Related Articles Wnt Signaling Regulates Ipsilateral Pathfinding in The Zebrafish Forebrain through slit3. Neuroscience. 2020 Sep 16;: Authors: Zhang Q, Zhang C, Zhang C, Peng G Abstract The nervous system relies upon correct interconnections to exert its normal function. During vertebrate embryonic development, highly stereotyped scaffolds of axon tracts are formed early in the brain to set the foundation for the neuronal interconnections....
Sun Sep 20, 2020 14:31
Related Articles Palbociclib and trastuzumab in HER2-positive advanced breast cancer: Results from the phase II SOLTI-1303 PATRICIA trial. Clin Cancer Res. 2020 Sep 16;: Authors: Ciruelos EM, Villagrasa P, Pascual T, Oliveira M, Pernas S, Paré L, Escrivá-de-Romaní S, Manso L, Adamo B, Martínez de Dueñas E, Cortés J, Vázquez S, Perelló A, Garau I, Melé M, Martínez Jañez N, Montaño A, Bermejo B, Morales S, Echarri MJ, Vega E, González-Farré B, Martínez D, Galván...
Fri Sep 18, 2020 13:44
Related Articles Recognition of the organ-specific mutations in metastatic breast cancer by circulating tumor cells isolated in vivo. Neoplasma. 2020 Sep 17;: Authors: Li S, Yang S, Shi J, Ding Y, Gao W, Cheng M, Sun Y, Xie Y, Sang M, Yang H, Geng C Abstract The failure to treat and control the growth of metastases is the main cause of death in breast cancer (BC) patients. Compared to the traditional method of analyzing circulating tumor DNA...
Fri Sep 18, 2020 17:45
Related Articles Circulating miRNAs in HER2-Positive and Triple Negative Breast Cancers: Potential Biomarkers and Therapeutic Targets. Int J Mol Sci. 2020 Sep 15;21(18): Authors: Gupta I, Rizeq B, Vranic S, Moustafa AA, Al Farsi H Abstract Breast cancer is one of the most prevalent diseases among women worldwide and is highly associated with cancer-related mortality. Of the four major molecular subtypes, HER2-positive and triple-negative breast...
Sun Sep 20, 2020 09:36
Related Articles Breast cancer prognosis and P-cadherin expression: systematic review and study-level meta-analysis. BMJ Support Palliat Care. 2020 Sep 17;: Authors: Qi R, Lin J, Chen S, Jiang J, Zhang X, Yao B, Zheng H, Jin Z, Yuan Y, Hou W, Hua B, Guo Q Abstract OBJECTIVE: P-cadherin can act both as a tumour suppressor and an oncogene. The clinical prognostic value of P-cadherin overexpression in breast cancer (BC) remains unclear. We conducted...
Sun Sep 20, 2020 09:36
Related Articles Pathological Complete Response from Pyrotinib Combined with Trastuzumab, Paclitaxel and Cisplatin in a Postpartum Woman with HER2-Positive Locally Advanced Breast Cancer: A Case Report. Onco Targets Ther. 2020;13:8749-8756 Authors: He L, Zhang F, Ma Y, Zuo L, Xu Y Abstract Background: Overexpression of human epidermal growth factor receptor 2 (HER2) is associated with aggressive disease and poor prognosis. Traditional HER2-targeted...
Sun Sep 20, 2020 09:36
Related Articles Elaeagnus angustifolia Plant Extract Inhibits Epithelial-Mesenchymal Transition and Induces Apoptosis via HER2 Inactivation and JNK Pathway in HER2-Positive Breast Cancer Cells. Molecules. 2020 Sep 16;25(18): Authors: Jabeen A, Sharma A, Gupta I, Kheraldine H, Vranic S, Al Moustafa AE, Al Farsi HF Abstract Elaeagnus angustifolia (EA) is a medicinal plant used for treating several human diseases in the Middle East. Meanwhile,...
Sun Sep 20, 2020 13:36
Related Articles The prognostic and predictive role of the neutrophil-to-lymphocyte ratio and the monocyte-to-lymphocyte ratio in early breast cancer, especially in the HER2+ subtype. Breast Cancer Res Treat. 2020 Sep 18;: Authors: Tiainen S, Rilla K, Hämäläinen K, Oikari S, Auvinen P Abstract PURPOSE: The aim of this study was to investigate the prognostic impact of two systemic inflammatory markers, the neutrophil-to-lymphocyte ratio (NLR)...
Sun Sep 20, 2020 13:36
Related Articles A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activity. EBioMedicine. 2020 Sep 16;60:102996 Authors: Ding X, Gu W, Zhong Y, Hao X, Liu J, Xia S, Luo L, Chen M, Zhang C Abstract BACKGROUND: Pertuzumab is currently used in combination with trastuzumab as the first-line treatment for HER2-positive metastatic breast cancer. However, pertuzumab was...
Sun Sep 20, 2020 17:40
Related Articles Surveillance of cohesin-supported chromosome structure controls meiotic progression. Nat Commun. 2020 08 28;11(1):4345 Authors: Castellano-Pozo M, Pacheco S, Sioutas G, Jaso-Tamame AL, Dore MH, Karimi MM, Martinez-Perez E Abstract Chromosome movements and programmed DNA double-strand breaks (DSBs) promote homologue pairing and initiate recombination at meiosis onset. Meiotic progression involves checkpoint-controlled termination...
Fri Sep 18, 2020 13:38
Related Articles Transient Receptor Potential Ankyrin-1 (TRPA1) and Vanilloid-3 (TRPV3) Differentially Regulate Endoplasmic Reticulum Stress and Cytotoxicity in Human Lung Epithelial Cells Following Pneumotoxic Wood Smoke Particle Exposure. Mol Pharmacol. 2020 Sep 16;: Authors: Nguyen ND, Memon TA, Burrell KL, Almestica-Roberts M, Rapp E, Sun L, Scott AF, Deering-Rice C, Rower JE, Reilly CA Abstract This study investigated the roles of...
Fri Sep 18, 2020 13:38
Related Articles Copaifera spp. oleoresins impair Toxoplasma gondii infection in both human trophoblastic cells and human placental explants. Sci Rep. 2020 Sep 16;10(1):15158 Authors: Teixeira SC, de Souza G, Borges BC, de Araújo TE, Rosini AM, Aguila FA, Ambrósio SR, Veneziani RCS, Bastos JK, Silva MJB, Martins CHG, de Freitas Barbosa B, Ferro EAV Abstract The combination of pyrimethamine and sulfadiazine is the standard care in cases...
