Related Articles Fetal Intrapericardial Teratomas: An Update. Z Geburtshilfe Neonatol. 2020 Aug;224(4):187-193 Authors: Yuan SM Abstract Fetal intrapericardial teratomas are rare and benign cardiac tumors. By comprehensive literature retrieval of the pertinent articles published since 2000, 49 articles with 61 cases of intrapericadial teratomas were recruited into this study. The intrapericardial teratomas were found during pregnancy in 55...
Sun Sep 20, 2020 07:00
Related Articles A case of bullous Sézary syndrome. Dermatol Online J. 2020 Apr 15;26(4): Authors: Wu S, Jenkins F, Byrd R, Googe PB, Jolly PS Abstract Sézary syndrome is a rare leukemic subtype of cutaneous T cell lymphoma that is characterized by erythroderma, lymphadenopathy, and malignant T cells in the peripheral blood. Poor prognostic factors of Sézary syndrome include advanced disease stage, older age at onset, and large cell transformation....
Sun Sep 20, 2020 07:00
Related Articles Towards a novel target therapy for renal diseases related to plasma cell dyscrasias: The example of AL amyloidosis. Autoimmun Rev. 2020 Sep;19(9):102622 Authors: Roccatello D, Fenoglio R, Baldovino S, Naretto C, Ferro M, Barreca A, Rossi D, Sciascia S Abstract Immunoglobulin light chain amyloidosis is a rare systemic disease caused by monoclonal light chains (LCs) depositing in tissue as insoluble fibrils resulting in irreversible...
Sun Sep 20, 2020 07:00
Related Articles A rare variant of African ancestry activates 8q24 lncRNA hub by modulating cancer associated enhancer. Nat Commun. 2020 07 17;11(1):3598 Authors: Walavalkar K, Saravanan B, Singh AK, Jayani RS, Nair A, Farooq U, Islam Z, Soota D, Mann R, Shivaprasad PV, Freedman ML, Sabarinathan R, Haiman CA, Notani D Abstract Genetic variation at the 8q24 locus is linked with the greater susceptibility to prostate cancer in men of African...
Sun Sep 20, 2020 07:00
Related Articles Multimodal Imaging of Nodular Posterior Scleritis: Case Report and Review of the Literature. Middle East Afr J Ophthalmol. 2020 Apr-Jun;27(2):134-138 Authors: Alsarhani WK, Abu El-Asrar AM Abstract Nodular posterior scleritis represents a small percentage of all cases of posterior scleritis. Because of the scarcity of nodular posterior scleritis, it may be confused or even misdiagnosed as an intraocular tumor or posterior uveitis....
Sun Sep 20, 2020 07:00
Related Articles Assessment of In Vitro Anti-melanoma Potential of Ephedranthus pisocarpus R.E.Fr. Anticancer Res. 2020 Sep;40(9):5015-5024 Authors: Santos LKB, Veras MDA, Marques KKG, DE Moraes Alves MM, Mendes AN, DE Amorim Carvalho FA, Sobral MV, Chaves MH, GonÇalves JCR Abstract BACKGROUND/AIM: Despite being a rare disease, melanoma is considered the most dangerous skin cancer due to its highly invasive and aggressive nature, and still...
Sun Sep 20, 2020 07:00
Related Articles Case report: a nonfunctioning juxtaglomerular cell tumor mimicking renal cell carcinoma. Medicine (Baltimore). 2020 Sep 04;99(36):e22057 Authors: Dong J, Xu W, Ji Z Abstract INTRODUCTION: Based on existing literature, the juxtaglomerular cell tumor (JGCT) is a rare renal tumor, typically present with hypertension and hypokalemia. Nonfunctioning JGCT, without hypertension or hypokalemia, is extremely rare. PATIENT CONCERNS:...
Sun Sep 20, 2020 07:00
Related Articles [Diffuse Leptomeningeal Glioneuronal Tumor with Subarachnoid Hemorrhage:A Case Report]. No Shinkei Geka. 2020 Sep;48(9):801-808 Authors: Igarashi K, Kawanami K, Yamaki T, Matsuda KI, Komori T, Sonoda Y Abstract Diffuse leptomeningeal glioneuronal tumor(DLGNT)is a rare primary neoplasm of the central nervous system, and is a condition that is newly listed in the 2016 World Health Organization(WHO)classification of tumors of the...
Sun Sep 20, 2020 07:00
Related Articles [A Case of Erdheim-Chester Disease that was Difficult to Differentiate from Meningioma]. No Shinkei Geka. 2020 Sep;48(9):809-818 Authors: Yoshiyama T, Munakata W, Maeshima A, Umesaki A, Yamaga H, Nishiyama A, Nakajo T, Tanaka Y, Matsumoto H, Terada T Abstract OBJECTIVE: Erdheim-Chester disease(ECD)is a rare type of non-Langerhans histiocytosis. We report a surgical case of ECD with multiple lesions at the falx cerebri, tentorium...
Sun Sep 20, 2020 07:00
Related Articles N-Terminal Acetyltransferases Are Cancer-Essential Genes Prevalently Upregulated in Tumours. Cancers (Basel). 2020 Sep 15;12(9): Authors: Koufaris C, Kirmizis A Abstract N-terminal acetylation (Nt-Ac) is an abundant eukaryotic protein modification, deposited in humans by one of seven N-terminal acetyltransferase (NAT) complexes composed of a catalytic and potentially auxiliary subunits. The involvement of NATs in cancers is...
Sun Sep 20, 2020 07:00
Related Articles Coexistence of Benign Brenner Tumor with Mucinous Cystadenoma in an Ovarian Mass. Iran J Pathol. 2020;15(4):334-337 Authors: Nazari F, Dehghani Z Abstract Ovarian cancer is the most lethal gynecologic malignancy. The surface epithelial tumor is the most common type of ovarian cancer. Among these, the mucinous tumors account for 10-15% of ovarian tumors. Mucinous ovarian tumors are among the most difficult ovarian neoplasms for...
