Related ArticlesOverall survival and PD-L1 expression in patients with recurrent or metastatic head and neck cancer treated with nivolumab. Auris Nasus Larynx. 2020 Jun 04;: Authors: Okamoto I, Sato H, Tsukahara K Abstract OBJECTIVE: Our facility measures programmed cell death ligand 1 (PD-L1) expression in all patients before administering nivolumab. The aim of the present study is to clarify the association between overall survival (OS) and PD-L1 expression....
Hypofractionated radiotherapy and surgery compared to standard radiotherapy in early glottic cancer.
Related ArticlesHypofractionated radiotherapy and surgery compared to standard radiotherapy in early glottic cancer. Am J Otolaryngol. 2020 May 15;41(5):102544 Authors: Kim KN, Dyer MA, Qureshi MM, Shah NK, Grillone GA, Faden DL, Jalisi SM, Truong MT Abstract PURPOSE: Early-stage glottic laryngeal cancer is treated with surgery or radiotherapy (RT), but limited randomized data exists to support one modality over the other. This study evaluates survival...
Related ArticlesWideband acoustic immitance - Absorbance measurements in ears after stapes surgery. Auris Nasus Larynx. 2020 Jun 04;: Authors: Niemczyk E, Lachowska M, Tataj E, Kurczak K, Niemczyk K Abstract OBJECTIVES: The study aimed to thoroughly assess absorbance in ears after stapes surgery (stapedotomy/stapedectomy) and how stapes surgery affects wideband acoustic immittance (WAI) metrics. METHODS: Eighty-three otosclerotic ears were analyzed...
Related ArticlesResection of a desmoid-type fibromatosis with a CTNNB1 p.S45P mutation using a cervico-thoracic approach: A case report and literature review. Auris Nasus Larynx. 2020 Jun 03;: Authors: Sato R, Bandoh N, Goto T, Uemura A, Inoue N, Otomo Y, Nakano H, Yamaguchi T, Kato Y, Nishihara H, Takei H, Harabuchi Y Abstract Desmoid-type fibromatosis (DF) is a rare, locally infiltrative, and fibroblastic proliferative disease. DF usually arises from...
Related ArticlesThe occasional bougie-assisted cricothyroidotomy. Can J Rural Med. 2020 Jan-Mar;25(1):41-48 Authors: Johnston TMC, Davis PJ PMID: 31854341 [PubMed - indexed for MEDLINE]
Related ArticlesHeat shock protein 70 is a positive regulator of airway inflammation and goblet cell hyperplasia in a mouse model of allergic airway inflammation. J Biol Chem. 2019 10 11;294(41):15082-15094 Authors: Yombo DJK, Mentink-Kane MM, Wilson MS, Wynn TA, Madala SK Abstract Heat shock proteins (Hsps) are highly conserved molecular chaperones that are ubiquitously expressed in all species to aid the solubilization of misfolded proteins, protein...
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Related ArticlesSuccessful Anti-TNF-Alpha Therapy for Crohn's Disease After Allogeneic Stem Cell Transplantation: A Case Report. Tohoku J Exp Med. 2020;251(2):81-85 Authors: Kamachi K, Ando T, Tsuruoka N, Hashiguchi M, Kidoguchi K, Kusaba K, Sano H, Sano H, Yamaguchi K, Nishioka A, Yoshimura M, Yokoo M, Kubota Y, Kojima K, Kimura S Abstract Graft-versus-host disease (GVHD) is a potentially life-threatening complication of allogeneic stem cell transplantation...
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Related ArticlesCryptococcosis in an HIV-negative, HCV positive, immunosenescent patient: a case report. New Microbiol. 2020 Jun;43(2):99-102 Authors: Colaneri M, Cavanna C, Mussa M, Morea A, Manciulli T, Brunetti E, Di Matteo A, Lallitto F Abstract Cryptococcus species is still a very common opportunistic infection in AIDS patients. However, it is increasingly responsible for disease in otherwise immunocompromised individuals, such as transplant...
