)] that allows for an interpretation of the turbulent...
Sat Sep 19, 2020 03:00
Atmosphere, Vol. 11, Pages 1002: Advanced Global Model Ensemble Forecasts of Tropical Cyclone Formation, and Intensity Predictions along Medium-Range Tracks Atmosphere doi: 10.3390/atmos11091002 Authors: Elsberry Tsai Chin Marchok Marchok vortex tracker outputs from the European Centre for Medium-Range Weather Forecasts ensemble (ECEPS) and National Centers for Environmental Prediction ensemble (GEFS) are utilized to provide the Time-to-Formation (T2F of 25 kt or 35 kt)...
Fri Sep 18, 2020 03:00
Atmosphere, Vol. 11, Pages 1001: Future Projections for Wind, Wind Shear and Helicity in the Iberian Peninsula Atmosphere doi: 10.3390/atmos11091001 Authors: Martins Rocha Viceto Pereira Santos Wind is among the most important climatic elements. Its characteristics are determinant for a wide range of natural processes and human activities. However, ongoing climate change is modifying these characteristics, which may have important implications. Climatic changes on wind...
Fri Sep 18, 2020 03:00
Atmosphere, Vol. 11, Pages 1000: Application of the Hidden Markov Bayesian Classifier and Propagation Concept for Probabilistic Assessment of Meteorological and Hydrological Droughts in South Korea Atmosphere doi: 10.3390/atmos11091000 Authors: Muhammad Nouman Sattar Muhammad Jehanzaib Ji Eun Kim Hyun-Han Kwon Tae-Woong Kim Drought is one of the most destructive natural hazards and results in negative effects on the environment, agriculture, economics, and society. A meteorological...
Fri Sep 18, 2020 03:00
Atmosphere, Vol. 11, Pages 999: Spatial Variation and Trend of Extreme Precipitation in West Africa and Teleconnections with Remote Indices Atmosphere doi: 10.3390/atmos11090999 Authors: Samo Diatta Cheikh Waly Diedhiou Didier Maria Dione Soussou Sambou Extreme precipitation is a great concern for West Africa country, as it has serious consequence on key socio-economic activities. We use high resolution data from the Climate Hazards Group InfraRed Precipitation Stations (CHIRPS)...
Fri Sep 18, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 142: The Mediator Role of Body Image-Related Cognitive Fusion in the Relationship between Disease Severity Perception, Acceptance and Psoriasis Disability Behavioral Sciences doi: 10.3390/bs10090142 Authors: Vera Almeida Ângela Leite Diana Constante Rita Correia Isabel Filipa Almeida Maribel Teixeira Diogo Guedes Vidal Hélder Fernando Pedrosa e Sousa Maria Alzira Pimenta Dinis Ana Teixeira Psoriasis is a long-term skin disorder...
Sat Sep 19, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 141: Voluntary Language Switching in the Context of Bilingual Aphasia Behavioral Sciences doi: 10.3390/bs10090141 Authors: Nicholas Grunden Giorgio Piazza Carmen García-Sánchez Marco Calabria As studies of bilingual language control (BLC) seek to explore the underpinnings of bilinguals’ abilities to juggle two languages, different types of language switching tasks have been used to uncover switching and mixing effects and thereby...
Fri Sep 18, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 140: A Time-Lagged Examination of the Greenhaus and Allen Work-Family Balance Model Behavioral Sciences doi: 10.3390/bs10090140 Authors: Alfonso Landolfi Massimiliano Barattucci Alessandro Lo Presti The work-family interface is a compelling topic that calls into question labor market dynamics and work processes, together with important social and family composition changes. The present study aimed at examining the antecedents of Work-Family Balance...
Fri Sep 18, 2020 03:00
Biology, Vol. 9, Pages 301: Can Chitin and Chitosan Replace the Lichen Evernia prunastri for Environmental Biomonitoring of Cu and Zn Air Contamination? Biology doi: 10.3390/biology9090301 Authors: Loppi Vannini Monaci Dagodzo Blind Erler Fränzle This study compared the ability of the lichen Evernia prunastri, chitin and chitosan to take up Cu2+ and Zn2+. It was hypothesized that chitin and chitosan have an accumulation capacity comparable to the lichen, so that...
