[Objective and subjective assessment of a structured approach to computed tomography scans of the paranasal sinuses]. HNO. 2020 May 19;: Authors: Hildenbrand T, Krahe A, Ketterer MC, Offergeld C Abstract BACKGROUND: Sound knowledge of individual anatomy is essential in sinus surgery to prevent potentially serious complications. For the paranasal sinuses, computed tomography (CT) is the imaging technique of choice to preoperatively analyze individual...
Thu May 21, 2020 13:50
[Needs and burdens of palliative care patients with advanced and/or metastatic head and neck tumors]. HNO. 2020 May 19;: Authors: Roch C, Schendzielorz P, Scherzad A, van Oorschot B, Scheich M Abstract BACKGROUND: New therapeutic modalities enable good treatment options for patients with advanced and metastatic head and neck cancer. In this context, discussions about the end of life, advance care planning, and palliative concepts are often eclipsed....
Thu May 21, 2020 13:50
[Functional outcomes after surgical treatment of oropharyngeal carcinomas]. HNO. 2020 May 19;: Authors: Hofauer B, Mansour N, Becker C, Ketterer MC, Knopf A Abstract INTRODUCTION: The primary goal of surgical resection of oropharyngeal carcinoma (OPSCC) is an R0 resection. The extension of the primary tumor is decisive for selection of access route, which should be as circumscribed as possible but as radical as necessary. To date, there are no prospective...
Thu May 21, 2020 13:50
Extremely High Creatine Kinase Activity in Rhabdomyolysis without Acute Kidney Injury. Am J Case Rep. 2020 May 20;21:e924347 Authors: Hansrivijit P, Yarlagadda K, Puthenpura MM, Cunningham JM Abstract BACKGROUND Elevation of creatine kinase (CK) activity has been shown to be predictive of acute kidney injury (AKI) in rhabdomyolysis. Patients with extremely high CK activity with preserved renal function are uncommon. This report describes a case of non-traumatic...
Thu May 21, 2020 13:50
Radiation exposure to allied health personnel handling blood specimens from patients receiving radioactive iodine-131 and recombinant human TSH (Thyrogen®) stimulation. J Radiol Prot. 2020 May 20;: Authors: Tai S, Yang S, Tiew A, Wong YM, Ling SY, Tay YS, Loke K Abstract Background With increasing use of rhTSH stimulation protocol in I-131 treatment of thyroidectomized DTC, there is increasing concern regarding radiation safety during collection...
Thu May 21, 2020 13:48
Effect of Different 131I Dose Strategies for Treatment of Hyperthyroidism on Graves' Ophthalmopathy.
Effect of Different 131I Dose Strategies for Treatment of Hyperthyroidism on Graves' Ophthalmopathy. Clin Nucl Med. 2020 May 19;: Authors: Ariamanesh S, Ayati N, Mazloum Khorasani Z, Mousavi Z, Kiavash V, Kiamanesh Z, Zakavi SR Abstract PURPOSE: The study aims to define the effect of different dose strategies on ophthalmic complications in patients with Graves' disease (GD). METHODS: All the patients with GD and no or inactive ophthalmopathy...
Thu May 21, 2020 13:48
Synergistic interactions between Cajal bodies and the miRNA processing machinery. Mol Biol Cell. 2020 May 20;:mbcE20020144 Authors: Logan MK, McLaurin DM, Hebert MD Abstract Cajal bodies (CBs) are subnuclear domains involved in the formation of ribonucleoproteins (RNPs) including small nuclear RNPs (snRNPs). CBs associate with specific gene loci, which impacts expression and provides a platform for the biogenesis of the nascent transcripts emanating...
Thu May 21, 2020 13:47
Roles of Mso1 and the SM protein Sec1 in efficient vesicle fusion during fission yeast cytokinesis. Mol Biol Cell. 2020 May 20;:mbcE20010067 Authors: Gerien KS, Zhang S, Russell AC, Zhu YH, Purde V, Wu JQ Abstract Membrane trafficking during cytokinesis is essential for the delivery of membrane lipids and cargos to the division site. However, the molecular mechanisms are still incompletely understood. In this study, we demonstrate the importance of uncharacterized...
