Antibiotics, Vol. 9, Pages 315: Opportunities and Challenges for Improving Anti-Microbial Stewardship in Low- and Middle-Income Countries; Lessons Learnt from the Maternal Sepsis Intervention in Western Uganda Antibiotics doi: 10.3390/antibiotics9060315 Authors: Ackers Ackers-Johnson Seekles Odur Opio This paper presents findings from an action-research intervention designed to identify ways of improving antimicrobial stewardship in a Ugandan Regional Referral Hospital....
Tue Jun 09, 2020 03:00
Antibiotics, Vol. 9, Pages 314: Activity of Specialized Biomolecules against Gram-Positive and Gram-Negative Bacteria Antibiotics doi: 10.3390/antibiotics9060314 Authors: Tavares Antunes Padrão Ribeiro Zille Amorim Ferreira Felgueiras The increased resistance of bacteria against conventional pharmaceutical solutions, the antibiotics, has raised serious health concerns. This has stimulated interest in the development of bio-based therapeutics with limited...
Tue Jun 09, 2020 03:00
Antibiotics, Vol. 9, Pages 313: Tiamulin-Resistant Mutants of the Thermophilic Bacterium Thermus thermophilus Antibiotics doi: 10.3390/antibiotics9060313 Authors: Erin E. Killeavy Gerwald Jogl Steven T. Gregory Tiamulin is a semisynthetic pleuromutilin antibiotic that binds to the 50S ribosomal subunit A site and whose (((2-diethylamino)ethyl)thio)-acetic acid tail extends into the P site to interfere with peptide bond formation. We have isolated spontaneous tiamulin-resistant...
Tue Jun 09, 2020 03:00
Antibiotics, Vol. 9, Pages 312: Candidiasis and Mechanisms of Antifungal Resistance Antibiotics doi: 10.3390/antibiotics9060312 Authors: Somanon Bhattacharya Sutthichai Sae-Tia Bettina C. Fries Candidiasis can be present as a cutaneous, mucosal or deep-seated organ infection, which is caused by more than 20 types of Candida sp., with C. albicans being the most common. These are pathogenic yeast and are usually present in the normal microbiome. High-risk individuals are patients...
Tue Jun 09, 2020 03:00
Antioxidants, Vol. 9, Pages 508: Erratum: Abidar, S.; et al. The Aqueous Extract from Ceratonia siliqua Leaves Protects against 6-Hydroxydopamine in Zebrafish: Understanding the Underlying Mechanism. Antioxidants 2020, 9, 304 Antioxidants doi: 10.3390/antiox9060508 Authors: Sara Abidar Razvan Stefan Boiangiu Gabriela Dumitru Elena Todirascu-Ciornea Amina Amakran Oana Cioanca Lucian Hritcu Mohamed Nhiri The authors wish to make the following correction to their paper...
Tue Jun 09, 2020 03:00
Antioxidants, Vol. 9, Pages 504: Superior Antioxidant Capacity of Berberis iliensis—HPLC-Q-TOF-MS Based Phytochemical Studies and Spectrophotometric Determinations Antioxidants doi: 10.3390/antiox9060504 Authors: Saniia Abdykerimova Zuriyadda Sakipova Sylwia Nakonieczna Wojciech Koch Anna Biernasiuk Aneta Grabarska Anna Malm Kaldanay Kozhanova Wirginia Kukula-Koch The aim of the present study was to determine the composition, antiradical and antimicrobial activity...
Tue Jun 09, 2020 03:00
Antioxidants, Vol. 9, Pages 506: Polymyxins–Curcumin Combination Antimicrobial Therapy: Safety Implications and Efficacy for Infection Treatment Antioxidants doi: 10.3390/antiox9060506 Authors: Dai Wang Sharma Shen Velkov Xiao The emergence of antimicrobial resistance in Gram-negative bacteria poses a huge health challenge. The therapeutic use of polymyxins (i.e., colistin and polymyxin B) is commonplace due to high efficacy and limiting treatment options for multidrug-resistant...
Tue Jun 09, 2020 03:00
Antioxidants, Vol. 9, Pages 507: Baicalein Inhibits Benzo[a]pyrene-Induced Toxic Response by Downregulating Src Phosphorylation and by Upregulating NRF2-HMOX1 System Antioxidants doi: 10.3390/antiox9060507 Authors: Tanaka Ito Tsuji Furue Benzo[a]pyrene (BaP), a major environmental pollutant, activates aryl hydrocarbon receptor (AHR), induces its cytoplasmic-to-nuclear translocation and upregulates the production of cytochrome P450 1A1 (CYP1A1), a xenobiotic metabolizing...
