IJMS, Vol. 21, Pages 4284: Hydrogen Sulfide Treatment Improves Post-Infarct Remodeling and Long-Term Cardiac Function in CSE Knockout and Wild-Type Mice International Journal of Molecular Sciences doi: 10.3390/ijms21124284 Authors: Ellmers Templeton Pilbrow Frampton Ishii Moore Bhatia Richards Cameron Hydrogen sulfide (H2S) is recognized as an endogenous gaseous signaling molecule generated by cystathionine γ-lyase (CSE) in cardiovascular tissues....
Tue Jun 16, 2020 03:00
IJMS, Vol. 21, Pages 4285: Regulation of Actin Filament Length by Muscle Isoforms of Tropomyosin and Cofilin International Journal of Molecular Sciences doi: 10.3390/ijms21124285 Authors: Katarzyna Robaszkiewicz Małgorzata Śliwinska Joanna Moraczewska In striated muscle the extent of the overlap between actin and myosin filaments contributes to the development of force. In slow twitch muscle fibers actin filaments are longer than in fast twitch fibers, but the mechanism which determines...
Tue Jun 16, 2020 03:00
IJMS, Vol. 21, Pages 4279: Early Cellular Responses Induced by Sedimentary Calcite-Processed Particles in Bright Yellow 2 Tobacco Cultured Cells International Journal of Molecular Sciences doi: 10.3390/ijms21124279 Authors: Daniel Tran Tingting Zhao Delphine Arbelet-Bonnin Takashi Kadono Patrice Meimoun Sylvie Cangémi Camille Noûs Tomonori Kawano Rafik Errakhi François Bouteau Calcite processed particles (CaPPs, Megagreen®) elaborated from sedimentary...
Tue Jun 16, 2020 03:00
IJMS, Vol. 21, Pages 4281: Targeting Histone Deacetylases to Modulate Graft-Versus-Host Disease and Graft-Versus-Leukemia International Journal of Molecular Sciences doi: 10.3390/ijms21124281 Authors: Sena Kim Srikanth Santhanam Sora Lim Jaebok Choi Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the main therapeutic strategy for patients with both malignant and nonmalignant disorders. The therapeutic benefits of allo-HSCT in malignant disorders are primarily...
Tue Jun 16, 2020 03:00
IJMS, Vol. 21, Pages 4282: How Do Post-Translational Modifications Influence the Pathomechanistic Landscape of Huntington’s Disease? A Comprehensive Review International Journal of Molecular Sciences doi: 10.3390/ijms21124282 Authors: Beata Lontay Andrea Kiss László Virág Krisztina Tar Huntington’s disease (HD) is an autosomal dominant inherited neurodegenerative disorder characterized by the loss of motor control and cognitive ability, which eventually leads to death....
Tue Jun 16, 2020 03:00
IJMS, Vol. 21, Pages 4280: 3-D Nucleus Architecture in Oat × Maize Addition Lines International Journal of Molecular Sciences doi: 10.3390/ijms21124280 Authors: Dominika Idziak-Helmcke Tomasz Warzecha Marta Sowa Marzena Warchoł Kinga Dziurka Ilona Czyczyło-Mysza Edyta Skrzypek The nucleus architecture of hybrid crop plants is not a well-researched topic, yet it can have important implications for their genetic stability and usefulness in the successful expression of...
Tue Jun 16, 2020 03:00
IJMS, Vol. 21, Pages 4275: Mutation of YL Results in a Yellow Leaf with Chloroplast RNA Editing Defect in Soybean International Journal of Molecular Sciences doi: 10.3390/ijms21124275 Authors: Xiaowei Zhu Yi Pan Zhi Liu Yucheng Liu Deyi Zhong Zongbiao Duan Zhixi Tian Baoge Zhu Guoan Zhou RNA editing plays a key role in organelle gene expression. Little is known about how RNA editing factors influence soybean plant development. Here, we report the isolation and...
Tue Jun 16, 2020 03:00
IJMS, Vol. 21, Pages 4276: Overexpression of Isoprene Synthase Affects ABA- and Drought-Related Gene Expression and Enhances Tolerance to Abiotic Stress International Journal of Molecular Sciences doi: 10.3390/ijms21124276 Authors: Xu Trainotti Li Varotto Isoprene is the most abundant single biogenic volatile compound emitted by plants. Despite the relevance of this molecule to plant abiotic resistance and its impact on global atmospheric chemistry, little is known about...