Sat Sep 19, 2020 03:00
Biology, Vol. 9, Pages 300: Effect of Sperm Concentration and Storage Temperature on Goat Spermatozoa during Liquid Storage Biology doi: 10.3390/biology9090300 Authors: Sara Sadeghi Raquel Del Gallego Balma García-Colomer Ernesto A. Gómez Jesús L. Yániz Jaime Gosálvez Carmen López-Fernández Miguel A. Silvestre The use of cooled semen is relatively common in goats. There are a number of advantages of cooled semen doses, including easier handling of artificial insemination...
Sat Sep 19, 2020 03:00
Biology, Vol. 9, Pages 297: Salt Stress-Induced Structural Changes Are Mitigated in Transgenic Tomato Plants Over-Expressing Superoxide Dismutase Biology doi: 10.3390/biology9090297 Authors: Bogoutdinova Lazareva Chaban Kononenko Dilovarova Khaliluev Kurenina Gulevich Smirnova Baranova Various abiotic stresses cause the appearance of reactive oxygen species (ROS) in plant cells, which seriously damage the cellular structures. The engineering of transgenic...
Fri Sep 18, 2020 03:00
Biology, Vol. 9, Pages 299: Pandæsim: An Epidemic Spreading Stochastic Simulator Biology doi: 10.3390/biology9090299 Authors: Patrick Amar Many methods have been used to model epidemic spreading. They include ordinary differential equation systems for globally homogeneous environments and partial differential equation systems to take into account spatial localisation and inhomogeneity. Stochastic differential equations systems have been used to model the inherent stochasticity of epidemic...
Fri Sep 18, 2020 03:00
Biology, Vol. 9, Pages 296: A Putative Prophylactic Solution for COVID-19: Development of Novel Multiepitope Vaccine Candidate against SARS-COV-2 by Comprehensive Immunoinformatic and Molecular Modelling Approach Biology doi: 10.3390/biology9090296 Authors: Rehman Mirza Ahmad Saleem Froeyen Ahmad Gul Alghamdi Aslam Sajjad Bhinder The outbreak of 2019-novel coronavirus (SARS-CoV-2) that causes severe respiratory infection (COVID-19) has spread...
Fri Sep 18, 2020 03:00
Biology, Vol. 9, Pages 295: Review on the Computational Genome Annotation of Sequences Obtained by Next-Generation Sequencing Biology doi: 10.3390/biology9090295 Authors: Girum Fitihamlak Ejigu Jaehee Jung Next-Generation Sequencing (NGS) has made it easier to obtain genome-wide sequence data and it has shifted the research focus into genome annotation. The challenging tasks involved in annotation rely on the currently available tools and techniques to decode the information contained...
Fri Sep 18, 2020 03:00
Biology, Vol. 9, Pages 298: Antioxidant, Antimicrobial, and Bioactive Potential of Two New Haloarchaeal Strains Isolated from Odiel Salterns (Southwest Spain) Biology doi: 10.3390/biology9090298 Authors: Patricia Gómez-Villegas Javier Vigara Marta Vila João Varela Luísa Barreira Rosa Léon The need to survive in extreme environments has furnished haloarchaea with a series of components specially adapted to work in such conditions. The possible application of these molecules...
Fri Sep 18, 2020 03:00
Biomedicines, Vol. 8, Pages 364: Capsaicin-Loaded Chitosan Nanocapsules for wtCFTR-mRNA Delivery to a Cystic Fibrosis Cell Line Biomedicines doi: 10.3390/biomedicines8090364 Authors: A. Katharina Kolonko Janes Efing Yadira González-Espinosa Nadine Bangel-Ruland Willy van Driessche Francisco M. Goycoolea Wolf-Michael Weber Cystic fibrosis (CF), a lethal hereditary disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene coding...
Sun Sep 20, 2020 03:00
Biomedicines, Vol. 8, Pages 365: Effect of Hypoxia Preconditioned Secretomes on Lymphangiogenic and Angiogenic Sprouting: An in Vitro Analysis Biomedicines doi: 10.3390/biomedicines8090365 Authors: Philipp Moog Rahmin Schams Alexander Schneidinger Arndt F. Schilling Hans-Günther Machens Ektoras Hadjipanayi Ulf Dornseifer Hypoxia Preconditioned Plasma (HPP) and Serum (HPS) are two blood-derived autologous growth factor compositions that are being clinically employed...