Thu May 21, 2020 13:47
Prostaglandins regulate invasive, collective border cell migration. Mol Biol Cell. 2020 May 20;:mbcE19100578 Authors: Fox EF, Lamb MC, Mellentine SQ, Tootle TL Abstract While prostaglandins (PGs), short-range lipid signals, regulate single cell migration, their roles in collective migration remain unclear. To address this, we use Drosophila border cell migration, an invasive, collective migration that occurs during Stage 9 of oogenesis. Pxt is the Drosophila...
Thu May 21, 2020 13:47
Flightless Anchors IQGAP1 and R-ras to Mediate Cell Extension Formation and Matrix Remodeling. Mol Biol Cell. 2020 May 20;:mbcE19100554 Authors: Arora PD, Nakajima K, Nanda A, Plaha A, Wilde A, Sacks DB, McCulloch CA Abstract Tractional remodeling of collagen fibrils by fibroblasts requires long cell extensions that mediate fibril alignment. The formation of these cell extensions involves flightless I (FliI), an actin binding protein that contains a...
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Nature Communications, Published online: 21 May 2020; doi:10.1038/s41467-020-15706-xOn the electrocardiogram, the PR interval reflects conduction from the atria to ventricles and also serves as risk indicator of cardiovascular morbidity and mortality. Here, the authors perform genome-wide meta-analyses for PR interval in multiple ancestries and identify 141 previously unreported genetic loci.
Thu May 21, 2020 03:00
Nature Communications, Published online: 21 May 2020; doi:10.1038/s41467-020-16161-4Living organisms, like fish and bacteria, frequently change their pattern as a group to cope with environment. Here, Bäuerle et al. reproduce this phenomenon using a synthetic system of controllably interactive colloids to show their collective motions that indicates being close to a critical point.
Thu May 21, 2020 03:00
Nature Communications, Published online: 21 May 2020; doi:10.1038/s41467-020-16255-zThe controllable synthesis of organometallic polymers that can be used in ultrahigh information storage and anti-counterfeiting security has been an unsolved challenge. Here, the authors show sequence-controlled electrosynthesis of organometallic polymers with exquisite insertion of multiple and distinct monomers.
Thu May 21, 2020 03:00
Nature Communications, Published online: 21 May 2020; doi:10.1038/s41467-020-16227-3Solar-driven CO2 reduction by abundant water to alcohols is hindered by the sluggish water oxidation reaction. Here, the authors demonstrate that the microwave-synthesized carbon-dots possess unique hole-accepting nature, allowing stoichiometric oxygen and methanol production from water and CO2 with nearly 100% selectivity to methanol.
Thu May 21, 2020 03:00
Nature Communications, Published online: 21 May 2020; doi:10.1038/s41467-020-16378-3Electronic Health Records (EHR) are subject to noise, biases and missing data. Here, the authors present MixEHR, a multi-view Bayesian framework related to collaborative filtering and latent topic models for EHR data integration and modeling.
Thu May 21, 2020 03:00
Nature Communications, Published online: 21 May 2020; doi:10.1038/s41467-020-16345-yDisease stress-induced cardiac hypertrophy is a major mechanism of pathological cardiac remodeling. Here, the authors unveil a previously unrecognized role of a FoxO1–Dio2 signaling axis in maladaptive, afterload-induced cardiac hypertrophy and intracellular thyroid hormone homeostasis.
Thu May 21, 2020 03:00
Nature Communications, Published online: 21 May 2020; doi:10.1038/s41467-020-16286-6Density-dependence is rarely accounted for in plant-plant facilitation studies. Here the authors develop a framework that incorporates density-dependence in the stress-gradient hypothesis, and test it first through modeling and then empirically on Arabidopsis thaliana along salt stress gradients.
