Hepatocellular carcinoma is the second leading cause of cancer-related death worldwide. Neural regulation plays an important role in the development of hepatocellular carcinoma, and activation of sympathetic nervous system can promote the migration and invasion of cancer cells. However, little research has been conducted on how the vagus nerve influences hepatocellular carcinoma. In this study, we found that the expression of vesicular acetylcholine transporter, a biomarker of vagus nerve, was associated...
Fri Sep 18, 2020 21:19
Since the introduction of antiepidermal growth factor receptor (anti-EGFR) monoclonal antibodies (moAbs), the treatment of metastatic colorectal cancer (mCRC) has become crucially dependent on the mutation profile of the tumour over the last two decades. Recently, rechallenge strategy with cetuximab-based chemotherapy has demonstrated to be active in a subgroup of patients whose tumour maintained wild-type RAS and RAF status. In this setting, liquid biopsy may replace tissue sample for the identification...
Fri Sep 18, 2020 21:19
Gliomas are the most common and aggressive type of primary brain cancer in adults. The expression of transmembrane protein 45A (TMEM45A) in glioma patients and glioma cell lines was analyzed by quantitative real-time PCR. The influence of TMEM45A on the survival of glioma patients was also explored in this study. To verify the interaction between TMEM45A and key genes, correlation analysis of expression levels and the siRNA knock down method were performed. TMEM45A was upregulated in glioma tissues,...
Fri Sep 18, 2020 21:19
In the present study, to delve into the effect of granulocyte-macrophage colony-stimulating factor (GM-CSF) combined with temozolomide (TMZ) on high-grade glioma cells and related mechanism, six cases of high-grade glioma cells from patient’s tumor tissues were cultured. 3-(4,5)-dimethylthiahiazo (-z-y1)-3,5-di- phenytetrazoliumromide 3-(4,5)-dimethylthiahiazo (-z-y1)-3,5-di- phenytetrazoliumromide (MTT) assay was performed to detect cell proliferation and toxicity. Flow cytometry was performed to...
Fri Sep 18, 2020 21:19
With unique advantages, the small-molecule anticancer drugs have recently gained growing attention. Particular strategies, exemplified by high-throughput screening, fragment-based drug discovery, virtual screening and knowledge-based design, have been developed to identify active compounds. However, such screens generally rely on sophisticated and expensive instrumentations. Herein, we developed a simple spheroids 3D culture system to enable direct screening of small molecules with reliable results....
Fri Sep 18, 2020 21:19
To evaluate the predictive value of preoperative biochemical marker [platelet-to-lymphocyte ratio (PLR)] in patients with advanced hepatocellular cancer receiving transarterial chemoembolization (TACE) plus targeted molecular therapy (apatinib) treatment. Clinical records of 134 patients receiving the treatment of TACE + apatinib (TACE-A) and the treatment of TACE alone were compared in a single-center study. Time to progression (TTP) and overall survival (OS) were compared between TACE-A and TACE...
Fri Sep 18, 2020 21:19
Heparanase is an endoglycosidase that degrades heparan sulfate side chains of heparan sulfate-proteoglycans. It liberates heparan sulfate-bound growth factors and thereby promotes blood vessel sprouting and angiogenesis. The subterranean blind mole rat, Spalax, is a wild mammal that lives most of its life in underground tunnels where it experiences sharp fluctuations in oxygen and carbon dioxide levels. We described two splice variants of heparanase from Spalax, Splice 7 and splice 36, both devoid...
Fri Sep 18, 2020 21:19
Zusammenfassung Die „Qualitätssicherung-Initiative Pathologie“ (QuIP) bietet den Pathologen die Möglichkeit, die methodischen Abläufe der immunhistologischen und molekularen Diagnostik ergebnisorientiert überprüfen und zertifizieren zu lassen. Für die In-situ-Hybridisierungs- (ISH-)Diagnostik wurden 2019 5 Ringversuche angeboten, 2 wiederkehrende (HER2-ISH-Magenkarzinome und HER2-ISH-Mammakarzinome) sowie 3 prototypische (ROS1-NSCLC, ALK1-NSCLC, NTRK). Dabei richten sich die angebotenen...