Sun Sep 20, 2020 03:00
Biomedicines, Vol. 8, Pages 363: Impact of Subclinical Congestion on Outcome of Patients Undergoing Mitral Valve Surgery Biomedicines doi: 10.3390/biomedicines8090363 Authors: Anne-Kristin Schaefer Thomas Poschner Martin Andreas Alfred Kocher Günther Laufer Dominik Wiedemann Markus Mach Since risk assessment prior to cardiac surgery is based on proven but partly unsatisfactory scores, the need for novel tools in preoperative risk assessment taking into account cardiac...
Sat Sep 19, 2020 03:00
Biomedicines, Vol. 8, Pages 362: Protein Dynamics in F-like Bacterial Conjugation Biomedicines doi: 10.3390/biomedicines8090362 Authors: Nicholas Bragagnolo Christina Rodriguez Naveed Samari-Kermani Alice Fours Mahboubeh Korouzhdehi Rachel Lysenko Gerald F. Audette Efficient in silico development of novel antibiotics requires high-resolution, dynamic models of drug targets. As conjugation is considered the prominent contributor to the spread of antibiotic resistance...
Sat Sep 19, 2020 03:00
Biomedicines, Vol. 8, Pages 361: Dibenzoylthiamine Has Powerful Antioxidant and Anti-Inflammatory Properties in Cultured Cells and in Mouse Models of Stress and Neurodegeneration Biomedicines doi: 10.3390/biomedicines8090361 Authors: Margaux Sambon Anna Gorlova Alice Demelenne Judit Alhama-Riba Bernard Coumans Bernard Lakaye Pierre Wins Marianne Fillet Daniel C. Anthony Tatyana Strekalova Lucien Bettendorff Thiamine precursors, the most studied being benfotiamine...
Fri Sep 18, 2020 03:00
Biomedicines, Vol. 8, Pages 360: COL2A1 Is a Novel Biomarker of Melanoma Tumor Repopulating Cells Biomedicines doi: 10.3390/biomedicines8090360 Authors: Bhavana Talluri Kshitij Amar Michael Saul Tasnim Shireen Vjollca Konjufca Jian Ma Taekjip Ha Farhan Chowdhury Soft 3D-fibrin-gel selected tumor repopulating cells (TRCs) from the B16F1 melanoma cell line exhibit extraordinary self-renewal and tumor-regeneration capabilities. However, their biomarkers and gene regulatory...
Fri Sep 18, 2020 03:00
Biomedicines, Vol. 8, Pages 359: A Multi-Omics Approach Reveals New Signatures in Obese Allergic Asthmatic Children Biomedicines doi: 10.3390/biomedicines8090359 Authors: Mª Amelia Gomez-Llorente Ana Martínez-Cañavate Natalia Chueca Mª de la Cruz Rico Raquel Romero Augusto Anguita-Ruiz Concepción Mª Aguilera Mercedes Gil-Campos Maria D Mesa Bekzod Khakimov Jose Antonio Morillo Ángel Gil José Camacho Carolina Gomez-Llorente Background: Asthma is...
Fri Sep 18, 2020 03:00
Biomolecules, Vol. 10, Pages 1345: Lipophilic Cations Rescue the Growth of Yeast under the Conditions of Glycolysis Overflow Biomolecules doi: 10.3390/biom10091345 Authors: Svyatoslav S. Sokolov Ekaterina A. Smirnova Olga V. Markova Natalya A. Kireeva Roman S. Kirsanov Liudmila S. Khailova Dmitry A. Knorre Fedor F. Severin Chemicals inducing a mild decrease in the ATP/ADP ratio are considered as caloric restriction mimetics as well as treatments against obesity....
Sun Sep 20, 2020 03:00
Biomolecules, Vol. 10, Pages 1343: Molecular Topology for the Discovery of New Broad-Spectrum Antibacterial Drugs Biomolecules doi: 10.3390/biom10091343 Authors: Jose I. Bueso-Bordils Pedro A. Alemán-López Beatriz Suay-Garcia Rafael Martín-Algarra Maria J. Duart Antonio Falcó Gerardo M. Antón-Fos In this study, molecular topology was used to develop several discriminant equations capable of classifying compounds according to their antibacterial activity. Topological...
Sat Sep 19, 2020 03:00
Biomolecules, Vol. 10, Pages 1344: 5-Hydroxytryptamine (5-HT) Positively Regulates Pigmentation via Inducing Melanoblast Specification and Melanin Synthesis in Zebrafish Embryos Biomolecules doi: 10.3390/biom10091344 Authors: Li Liu Min Zhong Jing Dong Minghan Chen Jing Shang Yunyun Yue It has been reported that 5-hydroxytryptamine (5-HT) is related to melanogenesis in mice and melanoma cells. However, the underlying mechanisms of 5-HT in regulating pigmentation remains...