Thu May 21, 2020 03:00
Nature Communications, Published online: 21 May 2020; doi:10.1038/s41467-020-15984-5Independently measuring the tidal deformability and the fundamental oscillation mode (fmode) frequency enables tests of gravity and the nature of compact binaries. Here, the authors constrain the f-mode frequencies of the companions of GW170817 from direct measurements, demonstrating gravitational wave asteroseismology with binary inspiral signals alone.
Thu May 21, 2020 03:00
Pheochromocytoma and Paraganglioma in Children and Adolescents: Experience of the French Society of Pediatric Oncology (SFCE). J Endocr Soc. 2020 May 01;4(5):bvaa039 Authors: de Tersant M, Généré L, Freyçon C, Villebasse S, Abbas R, Barlier A, Bodet D, Corradini N, Defachelles AS, Entz-Werle N, Fouquet C, Galmiche L, Gandemer V, Lacour B, Mansuy L, Orbach D, Pluchart C, Réguerre Y, Rigaud C, Sarnacki S, Sirvent N, Stephan JL, Thebaud E, Gimenez-Roqueplo AP, Brugières...
Thu May 21, 2020 13:44
Serous Microcystic Cystadenocarcinoma of the Pancreas with Synchronous Liver Metastases: Clinical Characteristics and Management. Cureus. 2020 Apr 17;12(4):e7707 Authors: Massaras D, Pantiora EV, Koutalas J, Primetis EC, Fragulidis GP Abstract Serous cystadenocarcinoma of the pancreas is a rare but well-established entity. The origin and evolution of this disorder remain unclear, but even metastatic cases have an excellent prognosis. These tumors are...
Thu May 21, 2020 13:44
Breath Analysis for Early Detection of Malignant Pleural Mesothelioma: Volatile Organic Compounds (VOCs) Determination and Possible Biochemical Pathways. Cancers (Basel). 2020 May 16;12(5): Authors: Di Gilio A, Catino A, Lombardi A, Palmisani J, Facchini L, Mongelli T, Varesano N, Bellotti R, Galetta D, de Gennaro G, Tangaro S Abstract Malignant pleural mesothelioma (MPM) is a rare neoplasm, mainly caused by asbestos exposure, with a high mortality rate....
Thu May 21, 2020 13:44
The Neuroendocrine Neoplasms of the Digestive Tract: Diagnosis, Treatment and Nutrition. Nutrients. 2020 May 15;12(5): Authors: Pobłocki J, Jasińska A, Syrenicz A, Andrysiak-Mamos E, Szczuko M Abstract Nuroendocrine neoplasms (NENs) are a group of rare neoplasms originating from dispersed neuroendocrine cells, mainly of the digestive and respiratory tract, showing characteristic histology and immunoprofile contributing to classification of NENs. Some...
Thu May 21, 2020 13:44
Related ArticlesSuccessful fourth line treatment of a relapse patient with chronic hepatitis C virus infection genotype 3a using sofosbuvir, glecaprevir/pibrentasvir, and ribavirin: a case report. Z Gastroenterol. 2020 May;58(5):451-455 Authors: Bernhard B, Stickel F Abstract BACKGROUND: Relapses after therapy with direct-acting antiviral agents (DAA) in chronic hepatitis C virus (HCV) infections are rare due to high efficacy of interferon-free therapy...
Thu May 21, 2020 13:44
Related ArticlesInterdisciplinary rehabilitation of a primary intraosseous carcinoma including orthodontic archform management. Quintessence Int. 2020;51(6):464-472 Authors: Rasmussen CM, Lee SKY, Arce K, Salinas TJ Abstract Squamous cell carcinomas arising from keratocystic odontogentic tumors are a rare phenomenon in head and neck cancer, accounting for only 1.45% of oral squamous cell carcinomas, and are classified as primary intraosseous carninomas....
