Related ArticlesNeural activity of functionally different retinal ganglion cells can be robustly modulated by high-rate electrical pulse trains. J Neural Eng. 2020 Jun 08;: Authors: Muralidharan M, Guo T, Shivdasani MN, Tsai D, Fried S, Li L, Dokos S, Morley JW, Lovell NH Abstract PURPOSE: This study focused on characterising the response of four major functionally-different retinal ganglion cells (RGCs) to a high frequency stimulus (HFS) paradigm. ...
Tue Jun 09, 2020 15:00
Related ArticlesStability of flexible thin-film metallization stimulation electrodes: analysis of explants after first-in-human study and improvement of <i>in vivo</i> performance. J Neural Eng. 2020 Jun 08;: Authors: Čvančara P, Boretius T, López-Álvarez VM, Maciejasz P, Andreu D, Raspopovic S, Petrini FM, Micera S, Granata G, Fernandez E, Rossini PM, Yoshida K, Jensen W, Divoux JL, Guiraud D, Navarro X, Stieglitz T Abstract OBJECTIVE: Micro-fabricated...
Tue Jun 09, 2020 15:00
Related ArticlesHow much of the BOLD-fMRI signal can be approximated from simultaneous EEG data: relevance for the transfer and dissemination of neurofeedback interventions. J Neural Eng. 2020 Jun 08;: Authors: Simoes M, Abreu R, Direito B, Sayal A, Castelhano J, de Carvalho P, Castelo-Branco M Abstract OBJECTIVE: fMRI-based neurofeedback (NF) interventions represent the method of choice for the neuromodulation of localized brain areas. Although we have...
Tue Jun 09, 2020 15:00
Related ArticlesDetection and classification of single-trial movement-related cortical potentials associated with functional lower limb movements. J Neural Eng. 2020 Jun 08;: Authors: Jochumsen M, Niazi IK Abstract OBJECTIVES: Brain-computer interfaces that activate exoskeletons based on decoded movement-related activity have been shown to be useful for stroke rehabilitation. With the advances in the development of exoskeletons it is possible to replicate...
Tue Jun 09, 2020 15:00
Deviations from a clinical pathway post pancreatoduodenectomy predict 90-day unplanned re-admission.
Related ArticlesDeviations from a clinical pathway post pancreatoduodenectomy predict 90-day unplanned re-admission. Future Oncol. 2020 Jun 08;: Authors: Karunakaran M, Barreto SG, Singh MK, Kapoor D, Chaudhary A Abstract Aim: To determine the frequency and relevance of deviations from a post pancreatoduodenectomy (PD) clinical care pathway. Materials & methods: A retrospective analysis using a prospectively maintained database of a post-PD clinical...
Tue Jun 09, 2020 14:58
Related ArticlesSelinexor: a first-in-class SINE compound for treatment of relapsed refractory multiple myeloma. Future Oncol. 2020 Jun 08;: Authors: Richard S, Richter J, Jagannath S Abstract The progression of multiple myeloma is accompanied by complex cytogenetic and epigenetic alterations that include mutation or functional inactivation of tumor suppressor proteins and overexpression of oncoproteins. Patients whose myeloma is refractory to the three...
Tue Jun 09, 2020 14:58
Related ArticlesDiagnosis and treatment of limbic encephalitis in the cancer patient. Future Oncol. 2020 Jun 08;: Authors: Kyritsis AP, Markoula S, Alexiou G, Asimakopoulos A, Jabbour P, Fotopoulos A, Sioka C Abstract Limbic encephalitis is an inflammatory process involving the limbic structures of the brain, manifested with short-term memory deficits, confusion, depression and seizures. It is usually a paraneoplastic condition but it may also appear...
Tue Jun 09, 2020 14:58
Related ArticlesSunitinib inhibits PD-L1 expression in osteosarcoma by targeting STAT3 and remodels the immune system in tumor-bearing mice. Future Oncol. 2020 Jun 08;: Authors: Duan XL, Guo JP, Li F, Xiu C, Wang H Abstract Aim: Exploring the mechanisms of the combination therapy using VEGFR-TKI and immune checkpoint inhibitors might be useful to control the development of osteosarcoma. Materials & methods: The expression of PD-L1 and STAT3 in osteosarcoma...
Tue Jun 09, 2020 14:58
82 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/06/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Jun 09, 2020 14:56
27 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: epilepsy treatment These pubmed results were generated on 2020/06/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Jun 09, 2020 14:53
Related ArticlesProtocatechuic acid inhibits proliferation, migration and inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes. Artif Cells Nanomed Biotechnol. 2020 Dec;48(1):969-976 Authors: Wu H, Wang J, Zhao Q, Ding Y, Zhang B, Kong L Abstract Rheumatoid arthritis (RA) is a chronic joint inflammatory disease that is closely associated with dysregulation of fibroblast-like synoviocytes (FLSs). Protocatechuic acid (PCA), a phenolic...