Sun Sep 20, 2020 07:00
Related Articles Pancreatic cystic desmoid tumor following metastatic colon cancer surgery: A case report. Radiol Case Rep. 2020 Nov;15(11):2063-2066 Authors: Shayesteh S, Salimian KJ, Fouladi DF, Blanco A, Chu LC, Fishman EK Abstract Desmoid tumors are rare, benign, and locally aggressive neoplasms that stem from connective tissue that have high rates of recurrence after surgery. Intra-abdominal desmoid-type fibromatosis can arise in 2 forms:...
Sun Sep 20, 2020 07:00
Related Articles Periampullary duodenal schwannoma mimicking ampullary neoplasm. Radiol Case Rep. 2020 Nov;15(11):2085-2089 Authors: Rubio Sierra MP, Alrakawi A, Alduaij A, AlNuaimi D, Balci NC Abstract Schwannomas are neurogenic tumors that arise from Schwann cells in the neural sheath. Gastrointestinal schwannomas occur most often in the stomach, followed by the colon and the rectum. Duodenal schwannomas are rare amongst mesenchymal tumors...
Sun Sep 20, 2020 07:00
Related Articles Systemic autoimmune disease as a cause of death: mortality burden and comorbidities. Rheumatology (Oxford). 2020 Sep 18;: Authors: Mitratza M, Klijs B, Hak AE, Kardaun JWPF, Kunst AE Abstract OBJECTIVES: Systemic autoimmune diseases (SAIDs) have chronic trajectories and share characteristics of self-directed inflammation, as well as aspects of clinical expression. Nonetheless, burden-of-disease studies rarely investigate them...
Sun Sep 20, 2020 07:00
Related Articles Fournier's gangrene - challenge for surgeon. Pol Przegl Chir. 2019 Nov 21;92(5):1-5 Authors: Kuchinka J, Matykiewicz J, Wawrzycka I, Kot M, Karcz W, Głuszek S Abstract INTRODUCTION: Fournier gangrene (FG) is life - threatening condition, defined as the necrotizing fascitis of perineum and can spread to the adjacent areas. It is rare disease and infection is caused by mixed bacterial flora, seldom by fungal infection. Risk factors...
Sun Sep 20, 2020 07:00
Related Articles Polycythemia Vera: Symptom Burden, Oncology Nurse Considerations, and Patient Education. Clin J Oncol Nurs. 2020 Oct 01;24(5):575-578 Authors: Brennan-Cook J Abstract Polycythemia vera (PV) is a rare progressive myelo-proliferative cancer with significant symptom burden. Patients with PV often experience symptoms that adversely affect quality of life, work productivity, and functional status. Oncology nurses are well suited...
Sun Sep 20, 2020 07:00
Related Articles Role of Nrf2 and mitochondria in cancer stem cells; in carcinogenesis, tumor progression, and chemoresistance. Biochimie. 2020 Sep 15;: Authors: Payandeh Z, Tazehkand AP, Barati G, Pouremamali F, Kahroba H, Baradaran B, Samadi N Abstract Cancer stem cells (CSCs) are rare sub-population in tumor mass with self-renewal and differentiation abilities; CSCs are considered as the main cells which are responsible for tumor metastasis,...
Sun Sep 20, 2020 07:00
Related Articles Cancer of the Vulva: A Review. Dermatol Surg. 2020 Sep 15;: Authors: Michalski BM, Pfeifer JD, Mutch D, Council ML Abstract BACKGROUND: Vulvar cancers, although rare, are becoming an increasingly serious threat to women's health. Cancer of the vulva accounted for 0.3% of all new cancers in the United States in 2019, with 6,070 newly diagnosed cases. This review details the epidemiology, pathogenesis, diagnosis, staging, and...
Sun Sep 20, 2020 07:00
Related Articles A Case of Synchronous Malignant and Benign Granular Cell Tumor of the Vulva. Int J Gynecol Pathol. 2020 Sep 17;: Authors: Baranova K, Goebel EA, McGee J, Walsh JC Abstract Granular cell tumors (GCT) are rare soft tissue neoplasms, which seldom occur in the vulva. They are more commonly benign, but malignant GCT do occur. We report a case of a 50-yr-old postmenopausal woman who presented with a vulvar lesion that was diagnosed...
Sun Sep 20, 2020 07:00
Related Articles Surgical Management of Neuroendocrine Tumours of the Pancreas. J Clin Med. 2020 Sep 16;9(9): Authors: Souche R, Hobeika C, Hain E, Gaujoux S Abstract Neuroendocrine tumours of the pancreas (pNET) are rare, accounting for 1-2% of all pancreatic neoplasms. They develop from pancreatic islet cells and cover a wide range of heterogeneous neoplasms. While most pNETs are sporadic, some are associated with genetic syndromes. Furthermore,...
Sun Sep 20, 2020 13:07
Related Articles Multiple paragangliomas: a case report. BMC Med Genomics. 2020 Sep 18;13(Suppl 8):125 Authors: Pavlov VS, Kalinin DV, Lukyanova EN, Golovyuk AL, Fedorova MS, Pudova EA, Savvateeva MV, Lipatova AV, Guvatova ZG, Kaprin AD, Kiseleva MV, Demidova TB, Simanovsky SA, Melnikova NV, Dmitriev AA, Krasnov GS, Snezhkina AV, Kudryavtseva AV Abstract BACKGROUND: Carotid and vagal paragangliomas (CPGLs and VPGLs) are rare neoplasms that arise...
Sun Sep 20, 2020 13:07
Related Articles The Landmark Series: Pancreatic Neuroendocrine Tumors. Ann Surg Oncol. 2020 Sep 18;: Authors: Cloyd JM, Poultsides GA Abstract Pancreatic neuroendocrine tumors (PNETs) comprise a heterogeneous group of neoplasms arising from pancreatic islet cells that remain relatively rare but are increasing in incidence worldwide. While significant advances have been made in recent years with regard to systemic therapies for patients with...
Sun Sep 20, 2020 13:07
Related Articles Pregnancy in Women with Metastatic Sarcomas. Oncologist. 2020 Sep 19;: Authors: Yazigi A, Lecointe-Artzner E, Cesne AL, Ray-Coquard I, Blay JY Abstract Successful pregnancy in women with metastatic cancer is rare in the published literature. We report here on four women with sarcoma who started and conducted their first pregnancies while in metastatic disease. All four pregnancies were first pregnancies, and all four women are...