Fri Sep 18, 2020 13:38
Related Articles Expression of Rab3b in Human Glioma: Influence on Cell Proliferation and Apoptosis. Curr Pharm Des. 2020 Sep 17;: Authors: Luo Q, Liu Y, Yuan Z, Huang L, Diao B Abstract BACKGROUND: Glioma is the most common human central nervous system tumour with a high degree of malignancy. Some Rab GTPases have significant effects on glioma. OBJECTIVE: This study aimed to investigate the effect of Rab3b (Rab GTPase3b) on human...
Fri Sep 18, 2020 14:37
Related Articles MAPK activity dynamics regulate non-cell autonomous effects of oncogene expression. Elife. 2020 Sep 17;9: Authors: Aikin TJ, Peterson AF, Pokrass MJ, Clark HR, Regot S Abstract A large fraction of human cancers contain genetic alterations within the Mitogen Activated Protein Kinase (MAPK) signaling network that promote unpredictable phenotypes. Previous studies have shown that the temporal patterns of MAPK activity (i.e....
Fri Sep 18, 2020 14:37
Related Articles Sodium orthovanadate inhibits growth of acute leukemia HL60 cells and HL60/A cells In vitro. Biosci Rep. 2020 Sep 17;: Authors: Zhang L, Wei N, Guan G, Song T, Xu Y, Wang S, Zhou J Abstract Vanadium is an ultratrace element. The transition metal vanadium, widely existed in the environment and exhibits various biological and physiological effects in the human body, yet with no presently known specific physiological function...
Fri Sep 18, 2020 14:37
Related Articles Inhibition of EZH2 via the STAT3/HOTAIR signalling axis contributes to cell cycle arrest and apoptosis induced by polyphyllin I in human non-small cell lung cancer cells. Steroids. 2020 Sep 14;:108729 Authors: Shing Li H, Xu Y Abstract OBJECTIVE: To explore the potential mechanism of polyphyllin I (PPI)-induced apoptosis in lung cancer cells. METHODS AND MATERIALS: The pathological changes in lung cancer tissues...
Fri Sep 18, 2020 14:37
Related Articles The synthesis and anti-tumour properties of novel 4-substituted phthalazinones as Aurora B kinase inhibitors. Bioorg Med Chem Lett. 2020 Sep 14;:127556 Authors: Zhang XJ, Xu Y, Mou HX, Wang S, Hao SY, Chen SW Abstract A series of novel 4-substituted phthalazinones as Aurora B kinase inhibitors was synthesized and evaluated the anti-proliferative activities against A549, HCT116, MCF-7 and HepG2 cells. 1-(4-(2-((4-Oxo-3,4-dihydrophthalazin-1-yl)amino)ethyl)...
Fri Sep 18, 2020 14:37
Related Articles Prospects of Tangeretin as a modulator of cancer targets/pathways. Pharmacol Res. 2020 Sep 14;:105202 Authors: Raza W, Luqman S, Meena A Abstract To date, cancer is the second leading cause of death worldwide after cardiac arrest. A large number of synthetic drugs are available for the treatment of different types of cancer; however, a major problem associated with these drugs is its toxicity towards the normal cells. To...
Fri Sep 18, 2020 14:37
Related Articles 2-Anilinoquinoline based arylamides as broad spectrum anticancer agents with B-RAFV600E/C-RAF kinase inhibitory effects: Design, synthesis, in vitro cell-based and oncogenic kinase assessments. Eur J Med Chem. 2020 Aug 23;208:112756 Authors: El-Damasy AK, Haque MM, Park JW, Shin SC, Lee JS, EunKyeong Kim E, Keum G Abstract Prompted by the urgent demand for identification of new anticancer agents with improved potency and...
Fri Sep 18, 2020 14:37
Related Articles Structural characteristics of circulating immune complexes in calves with bronchopneumonia: Impact on the quiescent leukocytes. Res Vet Sci. 2020 Sep 09;133:63-74 Authors: Kovačić M, Fratrić N, Arsić A, Mojsilović S, Drvenica I, Marković D, Maslovarić I, Grujić Milanović J, Ivanov M, Ilić V Abstract Calf bronchopneumonia is accompanied by increased level of circulating immune complexes (CIC), and we analysed size, and protein...
Fri Sep 18, 2020 14:37
Related Articles A DNA Repair-Based Model of Cell Survival with Important Clinical Consequences. Radiat Res. 2020 Sep 16;194(3):202-235 Authors: Brahme A Abstract This work provides a description of a new interaction, cross-section-based model for radiation-induced cellular inactivation, sublethal damage, DNA repair and cell survival, with the ability to more accurately elucidate different radiation-response phenomena. The principal goal...
Fri Sep 18, 2020 14:37
Related Articles α-Fodrin is required for the organization of functional microtubules during mitosis. Cell Cycle. 2019 Oct;18(20):2713-2726 Authors: Nellikka RK, Sreeja JS, Dharmapal D, John R, Monteiro A, Macedo JC, Conde C, Logarinho E, Sunkel CE, Sengupta S Abstract The cytoskeleton protein α-fodrin plays a major role in maintaining structural stability of membranes. It was also identified as part of the brain γ-tubulin ring complex, the...
Sun Sep 20, 2020 07:00
Related Articles RecQ DNA Helicase Rqh1 Promotes Rad3ATR Kinase Signaling in the DNA Replication Checkpoint Pathway of Fission Yeast. Mol Cell Biol. 2020 08 14;40(17): Authors: Ahamad N, Khan S, Xu YJ Abstract Rad3 is the orthologue of ATR and the sensor kinase of the DNA replication checkpoint in Schizosaccharomyces pombe Under replication stress, it initiates checkpoint signaling at the forks necessary for maintaining genome stability and...
Sun Sep 20, 2020 07:00
Related Articles 3D Microenvironment Stiffness Regulates Tumor Spheroid Growth and Mechanics via p21 and ROCK. Adv Biosyst. 2019 09;3(9):e1900128 Authors: Taubenberger AV, Girardo S, Träber N, Fischer-Friedrich E, Kräter M, Wagner K, Kurth T, Richter I, Haller B, Binner M, Hahn D, Freudenberg U, Werner C, Guck J Abstract The mechanical properties of cancer cells and their microenvironment contribute to breast cancer progression. While mechanosensing...