Tue Jun 09, 2020 14:53
Alcohol use disorder (AUD) patients comorbid with hepatitis C virus (HCV) infection (HCV + AUD) could have progressively severe clinical sequels of liver injury and inflammation. Serum zinc and several polyunsaturated fatty acids (PUFAs) get dysregulated in AUD as well as HCV. However, the extent of dysregulation of PUFAs and zinc deficiency and their interaction in HCV + AUD as a comorbid pathology has not been studied. We examined the role of dysregulation of FAs and low zinc in HCV + AUD patients....
Tue Jun 09, 2020 12:50
Publication date: Available online 8 June 2020Source: Journal of Surgical EducationAuthor(s): Kate V. Meriwether, Sara B. Petruska, Wyatt N. Seed, Jeremy T. Gaskins, J. Ryan Stewart
Tue Jun 09, 2020 14:50
Related ArticlesA Genetic Screen To Identify Genes Influencing the Secondary Redox Couple NADPH/NADP+ in the Yeast Saccharomyces cerevisiae. G3 (Bethesda). 2020 01 07;10(1):371-378 Authors: Yadav S, Mody TA, Sharma A, Bachhawat AK Abstract NADPH is an important cofactor in the cell. In addition to its role in the biosynthesis of critical metabolites, it plays crucial roles in the regeneration of the reduced forms of glutathione, thioredoxins and peroxiredoxins....
Tue Jun 09, 2020 14:49
Related ArticlesDeuterium Kinetic Isotope Effects Resolve Low-Temperature Substrate Radical Reaction Pathways and Steps in B12-Dependent Ethanolamine Ammonia-Lyase. Biochemistry. 2019 09 03;58(35):3683-3690 Authors: Kohne M, Li W, Zhu C, Warncke K Abstract The first-order reaction kinetics of the cryotrapped 1,1,2,2-2H4-aminoethanol substrate radical intermediate state in the adenosylcobalamin (B12)-dependent ethanolamine ammonia-lyase (EAL) from Salmonella...
Tue Jun 09, 2020 14:49
5478 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/06/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Jun 09, 2020 14:49
Abstract Introduction Second-generation high-resolution peripheral quantitative computed tomography (HR-pQCT) has provide higher quality of bone images with a voxel size of 61 µm, enabling direct measurements of trabecular thickness. In addition to the standard parameters, the non-metric trabecular parameters such as trabecular morphology (plate to rod-like structures), connectivity, and anisotropy can also be analyzed. The purpose...
Tue Jun 09, 2020 03:00
The frequency-following response (FFR) is an EEG-based potential used to characterize the brainstem encoding of complex sounds. Adopting techniques from auditory signal processing, we assessed the degree to which FFRs encode important properties of cochlear processing (e.g. nonlinearities) and their relation to speech-in-noise (SIN) listening skills. Based on the premise that normal cochlear transduction is characterized by rectification and compression, we reasoned these nonlinearities would create...
Tue Jun 09, 2020 14:46
We previously reported that intraspinal transplantation of human amniotic mesenchymal stem cells (hAMSCs) promotes functional recovery in a rat model of acute traumatic spinal cord injury (SCI). However, whether intravenous transplantation of hAMSCs also has therapeutic benefit remains uncertain. In this study, we assessed whether intravenous transplantation of hAMSCs improves outcomes in rats with acute traumatic SCI. In addition, the potential mechanisms underlying the possible benefits of this...
Tue Jun 09, 2020 14:46
Correcting for eddy currents, movement-induced distortion and gradient inhomogeneities is imperative when processing diffusion MRI (dMRI) data, but is highly computing resource-intensive. Recently, Compute Unified Device Architecture (CUDA) was implemented for the widely-used eddy-correction software, ‘eddy’, which reduces processing time and allows more comprehensive correction. We investigated processing speed, performance and compatibility of CUDA-enabled eddy-current correction processing compared...
Tue Jun 09, 2020 14:46
The repeated administration of high doses of amphetamine has been shown to cause long-lasting depletions of striatal dopamine which, when substantial enough, have been shown to result in cognitive and motor impairment. These amphetamine-induced lesions are slightly larger in males than that in females and can be partially ameliorated by pretreatment with antioxidants. The objective of the present study was to replicate these two latter observations using an amphetamine dosing regimen that yields...