Fri Sep 18, 2020 03:00
Summary Background Depression is frequently underdiagnosed and insufficiently treated in psoriatic patients in their daily routine. The aim of this study was to screen and analyze the impact of patient and disease characteristics on depression scores. Patients and Methods In this cross‐sectional multicenter cohort study, adult psoriasis patients were screened for depression with two validated tools: the Whooley questions and the revised Beck Depression Inventory (BDI‐II). Results Overall,...
Fri Sep 18, 2020 13:14
Summary Optical coherence tomography (OCT) is a non‐invasive, high‐resolution imaging technique with a growing impact in dermatology. The principle of OCT is comparable to that of sonography, except that it uses infrared laser light instead of ultrasound waves. It has been clinically demonstrated that OCT is suitable for discriminating between different types of non‐melanoma skin cancer at an early stage of disease. Optical coherence tomography generates two‐ or three‐dimensional images of up to...
Fri Sep 18, 2020 13:20
Objective: The aim of this study was to evaluate the feasibility and safety of transcanal underwater endoscopic bone resection (TUEBR) of the external auditory canal (EAC) for the management of cholesteatoma involving the antrum and mastoid. Study Design: Retrospective case review. Setting: Tertiary referral center. Patients: Pediatric and adult patients with primary cholesteatoma extending to the antrum and mastoid who underwent transcanal endoscopic ear surgery (TEES) with TUEBR...
Thu Sep 17, 2020 03:00
Objective: To compare the treatment outcomes and complications of single cycle versus multiple cycles of the canalith repositioning procedure (CRP). Study Design: Randomized controlled trial. Setting: Academic tertiary referral center; Chiang Mai University, Thailand. Patients: One hundred and forty-three adults who had unilateral posterior canal benign paroxysmal positional vertigo (BPPV). Intervention: Therapeutic. Patients received either a single cycle or multiple cycles...
Thu Sep 17, 2020 03:00
Majid A Almadi, Abdulrahman M Aljebreen, Nahla Azzam, Faisal BatwaSaudi Journal of Gastroenterology 2020 26(5):285-286
Fri Sep 18, 2020 00:00
Nahla A Azzam, Abdulrahman Aljebreen, Arwa Almuhareb, Majid A AlmadiSaudi Journal of Gastroenterology 2020 26(5):256-262 Background/Aim: Inflammatory bowel disease (IBD) is a chronic disorder affecting patients' health-related quality of life (HRQoL) which adds to their disability. Little is known about the impact of the COVID-19 pandemic on HRQoL of IBD patients. We aimed to evaluate HRQoL in IBD patient's pre- and post-COVID-19 pandemic using the IBD-disk questionnaire and explore associations...
Fri Sep 18, 2020 00:00
Nahla Azzam, Nora Alotaibi, Majid Almadi, Abdulrahman AljebreenSaudi Journal of Gastroenterology 2020 26(5):279-282
Fri Sep 18, 2020 00:00
The psychological impact of COVID-19 pandemic on physicians in Saudi Arabia: A cross-sectional study
Eman Al Sulais, Mahmoud Mosli, Turki AlAmeelSaudi Journal of Gastroenterology 2020 26(5):249-255 Background/Aim: COVID-19 pandemic exposed physicians to extraordinary stress and made them vulnerable to various types of psychological illnesses. The aim of this study was to evaluate the impact that the COVID-19 pandemic had on the psychological well-being of physicians. Materials and Methods: We performed a cross-sectional, survey-based study, targeting physicians in Saudi Arabia during the COVID-19...