Sun Sep 20, 2020 07:00
Related Articles Synthetic Lethal Metabolic Targeting of Androgen Deprived Prostate Cancer Cells with Metformin. Mol Cancer Ther. 2020 Sep 17;: Authors: Yang B, Damodaran S, Khemees TA, Filon MJ, Schultz A, Gawdzik J, Etheridge T, Malin D, Richards KA, Cryns VL, Jarrard DF Abstract The initiation of androgen deprivation therapy (ADT) induces susceptibilities in prostate cancer (PC) cells that make them vulnerable to synergistic treatment...
Sun Sep 20, 2020 07:00
Related Articles Dual inhibition of HDAC and tyrosine kinase signaling pathways with CUDC-907 attenuates TGFβ1 induced lung and tumor fibrosis. Cell Death Dis. 2020 Sep 17;11(9):765 Authors: Zhang W, Zhang Y, Tu T, Schmull S, Han Y, Wang W, Li H Abstract TGFβ1 signaling is a critical driver of collagen accumulation in pulmonary fibrotic diseases and a well-characterized regulator of cancer associated fibroblasts (CAF) activation in lung...
Sun Sep 20, 2020 07:00
Related Articles Reactive oxygen species mediate anlotinib-induced apoptosis via activation of endoplasmic reticulum stress in pancreatic cancer. Cell Death Dis. 2020 Sep 17;11(9):766 Authors: Yang L, Zhou X, Sun J, Lei Q, Wang Q, Pan D, Ding M, Ding Y Abstract Anlotinib (AL3818), a novel multi-targeted receptor tyrosine kinase inhibitor, has recently been proven to be an antitumour drug. This study aimed to explore the antitumour effect...
Sun Sep 20, 2020 07:00
Related Articles Oxidative stress-mediated mitochondrial dysfunction facilitates mesenchymal stem cell senescence in ankylosing spondylitis. Cell Death Dis. 2020 Sep 17;11(9):775 Authors: Ye G, Xie Z, Zeng H, Wang P, Li J, Zheng G, Wang S, Cao Q, Li M, Liu W, Cen S, Li Z, Wu Y, Ye Z, Shen H Abstract Ankylosing spondylitis (AS) is a chronic inflammatory disease possessing a morbid serum microenvironment with enhanced oxidative stress. Long-term...
Sun Sep 20, 2020 07:00
Related Articles Long Noncoding RNA (lncRNA) MT1JP Suppresses Hepatocellular Carcinoma (HCC) in vitro. Cancer Manag Res. 2020;12:7949-7960 Authors: Mo W, Dai Y, Chen J, Liang L, Xu S, Xu X Abstract Introduction: The purpose of this study was to evaluate the effects and mechanisms of the long noncoding RNA (lncRNA) MT1JP on hepatocellular carcinoma (HCC) in vitro. Patients and Methods: Thirty pairs of tumor and adjacent normal...
Sun Sep 20, 2020 07:00
Related Articles An ATF24 peptide-functionalized β-elemene-nanostructured lipid carrier combined with cisplatin for bladder cancer treatment. Cancer Biol Med. 2020 Aug 15;17(3):676-692 Authors: Zhai B, Chen P, Wang W, Liu S, Feng J, Duan T, Xiang Y, Zhang R, Zhang M, Han X, Chen X, Li Q, Li G, Liu Y, Huang X, Zhang W, Pan T, Yan L, Jin T, Xie T, Sui X Abstract Objective: In this study, we aimed to develop an amino-terminal fragment (ATF)...
Sun Sep 20, 2020 07:00
Related Articles Asiaticoside suppresses cell proliferation by inhibiting the NF‑κB signaling pathway in colorectal cancer. Int J Mol Med. 2020 Jul 28;: Authors: Zhou X, Ke C, Lv Y, Ren C, Lin T, Dong F, Mi Y Abstract Colorectal cancer (CRC) is one of the leading causes of cancer‑associated mortality. Asiaticoside (AC) exhibits antitumor effects; however, to the best of our knowledge, the biological function of AC in CRC cells remains unclear....
Sun Sep 20, 2020 07:00
Related Articles Sphingosine‑1‑phosphate analogue FTY720 exhibits a potent anti‑proliferative effect on glioblastoma cells. Int J Oncol. 2020 Aug 25;: Authors: Kolodziej MA, Al Barim B, Nagl J, Weigand MA, Uhl E, Uhle F, Di Fazio P, Schwarm FP, Stein M Abstract Sphingosine‑1‑phosphate (S1P) plays a key role in cell survival, growth, migration, and in angiogenesis. In glioma, it triggers the activity of the S1P‑receptor 1 and of the sphingosine...
Sun Sep 20, 2020 07:00
Related Articles Artesunate inhibits lung cancer cells via regulation of mitochondrial membrane potential and induction of apoptosis. Mol Med Rep. 2020 Jul 15;: Authors: Zhao Y, Liu J, Liu L Abstract Lung cancer is a common malignant disease with a high incidence rate worldwide, posing a great threat to human health. To date, only a small number of studies have assessed the potential anti‑cancer effect of artesunate (Art) and the associated...
Sun Sep 20, 2020 07:00
Related Articles PRMT6 serves an oncogenic role in lung adenocarcinoma via regulating p18. Mol Med Rep. 2020 Aug 03;: Authors: Tang J, Meng Q, Shi R, Xu Y Abstract Lung adenocarcinoma (LUAD), a major subtype of lung cancer, is the leading cause of cancer‑related mortality worldwide. Previous studies have determined the role of the protein arginine methyltransferases (PRMTs) in the physiology and pathology of LUAD. However, to the best of...
Sun Sep 20, 2020 07:00
Related Articles Resveratrol synergizes with cisplatin in antineoplastic effects against AGS gastric cancer cells by inducing endoplasmic reticulum stress‑mediated apoptosis and G2/M phase arrest. Oncol Rep. 2020 Jul 31;: Authors: Ren M, Zhou X, Gu M, Jiao W, Yu M, Wang Y, Liu S, Yang J, Ji F Abstract Gastric cancer (GC) is a common gastrointestinal malignancy, and cisplatin (DDP) is an important component of chemotherapeutic regimens for...