Sun Sep 20, 2020 13:07
Related Articles Single-Cell Sequencing in Human Genital Infections. Adv Exp Med Biol. 2020;1255:203-220 Authors: Singh R Abstract Human genital infections are one of the most concerning issues worldwide and can be categorized into sexually transmitted, urinary tract and vaginal infections. These infections, if left untreated, can disseminate to the other parts of the body and cause more complicated illnesses such as pelvic inflammatory disease,...
Sun Sep 20, 2020 13:07
Related Articles Gene therapy in solid tumors: trends in trials in China and beyond. Drug Discov Today. 2020 Sep 16;: Authors: Chen K, Wang S, Chen B, Sun F, Li N Abstract Gene therapy involves the introduction of new genes into cells, to modify or manipulate the expression of a gene or to alter the biological properties, for the purpose of treating disease. It is designed to treat genetic diseases at their root, by correcting the mutation responsible,...
Sun Sep 20, 2020 15:07
Related Articles Non-coding RNA in thyroid cancer - Functions and mechanisms. Cancer Lett. 2020 Sep 16;: Authors: Cao J, Zhang M, Zhang L, Lou J, Zhou F, Fang M Abstract Thyroid cancer is the most common endocrine malignant tumor, and its incidence has increased significantly in the past few years. A growing number of noncoding RNAs (ncRNAs) have shown abnormal expression patterns in human thyroid cancer in recent studies. Depending on size,...
Sun Sep 20, 2020 15:07
ProtyQuant: Comparing label-free shotgun proteomics datasets using accumulated peptide probabilities
Publication date: Available online 19 September 2020Source: Journal of ProteomicsAuthor(s): Robert Winkler
Sat Sep 19, 2020 23:20
Publication date: Available online 19 September 2020Source: Journal of ProteomicsAuthor(s): Weiyi Li, Yifan Yin, Yu Meng, Hong Zhou, Zhe Ma, Huixing Lin, Hongjie Fan
Sun Sep 20, 2020 13:14
Publication date: Available online 20 September 2020Source: Journal of ProteomicsAuthor(s): Ilaria Iacobucci, Vittoria Monaco, Flora Cozzolino, Maria Monti
Sun Sep 20, 2020 13:14
32 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/09/18PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Sep 18, 2020 13:35
35 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/09/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Sep 20, 2020 07:13
Related Articles The future of cell-free DNA testing to guide therapeutic decisions in B-cell lymphomas. Curr Opin Hematol. 2019 07;26(4):281-287 Authors: Condoluci A, Rossi D Abstract PURPOSE OF REVIEW: Tissue biopsy is the current gold standard technique for diagnosis and molecular profiling of lymphomas, but it carries several disadvantages in terms of procedural risks (infectious and haemorrhagic complications, anaesthesiologic risks) and...
Sun Sep 20, 2020 13:15
Related Articles Bromodomain and Extra-Terminal domain inhibitors for lymphoid malignancies. Curr Opin Hematol. 2019 07;26(4):273-280 Authors: Bertoni F, Stathis A Abstract PURPOSE OF REVIEW: Pharmacological inhibition of Bromodomain and Extra-Terminal (BET) domain proteins is a very exciting epigenetic therapeutic modality. Due to the central role of BET proteins in transcription regulation, their inhibition heavily affects lymphoma cells...
Sun Sep 20, 2020 13:15
Related Articles Antibody Responses to Fusobacterium nucleatum Proteins in Prediagnostic Blood Samples are not Associated with Risk of Developing Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2019 09;28(9):1552-1555 Authors: Butt J, Jenab M, Pawlita M, Overvad K, Tjonneland A, Olsen A, Boutron-Ruault MC, Carbonnel F, Mancini FR, Kaaks R, Kühn T, Boeing H, Trichopoulou A, Karakatsani A, Palli D, Pala VM, Tumino R, Sacerdote C, Panico S, Bueno-de-Mesquita...
Sun Sep 20, 2020 13:15
Related Articles Bioinformatics Data Mining Repurposes the JAK2 (Janus Kinase 2) Inhibitor Fedratinib for Treating Pancreatic Ductal Adenocarcinoma by Reversing the KRAS (Kirsten Rat Sarcoma 2 Viral Oncogene Homolog)-Driven Gene Signature. J Pers Med. 2020 Sep 16;10(3): Authors: Liu LW, Hsieh YY, Yang PM Abstract Pancreatic ductal adenocarcinoma (PDAC) is still one of the most aggressive and lethal cancer types due to the late diagnosis,...
Sun Sep 20, 2020 13:15
Related Articles Liquid lncRNA Biopsy for the Evaluation of Locally Advanced and Metastatic Squamous Cell Carcinomas of the Head and Neck. J Pers Med. 2020 Sep 16;10(3): Authors: Łasińska I, Kolenda T, Guglas K, Kopczyńska M, Sobocińska J, Teresiak A, Strzelecki NO, Lamperska K, Mackiewicz A, Mackiewicz J Abstract Background: Long non-coding RNA (lncRNA) are RNA molecules that are more than 200 nucleotides long and have the ability to modify...
Sun Sep 20, 2020 13:15
Related Articles Expression profile of SYNE3 and bioinformatic analysis of its prognostic value and functions in tumors. J Transl Med. 2020 Sep 18;18(1):355 Authors: Liao L, Zhang L, Yang M, Wang X, Huang W, Wu X, Pan H, Yuan L, Huang W, Wu Y, Guan J Abstract BACKGROUND: Spectrin repeat containing nuclear envelope family member 3 (SYNE3) encodes an essential component of the linker of the cytoskeleton and nucleoskeleton (LINC) complex,...
Sun Sep 20, 2020 13:15
Related Articles Assessment of the quality of recommendations from 161 clinical practice guidelines using the Appraisal of Guidelines for Research and Evaluation-Recommendations Excellence (AGREE-REX) instrument shows there is room for improvement. Implement Sci. 2020 Sep 18;15(1):79 Authors: Florez ID, Brouwers MC, Kerkvliet K, Spithoff K, Alonso-Coello P, Burgers J, Cluzeau F, Férvers B, Graham I, Grimshaw J, Hanna S, Kastner M, Kho M, Qaseem A, Straus S...