Tue Jun 16, 2020 03:00
IJMS, Vol. 21, Pages 4277: A Yeast-Based Model for Hereditary Motor and Sensory Neuropathies: A Simple System for Complex, Heterogeneous Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21124277 Authors: Rzepnikowska Kaminska Kabzińska Binięda Kochański Charcot–Marie–Tooth (CMT) disease encompasses a group of rare disorders that are characterized by similar clinical manifestations and a high genetic heterogeneity. Such excessive...
Tue Jun 16, 2020 03:00
IJMS, Vol. 21, Pages 4278: Effect of Berberine on Glycation, Aldose Reductase Activity, and Oxidative Stress in the Lenses of Streptozotocin-Induced Diabetic Rats In Vivo—A Preliminary Study International Journal of Molecular Sciences doi: 10.3390/ijms21124278 Authors: Zych Wojnar Kielanowska Folwarczna Kaczmarczyk-Sedlak Diabetes mellitus affects the eye lens, leading to cataract formation by glycation, osmotic stress, and oxidative stress. Berberine, an isoquinoline...
Tue Jun 16, 2020 03:00
IJMS, Vol. 21, Pages 4274: Therapeutic Potential of Tauroursodeoxycholic Acid for the Treatment of Osteoporosis International Journal of Molecular Sciences doi: 10.3390/ijms21124274 Authors: Ahn Kim Joshi Park Kyung Choi Sohn Sheen Shin Lee Han Tauroursodeoxycholic acid (TUDCA) is a US FDA-approved hydrophilic bile acid for the treatment of chronic cholestatic liver disease. In the present study, we investigate the effects of TUDCA on the proliferation...
Tue Jun 16, 2020 03:00
IJMS, Vol. 21, Pages 4273: Neuronal Reprogramming for Tissue Repair and Neuroregeneration International Journal of Molecular Sciences doi: 10.3390/ijms21124273 Authors: Liou Edwards Martin Wong Stem cell and cell reprogramming technology represent a rapidly growing field in regenerative medicine. A number of novel neural reprogramming methods have been established, using pluripotent stem cells (PSCs) or direct reprogramming, to efficiently derive specific neuronal cell types...
Tue Jun 16, 2020 03:00
IJMS, Vol. 21, Pages 4271: EMT and EndMT: Emerging Roles in Age-Related Macular Degeneration International Journal of Molecular Sciences doi: 10.3390/ijms21124271 Authors: Daisy Y. Shu Erik Butcher Magali Saint-Geniez Epithelial–mesenchymal transition (EMT) and endothelial–mesenchymal transition (EndMT) are physiological processes required for normal embryogenesis. However, these processes can be hijacked in pathological conditions to facilitate tissue fibrosis...
Tue Jun 16, 2020 03:00
IJMS, Vol. 21, Pages 4272: Wnt Signaling in Gynecologic Malignancies International Journal of Molecular Sciences doi: 10.3390/ijms21124272 Authors: Alexandra McMellen Elizabeth R. Woodruff Bradley R. Corr Benjamin G. Bitler Marisa R. Moroney Gynecologic malignancies, including ovarian cancer, endometrial cancer, and cervical cancer, affect hundreds of thousands of women worldwide every year. Wnt signaling, specifically Wnt/β-catenin signaling, has been found to play...
Tue Jun 16, 2020 03:00
IJMS, Vol. 21, Pages 4270: Computational Drug Repositioning for Chagas Disease Using Protein-Ligand Interaction Profiling International Journal of Molecular Sciences doi: 10.3390/ijms21124270 Authors: Alfredo Juárez-Saldivar Michael Schroeder Sebastian Salentin V. Joachim Haupt Emma Saavedra Citlali Vázquez Francisco Reyes-Espinosa Verónica Herrera-Mayorga Juan Carlos Villalobos-Rocha Carlos A. García-Pérez Nuria E. Campillo Gildardo Rivera Chagas disease,...