Fri Sep 18, 2020 00:00
Mahmoud Mosli, Mansour Alourfi, Amani Alamoudi, Almoutaz Hashim, Omar Saadah, Eman Al Sulais, Turki AlAmeel, Othman Alharbi, Shakir Bakari, Yaser Meeralam, Seigha Alshobai, Majid Alsahafi, Hani Jawa, Yousif QariSaudi Journal of Gastroenterology 2020 26(5):263-271 Background/Aims: The coronavirus (COVID-19) pandemic has caused significant disruption to patients with chronic illnesses. We explored the emotional state, perception, and concerns of Saudi patients with inflammatory bowel disease (IBD)...
Fri Sep 18, 2020 00:00
Majid A Almadi, Abdulrahman M Aljebreen, Nahla Azzam, Nuha Alammar, Emad S Aljahdli, Fahad I Alsohaibani, Resheed Alkhiari, Abdulaziz O Almasoud, Mohammad S Al Beshir, Suliman Alshankiti, Ahmad W Alharbi, Mohammed Alkhathami, Faisal BatwaSaudi Journal of Gastroenterology 2020 26(5):240-248 With the global pandemic due to coronavirus disease 2019 (COVID-19), there has been a significant strain on healthcare facilities. The infectivity rate, as well as the rate of healthcare workers who have fallen...
Fri Sep 18, 2020 00:00
Ahmad S Almalki, Mohammed Khan, Turki AlAmeelSaudi Journal of Gastroenterology 2020 26(5):283-284
Fri Sep 18, 2020 00:00
Bandar Al-Judaibi, Reem Almaghrabi, Mohammed Alghamdi, Waleed K Al-Hamoudi, Mohammed AlQahtani, Faisal Abaalkhail, Mohammed Shagrani, Faisal M SanaiSaudi Journal of Gastroenterology 2020 26(5):233-239 The World Health Organization (WHO), on March 11th 2020, upgraded the status of the novel coronavirus disease (COVID-19) from epidemic to pandemic. Over two million individuals have been infected with SARS-CoV-2, the virus causing COVID-19, and as of April, 14th 2020, there were over 5000 confirmed...
Fri Sep 18, 2020 00:00
Eric M Yoshida, Trana Hussaini, Majid AlsahafiSaudi Journal of Gastroenterology 2020 26(5):223-225
Fri Sep 18, 2020 00:00
Janice Cheong, Nichoals Bartell, Thoetchai Peeraphatdit, Mahmoud Mosli, Bandar Al-JudaibiSaudi Journal of Gastroenterology 2020 26(5):226-232 The novel coronavirus 2 (SARS-CoV-2) has spread worldwide. While patients typically present with fever and symptoms of a respiratory illness, patients have also presented with gastrointestinal symptoms such as diarrhea, vomiting and abdominal pain. In addition, some patients were reported to have liver injury. In this article, we review gastrointestinal and...
Fri Sep 18, 2020 00:00
Tao Li, Ying Guo, Xianghua Zhuang, Laigang Huang, Xingqian Zhang, Fengtao Wei, Baohua YangSaudi Journal of Gastroenterology 2020 26(5):272-278 Background/Aims: We aimed to evaluate the distribution of abnormal liver-related biomarkers in patients with coronavirus disease (COVID-19) and explore the prognostic value of elevated liver enzymes and abnormal liver synthetic capacity with regards to patient mortality. Patients and Methods: This retrospective observational study included 80 laboratory-confirmed...
Fri Sep 18, 2020 00:00
Introduced in 2010, transoral robotic surgery (TORS) is recognized as an effective treatment of moderate to severe obstructive sleep apnea (OSA) in the setting of lymphoid and muscular tongue base hypertrophy. Upper airway stimulation (UAS) or hypoglossal nerve stimulation has emerged as a promising treatment of patients with moderate to severe OSA who have failed continuous positive airway pressure. UAS has shown favorable success rates and low morbidity compared with traditional soft tissue and...