Tue Jun 09, 2020 03:00
Antioxidants, Vol. 9, Pages 503: Structure-Dependent Effects of Bisphosphonates on Inflammatory Responses in Cultured Neonatal Mouse Calvaria Antioxidants doi: 10.3390/antiox9060503 Authors: Keiko Suzuki Sadaaki Takeyama Shinobu Murakami Masahiro Nagaoka Mirei Chiba Kaoru Igarashi Hisashi Shinoda Bisphosphonates (BPs) are classified into two groups, according to their side chain structures, as nitrogen-containing BPs (NBPs) and non-nitrogen-containing BPs (non-NBPs)....
Tue Jun 09, 2020 03:00
Antioxidants, Vol. 9, Pages 505: Carotenoids and Chlorophylls as Antioxidants Antioxidants doi: 10.3390/antiox9060505 Authors: Pérez-Gálvez Viera Roca Chlorophylls and carotenoids are natural pigments that are present in our daily diet, especially with the increasing tendency towards more natural and healthy behaviors among consumers. As disturbed antioxidant homeostasis capacities seem to be implicated in the progress of different pathologies, the antioxidant properties of...
Tue Jun 09, 2020 03:00
Atmosphere, Vol. 11, Pages 612: Cold Waves in East China and Their Response to Two Types of Arctic Amplification Atmosphere doi: 10.3390/atmos11060612 Authors: Wei Tao Yuman Ni Chuhan Lu Cold waves occur frequently in East China, with their cold air source in the Arctic. Changes in the Arctic are often linked with Arctic amplification. The circulation anomaly associated with Arctic amplification is often represented by Arctic Oscillation (AO). In recent years, storms have frequently...
Tue Jun 09, 2020 03:00
Atmosphere, Vol. 11, Pages 611: Topoclimatic Zoning and Representative Areas as Determined by an Automatic Weather Station (AWS) Network in the Atacama Region, Chile Atmosphere doi: 10.3390/atmos11060611 Authors: Cortez Padilla Herrera Uribe Paneque Climate information is crucial to the management and profitability of key development sectors involving agriculture, hydrologic resources, natural hazards, and energy. Climate knowledge, real-time weather information, and...
Tue Jun 09, 2020 03:00
Atmosphere, Vol. 11, Pages 608: Assessment of Total Climate Change Impacts on the Agricultural Sector of Cyprus Atmosphere doi: 10.3390/atmos11060608 Authors: Christina Papadaskalopoulou Marco Moriondo Ioannis Lemesios Anna Karali Angeliki Konsta Camilla Dibari Lorenzo Brilli Konstantinos V. Varotsos Andreas Stylianou Maria Loizidou Marinos Markou Christos Giannakopoulos In this paper, the results of a climate change impact and vulnerability assessment...
Tue Jun 09, 2020 03:00
Atmosphere, Vol. 11, Pages 607: Effectivity and Cost Efficiency of a Tax on Nitrogen Fertilizer to Reduce GHG Emissions from Agriculture Atmosphere doi: 10.3390/atmos11060607 Authors: Andreas Meyer-Aurich Yusuf Nadi Karatay Ausra Nausediene Dieter Kirschke The use of nitrogen (N) fertilizer substantially contributes to greenhouse gas (GHG) emissions due to N2O emissions from agricultural soils and energy-intensive fertilizer manufacturing. Thus, a reduction of mineral N fertilizer...
Tue Jun 09, 2020 03:00
Atmosphere, Vol. 11, Pages 610: Moisture Source Tagging Confirming the Polar Amplification Effect in Amplifying the Temperature-δ18O Temporal Slope Since the LGM Atmosphere doi: 10.3390/atmos11060610 Authors: Guan Liu Chen Stable water isotopologues in paleoclimate archives (δ18O) have been widely used as an indicator to derive past climate variations. The modern observed spatial δ18O-temperature relation in the middle and high latitudes has been used to...
Tue Jun 09, 2020 03:00
Atmosphere, Vol. 11, Pages 609: Relationship of Weather Types on the Seasonal and Spatial Variability of Rainfall, Runoff, and Sediment Yield in the Western Mediterranean Basin Atmosphere doi: 10.3390/atmos11060609 Authors: D. Peña-Angulo E. Nadal-Romero J.C. González-Hidalgo J. Albaladejo V. Andreu H. Barhi S. Bernal M. Biddoccu R. Bienes J. Campo M.A. Campo-Bescós A. Canatário-Duarte Y. Cantón J. Casali V. Castillo E. Cavallo A. Cerdà P....