Tue Jun 16, 2020 03:00
IJMS, Vol. 21, Pages 4269: Sex Differences in Urate Handling International Journal of Molecular Sciences doi: 10.3390/ijms21124269 Authors: Victoria L. Halperin Kuhns Owen M. Woodward Hyperuricemia, or elevated serum urate, causes urate kidney stones and gout and also increases the incidence of many other conditions including renal disease, cardiovascular disease, and metabolic syndrome. As we gain mechanistic insight into how urate contributes to human disease, a clear sex difference...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1887: MiRNA Expression Profile in the Airways is Altered during Pulmonary Exacerbation in Children with Cystic Fibrosis—A Preliminary Report Journal of Clinical Medicine doi: 10.3390/jcm9061887 Authors: Zuzanna Stachowiak Irena Wojsyk-Banaszak Katarzyna Jończyk-Potoczna Beata Narożna Wojciech Langwiński Zdzisława Kycler Paulina Sobkowiak Anna Bręborowicz Aleksandra Szczepankiewicz MicroRNAs are small non-coding RNAs that regulate immune response...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1886: Cohen Syndrome Patient iPSC-Derived Neurospheres and Forebrain-Like Glutamatergic Neurons Reveal Reduced Proliferation of Neural Progenitor Cells and Altered Expression of Synapse Genes Journal of Clinical Medicine doi: 10.3390/jcm9061886 Authors: Lee Hwang Lee Yang Kwak Seo Ahn Lee Kim Lim Kaang Lee Lee Lee Cohen syndrome (CS), a rare autosomal recessive disorder, has been associated with genetic mutations...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1885: Vaccines and Therapies in Development for SARS-CoV-2 Infections Journal of Clinical Medicine doi: 10.3390/jcm9061885 Authors: David Wu Raghuram Koganti Upendra P. Lambe Tejabhiram Yadavalli Shyam S. Nandi Deepak Shukla The current COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. The virus causes severe respiratory symptoms which manifest disproportionately in the elderly. Currently, there are over 6.5 million cases and 380,000 deaths...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1883: Widespread Introduction of a High-Sensitivity Troponin Assay: Assessing the Impact on Patients and Health Services Journal of Clinical Medicine doi: 10.3390/jcm9061883 Authors: Jaimi H. Greenslade William Parsonage Laura Foran Louise McCormack Sarah Ashover Tanya Milburn Sara Berndt Martin Than David Brain Louise Cullen Adoption of High-sensitivity troponin (hs-cTn) assays by hospitals worldwide is increasing. We sought to determine...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1882: Transient and Persistent Gastric Microbiome: Adherence of Bacteria in Gastric Cancer and Dyspeptic Patient Biopsies after Washing Journal of Clinical Medicine doi: 10.3390/jcm9061882 Authors: Malene R. Spiegelhauer Juozas Kupcinskas Thor B. Johannesen Mindaugas Urba Jurgita Skieceviciene Laimas Jonaitis Tove H. Frandsen Limas Kupcinskas Kurt Fuursted Leif P. Andersen Helicobacter pylori is a common colonizer of the human stomach, and...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1877: Serum Metabolic Signatures of Chronic Limb-Threatening Ischemia in Patients with Peripheral Artery Disease Journal of Clinical Medicine doi: 10.3390/jcm9061877 Authors: Sandi M. Azab Abdelrahman Zamzam Muzammil H. Syed Rawand Abdin Mohammad Qadura Philip Britz-McKibbin Peripheral artery disease (PAD) is characterized by the atherosclerotic narrowing of lower limb vessels, leading to ischemic muscle pain in older persons. Some patients experience...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1881: Evaluation of Transcatheter Alcohol-Mediated Perivascular Renal Denervation to Treat Resistant Hypertension Journal of Clinical Medicine doi: 10.3390/jcm9061881 Authors: Adam Janas Marek Król Mariusz Hochuł Monika Jochymczyk Claudia Hayward-Costa Helen Parise Nicole Haratani Tim Fischell Wojciech Wojakowski Catheter-based renal denervation (RDN) has been investigated for hypertension (HTN) treatment with variable success. One of the novel...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1880: Self-Assessment of Competence and Referral Behavior for Musculoskeletal Injections among Dutch General Practitioners Journal of Clinical Medicine doi: 10.3390/jcm9061880 Authors: Emely Spruit Marianne F. Mol P. Koen Bos Sita M.A. Bierma-Zeinstra Patrick Krastman Jos Runhaar General practitioners (GPs) are qualified and trained to administer therapeutic musculoskeletal injections when indicated. However, it is unknown to what extend Dutch GPs...