Fri Sep 18, 2020 03:00
Unknown primary squamous cell carcinoma metastatic to cervical lymph nodes is a relatively rare tumor presentation, although the incidence may be increasing along with the rising incidence of human papilloma virus–mediated oropharyngeal cancers. Traditional diagnostic methods with palatine tonsillectomy and panendoscopy may identify the minority of primary tumors. The addition of a transoral lingual tonsillectomy may improve the diagnostic yield of identifying a primary tumor. Incorporation of transoral...
Fri Sep 18, 2020 03:00
There are numerous salivary gland pathologies for which robotic surgery can provide benefit. This article reviews the primary indications for use of transoral robotic surgery for salivary gland neoplasms. It also discusses transoral and retroauricular robotic approaches for pathology of the submandibular gland and prestyloid parapharyngeal space. These approaches have the advantage of avoiding a visible scar and are additionally minimally invasive in other ways as well. Robotic surgery offers advantages...
Fri Sep 18, 2020 03:00
Horror entertainment is a thriving and paradoxical industry. Who are the consumers of horror, and why do they seek out frightening media? We provide support for the threat simulation theory of horror, according to which horror media provides a form of benign masochism that offers negative emotional stimulation through simulation of threat scenarios. Through an online survey of genre use and preference as well as personality traits and paranormal beliefs (n = 1,070), we find that sensation seeking...
Mon Nov 26, 2018 07:00
Intrinsic to an evolved disease avoidance account of disgust is Darwin’s assumption of continuity between the emotional lives of humans and animals. However, beyond the case of avoiding stimuli that taste bad, there has been little exploration of the existence of basic disgust elicitors in animals. Moreover, one influential perspective holds that disgust is unique to humans—a preadaptation of distaste that expands through culture to include a wide range of elicitors (e.g., Rozin, 2015). The present...
Thu May 23, 2019 07:00
People often experience anger and/or disgust when observing wrongdoings. It is considered that anger and disgust elicited by moral violations are associated with different social functions: Anger motivates direct punishment and disgust motivates indirect punishment. However, within the domain of morality, some scholars question the distinctness of anger and disgust and doubt the relevance of disgust to moral judgments. By reanalyzing data from a previous study, we first confirmed that self-reported...
Mon Jul 15, 2019 07:00
Previous studies have highlighted the influence of conditional mating strategies in attractiveness preferences. “Good genes” and dominance cues are perceived as attractive when considering short-term relationships. In contrast, cues for better parenting abilities and trustworthiness are considered more attractive when participants ponder a long-term relationship. We investigated women’s and men’s attractiveness preferences in other-sex faces that were structurally altered along a continuum of apparent...
Thu Jul 25, 2019 07:00
Using evolutionary theories related to bullying, resource control, and reciprocal altruism as guiding frameworks, this study examined how bullying perpetration, bullying victimization, and prosocial resource control strategies were associated with two distinct indicators of the ability to acquire resources—dominance and alliance formation. Adolescents (N = 396; Mage = 14.64, SDage = 1.52; 58% girls) completed self-report measures on bullying perpetration and victimization, prosocial strategies, dominance,...
Mon Aug 05, 2019 07:00
Image description: A woman with grey-silver hair stands in front of a bright teal green wall. She wears a pink bandanna on her head, sunglasses, and a blue shirt.Caption: Rose-Marie Chierici 1942–2020 Rose-Marie Chierici, 78, died in Rochester, New York, on August 14, 2020. Born in Port-au-Prince, Haiti, in 1942, Chierici was the eldest of 12 children. Her family relocated to Washington, DC, in 1960 and she matriculated at George Washington University in 1961. She received her BS in zoology...