Sun Sep 20, 2020 13:15
Related Articles Brachytherapy in India: Learning from the past and looking into the future. Brachytherapy. 2020 Sep 15;: Authors: Kumar A, Chopra S, Mahantshetty U, Reddy VA Abstract India has a longstanding tradition in the practice of brachytherapy and has actively contributed to the scientific literature by conducting prospective studies, clinical audits, developing innovative techniques, and performing randomized studies. Indian investigators...
Sun Sep 20, 2020 13:15
Related Articles Comprehensive Cervical Cancer Prevention in Tanzania (CONCEPT) study: Cohort profile. BMJ Open. 2020 Sep 18;10(9):e038531 Authors: Mchome B, Swai P, Wu C, Katanga J, Kahesa C, Manongi R, Mwaiselage JD, Kjaer S, Rasch V, Linde DS Abstract PURPOSE: Cervical cancer is a major cause of death among women in Eastern Africa, and the distribution of human papillomavirus (HPV) according to HIV status is inadequately characterised...
Sun Sep 20, 2020 13:15
Related Articles Response to neoadjuvant treatment among rectal cancer patients in a population-based cohort. Int J Colorectal Dis. 2020 Sep 19;: Authors: Alwers E, Jansen L, Kather J, Amitay E, Bläker H, Kloor M, Tagscherer KE, Roth W, Herpel E, Chang-Claude J, Brenner H, Hoffmeister M Abstract BACKGROUND: In rectal cancer, prediction of tumor response and pathological complete response (pCR) to neoadjuvant treatment could contribute to...
Sun Sep 20, 2020 13:15
Related Articles Abdominal and pelvic 18F-FDG PET/MR: a review of current and emerging oncologic applications. Abdom Radiol (NY). 2020 Sep 19;: Authors: Ward RD, Amorim B, Li W, King J, Umutlu L, Groshar D, Harisinghani M, Catalano O Abstract Positron emission tomography (PET) using fluorodeoxyglucose (18F-FDG) combined with magnetic resonance imaging (MR) is an emerging hybrid modality that has shown utility in evaluating abdominal and...
Sun Sep 20, 2020 13:15
Related Articles Immune evasion in renal cell carcinoma: biology, clinical translation, future directions. Kidney Int. 2020 Sep 16;: Authors: Wang X, Lopez R, Luchtel RA, Hafizi S, Gartrell B, Shenoy N Abstract Targeted therapies and immune checkpoint inhibitors have advanced the treatment landscape of Renal Cell Carcinoma (RCC) over the last decade. While checkpoint inhibitors have demonstrated survival benefit and are currently approved...
Sun Sep 20, 2020 15:15
Related Articles Development of a Stakeholder Driven Serious Illness Communication Program for Advance Care Planning in Children, Adolescents, and Young Adults with Serious Illness. J Pediatr. 2020 Sep 16;: Authors: DeCourcey DD, Partin L, Revette A, Bernacki R, Wolfe J Abstract OBJECTIVES: To develop a generalizable advance care planning ACP intervention for children and children, adolescents, and young adults with serious illness using...
Sun Sep 20, 2020 15:15
Related Articles Malignant peripheral nerve sheath tumors - Outcomes and prognostic factors based on the reference center experience. Surg Oncol. 2020 Sep 12;35:276-284 Authors: Sobczuk P, Teterycz P, Czarnecka AM, Świtaj T, Koseła-Paterczyk H, Kozak K, Falkowski S, Goryń T, Zdzienicki M, Morysiński T, Rutkowski P Abstract INTRODUCTION: Malignant peripheral nerve sheath tumor (MPNST) accounts for about 5% of soft tissue sarcomas. It can...
Sun Sep 20, 2020 15:15
Related Articles Impact of hearing loss and vestibular decline on cognition in Alzheimer's disease: a prospective longitudinal study protocol (Gehoor, Evenwicht en Cognitie, GECkO). BMJ Open. 2020 Sep 17;10(9):e039601 Authors: Bosmans J, Jorissen C, Cras P, Van Ombergen A, Engelborghs S, Gilles A, Princen E, Moyaert J, Mertens G, Van Rompaey V Abstract INTRODUCTION: Dementia is a prevalent disease affecting a growing number of the ageing population....
Sun Sep 20, 2020 13:16
186 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: head and neck These pubmed results were generated on 2020/09/18PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Sep 18, 2020 14:19
Related Articles Voice Onset Time in Individuals With Hyperfunctional Voice Disorders: Evidence for Disordered Vocal Motor Control. J Speech Lang Hear Res. 2020 02 26;63(2):405-420 Authors: McKenna VS, Hylkema JA, Tardif MC, Stepp CE Abstract Purpose This study examined vocal hyperfunction (VH) using voice onset time (VOT). We hypothesized that speakers with VH would produce shorter VOTs, indicating increased laryngeal tension, and more variable...
Sun Sep 20, 2020 06:28
Related Articles Clinical Results of Fibroblast Activation Protein (FAP) Specific PET and Implications for Radiotherapy Planning: Systematic Review. Cancers (Basel). 2020 Sep 15;12(9): Authors: Windisch P, Zwahlen DR, Koerber SA, Giesel FL, Debus J, Haberkorn U, Adeberg S Abstract Small molecules targeting fibroblast activation protein (FAP) have emerged as a new group of tracers for positron emission tomography (PET) in 2018. The purpose...
Sun Sep 20, 2020 06:28
Related Articles Traditional Herbal Medicine Mediated Regulations during Head and Neck Carcinogenesis. Biomolecules. 2020 Sep 15;10(9): Authors: Lan XY, Chung TT, Huang CL, Lee YJ, Li WC Abstract Head and neck squamous cell carcinoma (HNSCC) is one of the most prevalent neoplasms worldwide. It is well recognized that environmental challenges such as smoking, viral infection and alcohol consumption are key factors underlying HNSCC pathogenesis....