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1884: Complex Oncological Decision-Making Utilizing Fast-and-Frugal Trees in a Community Setting—Role of Academic and Hybrid Modeling Journal of Clinical Medicine doi: 10.3390/jcm9061884 Authors: Ravi Salgia Isa Mambetsariev Tingting Tan Amanda Schwer Daryl P. Pearlstein Hazem Chehabi Angel Baroz Jeremy Fricke Rebecca Pharaon Hannah Romo Thomas Waddington Razmig Babikian Linda Buck Prakash Kulkarni Mary Cianfrocca Benjamin Djulbegovic...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1879: Short-Period Temporal Dispersion Repolarization Markers Predict 30-Days Mortality in Decompensated Heart Failure Journal of Clinical Medicine doi: 10.3390/jcm9061879 Authors: Gianfranco Piccirillo Federica Moscucci Gaetano Bertani Ilaria Lospinuso Fabiola Mastropietri Marcella Fabietti Teresa Sabatino Giulia Zaccagnini Davide Crapanzano Ilaria Di Diego Andrea Corrao Pietro Rossi Damiano Magrì Background and Objectives: Electrocardiographic...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1878: Improving the Prognostic Performance of SUVmax in 18F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography Using Tumor-to-Liver and Tumor-to-Blood Standard Uptake Ratio for Locally Advanced Cervical Cancer Treated with Concurrent Chemoradiotherapy Journal of Clinical Medicine doi: 10.3390/jcm9061878 Authors: Gun Oh Chong Shin Young Jeong Yoon Hee Lee Shin-Hyung Park Hyun Jung Lee Sang-Woo Lee Dae Gy Hong Yoon Soon Lee Objective:...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1875: Sinus Rhythm Conduction Properties across Bachmann’s Bundle: Impact of Underlying Heart Disease and Atrial Fibrillation Journal of Clinical Medicine doi: 10.3390/jcm9061875 Authors: Christophe P. Teuwen Lisette J.M.E. van der Does Charles Kik Elisabeth M.J.P. Mouws Eva A.H. Lanters Paul Knops Yannick J.H.J. Taverne Ad J.J.C. Bogers Natasja M.S. de Groot Valvular heart disease (VHD) is a common risk factor for atrial fibrillation (AF)....
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1876: Temperament and Character Profile and Its Clinical Correlates in Male Patients with Dual Schizophrenia Journal of Clinical Medicine doi: 10.3390/jcm9061876 Authors: Laura Río-Martínez Julia E. Marquez-Arrico Gemma Prat Ana Adan Personality traits are relevant in understanding substance use disorders (SUD) and schizophrenia (SZ), but few works have also included patients with dual schizophrenia (SZ+) and personality traits. We explored personality profile...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1874: Parkinson’s Disease Multimodal Complex Treatment (PD-MCT): Analysis of Therapeutic Effects and Predictors for Improvement Journal of Clinical Medicine doi: 10.3390/jcm9061874 Authors: Elke Hartelt Raphael Scherbaum Manuel Kinkel Ralf Gold Siegfried Muhlack Lars Tönges Parkinson’s disease Multimodal Complex Treatment (PD-MCT) is a multidisciplinary inpatient treatment approach that has been demonstrated to improve motor function and quality...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1872: Is Heel Height Associated with Pain Exacerbations in Hip Osteoarthritis Patients?—Results from a Case-Crossover Study Journal of Clinical Medicine doi: 10.3390/jcm9061872 Authors: Kai Fu Ben R. Metcalf Kim L. Bennell Yuqing Zhang K. Douglas Gross Kathryn Mills Leticia A. Deveza Sarah R. Robbins David J. Hunter The etiology of osteoarthritis (OA) pain exacerbations is not well understood. The purpose of this study is to evaluate the association...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1873: Course of Adverse Events during Short Treatment Regimen in Patients with Rifampicin-Resistant Tuberculosis in Burundi Journal of Clinical Medicine doi: 10.3390/jcm9061873 Authors: François Ciza Tinne Gils Michel Sawadogo Tom Decroo Alberto Roggi Alberto Piubello Nimer Ortuño-Gutiérrez The introduction of the nine-month short-treatment regimen (STR) has drastically improved outcomes of rifampicin-resistant tuberculosis (RR-TB) treatment. Adverse...