Related ArticlesClinical Utility of Platelet Count for Screening of Malaria. New Microbiol. 2020 Apr;43(2):89-92 Authors: Leli C, Di Matteo L, Gotta F, Vay D, Cavallo V, Mazzeo R, Busso S, Carrabba L, Rocchetti A Abstract Light microscopy, immunochromatographic rapid diagnostic tests and molecular methods are widely used to diagnose malaria. The aim of this study was to find variables among commonly available urgent blood tests to identify patients...
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Related ArticlesCongenital nasal piriform aperture atresia: A case report and novel finding. Int J Pediatr Otorhinolaryngol. 2020 May 19;135:110124 Authors: Angulo C, Jayawardena ADL, Caruso PA, Ramos D, Bonilla JA, Zablah E, Hartnick CJ Abstract Congenital nasal piriform aperture stenosis and choanal atresia are types of nasal obstructions that can be life threatening to infants if left untreated. While there has been numerous reports on both of them...
Related ArticlesAudiological assessment of neonatal hyperbilirubinemia. Int J Pediatr Otorhinolaryngol. 2020 May 20;135:110126 Authors: Mandour YM, El Sayed MA, El Sayed Morgan A, Bassam R, Fadl H, Elrefae A Abstract OBJECT: To evaluate the hearing of infants with history of neonatal hyperbilirubinemia using ABR. METHODS: A prospective randomized study carried on 100 infants whose hearing was assessed by ABR. Infants were allocated into two...
Related ArticlesSolitary juvenile xanthogranuloma of the hypopharynx. Clinico-pathologic study in a child with β-Thalassemia Major and Cutaneous Mastocytosis. Int J Pediatr Otorhinolaryngol. 2020 May 05;135:110088 Authors: de Soccio G, Savastano V, Minasi S, Bertin S, Serafini M, Vittori T, Riminucci M, Corsi A Abstract Juvenile Xanthogranuloma (JXG), the most common pediatric non-Langerhans cell histiocytosis, may rarely occur in association with Neurofibromatosis...
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Related Articles15-hydroxy-6α,12-epoxy-7β,10αH,11βH-spiroax-4-ene-12-onesensitizesrectal tumor cells to anti-PD1 treatment through agonism of CD11b. Immunopharmacol Immunotoxicol. 2020 Jun 07;:1-17 Authors: Zhao Q, Lu L, Du G, Wang Z, Li X, Ju F Abstract Purpose: Although immunotherapies have resulted in durable clinical responses, not all tumor types have seen substantial benefit. Extensive recruitment and accumulation of immunosuppressive myeloid cells...
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Related ArticlesPD-1/PD-L1 negative schwannoma mimicking obstructive bronchial malignancy: A case report. Thorac Cancer. 2020 Jun 08;: Authors: Zhou D, Xing X, Fan J, Zhang Y, Liu J, Gong Y Abstract Schwannomas are homogeneous tumors of schwann cells and occur at peripheral and cranial nerves on the upper limbs, the head and neck area. Rarely, a bronchial schwannoma may appear in the lung and be misdiagnosed as lung neoplasms. Here, we report a 56-year...
Related ArticlesMalignant Peritoneal Mesothelioma as a Rare Cause of Dyspeptic Complaints and Ascites: A Diagnostic Challenge. GE Port J Gastroenterol. 2020 Apr;27(3):197-202 Authors: Marques de Sousa S, Pereira F, Duarte M, Marques M, Vázquez D, Marques C Abstract Introduction: Malignant peritoneal mesothelioma (MPM) is a rare malignancy of the mesothelial cells in the peritoneum. The best-defined risk factor is asbestos exposure, but germline mutations...
Related ArticlesSevere Aplastic Anemia Developed after Thymectomy: A Case Report and Literature Review. Case Rep Hematol. 2020;2020:7819321 Authors: Duarte Rodrigues BC, Freire PJG, Campos BPES, Vieira JO, Gouveia PADC Abstract Thymus neoplasms are frequently related to paraneoplastic autoimmune manifestations. Its most common associations are myasthenia gravis and pure red cell aplasia. Aplastic anemia has been increasingly documented as an initial...
Related ArticlesSimultaneous multiple primary cancers with concomitant inflammatory myofibroblastic tumor: a case report. Int J Clin Exp Pathol. 2020;13(5):1212-1215 Authors: Lv X, Ye J, Jiang G, Wang Y, Lv J, Wang Y Abstract Multiple primary cancers are of rare occurrence. Most multiple primary cancers are metachronous multiple primary cancers, while simultaneous multiple primary cancers are rare. Inflammatory myofibroblastic tumors are rare. Inflammatory...