Sun Sep 20, 2020 07:00
Related Articles Efficient proliferation and mitosis of glioblastoma cells infected with human cytomegalovirus is mediated by RhoA GTPase. Mol Med Rep. 2020 Aug 19;: Authors: Al-Qahtani AA, Alarifi S, Alkahtani S, Stournaras C, Sourvinos G Abstract Human cytomegalovirus (HCMV) is a prevalent viral pathogen, which can cause severe clinical consequences in neonates, immunocompromised individuals, patients with AIDS, and organ and stem cell...
Sun Sep 20, 2020 07:00
Related Articles Kevetrin induces apoptosis in TP53 wild‑type and mutant acute myeloid leukemia cells. Oncol Rep. 2020 Aug 11;: Authors: Napolitano R, De Matteis S, Carloni S, Bruno S, Abbati G, Capelli L, Ghetti M, Bochicchio MT, Liverani C, Mercatali L, Calistri D, Cuneo A, Menon K, Musuraca G, Martinelli G, Simonetti G Abstract Tumor protein p53 is a key regulator of several cellular pathways, including DNA repair, cell cycle and angiogenesis....
Sun Sep 20, 2020 07:00
Related Articles Inactivation of AKT/NF‑κB signaling by eurycomalactone decreases human NSCLC cell viability and improves the chemosensitivity to cisplatin. Oncol Rep. 2020 Jul 31;: Authors: Dukaew N, Chairatvit K, Pitchakarn P, Imsumran A, Karinchai J, Tuntiwechapikul W, Wongnoppavich A Abstract The high activation of protein kinase B (AKT)/nuclear factor‑κB (NF‑κB) signaling has often been associated with the induction of non‑small cell...
Sun Sep 20, 2020 07:00
Related Articles Sensitivity of human papillomavirus‑positive and ‑negative oropharyngeal cancer cell lines to ionizing irradiation. Oncol Rep. 2020 Jul 31;: Authors: Holzhauser S, Pirotte E, Jones J, Owens D, Al-Hussaini A, Giles P, Evans M, Man S, Powell N Abstract Human papillomavirus‑positive (HPV+) oropharyngeal squamous cell carcinoma (OPSCC) has increased in incidence and has a much better prognosis than HPV‑negative (HPV‑) OPSCC...
Sun Sep 20, 2020 07:00
Related Articles Expression and role of p16 and GLUT1 in malignant diseases and lung cancer: A review. Thorac Cancer. 2020 Sep 18;: Authors: Pezzuto A, D'Ascanio M, Ricci A, Pagliuca A, Carico E Abstract Non-small cell lung cancer (NSCLC) is the leading cause of cancer death and in most cases it is often diagnosed at an advanced stage. Many genetic and microenvironmental factors are able to modify the cell cycle inducing carcinogenesis...
Sun Sep 20, 2020 07:00
Related Articles Transcriptomics predicts compound synergy in drug and natural product treated glioblastoma cells. PLoS One. 2020;15(9):e0239551 Authors: Pruteanu LL, Kopanitsa L, Módos D, Kletnieks E, Samarova E, Bender A, Gomez LD, Bailey DS Abstract Pathway analysis is an informative method for comparing and contrasting drug-induced gene expression in cellular systems. Here, we define the effects of the marine natural product fucoxanthin,...
Sun Sep 20, 2020 07:00
Related Articles RBM10, a New Regulator of p53. Cells. 2020 Sep 16;9(9): Authors: Jung JH, Lee H, Zeng SX, Lu H Abstract The tumor suppressor p53 acts as a transcription factor that regulates the expression of a number of genes responsible for DNA repair, cell cycle arrest, metabolism, cell migration, angiogenesis, ferroptosis, senescence, and apoptosis. It is the most commonly silenced or mutated gene in cancer, as approximately 50% of...
Sun Sep 20, 2020 13:59
Related Articles Antiproliferative and Pro-Apoptotic Effect of Uvaol in Human Hepatocarcinoma HepG2 Cells by Affecting G0/G1 Cell Cycle Arrest, ROS Production and AKT/PI3K Signaling Pathway. Molecules. 2020 Sep 16;25(18): Authors: Bonel-Pérez GC, Pérez-Jiménez A, Gris-Cárdenas I, Parra-Pérez AM, Lupiáñez JA, Reyes-Zurita FJ, Siles E, Csuk R, Peragón J, Rufino-Palomares EE Abstract Natural products have a significant role in the development...
Sun Sep 20, 2020 13:59
Related Articles Relevance of the combination of external beam radiotherapy with the hypoxia-activated prodrug ICF05016 in an experimental model of extraskeletal myxoid chondrosarcoma. Invest New Drugs. 2020 Sep 18;: Authors: Maubert E, Weber V, Voissière A, Gérard Y, Dedieu V, Degoul F, Chezal JM, Chautard E, Miot-Noirault E Abstract Currently, there is no gold standard treatment for Extraskeletal Myxoid Chondrosarcomas (EMC) making wide...
Sun Sep 20, 2020 13:59
Related Articles Therapeutic potential and molecular mechanisms of mycophenolic acid as an anticancer agent. Eur J Pharmacol. 2020 Sep 16;:173580 Authors: Benjanuwattra J, Chaiyawat P, Pruksakorn D, Koonrungsesomboon N Abstract Mycophenolic acid (MPA) is the active metabolite of mycophenolate mofetil (MMF), an immunosuppressive drug approved for the prophylaxis of allograft rejection in transplant recipients. Recent advances in the role...
Sun Sep 20, 2020 14:58
New England Journal of Medicine, Ahead of Print.
Fri Sep 18, 2020 10:00
New England Journal of Medicine, Ahead of Print.
Sat Sep 19, 2020 07:30
Related Articles Application of Plasma Exchange in Steroid-Responsive Encephalopathy. Front Immunol. 2019;10:324 Authors: Jiang Y, Tian X, Gu Y, Li F, Wang X Abstract Plasma exchange has been widely used in autoimmune neurological diseases and is the standard treatment for myasthenia gravis crisis and Guillain-Barre syndrome. A growing body of research suggests that, in the clinical application of steroid-responsive encephalopathy, such as...
Fri Sep 18, 2020 15:46
Related Articles Evaluation of Cardiac Repolarization Indices in Epilepsy Patients Treated with Carbamazepine and Valproic Acid. Medicina (Kaunas). 2020 Jan 06;56(1): Authors: Asoğlu R, Özdemir M, Aladağ N, Asoğlu E Abstract BACKGROUND AND OBJECTIVES: Epilepsy patients have a higher risk of sudden unexplained death compared to the rest of the population. Cardiac repolarization abnormalities might be seen in epilepsy during interictal periods....