Thu May 21, 2020 13:44
Related ArticlesIncreased FDG Uptake on Juxtaglomerular Cell Tumor in the Left Kidney Mimicking Malignancy. Clin Nucl Med. 2020 Mar;45(3):252-254 Authors: Jiang Y, Hou G, Zhu Z, Zang J, Cheng W Abstract Juxtaglomerular cell tumor is a rare and benign tumor arising from the juxtaglomerular apparatus that overproduces renin, resulting in secondary hypertension. A 29-year-old woman was incidentally found to have a left renal mass by ultrasonography in...
Thu May 21, 2020 13:44
Related ArticlesSolitary Cerebellar Metastasis of Ovarian Cancer Detected by FDG PET/CT. Clin Nucl Med. 2020 Mar;45(3):230-231 Authors: Hou G, Jiang Y, Cheng X Abstract Ovarian cancer with solitary metastasis to the cerebellum is very rare. We presented a 58-year-old woman complaining of headaches 9 months after debulking surgery and chemotherapy due to ovarian cancer. The serum CA125 level was elevated. FDG PET/CT was then recommended to identify potential...
Thu May 21, 2020 13:44
Related ArticlesMagnetic Resonance Imaging Findings of Biliary Adenofibroma. Korean J Gastroenterol. 2019 Dec 25;74(6):356-361 Authors: Lee S, Kim KW, Jeong WK, Yu E, Jang KT Abstract Biliary adenofibroma is a rare tumor with a bile duct origin characterized by a complex tubulocystic non-mucin secreting biliary epithelium with abundant fibrous stroma. The MRI features of biliary adenofibroma are not well established. The authors encountered two patients...
Thu May 21, 2020 13:44
Related ArticlesPrimary Angiosarcoma of the Cervix: Case Report of a Rare Lesion. Int J Gynecol Pathol. 2020 Jan;39(1):97-102 Authors: Shah VI, Rowlands GL, Thompson IW, Sumathi VP, McCluggage WG Abstract Angiosarcomas of the female genital tract are rare and primary angiosarcoma of the cervix is extremely rare with only one prior case report. We report a case of a primary cervical angiosarcoma in a 43-yr-old woman who presented with heavy vaginal bleeding....
Thu May 21, 2020 13:44
Related ArticlesMalignant Lymphoma of the Ovary: A Diagnostic Pitfall of Intraoperative Consultation. Int J Gynecol Pathol. 2020 Jan;39(1):79-83 Authors: Iizuka N, Ikura Y, Fukuoka Y, Shibata T, Okamoto M, Kamiya A, Oishi T, Kotsuji F, Iwai Y Abstract Primary ovarian lymphomas are rare, but can potentially evoke diagnostic problems. We present a case of ovarian lymphoma, in which an ambiguous intraoperative pathologic report led to overtreatment (unnecessary...
Thu May 21, 2020 13:44
Related ArticlesWilms Tumor of the Ovary: Review of the Literature and Report of 2 Cases. Int J Gynecol Pathol. 2020 Jan;39(1):72-78 Authors: Turashvili G, Fix DJ, Soslow RA, Park KJ Abstract Primary extrarenal Wilms tumor of the gynecologic tract is extremely rare with scattered case reports occurring in the ovary, uterine corpus and cervix. Only 9 cases of primary ovarian Wilms tumor have been reported to date. Here, we provide an extensive literature...
Thu May 21, 2020 13:44
Related Articles[Cutaneous metastasis of prostate adenocarcinoma: a case report]. Rev Peru Med Exp Salud Publica. 2019 Jul-Sep;36(3):525-529 Authors: Chapoñan-Relaiza M, Deza HM, García J, Delgado V Abstract Cutaneous metastases are very rare events and are related to a distant tumor invasion. Prostate metastases have a 1% appearance rate; the most common locations include the genital or suprapubic region and are very rarely located at a distance. We...
Thu May 21, 2020 13:44
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