Related ArticlesChance to rein in a cancer--Spontaneous regression of lung carcinoma (1988-2018): a 30-year perspective. Int J Clin Exp Pathol. 2020;13(5):1190-1196 Authors: Zhang J, Wang H, Li C, Qian H Abstract BACKGROUND: Spontaneous regression of tumor is an extremely rare phenomenon in the oncology field and even rarer for lung cancer. However, the underlying mechanism is poorly understood. Summarizing the available clinical information and the...
Related ArticlesSchwannoma of head-and-neck region: A clinical chameleon - Report of two cases occurring at rare sites with unusual clinical manifestations. J Oral Maxillofac Pathol. 2020 Jan-Apr;24(1):164-167 Authors: Kumar M, Rao M, Elhence P, Kaushal D, Yadav T Abstract Schwannomas are rare benign encapsulated neoplasms that usually do not arise in the nasal and oral cavities. Only about 25% of the schwannomas are located in the head-and-neck region....
Related ArticlesQuantitative analysis of tumor-associated tissue eosinophils and tumor-associated blood eosinophils in oral squamous cell carcinoma. J Oral Maxillofac Pathol. 2020 Jan-Apr;24(1):131-137 Authors: Siddiqui S, Jaiswal R, Hashmi GS Abstract Background: Stromal response to cancer is usually characterized by intense lymphoplasmacytic infiltrate. However, recently, the attention has shifted to tumor-associated tissue eosinophils (TATE). Tumor-associated...
Related ArticlesMalignant teratoid tumor of the thyroid gland: an aggressive primitive multiphenotypic malignancy showing organotypical elements and frequent DICER1 alterations-is the term "thyroblastoma" more appropriate? Virchows Arch. 2020 Jun 07;: Authors: Agaimy A, Witkowski L, Stoehr R, Cuenca JCC, González-Muller CA, Brütting A, Bährle M, Mantsopoulos K, Amin RMS, Hartmann A, Metzler M, Amr SS, Foulkes WD, Sobrinho-Simões M, Eloy C Abstract Primary...
Related ArticlesCurrent Options for Third-line and Beyond Treatment of Metastatic Colorectal Cancer. Spanish TTD Group Expert Opinion. Clin Colorectal Cancer. 2020 Apr 20;: Authors: Fernández-Montes A, Grávalos C, Pericay C, Safont MJ, Benavides M, Élez E, García-Alfonso P, García-Paredes B, Carrato A, Aranda E Abstract Colorectal cancer (CRC) is a public health problem: it is the third most common cancer in men (746,000 new cases/year) and the second...
Related ArticlesSmall Lymphocytic Lymphoma Mimicking Primary Cutaneous Marginal Zone Lymphoma with Colonization of Germinal Center Follicles. J Cutan Pathol. 2020 Jun 07;: Authors: LeBlanc RE, Carter JB, Kaur P, Lansigan F Abstract Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is primarily a disease of older adults and is occasionally an incidental finding on skin biopsies accompanying epithelial neoplasms and insect bite reactions....
Related ArticlesRetrospective Study of Buccal Mucosal Salivary Neoplasms. Head Neck Pathol. 2020 Jun 06;: Authors: Alramadhan SA, Fitzpatrick SG, Cohen DM, Bhattacharyya I, Islam MN Abstract Salivary gland neoplasms of the buccal mucosa are relatively rare and often present with an unusual histopathologic profile when compared with other intraoral locations. We present a series of minor salivary gland neoplasms of the buccal mucosa and discuss demographics,...
Related ArticlesSurgical management of peripheral nerve sheath tumours in children, with special consideration of neurofibromatoses. Childs Nerv Syst. 2020 Jun 06;: Authors: Zipfel J, Al-Hariri M, Gugel I, Haas-Lude K, Grimm A, Warmann S, Krimmel M, Mautner VF, Tatagiba M, Schuhmann MU Abstract INTRODUCTION: Peripheral nerve sheath tumours in children are a rare and heterogeneous group, consisting mostly of benign tumours as well as malignant neoplasms....