Fri Sep 18, 2020 15:46
Related Articles Incidence and case fatality rate of COVID-19 in patients with active epilepsy. Neurology. 2020 09 08;95(10):e1417-e1425 Authors: Cabezudo-García P, Ciano-Petersen NL, Mena-Vázquez N, Pons-Pons G, Castro-Sánchez MV, Serrano-Castro PJ Abstract OBJECTIVE: This article estimates the incidence and fatality of coronavirus disease 2019 (COVID-19) and identifies potential risk factors for fatality in patients with active epilepsy....
Fri Sep 18, 2020 15:46
Related Articles Neuroinflammation and progressive myoclonus epilepsies: from basic science to therapeutic opportunities. Expert Rev Mol Med. 2020 Sep 17;22:e4 Authors: Sanz P, Serratosa JM Abstract Progressive myoclonus epilepsies (PMEs) are a group of genetic neurological disorders characterised by the occurrence of epileptic seizures, myoclonus and progressive neurological deterioration including cerebellar involvement and dementia. The primary...
Fri Sep 18, 2020 15:46
Related Articles Changes in access to educational and healthcare services for individuals with intellectual and developmental disabilities during COVID-19 restrictions. J Intellect Disabil Res. 2020 Sep 17;: Authors: Jeste S, Hyde C, Distefano C, Halladay A, Ray S, Porath M, Wilson RB, Thurm A Abstract BACKGROUND: COVID-19 restrictions have significantly limited access to in-person educational and healthcare services for all, including individuals...
Fri Sep 18, 2020 15:46
Related Articles Sirolimus as a Potential Treatment for Sturge-Weber Syndrome. J Craniofac Surg. 2020 Sep 15;: Authors: Sun B, Han T, Wang Y, Gao Q, Cui J, Shen W Abstract BACKGROUND: Sturge-Weber syndrome (SWS) is a rare neurocutaneous syndrome characterized by port-wine stain, leptomeningeal angiomatosis, and glaucoma. Due to the involvement of the nervous system, patients are often accompanied with epilepsy. It reported that 75% of patients...
Fri Sep 18, 2020 15:46
Related Articles Gabapentin treatment in a patient with KCNQ2 developmental epileptic encephalopathy. Pharmacol Res. 2020 Sep 14;:105200 Authors: Soldovieri MV, Freri E, Ambrosino P, Rivolta I, Mosca I, Binda A, Murano C, Ragona F, Canafoglia L, Vannicola C, Solazzi R, Granata T, Castellotti B, Messina G, Gellera C, Labalme A, Lesca G, DiFrancesco JC, Taglialatela M Abstract DE NOVO: variants in KCNQ2 encoding for Kv7.2 voltage-dependent neuronal...
Fri Sep 18, 2020 15:46
Related Articles Efficacy of vagus nerve stimulation for drug-resistant epilepsy in children age six and younger. Epilepsy Behav. 2020 Sep 14;112:107373 Authors: Muthiah N, Zhang J, Remick M, Welch W, Sogawa Y, Jeong JH, Abel TJ Abstract OBJECTIVES: The objective of the study were to examine the safety and efficacy of vagus nerve stimulation (VNS) for reducing seizure frequency and antiepileptic drugs (AEDs) in children younger than six years...
Fri Sep 18, 2020 15:46
Related Articles Virtual Reality-Assisted Pain, Anxiety, and Anger Management in the Emergency Department. Telemed J E Health. 2019 12;25(12):1207-1215 Authors: Sikka N, Shu L, Ritchie B, Amdur RL, Pourmand A Abstract Study Objective: Pain management in emergency department (ED) patients is challenging. Although both pharmacological and nonpharmacological therapies exist, they are often suboptimal. Immersive virtual reality (VR) uses distraction...
Sun Sep 20, 2020 07:58
Related Articles Tacrolimus protects hippocampal neurons of rats with status epilepticus through suppressing oxidative stress and inhibiting mitochondrial pathway of apoptosis. Brain Res. 2019 07 15;1715:176-181 Authors: Wang A, Si Z, Xue P, Li X, Liu J Abstract OBJECTIVE: To investigate the mechanisms underlying the neuroprotective effect of tacrolimus (FK506) on the hippocampal neurons of rats with status epilepticus (SE). METHOD:...
Sun Sep 20, 2020 07:58
Related Articles Genomic and Personalized Medicine Perspective in Genetic Generalized Epilepsy. Arch Iran Med. 2019 09 01;22(9):516-526 Authors: Torabian P, Dehestani M, Morshedi Rad D, Peiravi S, Aghaie-Hakkak M, Ashraf H Abstract The genetic generalized epilepsies (GGEs) are a set of disorders presenting with generalized seizures, in addition to general spike-wave activity. The present study aims to investigate the clinical manifestations...
Sun Sep 20, 2020 07:58
Related Articles Clinical analysis of reversible splenial lesion syndrome in Chinese adults: A retrospective study of 11 cases. Medicine (Baltimore). 2020 Sep 04;99(36):e22052 Authors: Gao X, Feng Q, Arif S, Liaqat J, Li B, Jiang K Abstract Reversible splenial lesion syndrome (RESLES) is a clinico-radiological entity that defines a reversible lesion in the splenium of the corpus callosum (SCC) on magnetic resonance imaging (MRI). The clinical...
Sun Sep 20, 2020 07:58
Related Articles Youth Weigh In: Views on Advanced Neurotechnology for Drug-Resistant Epilepsy. J Child Neurol. 2020 Sep 17;:883073820957810 Authors: Udwadia FR, McDonald PJ, Connolly MB, Hrincu V, Illes J Abstract BACKGROUND: Epilepsy affects over 500,000 children in North America of whom 30% have drug-resistant epilepsy. Advancements with neurotechnologies show promising benefits, but the perceptions of these procedures by youth is unknown....
Sun Sep 20, 2020 07:58
Related Articles Changes in caregiver depression, anxiety, and satisfaction with family relationships in families of children who did and did not undergo resective epilepsy surgery. Epilepsia. 2020 Sep 17;: Authors: Phillips NL, Widjaja E, Smith ML Abstract OBJECTIVE: To evaluate longitudinal changes in caregiver depression, anxiety, and family relationships following resective surgery for pediatric drug-resistant epilepsy (DRE). METHODS:...