Tue Jun 16, 2020 03:00
JCM, Vol. 9, Pages 1871: Performance Assessment of SARS-CoV-2 PCR Assays Developed by WHO Referral Laboratories Journal of Clinical Medicine doi: 10.3390/jcm9061871 Authors: Sibyle Etievant Antonin Bal Vanessa Escuret Karen Brengel-Pesce Maude Bouscambert Valérie Cheynet Laurence Generenaz Guy Oriol Gregory Destras Geneviève Billaud Laurence Josset Emilie Frobert Florence Morfin Alexandre Gaymard A reliable diagnostic assay is crucial to early detect...
Tue Jun 16, 2020 03:00
JFB, Vol. 11, Pages 42: Novel Coatings to Minimize Bacterial Adhesion and Promote Osteoblast Activity for Titanium Implants Journal of Functional Biomaterials doi: 10.3390/jfb11020042 Authors: Samira E. A. Camargo Tanaya Roy Patrick H. Carey IV Chaker Fares Fan Ren Arthur E. Clark Josephine F. Esquivel-Upshaw Titanium nitride (TiN) and silicon carbide (SiC) adhesion properties to biofilm and the proliferation of human osteoblasts were studied. Quaternized titanium nitride...
Tue Jun 16, 2020 03:00
JoF, Vol. 6, Pages 88: Aspergillus fumigatus Protease Alkaline Protease 1 (Alp1): A New Therapeutic Target for Fungal Asthma Journal of Fungi doi: 10.3390/jof6020088 Authors: Kirk M. Druey Morgan McCullough Ramaswamy Krishnan We review three recent findings that have fundamentally altered our understanding of causative mechanisms underlying fungal-related asthma. These mechanisms may be partially independent of host inflammatory processes but are strongly dependent upon the actions...
Tue Jun 16, 2020 03:00
JoF, Vol. 6, Pages 87: Ectomycorrhizal Fungal Inoculation of Sphaerosporella brunnea Significantly Increased Stem Biomass of Salix miyabeana and Decreased Lead, Tin, and Zinc, Soil Concentrations during the Phytoremediation of an Industrial Landfill Journal of Fungi doi: 10.3390/jof6020087 Authors: Dimitri J. Dagher Frédéric E. Pitre Mohamed Hijri Fast growing, high biomass willows (Salix sp.) have been extensively used for the phytoremediation of trace element-contaminated environments,...
Tue Jun 16, 2020 03:00
Medicina, Vol. 56, Pages 297: Residual Pulmonary Hypertension more than 20 Years after Repair of Shunt Lesions Medicina doi: 10.3390/medicina56060297 Authors: Jančauskaitė Rudienė Jakutis Geenen Roos-Hesselink Gumbienė Background and Objectives: After successful surgical repair of a congenital shunt lesion, pulmonary hypertension (PH) often disappears. However, PH can persist long-term after the closure. This study aimed to assess the prevalence of PH long-term after...
Tue Jun 16, 2020 03:00
Medicina, Vol. 56, Pages 296: Nipple–Areola Complex Reconstruction Medicina doi: 10.3390/medicina56060296 Authors: Andrea Sisti The reconstruction of the nipple–areola complex is the last step in the breast reconstruction process. Several techniques have been described over the years. The aim of this review is to provide clarity on the currently available reconstructive options.
Tue Jun 16, 2020 03:00
Medicines, Vol. 7, Pages 33: Oral Manifestations of Inflammatory Bowel Disease and the Role of Non-Invasive Surrogate Markers of Disease Activity Medicines doi: 10.3390/medicines7060033 Authors: Ribaldone Brigo Mangia Saracco Astegiano Pellicano Inflammatory bowel disease (IBD), which includes Crohn’s disease (CD) and ulcerative colitis (UC), can be associated with several extra-intestinal manifestations requiring a multidisciplinary management both in...
Tue Jun 16, 2020 03:00
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