Sat Sep 19, 2020 03:00
Biomolecules, Vol. 10, Pages 1342: Cryo-EM Structure of Heterologous Protein Complex Loaded Thermotoga Maritima Encapsulin Capsid Biomolecules doi: 10.3390/biom10091342 Authors: Xiansong Xiong Chen Sun Frank S. Vago Thomas Klose Jiankang Zhu Wen Jiang Encapsulin is a class of nanocompartments that is unique in bacteria and archaea to confine enzymatic activities and sequester toxic reaction products. Here we present a 2.87 Å resolution cryo-EM structure of Thermotoga...
Sat Sep 19, 2020 03:00
Biomolecules, Vol. 10, Pages 1336: Triapine Derivatives Act as Copper Delivery Vehicles to Induce Deadly Metal Overload in Cancer Cells Biomolecules doi: 10.3390/biom10091336 Authors: Kateryna Ohui Iryna Stepanenko Iuliana Besleaga Maria V. Babak Radu Stafi Denisa Darvasiova Gerald Giester Vivien Pósa Eva A. Enyedy Daniel Vegh Peter Rapta Wee Han Ang Ana Popović-Bijelić Vladimir B. Arion Thiosemicarbazones continue to attract the interest of researchers...
Sat Sep 19, 2020 03:00
Biomolecules, Vol. 10, Pages 1340: Evaluation of the Adverse Effects of Chronic Exposure to Donepezil (An Acetylcholinesterase Inhibitor) in Adult Zebrafish by Behavioral and Biochemical Assessments Biomolecules doi: 10.3390/biom10091340 Authors: Gilbert Audira Nguyen Thi Ngoc Ngoc Anh Bui Thi Ngoc Ngoc Hieu Nemi Malhotra Petrus Siregar Omar Villalobos Oliver B. Villaflores Tzong-Rong Ger Jong-Chin Huang Kelvin H.-C. Chen Chung-Der Hsiao Donepezil (DPZ)...
Fri Sep 18, 2020 03:00
Biomolecules, Vol. 10, Pages 1339: Pompe Disease: New Developments in an Old Lysosomal Storage Disorder Biomolecules doi: 10.3390/biom10091339 Authors: Naresh K. Meena Nina Raben Pompe disease, also known as glycogen storage disease type II, is caused by the lack or deficiency of a single enzyme, lysosomal acid alpha-glucosidase, leading to severe cardiac and skeletal muscle myopathy due to progressive accumulation of glycogen. The discovery that acid alpha-glucosidase resides in...
Fri Sep 18, 2020 03:00
Biomolecules, Vol. 10, Pages 1341: Metabolic Diversity and Therapeutic Potential of Holarrhena pubescens: An Important Ethnomedicinal Plant Biomolecules doi: 10.3390/biom10091341 Authors: Kulsoom Zahara Sujogya Kumar Panda Shasank Sekhar Swain Walter Luyten Holarrhena pubescens is an important medicinal plant of the Apocynaceae family that is widely distributed over the Indian subcontinent. The plant is extensively used in Ayurveda and other traditional medicinal systems without...
Fri Sep 18, 2020 03:00
Biomolecules, Vol. 10, Pages 1337: The Cytokine IL-1β and Piperine Complex Surveyed by Experimental and Computational Molecular Biophysics Biomolecules doi: 10.3390/biom10091337 Authors: Gabriel Zazeri Ana Paula Ribeiro Povinelli Marcelo de Freitas Lima Marinônio Lopes Cornélio The bioactive piperine, a compound found in some pepper species, has been widely studied because of its therapeutic properties that include the inhibition of an important inflammation pathway triggered...
Fri Sep 18, 2020 03:00
Biomolecules, Vol. 10, Pages 1338: Production of Aromatic Compounds by Catalytic Depolymerization of Technical and Downstream Biorefinery Lignins Biomolecules doi: 10.3390/biom10091338 Authors: Alfonso Cornejo Fernando Bimbela Rui Moreira Karina Hablich Íñigo García-Yoldi Maitane Maisterra António Portugal Luis M. Gandía Víctor Martínez-Merino Lignocellulosic materials are promising alternatives to non-renewable fossil sources when producing aromatic compounds....
Fri Sep 18, 2020 03:00
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