Tue Jun 09, 2020 03:00
Atmosphere, Vol. 11, Pages 583: Using Low-Cost Measurement Systems to Investigate Air Quality: A Case Study in Palapye, Botswana Atmosphere doi: 10.3390/atmos11060583 Authors: William Lassman Jeffrey R. Pierce Evelyn J. Bangs Amy P. Sullivan Bonne Ford Gizaw Mengistu Tsidu James P. Sherman Jeffrey L. Collett Solomon Bililign Exposure to particulate air pollution is a major cause of mortality and morbidity worldwide. In developing countries, the combustion of solid...
Tue Jun 09, 2020 03:00
Atmosphere, Vol. 11, Pages 606: Indication of the Two Linear Correlation Methods Between Vegetation Index and Climatic Factors: An Example in the Three River-Headwater Region of China During 2000–2016 Atmosphere doi: 10.3390/atmos11060606 Authors: Jiaxin Xu Shibo Fang Xuan Li Zichun Jiang The within-growing-season correlations (WGSC) and the inter-growing-season correlations (IGSC) are widely used linear correlation analysis methods between vegetation index and climatic factors...
Tue Jun 09, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 97: Appraisal of Motor Skills in a Sample of Students within the Moldavian Area Behavioral Sciences doi: 10.3390/bs10060097 Authors: Ionut Onose Beatrice Aurelia Abalasei Raluca Mihaela Onose Adriana Albu The selection of children for training in a certain sports branch should be based on the assessment of their physical development and their motor skills. The aim of the study: the evaluation of the students’ motor skills in relation...
Tue Jun 09, 2020 03:00
Beverages, Vol. 6, Pages 39: A Digital Approach to Evaluate the Effect of Berry Cell Death on Pinot Noir Wines’ Quality Traits and Sensory Profiles Using Non-Destructive Near-Infrared Spectroscopy Beverages doi: 10.3390/beverages6020039 Authors: Sigfredo Fuentes Eden Tongson Juesheng Chen Claudia Gonzalez Viejo Berry cell death (BCD) is linked to the development of flavors and aromas in berries and wine. The BCD pattern and rate within a growing season start at around 90–100...
Tue Jun 09, 2020 03:00
Biomolecules, Vol. 10, Pages 885: Marine-Derived Surface Active Agents: Health-Promoting Properties and Blue Biotechnology-Based Applications Biomolecules doi: 10.3390/biom10060885 Authors: Ioannis Anestopoulos Despina-Evgenia Kiousi Ariel Klavaris Monica Maijo Annabel Serpico Alba Suarez Guiomar Sanchez Karina Salek Stylliani A. Chasapi Aikaterini A. Zompra Alex Galanis Georgios A. Spyroulias Lourdes Gombau Stephen R. Euston Aglaia Pappa Mihalis...
Tue Jun 09, 2020 03:00
Biomolecules, Vol. 10, Pages 886: Leptin and Notch Signaling Cooperate in Sustaining Glioblastoma Multiforme Progression Biomolecules doi: 10.3390/biom10060886 Authors: Salvatore Panza Umberto Russo Francesca Giordano Antonella Leggio Ines Barone Daniela Bonofiglio Luca Gelsomino Rocco Malivindi Francesca Luisa Conforti Giuseppina Daniela Naimo Cinzia Giordano Stefania Catalano Sebastiano Andò Glioblastoma multiforme (GBM) is the most malignant form...
Tue Jun 09, 2020 03:00
Biomolecules, Vol. 10, Pages 884: The Mutant p53-Driven Secretome Has Oncogenic Functions in Pancreatic Ductal Adenocarcinoma Cells Biomolecules doi: 10.3390/biom10060884 Authors: Giovanna Butera Jessica Brandi Chiara Cavallini Aldo Scarpa Rita T. Lawlor Maria Teresa Scupoli Emílio Marengo Daniela Cecconi Marcello Manfredi Massimo Donadelli The cancer secretome is a rich repository of useful information for both cancer biology and clinical oncology. A better...
Tue Jun 09, 2020 03:00
Biosensors, Vol. 10, Pages 62: Study of the Dielectric Properties of Artificial Sweat Mixtures at Microwave Frequencies Biosensors doi: 10.3390/bios10060062 Authors: Angie R. Eldamak Sarah Thorson Elise C. Fear Analysis of sweat is of interest for a variety of diagnosis and monitoring applications in healthcare. In this work, detailed measurements of the dielectric properties of solutions representing the major components of sweat are presented. The measurements include aqueous...