Related ArticlesA clinically silent tumour of adrenal myelolipoma: A case report. Int J Surg Case Rep. 2020 Jun 01;72:63-65 Authors: Azizan N, Myint O, Wynn AA, Thein TT, Hayati F, Nik Lah NAS Abstract INTRODUCTION: Adrenal myelolipoma is a rare, non-functional, benign neoplasm which is constituted of mature haematopoietic elements and adipose tissues in various proportions. It is diagnosed accidentally and frequently with the widespread use of imaging...
Related ArticlesPrimary hepatic neuroendocrine tumor: A case report and literature review. Int J Surg Case Rep. 2020 May 30;72:1-4 Authors: Costa AC, Santa-Cruz F, Guimarães H, Paz AR, Costa EAC, Figueiredo JL, Ferraz ÁAB Abstract INTRODUCTION: Primary hepatic neuroendocrine tumors (PHNETs) are extremely rare, having less than 200 cases reported in the literature. PRESENTATION OF CASE: A 51-year-old woman presenting with mild intensity sharp...
Related ArticlesPolypoidal choroidal vasculopathy as a complication of choroidal osteoma: A case report. Medicine (Baltimore). 2020 May;99(20):e19927 Authors: Kim D, Ryu G, Sagong M Abstract INTRODUCTION: Choroidal osteoma (CO) is a rare benign tumor that particularly affects young, healthy women. Its prognosis is influenced by complications, such as choroidal neovascularization (CNV), subretinal hemorrhage, subretinal fluid (SF), decalcification status,...
Related Articles[Hypoparathyroidism treated with recombinant human parathyroid hormone [rhPTH(1-84)]]. Medicina (B Aires). 2020;80(3):289-291 Authors: Ramacciotti CF, Pereyra MC, Cohen EN Abstract Hypoparathyroidism (HypoPT) is a rare disease characterized by low calcium and inappropriately low circulating parathormone levels. We present the case of a 25-year-old high-performance athlete male, with history of HypoPT after total thyroidectomy for papillary...
Related Articles[Mixed desmoplastic melanoma]. Medicina (B Aires). 2020;80(3):280-284 Authors: Simionato C, Minaudo C, Mosquera T, Marini M, Saponaro A, Vigovich F Abstract Desmoplastic melanoma is a rare presentation of melanoma with a different clinical behavior compared to other histological variants. Its diagnosis in early stages is a challenge due to its variable clinical presentation, with a predominant dermal component and the frequent absence...
Related Articles[Efficacy of Oral Cyclophosphamide for Treatment of Refractory T-cell Large Granular Lymphocytic Leukemia Accompanied with Pure Erythrocyte Aplastic Anemia]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2020 Apr;28(2):418-423 Authors: Zhao Y, Chen ZW, Ye HY, Gu J, Xu XL, Qi YL, Ling YW Abstract OBJECTIVE: To explore the clinical effects of oral small dose of cyclophosphamide (CTX) in the treatment of T-cell large granular lymphocytic leukemia...
Related ArticlesA review of retroperitoneal liposarcoma genomics. Cancer Treat Rev. 2020 Jun;86:102013 Authors: Tyler R, Wanigasooriya K, Taniere P, Almond M, Ford S, Desai A, Beggs A Abstract Retroperitoneal liposarcomas are rare tumours that carry a poorer prognosis than their extremity counterparts. Within their subtypes - well differentiated (WDL), dedifferentiated (DDL), myxoid (MLS) and pleomorphic (PLS) - they exhibit a diverse genomic landscape....
Related ArticlesThymic epithelial tumors: From biology to treatment. Cancer Treat Rev. 2020 Jun;86:102014 Authors: Conforti F, Pala L, Giaccone G, De Pas T Abstract In the last few years, meaningful advances have been made in the knowledge of the biology of Thymic Epithelial Tumors (TETs). Data available suggest that in most cases, the different histological subtypes could be distinct biological entities, characterized by specific molecular aberrations,...
Related ArticlesHealth complaints and work experiences among adults with neurofibromatosis 1. Occup Med (Lond). 2019 Dec 07;69(7):504-510 Authors: Fjermestad KW Abstract BACKGROUND: Neurofibromatosis type 1 (NF1) is a rare genetic disorder with usually benign nerve tumours, skin problems, pain and cardiovascular problems among common complications. AIMS: To examine work participation and experiences in relation to health complaints among adults...