Fri Sep 18, 2020 23:10
Image description: A man with a white mustache wearing glasses and a green plaid shirt smiles at the camera. Caption: William Taft Stuart 1939–2020 William Taft Stuart was born on April 12, 1939, in Hornell, New York. He died on August 13, 2020, in Myrtle Beach, South Carolina. He is remembered for his dedication to his students, and his warm collegiality toward his colleagues. Stuart earned his BA in sociology in 1961 from The George Washington University. He earned his PhD in anthropology from...
Fri Sep 18, 2020 23:11
Image description: A woman with dark brown and grey hair wears a light brown blazer and cream colored shirt. She stands outside during the day and smiles with her arms crossed. In the distance behind her, there are people, trees, and a brick building.Caption: Sally Engle Merry. ©Thomas: Courtesy of NYU Photo Bureau 1945–2020 In life, Sally Engle Merry was a charismatic presence and a clarion voice in the profession, championing anthropology and especially the students and scholars ready to take...
Fri Sep 18, 2020 23:12
LaryngorhinootologieDOI: 10.1055/a-1253-8279Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals:Table of contents | Full text
Fri Sep 18, 2020 02:00
LaryngorhinootologieDOI: 10.1055/a-1253-8325 Hintergrund Die Hörgeräteversorgung stellt die Standardtherapie zur Behandlung von Schwerhörigkeit dar, die von der gesetzlichen Krankenversicherung (GKV) getragen wird. Bei chronischem Verlauf entstehen dabei Kosten bis zum Lebensende des Patienten. Die vorliegende Analyse untersucht die durchschnittlichen Lebenszeitkosten der Hörgeräteversorgung erwachsener Patienten in Abhängigkeit des Erstversorgungsalters und stellt diese sowohl aus Perspektive...
Fri Sep 18, 2020 02:00
Related Articles A Puzzling Exam: Kernohan's Notch Reimaged. J Clin Neurosci. 2020 Sep 14;: Authors: Carlstrom LP, Perry A, Puffer RC, Graffeo CS, Reuter PJ, Fogelson JL, Wijdicks EF PMID: 32938557 [PubMed - as supplied by publisher]
Sat Sep 19, 2020 02:55
Exp Clin Endocrinol DiabetesDOI: 10.1055/a-1242-9809Type 2 diabetes mellitus is a heterogeneous disease. Recently introduced new subclassifications promise more efficacious, tailored treatments which could complement current guidelines. In the differentiation of the new diabetes subphenotypes, assessment of insulin secretion is one of the essential components. Based on a large number of insulin secretion measurements,...
Fri Sep 18, 2020 02:00
Thorac Cardiovasc Surg Rep 2020; 09: e44-e46DOI: 10.1055/s-0040-1714074 Background Postinfarction ventricular septal defect (VSD) is a rare but life-threatening complication of acute myocardial infarction (AMI). Surgery represents the treatment of choice. But the optimal timing for surgery is still under debate. Case Description Here, we present the case of a 70-year-old female patient with an anterior postinfarction VSD leading to cardiogenic shock for whom we used a percutaneous...
Fri Sep 18, 2020 02:00
Thorac Cardiovasc Surg Rep 2020; 09: e33-e36DOI: 10.1055/s-0040-1714075Myasthenia gravis and thymoma are often presented in association with ∼10% of myasthenic cases having concomitant thymoma. Thymic carcinoma is one of the rarest/aggressive human epithelial tumors and has no correlation with myasthenia gravis hitherto. Here is provided a clinical case and review of literature on a very rare association of thymic carcinoma (with no sign of thymoma) and myasthenia gravis (antiacetylcholine receptor...
Fri Sep 18, 2020 02:00
Thorac Cardiovasc Surg Rep 2020; 09: e40-e43DOI: 10.1055/s-0040-1715183 Background Intravenous leiomyomatosis is a rare disease. Histologically, intravenous leiomyomatosis is a benign tumor, but its biological behavior can be malignant. The development of intracardiac extensions leads to congestive heart failure and occasionally sudden fatalities. Case Description The cases of three patients treated at our university between 2017 and 2018 were studied retrospectively. Intravenous...