Sun Sep 20, 2020 07:58
Related Articles Long-term efficacy and safety of eslicarbazepine acetate monotherapy for adults with newly diagnosed focal epilepsy: An open-label extension study. Epilepsia. 2020 Sep 17;: Authors: Trinka E, Rocamora R, Chaves J, Moreira J, Ikedo F, Soares-da-Silva P, BIA-2093-311/EXT Investigators Study Group Abstract OBJECTIVE: To assess the efficacy, safety, and tolerability of eslicarbazepine acetate (ESL) monotherapy during long-term treatment....
Sun Sep 20, 2020 07:58
Related Articles Seizure-onset regions demonstrate high inward directed connectivity during resting-state: An SEEG study in focal epilepsy. Epilepsia. 2020 Sep 18;: Authors: Narasimhan S, Kundassery KB, Gupta K, Johnson GW, Wills KE, Goodale SE, Haas K, Rolston JD, Naftel RP, Morgan VL, Dawant BM, González HFJ, Englot DJ Abstract OBJECTIVE: In patients with medically refractory focal epilepsy, stereotactic-electroencephalography (SEEG) can aid...
Sun Sep 20, 2020 07:58
Related Articles Odor identification predicts postoperative seizure control following magnetic resonance-guided laser interstitial thermal therapy. Epilepsia. 2020 Sep 17;: Authors: Kang JY, Yenokyan G, Hwang BY, Chen M, Penn R, Mampre D, Sperling MR, Kamath V Abstract OBJECTIVE: Olfactory dysfunction has been well documented in individuals with temporal lobe epilepsy, but its use in presurgical planning has yet to be examined. We assessed the...
Sun Sep 20, 2020 07:58
Related Articles Effects of zonisamide monotherapy on bone health in drug-naive epileptic patients. Epilepsia. 2020 Sep 18;: Authors: Koo DL, Nam H Abstract OBJECTIVE: Alteration of bone strength is an adverse effect of antiepileptic drug treatment. We investigated the effects of zonisamide (ZNS) monotherapy on bone mineral density (BMD) and biomarkers of bone metabolism after 13 months of treatment in drug-naive epileptic patients. ...
Sun Sep 20, 2020 07:58
Related Articles MicroRNAs and target genes in epileptogenesis. Epilepsia. 2020 Sep 18;: Authors: Feng Y, Yang H, Yue Y, Tian F Abstract Epilepsy is a chronic brain dysfunction. Current antiepileptic medicines cannot prevent epileptogenesis. Increasing data have shown that microRNAs (miRNAs) are selectively altered within the epileptic hippocampi of experimental models and human tissues, and these alterations affect the genes that control epileptogenesis....
Sun Sep 20, 2020 07:58
Related Articles Safety and tolerability associated with chronic intermittent use of diazepam buccal film in adult, adolescent, and pediatric patients with epilepsy. Epilepsia. 2020 Sep 17;: Authors: Seinfeld S, Gelfand MA, Heller AH, Buan C, Slatko G Abstract OBJECTIVE: Diazepam buccal film (DBF) is in development for treatment of patients experiencing bouts of increased seizure activity. We assessed safety, tolerability, and usability of self-...
Sun Sep 20, 2020 07:58
Related Articles miR‑15a inhibits cell apoptosis and inflammation in a temporal lobe epilepsy model by downregulating GFAP. Mol Med Rep. 2020 Jul 30;: Authors: Fan Y, Wang W, Li W, Li X Abstract Temporal lobe epilepsy (TLE) is a type of epilepsy, which is associated with high morbidity and recurrence rates, and is also difficult to treat. Therefore, it is important to identify novel treatments for TLE. In recent years, with the development of...
Sun Sep 20, 2020 07:58
Related Articles Efficacy and safety of Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: A real-world study. Epilepsia. 2020 Sep 18;: Authors: Specchio N, Pietrafusa N, Doccini V, Trivisano M, Darra F, Ragona F, Cossu A, Spolverato S, Battaglia D, Quintiliani M, Luigia Gambardella M, Rosati A, Mei D, Granata T, Dalla Bernardina B, Vigevano F, Guerrini R Abstract OBJECTIVE: Dravet syndrome (DS) is a drug-resistant,...
Sun Sep 20, 2020 07:58
Related Articles Verbal memory dysfunction is associated with alterations in brain transcriptome in dominant temporal lobe epilepsy. Epilepsia. 2020 Sep 18;: Authors: Busch RM, Yehia L, Bazeley P, Seyfi M, Blümcke I, Hermann BP, Najm IM, Eng C Abstract OBJECTIVE: Memory dysfunction is prevalent in many neurological disorders and can have a significant negative impact on quality of life. The genetic contributions to memory impairment in epilepsy,...
Sun Sep 20, 2020 07:58
Related Articles Discovery of Vixotrigine: A Novel Use-Dependent Sodium Channel Blocker for the Treatment of Trigeminal Neuralgia. ACS Med Chem Lett. 2020 Sep 10;11(9):1678-1687 Authors: Witty DR, Alvaro G, Derjean D, Giblin GMP, Gunn K, Large C, Macpherson DT, Morisset V, Owen D, Palmer J, Rugiero F, Tate S, Hinckley CA, Naik H Abstract Drugs that block voltage-gated sodium channels (NaVs) have utility in treating conditions including pain,...
Sun Sep 20, 2020 07:58
Related Articles Evaluation of the interrater and intermethod agreement of the German multiparametric ultrasound criteria for the grading of internal carotid artery stenosis. Neuroradiology. 2020 Sep 18;: Authors: Richter C, Weinreich A, Mucha S, Saur D, Pelz JO Abstract PURPOSE: The interdisciplinary German guidelines for the diagnosis and treatment of internal carotid artery stenosis (ICAS) recommend a multiparametric approach for the sonographic...
Sun Sep 20, 2020 07:58
Related Articles Prevalence and predictors of post-stroke epilepsy among Ghanaian stroke survivors. J Neurol Sci. 2020 Sep 12;418:117138 Authors: Sarfo FS, Akassi J, Obese V, Adamu S, Agbenorku M, Ovbiagele B Abstract BACKGROUND: Post-stroke epilepsy (PSE) is associated with poorer quality of life, higher mortality, and greater health expenditures. We are unaware of any published reports on the frequency of and factors associated with PSE in...