Related ArticlesPAX8 positivity in nested variant of urothelial carcinoma: a potential diagnostic pitfall. Hum Pathol. 2019 12;94:11-15 Authors: Legesse T, Matoso A, Epstein JI Abstract Nested variant of urothelial carcinoma is a rare variant of urothelial carcinoma morphologically characterized by infiltrative nests of cytologically bland urothelial cells. It is widely recognized that nested variant of urothelial carcinoma can closely mimic von Brunn...
Related ArticlesPrimary adenocarcinoma of the bladder lacks mismatch repair deficiency and demonstrates PD-L1 expression in tumor-infiltrating immune cells, with implications in both diagnosis and therapeutics. Hum Pathol. 2019 12;94:58-63 Authors: Jones D, Guan JJ, Calagua C, Hansel DE, Epstein JI, Ye H Abstract Primary adenocarcinoma of the bladder is a rare and highly aggressive disease with no standard therapy. Effectiveness of immune checkpoint...
Related ArticlesMetastatic tumor to the orbital cavity from a primary carcinoma of the uterine cervix : a case report. J Med Invest. 2019;66(3.4):355-357 Authors: Kagusa H, Mizobuchi Y, Nakajima K, Fujihara T, Bando Y, Takagi Y Abstract Metastatic tumors to the orbit of the eye, especially from primary carcinomas of the uterine cervix are very rare. A 64-year-old woman with a history of carcinoma of the uterine cervix presented with right eye pain and...
Related ArticlesOsteolytic primary bone lymphoma in the multiple bones. J Med Invest. 2019;66(3.4):347-350 Authors: Yagi S, Zheng R, Nishiyama S, Kawabata Y, Ise T, Sugiura K, Yoshinari H, Nishisho T, Bando Y, Kagawa K, Fukuda D, Soga T, Saijo Y, Kusunose K, Yamaguchi K, Yamada H, Soeki T, Wakatsuki T, Kawahito S, Akaike M, Sata M Abstract Primary non-Hodgkin bone lymphoma (PBL) can involve solitary or multiple destructive bone lesions such as those...
Related ArticlesAnesthesia for a long-term anorexic patient with end-stage liver cirrhosis : A Case Report. J Med Invest. 2019;66(3.4):337-339 Authors: Hirose K, Ogura M, Yamada Y Abstract Recent advancements in intensive care have increased the number of severe anorexia nervosa patients presenting for surgery. We provided anesthesia to a patient who had a 22-year history of anorexia with life-threatening cirrhosis. Although surgery should be avoided...
Related ArticlesLow-Impedance 3D PEDOT:PSS Ultramicroelectrodes. Front Neurosci. 2020;14:405 Authors: Jones PD, Moskalyuk A, Barthold C, Gutöhrlein K, Heusel G, Schröppel B, Samba R, Giugliano M Abstract The technology for producing microelectrode arrays (MEAs) has been developing since the 1970s and extracellular electrophysiological recordings have become well established in neuroscience, drug screening and cardiology. MEAs allow monitoring of long-term...
Related ArticlesExploring the Feasibility and Effects of a Ketogenic Diet in Patients With CNS Malignancies: A Retrospective Case Series. Front Neurosci. 2020;14:390 Authors: Panhans CM, Gresham G, Amaral JL, Hu J Abstract Background: Recently, the ketogenic diet has been proposed as an adjunct treatment for a range of medical conditions including weight loss, diabetes, cancer, and neurodegenerative diseases. Because malignant CNS tumors are highly dependent...
Related ArticlesTranscranial Direct Current Stimulation Over Prefrontal Areas Improves Psychomotor Inhibition State in Patients With Traumatic Brain Injury: A Pilot Study. Front Neurosci. 2020;14:386 Authors: Zhang X, Liu B, Li N, Li Y, Hou J, Duan G, Wu D Abstract Objectives: Many post-traumatic patients with minimally conscious state are complicated by psychomotor inhibition state (PIS), which impedes further rehabilitation. The treatment of PIS is...