Sun Sep 20, 2020 06:28
Related Articles HNSCC: Tumour Antigens and Their Targeting by Immunotherapy. Cells. 2020 Sep 15;9(9): Authors: von Witzleben A, Wang C, Laban S, Savelyeva N, Ottensmeier CH Abstract Head and neck squamous cell carcinomas (HNSCC) are a heterogeneous group of malignant tumours typically caused by alcohol and tobacco consumption, although an increasing number of HNSCC arise due to persistent infection with high-risk human papilloma virus...
Sun Sep 20, 2020 06:28
Related Articles Gene expression within the periaqueductal gray is linked to vocal behavior and early-onset parkinsonism in Pink1 knockout rats. BMC Genomics. 2020 Sep 17;21(1):625 Authors: Kelm-Nelson CA, Gammie S Abstract BACKGROUND: Parkinson's disease (PD) is a degenerative disease with early-stage pathology hypothesized to manifest in brainstem regions. Vocal deficits, including soft, monotone speech, result in significant clinical...
Sun Sep 20, 2020 06:28
Related Articles Antimicrobial prophylaxis is considered sufficient to preserve an acceptable surgical site infection rate in clean orthopaedic and neurosurgeries in dogs. Acta Vet Scand. 2020 Sep 17;62(1):53 Authors: Välkki KJ, Thomson KH, Grönthal TSC, Junnila JJT, Rantala MHJ, Laitinen-Vapaavuori OM, Mölsä SH Abstract BACKGROUND: Surgical site infections (SSI) are associated with increased morbidity and mortality. To lower the incidence...
Sun Sep 20, 2020 06:28
Related Articles Robotic Neck Dissection. Otolaryngol Clin North Am. 2020 Sep 14;: Authors: Godse NR, Zhu TS, Duvvuri U Abstract Management of head and neck squamous cell carcinoma necessitates a multimodal approach. The neck dissection has evolved over many years but is well established as the key surgical intervention for management of nodal disease in the neck. The open neck dissection has many varieties based on location and degree...
Sun Sep 20, 2020 06:28
Related Articles Complaints of neuropathic pain, noxious cervical plexus neuropathy and neck tightness are reported by patients who undergo neck dissection: an institutional study and narrative review. Br J Oral Maxillofac Surg. 2020 Aug 19;: Authors: Ramphul A, Hoffman GR, Islam S, McGarvey AC, Powell AD Abstract There exists a subgroup of patients who undergo neck dissection (ND) who postoperatively complain of either neuropathic pain,...
Sun Sep 20, 2020 06:28
Related Articles Multiparametric magnetic resonance imaging of parotid tumors: A systematic review. Diagn Interv Imaging. 2020 Sep 14;: Authors: Coudert H, Mirafzal S, Dissard A, Boyer L, Montoriol PF Abstract PURPOSE: The purpose of this systematic review was to provide an overview of the contribution of multiparametric magnetic resonance imaging (MRI) in the diagnosis of parotid tumors (PT) and recommendations based on current evidences....
Sun Sep 20, 2020 06:28
Related Articles Prediction of Human Papillomavirus Status and Overall Survival in Patients with Untreated Oropharyngeal Squamous Cell Carcinoma: Development and Validation of CT-Based Radiomics. AJNR Am J Neuroradiol. 2020 Sep 17;: Authors: Choi Y, Nam Y, Jang J, Shin NY, Ahn KJ, Kim BS, Lee YS, Kim MS Abstract BACKGROUND AND PURPOSE: Human papillomavirus is a prognostic marker for oropharyngeal squamous cell carcinoma. We aimed to determine...
Sun Sep 20, 2020 06:28
Related Articles Percutaneous CT-Guided Core Needle Biopsies of Head and Neck Masses: Technique, Histopathologic Yield, and Safety at a Single Academic Institution. AJNR Am J Neuroradiol. 2020 Sep 17;: Authors: Hillen TJ, Baker JC, Long JR, Friedman MV, Jennings JW Abstract BACKGROUND AND PURPOSE: CT-guided head and neck biopsies can be challenging due to the anatomy and adjacent critical structures but can often obviate the need for open...
Sun Sep 20, 2020 06:28
Related Articles Case of anti-Zic4 antibody-mediated cerebellar toxicity induced by dual checkpoint inhibition in head and neck squamous cell carcinoma. BMJ Case Rep. 2020 Sep 17;13(9): Authors: Iyer SG, Khakoo NS, Aitcheson G, Perez C Abstract Combined checkpoint inhibition therapy targeting the programmed cell death 1 (PD-L1) and cytotoxic T-lymphocyte associated protein 4 pathways has been a successful approach in the treatment of metastatic...
Sun Sep 20, 2020 06:28
Related Articles Unilateral nasal obstruction on a background of sarcoidosis: an unusual diagnosis. BMJ Case Rep. 2020 Sep 17;13(9): Authors: Campbell E, McLaren O PMID: 32943449 [PubMed - in process]
Sun Sep 20, 2020 06:28
Related Articles Phase 1B Study of Chemoprevention with Green Tea Polyphenon E and Erlotinib in Patients with Advanced Premalignant Lesions (APL) of the Head and Neck. Clin Cancer Res. 2020 Sep 17;: Authors: Shin DM, Nannapaneni S, Patel MR, Shi Q, Liu Y, Chen Z, Chen A, El-Deiry MW, Beitler JJ, Steuer CE, Roser SM, Klein AM, Owonikoko TK, Ramalingam SS, Khuri FR, Chen ZG, Saba NF Abstract PURPOSE: Based on synergistic effects between green...
Sun Sep 20, 2020 06:28
Related Articles The Efficacy of Low Postoperative Radiation Dose in Patients with Advanced Hypopharyngeal Cancer without High-Risk Factors. Cancer Manag Res. 2020;12:7553-7560 Authors: Tao H, Shen Z, Liu Z, Wei Y Abstract Objective: To evaluate the feasibility and efficacy of low postoperative radiotherapy (PORT) dose in patients with advanced hypopharyngeal squamous cell carcinoma (HPSCC) and identify prognostic factors in this group....