Sun Sep 20, 2020 07:58
Related Articles Quality of life in patients with epilepsy or psychogenic nonepileptic seizures and the contribution of psychiatric comorbidities. Epilepsy Behav. 2020 Sep 15;112:107447 Authors: Avalos JC, Silva BA, Tevés Echazu MF, Rosso B, Besocke AG, Del Carmen Garcia M Abstract Epilepsy is a common neurological disorder, and psychogenic nonepileptic seizures (PNES) is an important differential diagnosis. Psychiatric comorbidities are prevalent...
Sun Sep 20, 2020 07:58
Related Articles Impact of Early Initiation of Eslicarbazepine Acetate on Economic Outcomes Among Patients with Focal Seizure: Results from Retrospective Database Analyses. Neurol Ther. 2020 Sep 19;: Authors: Mehta D, Davis M, Epstein AJ, Wensel B, Grinnell T, Williams GR Abstract INTRODUCTION: This study assessed the association between early initiation of eslicarbazepine acetate (ESL) as first-line therapy (1L cohort) or as first adjunctive...
Sun Sep 20, 2020 14:10
Related Articles Spectral power of interictal EEG in the diagnosis and prognosis of idiopathic generalized epilepsies. Epilepsy Behav. 2020 Sep 16;112:107427 Authors: Pegg EJ, Taylor JR, Mohanraj R Abstract INTRODUCTION: Idiopathic generalized epilepsies (IGE) are characterized by generalized interictal epileptiform discharges (IEDs) on a normal background electroencephalography (EEG). However, the yield of IEDs can be low. Approximately 20%...
Sun Sep 20, 2020 17:11
Related Articles Prevalence and incidence of vertebral fractures: a 7-year follow-up study in institutionalized adults with refractory epilepsy and intellectual disability. Epilepsy Res. 2020 Sep 10;167:106461 Authors: Berkvens J, Majoie M, Mergler S, Beerhorst K, Verschuure P, Tan I, den Bergh JV Abstract OBJECTIVE: The main objective of this cohort study is to determine the prevalence and incidence of morphometric vertebral fractures (VFs)...
Sun Sep 20, 2020 17:11
Related Articles Familial mesial temporal lobe epilepsy in Mexico: Inheritance pattern and clinical features. Epilepsy Res. 2020 Sep 01;167:106450 Authors: Guzmán-Jiménez DE, Campos JB, Venegas-Vega CA, Sánchez MA, Velasco AL Abstract PURPOSE: The objectives of this study were to determine the inheritance pattern by which familial mesial temporal lobe epilepsy (FMTLE) is segregated in Mexican families, and to identify if there was an association...
Sun Sep 20, 2020 17:11
Related Articles BODY MASS INDEX AND OVERALL OUTCOME FOLLOWING SUBARACHNOID HEMORRHAGE: AN OBESITY PARADOX? World Neurosurg. 2020 Sep 14;: Authors: Damodara N, Amuluru K, Nuoman R, Bowers CA, Khandelwal P, Moseley S, Al-Shammari H, El-Ghanem M, Gandhi CD, Al-Mufti F Abstract BACKGROUND: Conventional understanding of obesity demonstrates negative consequences to overall health, while more modern studies have found that it can provide certain...
Fri Sep 18, 2020 16:09
Related Articles Multiple Layer Lumbosacral Pseudomeningocele Repair with Bilateral Paraspinous Muscle Flaps, and Literature Review. World Neurosurg. 2020 Sep 14;: Authors: Banerjee C, Cross B, Rumley J, Devine J, Ritter E, Vender J Abstract BACKGROUND: The pseudomeningocele is an uncommon but widely recognized complication of spinal surgery that can be challenging to correct. When conservative measures fail, patients frequently require re-operation...
Fri Sep 18, 2020 16:09
Related Articles Surgical management for craniocervical junction arteriovenous fistula targeting the intradural feeder. World Neurosurg. 2020 Sep 14;: Authors: Goto Y, Hino A, Shigeomi Y, Oka H PMID: 32942059 [PubMed - as supplied by publisher]
Fri Sep 18, 2020 16:09
Related Articles Single-stage posterior circumferential stabilization using double small cages for the treatment of thoracic and lumbar spine fractures. World Neurosurg. 2020 Sep 16;: Authors: Han MS, Lee SS, Lee SK, Jang JW, Moon BJ, Lee JK Abstract OBJECTIVE: Controversy remains regarding the optimal methods for resection of the vertebral body, reconstruction of the anterior column, and decompression of the spinal cord in patients who have...
Sun Sep 20, 2020 14:24
Related Articles The Effects of Surgery and Adjuvant Therapy on Survival Outcomes in Clear Cell Ependymomas: A Systematic Review and Meta-Analysis of Individual Patient Data. World Neurosurg. 2020 Sep 16;: Authors: Sheen Kweh BT, Rosenfeld J, Hunn M, Tee JW Abstract BACKGROUND: The survival outcomes of clear cell ependymomas is poorly understood. This study clarifies the role of surgery and adjuvant therapy when this morphologically distinct...
Sun Sep 20, 2020 14:24
Related Articles Acute management of gamma knife radiosurgery for asymptomatic obstructive hydrocephalus associated with posterior fossa metastases. World Neurosurg. 2020 Sep 16;: Authors: Matsunaga S, Shuto T, Kobayashi N, Murata H, Yamamoto T Abstract OBJECTIVE: We retrospectively assessed the effectiveness and safety of gamma knife radiosurgery (GKRS) for asymptomatic obstructive hydrocephalus associated with posterior fossa metastases, which...
Sun Sep 20, 2020 14:24
Related Articles The Brain is Not Flat: Conformal Electrode Arrays Diminish Complications of Subdural Electrode Implantation, a Series of 117 Cases. World Neurosurg. 2020 Sep 16;: Authors: Tong BA, Esquenazi Y, Johnson J, Zhu P, Tandon N Abstract BACKGROUND: Intracranial recordings are integral to evaluating patients with pharmaco-resistant epilepsy whom non-invasive testing fails to localize seizure focus. Although stereo-electroencephalography...