Related ArticlesTracing the Origins of the Pituitary Adenylate-Cyclase Activating Polypeptide (PACAP). Front Neurosci. 2020;14:366 Authors: Cardoso JCR, Garcia MG, Power DM Abstract Pituitary adenylate cyclase activating polypeptide (PACAP) is a well-conserved neuropeptide characteristic of vertebrates. This pluripotent hypothalamic neuropeptide regulates neurotransmitter release, intestinal motility, metabolism, cell division/differentiation, and immunity....
Related ArticlesA 3D Fully Convolutional Neural Network With Top-Down Attention-Guided Refinement for Accurate and Robust Automatic Segmentation of Amygdala and Its Subnuclei. Front Neurosci. 2020;14:260 Authors: Liu Y, Nacewicz BM, Zhao G, Adluru N, Kirk GR, Ferrazzano PA, Styner MA, Alexander AL Abstract Recent advances in deep learning have improved the segmentation accuracy of subcortical brain structures, which would be useful in neuroimaging studies...
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Related ArticlesComparison of Postoperative Quality of Life among Three Different Reconstruction Methods After Proximal Gastrectomy: Insights From the PGSAS Study. World J Surg. 2020 Jun 06;: Authors: Yabusaki H, Kodera Y, Fukushima N, Hiki N, Kinami S, Yoshida M, Aoyagi K, Ota S, Hata H, Noro H, Oshio A, Nakada K Abstract BACKGROUND: Proximal gastrectomy (PG) has become an increasingly preferred procedure for early cancer in the upper third of the stomach,...
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Related ArticlesSARS-CoV-2 RNA from droplets to faeces: a new focus for proctologists. Correspondence. Int J Surg. 2020 Jun 05;: Authors: Brusciano L, Gambardella C, Gualtieri G, Tolone S, Lucido FS, Del Genio G, Terracciano G, Docimo L PMID: 32512050 [PubMed - as supplied by publisher]
Related ArticlesPreoperative hypoalbuminemia is an independent risk factor for postoperative complications in Crohn's disease patients with normal BMI: a cohort study. Int J Surg. 2020 Jun 04;: Authors: Ge X, Liu H, Tang S, Wu Y, Pan Y, Liu W, Qi W, Ye L, Cao Q, Zhou W Abstract BACKGROUND: Malnutrition is universal in Crohn's disease (CD). The body mass index (BMI) is used to assess nutritional status to predict postoperative complications in CD...
Children returning to schools following COVID-19: a balance of probabilities - Letter to the Editor.
Related ArticlesChildren returning to schools following COVID-19: a balance of probabilities - Letter to the Editor. Int J Surg. 2020 Jun 04;: Authors: Khattab N, Abbas A, Abbas AR, Memon SF PMID: 32505646 [PubMed - as supplied by publisher]
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Xanthogranuloma is a rare benign tumour, part of the non-Langerhans cell histiocytosis group, uncommon in adults and even less common in the paranasal sinuses. Despite its benign nature, it mimics neoplasm due to its local effects which can have serious functional consequences depending on the anatomical location. We present the rare case of a young lady who presented insidiously with a maxillary sinus xanthogranuloma and was treated with endoscopic resection. Tissue diagnosis is of paramount importance...
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Related ArticlesReply to Letter to the Editor regarding "Treatment modality and outcomes in larynx cancer patients: A sex-based evaluation". Head Neck. 2020 Jun 08;: Authors: Kejner AE, Li H, Li EY, Porterfield JZ PMID: 32511828 [PubMed - as supplied by publisher]
Related ArticlesTreatment modality and outcomes in larynx cancer patients. Head Neck. 2020 Jun 08;: Authors: Huang GJ, Huang ZH PMID: 32511816 [PubMed - as supplied by publisher]
Related ArticlesEndoscopy-assisted transoral resection of a parapharyngeal space schwannoma without mandibular dissection. Auris Nasus Larynx. 2020 Jun 05;: Authors: Yamamoto K, Kurose M, Yadomura R, Yajima R, Okuni T, Takano K Abstract Of the schwannomas that arise from the parapharyngeal space, those in the high cervical region are particularly invasive, requiring mandibular dissection. Because these tumors are benign, however, excessive surgical invasion...
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