Fri Sep 18, 2020 02:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c06399
Thu Sep 17, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c05636
Fri Sep 18, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07726
Fri Sep 18, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07357
Fri Sep 18, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c09083
Fri Sep 18, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c06925
Fri Sep 18, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07651
Fri Sep 18, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c05765
Fri Sep 18, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c03405
Thu Sep 17, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01426
Fri Sep 18, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c02755
Fri Sep 18, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c02810
Fri Sep 18, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c03775
Fri Sep 18, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c02780
Fri Sep 18, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c03312
Fri Sep 18, 2020 07:00
Chin wing osteotomy (CWO) is a technical refinement of genioplasty that extends the osteotomy posteriorly to the mandibular posterior border underneath the mandibular canal.1 It enables versatile corrections of the mandibular contour and highly aesthetic outcomes.
Fri Sep 18, 2020 03:00
The true impact and long-term damage to organs such as the lungs following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remain to be determined. Non-invasive molecularly targeted imaging may play a critical role to aid in the visualization and understanding of the systemic damage. We have identified αvβ6 as molecular target; an epithelium-specific cell surface receptor that is low/undetectable in healthy adult epithelium but up-regulated in select injured tissues, including...
Sat Sep 19, 2020 00:24
Parametric imaging has been shown to provide better quantitation physiologically compared with SUV imaging in PET. With the increased sensitivity from a recently developed total-body PET scanner, whole-body scans with higher temporal resolution become possible for dynamic analysis and parametric imaging. In this paper, we focus on deriving the parameter k1 using compartmental modeling, and on developing a method to acquire whole-body FDG-PET parametric images using only the first 90 seconds of the...
Sat Sep 19, 2020 00:24
Positron emission tomography (PET) with 18F-fluorodeoxyglucose (18F-FDG) has been increasingly applied, predominantly in the research setting, to study drug effects and pulmonary biology and monitor disease progression and treatment outcomes in lung diseases, disorders that interfere with gas exchange through alterations of the pulmonary parenchyma, airways and/or vasculature. To date, however, there are no widely accepted standard acquisition protocols and imaging data analysis methods for pulmonary...
Sat Sep 19, 2020 00:24
Purpose: Our objective was to evaluate the impact of utility of 18Fluorine (18F)-Fluorodeoxyglucose (FDG) positron emission tomography (PET) computed tomography (CT) in the management of urachal adenocarcinoma (UrC-ADC). Methods: A retrospective analysis of patients with UrC-ADC from 2001-2019 at Memorial Sloan Kettering was performed. Mayo stage prior to 18F-FDG-PET/CT, rates of detection of the primary malignancy and metastases on 18F-FDG PET/CT, Mayo stage after 18F-FDG-PET/CT, and changes...
Sat Sep 19, 2020 00:24
In this study the aromatic nanocolloids (CANCs) are synthesized using the noble metal silver by using Citronella extract and confirmed through physio chemical analysis. The synthesised CANCs were evaluated for...
Fri Sep 18, 2020 03:00
Sable (Martes zibellina), a member of family Mustelidae, order Carnivora, is primarily distributed in the cold northern zone of Eurasia. The purpose of this study was to explore the intestinal flora of the sable ...
Fri Sep 18, 2020 03:00
The giant sequoia (Sequoiadendron giganteum) of California are massive, long-lived trees that grow along the U.S. Sierra Nevada mountains. Genomic data are limited in giant sequoia and producing a reference genome sequence has been an important goal to allow marker development for restoration and management. Using deep-coverage Illumina and Oxford Nanopore sequencing, combined with Dovetail chromosome conformation capture libraries, the genome was assembled into eleven chromosome-scale scaffolds...
Fri Sep 18, 2020 23:25
Tissue Engineering Part A, Volume 26, Issue 17-18, Page 927-927, September 2020.