Tue Jun 09, 2020 03:00
Biosensors, Vol. 10, Pages 61: A Deformation of a Mercury Droplet under Acceleration in an Annular Groove Biosensors doi: 10.3390/bios10060061 Authors: HanYang Xu Yulong Zhao Kai Zhang Zixi Wang Kyle Jiang Microelectromechanical system (MEMS) liquid sensors may be used under large acceleration conditions. It is important to understand the deformation of the liquid droplets under acceleration for the design and applications of MEMS liquid sensors, as this will affect the performance...
Tue Jun 09, 2020 03:00
Brain Sciences, Vol. 10, Pages 360: Migraine Frequency Decrease Following Prolonged Medical Cannabis Treatment: A Cross-Sectional Study Brain Sciences doi: 10.3390/brainsci10060360 Authors: Aviram Vysotski Berman Lewitus Eisenberg Meiri Background: Medical cannabis (MC) treatment for migraine is practically emerging, although sufficient clinical data are not available for this indication. This cross-sectional questionnaire-based study aimed to investigate the associations...
Tue Jun 09, 2020 03:00
Brain Sciences, Vol. 10, Pages 359: Neuroanatomical Changes in Leber’s Hereditary Optic Neuropathy: Clinical Application of 7T MRI Submillimeter Morphometry Brain Sciences doi: 10.3390/brainsci10060359 Authors: Kamil Jonak Paweł Krukow Mark Symms Ryszard Maciejewski Cezary Grochowski Leber’s hereditary optic neuropathy (LHON) is one of the mitochondrial diseases that causes loss of central vision, progressive impairment and subsequent degeneration of retinal ganglion...
Tue Jun 09, 2020 03:00
Brain Sciences, Vol. 10, Pages 357: The Iatrogenic Development of an Anterior Cerebral Artery Pseudoaneurysm during Lamina Terminalis Fenestration–Genesis, Diagnosis and Therapy: Lessons Learned Brain Sciences doi: 10.3390/brainsci10060357 Authors: Bartoš Robert Lodin Jan Hejčl Aleš Sameš Martin Cihlář Filip Intracranial pseudoaneurysms (PSA) are scarcely presented in the literature. We describe the case of an intracranial PSA on the right anterior cerebral artery, which...
Tue Jun 09, 2020 03:00
Brain Sciences, Vol. 10, Pages 358: Stress-Induced Increase in Cortisol Negatively Affects the Consolidation of Contextual Elements of Episodic Memories Brain Sciences doi: 10.3390/brainsci10060358 Authors: Matthew Sabia Almut Hupbach Stress can modulate episodic memory in various ways. The present study asks how post-encoding stress affects visual context memory. Participants encoded object images centrally positioned on background scenes. After encoding, they were either exposed...
Tue Jun 09, 2020 03:00
Cancers, Vol. 12, Pages 1511: Current Landscape of Breast Cancer Imaging and Potential Quantitative Imaging Markers of Response in ER-Positive Breast Cancers Treated with Neoadjuvant Therapy Cancers doi: 10.3390/cancers12061511 Authors: Ella F. Jones Deep K. Hathi Rita Freimanis Rita A. Mukhtar A. Jo Chien Laura J. Esserman Laura J. van’t van’t Veer Bonnie N. Joe Nola M. Hylton In recent years, neoadjuvant treatment trials have shown that breast cancer subtypes...
Tue Jun 09, 2020 03:00
Cancers, Vol. 12, Pages 1510: Serum Type XIX Collagen is Significantly Elevated in Non-Small Cell Lung Cancer: A Preliminary Study on Biomarker Potential Cancers doi: 10.3390/cancers12061510 Authors: Jeppe Thorlacius-Ussing Tina Manon-Jensen Shu Sun Diana J. Leeming Jannie M. Sand Morten Karsdal Nicholas Willumsen Type XIX collagen is a poorly characterized collagen associated with the basement membrane. It is abnormally regulated during breast cancer progression and...
Tue Jun 09, 2020 03:00
Cancers, Vol. 12, Pages 1509: Complementary Use of Carbohydrate Antigens Lewis a, Lewis b, and Sialyl-Lewis a (CA19.9 Epitope) in Gastrointestinal Cancers: Biological Rationale Towards A Personalized Clinical Application Cancers doi: 10.3390/cancers12061509 Authors: Rossella Indellicato Aida Zulueta Anna Caretti Marco Trinchera Carbohydrate antigen 19.9 (CA19.9) is used as a tumor marker for clinical and research purposes assuming that it is abundantly produced by gastrointestinal...