Sun Sep 20, 2020 06:28
Related Articles Modulation of pathogenic oral biofilms towards health with nisin probiotic. J Oral Microbiol. 2020 Aug 24;12(1):1809302 Authors: Radaic A, Ye C, Parks B, Gao L, Kuraji R, Malone E, Kamarajan P, Zhan L, Kapila YL Abstract Background: Oral dysbiosis is an imbalance in the oral microbiome and is associated with a variety of oral and systemic diseases, including periodontal disease, caries, and head and neck/oral cancer. Although...
Sun Sep 20, 2020 06:28
Related Articles miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas. J Extracell Vesicles. 2020 Jul 13;9(1):1790159 Authors: Flemming JP, Hill BL, Haque MW, Raad J, Bonder CS, Harshyne LA, Rodeck U, Luginbuhl A, Wahl JK, Tsai KY, Wermuth PJ, Overmiller AM, Mahoney MG Abstract Exosomes, or small extracellular vesicles (sEVs), serve as intercellular messengers with key roles in normal and pathological processes....
Sun Sep 20, 2020 06:28
Related Articles Determining the molecular landscape and impact on prognosis in HPV-associated head and neck cancer. Cancers Head Neck. 2020;5:11 Authors: Khanna S, Palackdharry S, Roof L, Wicker CA, Mark J, Zhu Z, Jandorav R, Molinolo A, Takiar V, Wise-Draper TM Abstract Background: Human papillomavirus (HPV) associated head and neck squamous cell carcinoma (HNSCC) has a better prognosis than HNSCC due to other risk factors. However, there...
Sun Sep 20, 2020 06:28
Related Articles Active surveillance as a management strategy for papillary thyroid microcarcinoma. Cancer Biol Med. 2020 Aug 15;17(3):543-554 Authors: Zhang H, Zheng X, Liu J, Gao M, Qian B Abstract Active surveillance (AS) can be considered as a treatment strategy for low risk papillary thyroid microcarcinoma (PTMC), with the absence of clinically apparent lymph nodes, extrathyroidal extensions, and distant metastasis. After reviewing...
Sun Sep 20, 2020 06:28
Related Articles Augmentation Rhinoplasty Using Iliac Crest Graft in Saddle Nose Deformity. Cureus. 2020 Aug 12;12(8):e9705 Authors: Alshehri WM, Aldosari A, Alherz AH, Alrashood OA, Al Qahtani B Abstract Autologous bone graft is one of the management solutions for saddle nose deformity. This helps from both functional and esthetic perspective. Several features of autologous graft specify the best material used to repair bony and cartilaginous...
Sun Sep 20, 2020 06:28
Related Articles Neural reprogramming via microRNAs: the new kid on the p53-deficient block. Mol Cell Oncol. 2020;7(4):1756723 Authors: Silverman DA, Calin GA, Myers JN, Amit M Abstract We recently reported a novel role for nerve-cancer crosstalk, demonstrating that tumor protein p53 (TP53) deficiency in head and neck squamous cell carcinoma leads to a decrease in miR-34a in tumor-shed vesicles. This directed sensory nerve reprogramming...
Sun Sep 20, 2020 06:28
Related Articles In vivo CRISPR screens reveal potent driver mutations in head and neck cancers. Mol Cell Oncol. 2020;7(4):1758541 Authors: Loganathan SK, Schramek D Abstract We have recently tested the transforming potential of 484 'long-tail' genes, which are recurrently albeit infrequently mutated in head and neck cancers (HNSCC). We identified 15 novel tumor suppressors and our top hits converge on regulating the NOTCH signaling pathway....
Sun Sep 20, 2020 06:28
Related Articles Dual-site rTMS is More Effective than Single-site rTMS in Tinnitus Patients: A Blinded Randomized Controlled Trial. Brain Topogr. 2020 Sep 17;: Authors: Noh TS, Kyong JS, Park MK, Lee JH, Oh SH, Suh MW Abstract Repetitive transcranial magnetic stimulation (rTMS) has been proposed as an alternative option for treating tinnitus. rTMS is a noninvasive method in which repetitive magnetic stimulation is applied to the cortex;...
Sun Sep 20, 2020 06:28
Related Articles Perception of male otolaryngologists on gender discrimination: a comparative study. Eur Arch Otorhinolaryngol. 2020 Sep 17;: Authors: Haberal Can İ, İncesulu A, Eyigör H, Şenol Y, Kara CO Abstract PURPOSE: To gather information on perception of male otolaryngologists (MORLs) about gender discrimination towards female otolaryngologists (FORLs). METHODS: MORLs were invited to participate to an online survey. Minimum...
Sun Sep 20, 2020 06:28
Related Articles Is ossicular chain fixation predictable for tympanosclerosis on preoperative temporal bone computed tomography? Eur Arch Otorhinolaryngol. 2020 Sep 18;: Authors: Yildiz S, Balık AÖ, Zer Toros S Abstract PURPOSE: To report the predictability of ossicular chain (OC) fixation on preoperative temporal bone computed tomography (TBCT) in chronic otitis media (COM) with tympanosclerosis (TS). METHODS: Fifty-six patients...
Sun Sep 20, 2020 06:28
Related Articles Diagnostic value of exosomal circMYC in radioresistant nasopharyngeal carcinoma. Head Neck. 2020 Sep 18;: Authors: Luo Y, Ma J, Liu F, Guo J, Gui R Abstract BACKGROUND: The relationship between circulating exosomal circular RNA (circRNA) and prognosis of patients with nasopharyngeal carcinoma (NPC) remain unknown. This study focused on the expression of exosomal circMYC and its relationship with the recurrence and prognosis...
Sun Sep 20, 2020 06:28
Related Articles Effects of baohuoside-I on epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma. Hum Exp Toxicol. 2020 Sep 18;:960327120960765 Authors: Wang Q, Jiang S, Wang W, Jiang H Abstract To investigate the effect of baohuoside-I against nasopharyngeal carcinoma (NPC) and its underlying mechanism, baohuoside-I was employed to treat NPC cell lines CNE1 and CNE2 in vitro, followed by attachment and detachment...