Sun Sep 20, 2020 14:24
Related Articles Neurosurgical services in the Northern Zone of Sarawak in Malaysia: The way forward amid COVID-19 pandemic. World Neurosurg. 2020 Sep 16;: Authors: Low PH, Mangat MS, San Liew DN, Hieng Wong AS Abstract BACKGROUND: The novel coronavirus disease 2019 (COVID-19) pandemic has set a huge challenge to the delivery of neurosurgical services including the transfer of patients. We aimed to share our strategy in handling neurosurgical...
Sun Sep 20, 2020 14:24
Related Articles Long-term outcomes of elderly patients with poor-grade aneurysmal subarachnoid hemorrhage. World Neurosurg. 2020 Sep 16;: Authors: Yoshikawa S, Kamide T, Kikkawa Y, Suzuki K, Ikeda T, Kohyama S, Kurita H Abstract OBJECTIVE: Long-term outcomes after surgical treatment and intensive care have not been investigated in elderly patients with poor-grade aneurysmal subarachnoid hemorrhage (aSAH). This study aimed to analyze 12-month...
Sun Sep 20, 2020 14:24
Related Articles Inflammatory demyelinating lesions: true sentinel lesion or immune-mediated response to lymphoma? World Neurosurg. 2020 Sep 16;: Authors: Qiu T, Chanchotisatien A, Qin Z, Wu J, Chu S Abstract BACKGROUND: Inflammatory demyelinating changes in the absence of malignant cells can sometimes be found on initial biopsies preceding the diagnosis of primary central nervous lymphoma (PCNSL), resulting in the term 'sentinel' lesion. Sentinel...
Sun Sep 20, 2020 14:24
Related Articles Surgical Management of Giant Intracranial Aneurysms: Overall Results of a Large Series. World Neurosurg. 2020 Sep 16;: Authors: Luzzi S, Gragnaniello C, Lucifero AG, Del Maestro M, Galzio R PMID: 32949801 [PubMed - as supplied by publisher]
Sun Sep 20, 2020 14:24
Related Articles Ruptured Isolated aneurysm of a coronal branch of the anterior spinal artery. Case report and discussion of treatment strategies. World Neurosurg. 2020 Sep 16;: Authors: Turrini A, D'Andrea M, Antonelli V, Tosatto L Abstract BACKGROUND: Isolated spinal artery aneurysms are an extremely rare cause of subarachnoid hemorrhage. A limited number of case reports and case series have been reported in the literature, and for the uncertain...
Sun Sep 20, 2020 14:24
Related Articles Radiofrequency ablation through previously effective deep brain stimulation leads for Parkinson's disease: A retrospective series. World Neurosurg. 2020 Sep 16;: Authors: Stern MA, Isbaine F, Qiu D, Riley JP, Boulis NM, Gross RE Abstract BACKGROUND: While deep brain stimulation (DBS) of the subthalamic nucleus (STN) or globus pallidus internus (GPi) is the current surgical method of choice to treat the canonical symptoms of...
Sun Sep 20, 2020 14:24
Related Articles Raphael Acquaviva: the forgotten pioneer of modern neurosurgery in Morocco. World Neurosurg. 2020 Sep 16;: Authors: Akhaddar A Abstract For the young generations, it is important to state the values that define and recognize the role of leaders and pioneers in neurosurgery especially in developing countries. This subject seems often overlooked. In Morocco, the real birth of modern neurosurgery as an independent surgical specialty...
Sun Sep 20, 2020 14:24
Related Articles Congenital Midline Spinal Hamartoma in a 5-month-old Infant. World Neurosurg. 2020 Sep 16;: Authors: Malelak EB, Lauren C, Argie D, Nugraheni T Abstract BACKGROUND: Congenital midline spinal hamartoma is a very rare tumor-like proliferation that mostly occurred during childhood. It consists of mature, well-differentiated ectodermal and mesodermal elements that present in an abnormal location and mostly associated with neurofibromatosis...
Sun Sep 20, 2020 14:24
Related Articles Peri-operative Assessment of Cerebellar Masses and the Potential for Cerebellar Cognitive Affective Syndrome: A Review of the Literature. World Neurosurg. 2020 Sep 16;: Authors: Sankey EW, Srinivasan ES, Mehta VA, Bergin SM, Wang TY, Thompson EM, Fecci PE, Friedman AH Abstract The cerebellum was long perceived to be a region of limited importance with primary functions in the regulation of motor control. A degree of its functional...
Sun Sep 20, 2020 14:24
Related Articles Posting a pericranial flap through a "letterbox" into the frontal bone to reconstruct an anterior cranial defect: a new approach. Br J Oral Maxillofac Surg. 2020 01;58(1):118-119 Authors: Pilkington RJJ, Aculate NR, Gahir D, Isles M PMID: 31718914 [PubMed - indexed for MEDLINE]
Fri Sep 18, 2020 14:06
Related Articles Case Report: Temporal Bone Lesion Extending Into Infratemporal Fossa. J Oral Maxillofac Surg. 2020 04;78(4):e17-e20 Authors: Lazar A, Brookes C PMID: 32229022 [PubMed - indexed for MEDLINE]
Fri Sep 18, 2020 14:06
Related Articles [The morphometric parameters of projection triangle of visceral cranium and infratemporal fossa under various degree of integrity of upper dentition]. Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med. 2020 May;28(3):471-475 Authors: Gayvoronsky IV, Gayvoronskaya MG, Tcimbalistov AV, Ponomarev AA Abstract In order to study the change in the morphometric parameters of projection triangles of the facial skull during tooth loss...
Fri Sep 18, 2020 14:06
Related Articles [Neurofibromatosis type Ⅰwith parapharyngeal space invasion: report of one case]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Aug;34(8):758-760 Authors: Hu Y, Chen K, Tang M, Ren F, Cheng L, Shi Y, Chen Y, Wang L Abstract We described a 56-year-old male who was admitted to the hospital due to no sweat on the right side of face for 4 years, and paraesthesia pharynges for 1 month. The physical examination was carried...
Fri Sep 18, 2020 14:06
Related Articles Treatment of Frontal Sinus Osteomyelitis in the Age of Endoscopy. Am J Rhinol Allergy. 2020 Sep 16;:1945892420959587 Authors: Thompson HM, Tilak AM, Miller PL, Grayson JW, Cho DY, Woodworth BA Abstract OBJECTIVE: Frontal sinus osteomyelitis is a severe complication which can result from chronic rhinosinusitis, trauma, or as a complication of reconstruction or obliteration of the frontal sinus. The objective of the current study...
Fri Sep 18, 2020 14:06
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