Tue Jun 09, 2020 03:00
Cancers, Vol. 12, Pages 1507: Small Non-Coding RNA Profiling in Plasma Extracellular Vesicles of Bladder Cancer Patients by Next-Generation Sequencing: Expression Levels of miR-126-3p and piR-5936 Increase with Higher Histologic Grades Cancers doi: 10.3390/cancers12061507 Authors: Alexandru A. Sabo Giovanni Birolo Alessio Naccarati Mihnea P. Dragomir Serena Aneli Alessandra Allione Marco Oderda Marco Allasia Paolo Gontero Carlotta Sacerdote Paolo Vineis Giuseppe...
Tue Jun 09, 2020 03:00
Cancers, Vol. 12, Pages 1508: Development of Folate Receptor−Targeted PET Radiopharmaceuticals for Tumor Imaging—A Bench-to-Bedside Journey Cancers doi: 10.3390/cancers12061508 Authors: Silvan D. Boss Simon Mensah Ametamey The folate receptor-α (FR-α) is overexpressed in many epithelial cancers, including ovary, uterus, kidneys, breast, lung, colon and prostate carcinomas, but shows limited expression in normal tissues such as kidneys, salivary glands, choroid...
Tue Jun 09, 2020 03:00
Cancers, Vol. 12, Pages 1512: Prognostic Impact of Pretherapeutic FDG-PET in Localized Anal Cancer Cancers doi: 10.3390/cancers12061512 Authors: Maelle Le Thiec Aude Testard Ludovic Ferrer Camille Guillerminet Olivier Morel Bruno Maucherat Daniela Rusu Sylvie Girault Marie Lacombe Hadji Hamidou Véronique Meyer Emmanuel Rio Sandrine Hiret Françoise Kraeber-Bodéré Loïc Campion Caroline Rousseau Due to the heterogeneity of tumour mass segmentation...
Tue Jun 09, 2020 03:00
Cancers, Vol. 12, Pages 1503: Identifying and Overcoming Mechanisms of PARP Inhibitor Resistance in Homologous Recombination Repair-Deficient and Repair-Proficient High Grade Serous Ovarian Cancer Cells Cancers doi: 10.3390/cancers12061503 Authors: Miriam K. Gomez Giuditta Illuzzi Carlota Colomer Michael Churchman Robert L. Hollis Mark J. O’Connor Charlie Gourley Elisabetta Leo David W. Melton High grade serous ovarian cancer (HGSOC) is a major cause of female...
Tue Jun 09, 2020 03:00
Cancers, Vol. 12, Pages 1505: Capture-based Next-Generation Sequencing Improves the Identification of Immunoglobulin/T-Cell Receptor Clonal Markers and Gene Mutations in Adult Acute Lymphoblastic Leukemia Patients Lacking Molecular Probes Cancers doi: 10.3390/cancers12061505 Authors: Roberta Cavagna Marie L. Guinea Guinea Montalvo Manuela Tosi Michela Paris Chiara Pavoni Tamara Intermesoli Renato Bassan Andrea Mosca Alessandro Rambaldi Orietta Spinelli The...
Tue Jun 09, 2020 03:00
Cancers, Vol. 12, Pages 1504: Oncolytic Adenoviruses: Strategies for Improved Targeting and Specificity Cancers doi: 10.3390/cancers12061504 Authors: Hajeri Sharma Yamamoto Cancer is a major health problem. Most of the treatments exhibit systemic toxicity, as they are not targeted or specific to cancerous cells and tumors. Adenoviruses are very promising gene delivery vectors and have immense potential to deliver targeted therapy. Here, we review a wide range of strategies that...
Tue Jun 09, 2020 03:00
Cancers, Vol. 12, Pages 1506: Association of Genetic Variants in ANGPT/TEK and VEGF/VEGFR with Progression and Survival in Head and Neck Squamous Cell Carcinoma Treated with Radiotherapy or Radiochemotherapy Cancers doi: 10.3390/cancers12061506 Authors: Dorota Butkiewicz Agnieszka Gdowicz-Kłosok Małgorzata Krześniak Tomasz Rutkowski Aleksandra Krzywon Alexander Jorge Cortez Iwona Domińczyk Krzysztof Składowski Angiogenesis is essential for growth, progression, and...
Tue Jun 09, 2020 03:00
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