Sun Sep 20, 2020 06:28
Related Articles Extranodal Lymphomas: a pictorial review for CT and MRI classification. Acta Biomed. 2020 Jul 13;91(8-S):34-42 Authors: Reginelli A, Urraro F, Sangiovanni A, Russo GM, Russo C, Grassi R, Agostini A, Belfiore MP, Cellina M, Floridi C, Giovagnoni A, Sica A, Cappabianca S Abstract Extranodal lymphomas represent an extranodal location of both non-Hodgkin and Hodgkin lymphomas. This study aims to evaluate the role of CT and...
Sun Sep 20, 2020 06:28
Related Articles Artesunate inhibits lung cancer cells via regulation of mitochondrial membrane potential and induction of apoptosis. Mol Med Rep. 2020 Jul 15;: Authors: Zhao Y, Liu J, Liu L Abstract Lung cancer is a common malignant disease with a high incidence rate worldwide, posing a great threat to human health. To date, only a small number of studies have assessed the potential anti‑cancer effect of artesunate (Art) and the associated...
Sun Sep 20, 2020 06:28
Related Articles Sensitivity of human papillomavirus‑positive and ‑negative oropharyngeal cancer cell lines to ionizing irradiation. Oncol Rep. 2020 Jul 31;: Authors: Holzhauser S, Pirotte E, Jones J, Owens D, Al-Hussaini A, Giles P, Evans M, Man S, Powell N Abstract Human papillomavirus‑positive (HPV+) oropharyngeal squamous cell carcinoma (OPSCC) has increased in incidence and has a much better prognosis than HPV‑negative (HPV‑) OPSCC...
Sun Sep 20, 2020 06:28
Related Articles The expression and clinical significance of an Epithelial-Mesenchymal Transition inducer, SNAI1, in head and neck carcinoma. J Oral Pathol Med. 2020 Sep 18;: Authors: Zhao H, Ling J, Huang Y, Chang A, Zhuo X Abstract BACKGROUND: SNAI1 is an Epithelial-Mesenchymal Transition (EMT) inducer, which has been indicated to play a role in the progression of cancers. We aimed to evaluate the expression and prognostic roles of SNAI1...
Sun Sep 20, 2020 06:28
Related Articles Changes in treatment trends in the early glottic cancer population after the Affordable Care Act. Head Neck. 2020 Sep 18;: Authors: Panuganti BA, Stuart E, Weissbrod P Abstract BACKGROUND: The clinical impact of Medicaid expansion in otolaryngology is uncertain. Herein, we evaluate the impact of Medicaid expansion on treatment patterns (primary radiotherapy vs surgery) in the early glottic cancer population. METHODS:...
Sun Sep 20, 2020 06:28
Related Articles Transformative Times: Our Journal as We Build and Expand. Facial Plast Surg Aesthet Med. 2020 Sep/Oct;22(5):317-318 Authors: Tollefson TT PMID: 32945716 [PubMed - as supplied by publisher]
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Related Articles Lymphedema: Clinical Summary of the ONS Guidelines™ for Cancer Treatment-Related Lymphedema. Clin J Oncol Nurs. 2020 Oct 01;24(5):566-570 Authors: Backler C, Beck M, Poage E Abstract Secondary (acquired) lymphedema is a chronic condition lacking a known cure that most commonly results from cancer treatment, particularly for breast, gynecologic, prostate, and head and neck cancers; lymphoma; and melanoma, and affects an...
Sun Sep 20, 2020 06:28
Related Articles Comprehensive Geriatric Assessment: A Case Report on Personalizing Cancer Care of an Older Adult Patient With Head and Neck Cancer. Clin J Oncol Nurs. 2020 Oct 01;24(5):514-525 Authors: Strohschein FJ, Loucks A, Jin R, Vanderbyl B Abstract BACKGROUND: Understanding multidimensional screening and assessment is key to optimizing cancer care in older adults. OBJECTIVES: This article aims to present comprehensive...
Sun Sep 20, 2020 06:28
Related Articles Association of serum vitamin D with Chronic RhinoSinusitis in adults residing at high altitudes. Eur Arch Otorhinolaryngol. 2020 Sep 18;: Authors: Thakur P, Potluri P Abstract PURPOSE: To evaluate the association of serum vitamin D levels with chronic rhinosinusitis (CRS) in population residing at high altitudes and to assess its correlation with severity of CRS. METHODS: A prospective case-control study comparing...
Sun Sep 20, 2020 06:28
Related Articles How Should We Approach Locally Advanced Squamous Cell Carcinoma of Head and Neck Cancer Patients Ineligible for Standard Non-surgical Treatment? Curr Oncol Rep. 2020 Sep 18;22(12):118 Authors: Yokota T, Hamauchi S, Shirasu H, Onozawa Y, Ogawa H, Onoe T, Onitsuka T Abstract PURPOSE OF REVIEW: Cisplatin has been established as one of the most important agents in multidisciplinary treatment for head and neck cancer (HNC)....
Sun Sep 20, 2020 06:28
Related Articles Hybrid positron emission tomography imaging for initial staging of sinonasal tumors: Total lesion glycolysis as prognosticator of treatment response. Head Neck. 2020 Sep 18;: Authors: Meerwein CM, Maurer A, Stolzmann P, Stadler TM, Soyka MB, Holzmann D, Hüllner MW Abstract BACKGROUND: To assess hybrid positron emission tomography (PET) imaging in the initial staging and outcome prediction of sinonasal malignancies. ...
Sun Sep 20, 2020 06:28
Related Articles Experiences With and Lessons Learned From Developing, Implementing, and Evaluating a Support Program for Older Hearing Aid Users and Their Communication Partners in the Hearing Aid Dispensing Setting. Am J Audiol. 2020 Sep 18;29(3S):638-647 Authors: Meijerink JFJ, Pronk M, Kramer SE Abstract Purpose The SUpport PRogram (SUPR) study was carried out in the context of a private academic partnership and is the first study to...
Sun Sep 20, 2020 06:28
Related Articles The Development of an Internet-Based Decision Coaching Guide to Encourage Audiology Care: The Results of a Participatory Design Approach. Am J Audiol. 2020 Sep 18;29(3S):546-563 Authors: Burden RS, Galloway LN, Rothpletz AM, Glasheen KA, Preminger JE Abstract Purpose The purpose of the research described here is to create a theoretically based, interactive online program to motivate adults with untreated hearing loss to...