Thu Sep 17, 2020 10:00
Tissue Engineering Part A, Volume 26, Issue 17-18, Page 931-932, September 2020.
Thu Sep 17, 2020 10:00
Tissue Engineering Part A, Volume 26, Issue 17-18, Page 928-928, September 2020.
Thu Sep 17, 2020 10:00
Tissue Engineering Part A, Volume 26, Issue 17-18, Page 933-934, September 2020.
Thu Sep 17, 2020 10:00
Tissue Engineering Part A, Volume 26, Issue 17-18, Page 929-930, September 2020.
Thu Sep 17, 2020 10:00
Tissue Engineering Part A, Volume 26, Issue 17-18, Page 1024-1024, September 2020.
Thu Sep 17, 2020 10:00
Tissue Engineering Part A, Volume 26, Issue 17-18, Page 935-938, September 2020.
Thu Sep 17, 2020 10:00
Tissue Engineering Part A, Ahead of Print.
Fri Sep 18, 2020 10:00
Tissue Engineering Part A, Ahead of Print.
Fri Sep 18, 2020 10:00
Tissue Engineering Part A, Ahead of Print.
Fri Sep 18, 2020 10:00
Construction and Evaluation of Osteochondral-Like Tissue Using Chondrocyte Sheet and Cancellous Bone
Tissue Engineering Part A, Ahead of Print.
Fri Sep 18, 2020 10:00
Tissue Engineering Part A, Ahead of Print.
Fri Sep 18, 2020 10:00
Thyroid, Ahead of Print.
Fri Sep 18, 2020 10:00
The aim of this study is to evaluate the efficacy of different treatment strategies and the potential prognostic factors of esthesioneuroblastoma (ENB).
Fri Sep 18, 2020 03:00
Abstract Gb3 glycosphingolipids are the specific receptors for bacterial Shiga toxin. Whereas the trisaccharidic head group of Gb3 defines the specificity of Shiga toxin binding, the lipophilic part composed of sphingosine and different fatty acids is suggested to determine its localization within membranes impacting membrane organisation and protein binding eventually leading to protein internalisation. While most studies use Gb3 extracts, chemical synthesis provides a unique...
Sat Sep 19, 2020 03:00
Stem Cells and Development, Ahead of Print.
Fri Sep 18, 2020 10:00
Abstract Heterologously expressed and purified azoreductase enzyme from facultative Klebsiella pneumoniae was used to degrade sulphonated azo dye. Methyl orange (MO) was used as the model dye to study the azo dye decolorization potential of the purified enzyme at different conditions. The enzyme had maximum activity at 40 °C and pH 8.0. The enzyme was observed to be thermo-stable as some enzyme activity was retained even at 80 °C. The apparent kinetic parameters, i.e., appKm and...
Fri Sep 18, 2020 03:00
Abstract Human gut microbiota exists in a complicated symbiotic relationship which postulates to impact health and disease conditions on the host. Interestingly, the gut microbiome shows different mechanisms to regulate host physiology and metabolism including cell-to-cell communications. But microbiota imbalance is characterized to change in the host normal functioning and lead to the development and progression of major human diseases. Therefore, the direct cross talk through...
Sat Sep 19, 2020 03:00
Abstract Purpose of Review Although common, post-traumatic headache (PTH) in the pediatric population is a niche group with a paucity of published evidence on the diagnosis, most appropriate acute and preventative management, and prognosis. This article aims to review pediatric PTH, its epidemiology and pathophysiology with a focus on management and future directions. ...
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Background: As craniofacial fellowship positions outnumber the availability of academic craniofacial jobs, it is important to understand the factors associated with securing an academic position after fellowship. The purpose of this study was to evaluate the impact of bibliometric indices and trainee demographics on the ability to obtain a full-time academic plastic surgery position upon completion of a craniofacial fellowship. Methods: Craniofacial fellowship graduates between 2009-2018...
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