Sun Sep 20, 2020 06:28
Related Articles Rationale, Theoretical Underpinnings, and Design of HEAR-aware: Providing Adults With Hearing Loss With Tailored Support to Self-Manage Their Hearing Problems via a Smartphone App, as an Alternative to Hearing Aids. Am J Audiol. 2020 Sep 18;29(3S):648-660 Authors: Pronk M, Besser J, Smits C, Feenstra-Kikken V, van Beek H, Polleunis C, Kramer SE Abstract Purpose An alarming two thirds of adults aged 50 years or over with...
Sun Sep 20, 2020 06:28
Related Articles Clinical Implication of Diagnostic and Histopathologic Discrepancies in Sinonasal Malignancies. Laryngoscope. 2020 Sep 18;: Authors: Choi KY, Amit M, Tam S, Bell D, Phan J, Garden AS, Williams MD, Ferrarotto R, El-Naggar AK, Raza SM, DeMonte F, Kupferman ME, Hanna EY, Su SY Abstract OBJECTIVES: To evaluate the incidence of histopathologic diagnostic discrepancy for patients referred to our institution, identify pathologies...
Sun Sep 20, 2020 06:28
Related Articles Supraglottic Carcinoma in Intravenous Opioid Drug Abusers: A Distinct Disease with Improved Survival. Laryngoscope. 2020 Sep 18;: Authors: Yaniv D, Reuven Y, Lahav Y, Cohen O, Hamzany Y, Moore A, Rapana OG, Argaman N, Halperin D, Popovtzer A, Bachar G, Shoffel-Havakuk H Abstract OBJECTIVES/HYPOTHESIS: Recent evidence indicates an increased prevalence of intravenous opioid drug abusers (IVDAs) among supraglottic squamous...
Sun Sep 20, 2020 06:28
Related Articles Mandibular Advancement Device Treatment Efficacy is Associated with Polysomnographic Endotypes. Ann Am Thorac Soc. 2020 Sep 18;: Authors: Op de Beeck S, Dieltjens M, Azarbarzin A, Willemen M, Verbraecken J, Braem MJ, Wellman A, Sands SA, Vanderveken OM Abstract RATIONALE: Mandibular advancement device (MAD) treatment efficacy varies among obstructive sleep apnea (OSA) patients. OBJECTIVES: The current study aims...
Sun Sep 20, 2020 06:28
Related Articles Upregulation of miR-155 regulates group 2 innate lymphoid cells by targeting c-maf in allergic rhinitis. Eur J Pharmacol. 2020 Sep 15;:173564 Authors: Zhu Y, Liu Y, Zhu X, Wang Z, Wang M Abstract Group 2 innate lymphoid cells (ILC2s) and Th2 type immune response are critically involved in the pathogenesis of allergic rhinitis (AR), and this pathological process is influenced by microRNAs-mediated post-transcriptional regulation....
Sun Sep 20, 2020 06:28
Related Articles The E2 ubiquitin-conjugating enzyme UbcH5c: an emerging target in cancer and immune disorders. Drug Discov Today. 2020 Sep 16;: Authors: Zhou Y, Chen R, Luo X, Zhang WD, Qin JJ Abstract Ubiquitination is a crucial post-translational modification (PTM) of proteins and regulates their stabilities and activities, thereby modulating multiple signaling pathways. UbcH5c, a member of the UbcH5 ubiquitin-conjugating enzyme (E2)...
Sun Sep 20, 2020 06:28
Related Articles Considerations for environmentally sustainable head and neck surgical oncology practice. Am J Otolaryngol. 2020 Sep 12;41(6):102719 Authors: Sanabria A, Kowalski LP, Nixon IJ, Shaha A, De Bree R, Mäkitie AA, Rinaldo A, Ferlito A Abstract OBJECTIVE: To evaluate the potential role of head and neck oncologic surgeons in environmental protection, sustainability of health-care systems and avoidance of procedures contributing...
Sun Sep 20, 2020 06:28
Related Articles Biological role of epithelial-mesenchymal-transition-inducing transcription factors in head and neck squamous cell carcinoma: A systematic review. Arch Oral Biol. 2020 Sep 10;119:104904 Authors: de Morais EF, Rolim LSA, de Melo Fernandes Almeida DR, de Farias Morais HG, de Souza LB, de Almeida Freitas R Abstract OBJECTIVE: The aim of this systematic review was to explore the biological functions and mechanisms of epithelial-mesenchymal...
Sun Sep 20, 2020 06:28
Related Articles Combined treatment with acetazolamide and cisplatin enhances the chemosensitivity of human head and neck squamous cell carcinoma TU868 cells. Arch Oral Biol. 2020 Sep 09;119:104905 Authors: Jia T, Ming SX, Cao QQ, Xu FL Abstract AIMS: To investigate whether combination of acetazolamide and cisplatin can enhance the chemosensitivity of human head and neck squamous cell carcinoma (HNSCC) cell line TU868. METHODS:...
Sun Sep 20, 2020 06:28
Related Articles The Treatment of Cholesteatomas Involving the Antrum and Mastoid Using Transcanal Underwater Endoscopic Ear Surgery. Otol Neurotol. 2020 Sep 17;: Authors: Chen Y, Hu J, Liu W, Wang Q, Li Y, Peng A, Zhang Z Abstract OBJECTIVE: The aim of this study was to evaluate the feasibility and safety of transcanal underwater endoscopic bone resection (TUEBR) of the external auditory canal (EAC) for the management of cholesteatoma...
Sun Sep 20, 2020 06:28
Related Articles Middle Cranial Fossa Approach to Vestibular Schwannoma Resection in the Older Patient Population. Otol Neurotol. 2020 Sep 16;: Authors: Kohlberg GD, Lipschitz N, Raghavan AM, Breen JT, Pensak ML, Zuccarello M, Samy RN Abstract OBJECTIVE: Compare outcomes of middle cranial fossa approach (MCF) to vestibular schwannoma (VS) resection in patients 60 years of age and older to patients under 60. STUDY DESIGN: Retrospective...
Sun Sep 20, 2020 06:28
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