Tue Jun 09, 2020 14:46
Chronic pain results in a variety of neural adaptations, many of which are maladaptive and result in hypersensitivity to pain. In humans, this hypersensitivity can be debilitating and treatment options are limited. Fortunately, there are numerous animal models that mimic clinical populations and have the potential to aid in the evaluation of underlying mechanisms and ultimately the development of better treatments. One of these is the complete Freund’s adjuvant (CFA)-model of chronic inflammatory...
Tue Jun 09, 2020 14:46
The mammalian neocortex is composed of six major layers of neurons. Each group of neurons in the cortical layers has distinct characteristics based on the expression of specific genes and connectivity patterns of neural circuits. Neuronal subtype transition and regional identity acquisition are established by temporal cues and interaction between several transcription factors during neurogenesis. The impairment of cortical lamination or neural circuits results in a wide range of neurodevelopmental...
Tue Jun 09, 2020 14:46
Besides degradation, lysosomes can also carry molecules for secretion out of the cell, such as ATP and cytokines, during unconventional secretion. Phosphatidylinositols and their metabolizing enzymes play important roles in the sorting and trafficking of lysosomal materials through the trans-Golgi network. The present study reveals a new function of phosphatidylinositol kinase-III alpha in the ‘kiss-and-run’ fusion of lysosomes at the plasma membrane to release ATP from microglia.
Tue Jun 09, 2020 14:46
Waggle needling, a classical anti-spastic needling technique characterized by combination of acupuncture with joint movement, has gained increasing popularity of spasticity treatment in China. This study was designed to compare the anti-spastic effect of waggle needling to the routine needling and to explore its underlying mechanism. We established post-stroke spasticity model based on ischemia stroke operation (middle cerebral artery occlusion). Rats were divided into six groups: normal control...
Tue Jun 09, 2020 14:46
The brain’s default mode network (DMN) has become closely associated with self-referential mental activity, particularly in the resting-state. Prior reports point that the sex hormones are potent modulators of brain plasticity and functional connectivity. However, it is uncertain whether changes in ovarian hormones, as occur during the monthly menstrual cycle, substantially affects the functional connectivity of DMN. Here, we employed a Self-Awareness Scale (SAS) and the resting-state functional...
Tue Jun 09, 2020 14:46
Histone deacetylase-6 modulates amyloid beta-induced cognitive dysfunction rats by regulating PTK2B.
The aim of this study was to investigate the effects of histone deacetylase-6 (HDAC6) on the functional and pathological changes of the amyloid beta (Aβ)-induced cognitive dysfunction rats by regulating protein tyrosine kinase 2 beta (PTK2B). Ninety Sprague Dawley rats were randomly divided into nine groups, consisting of five experimental groups and four control groups. In five experimental groups, Aβ1–42 was infused intracerebroventricularly and 3 days later, rats in each group were infused intracerebroventricularly...
Tue Jun 09, 2020 14:46
Facial trustworthiness can influence trust behavior. The outcome may be concordant (a person with a trustworthy face who engages in reciprocal behavior) or conflicting (a person with a trustworthy face who does not reciprocate). This study investigated the temporal features of processing different outcomes following trustworthy or untrustworthy faces. Thirty-one college students participated in a decision-making task in which they were shown a face and were asked to judge whether the person would...
Tue Jun 09, 2020 14:46
Neural transplantation is a promising modality for treatment of neurodegenerative diseases, traumatic brain injury and stroke. Biocompatible scaffolds with optimized properties improve the survival of transplanted neural cells and differentiation of progenitor cells into the desired types of neurons. Silk fibroin is a biocompatible material for tissue engineering. Here, we describe thin-film scaffolds based on photocrosslinked methacrylated silk fibroin (FBMA). These scaffolds exhibit an increased...
Tue Jun 09, 2020 14:46
To investigate the preattentive change detection in preschool children with attention deficit hyperactivity disorder (ADHD), we compared the mismatch negativity (MMN) and P3a of event-related potentials (ERPs) between preschool ADHD and normal children using three-stimulus oddball paradigm. Analyzing MMN and P3a components, we found that MMN elicited by deviants and P3a elicited by novelty were significantly reduced in patients than in controls. In addition, the P3a amplitude was positive correlated...
Tue Jun 09, 2020 14:46
Publication date: Available online 9 June 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Lu Qin, Cong Zhang, Junqing Yue, Min Xie
Tue Jun 09, 2020 14:46
Publication date: Available online 9 June 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): John W. Steinke, Monica G. Lawrence, W. Gerald Teague, Thomas J. Braciale, James T. Patrie, Larry Borish
Tue Jun 09, 2020 14:46
Publication date: Available online 8 June 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Daphne S. Bakker, Stefan Nierkens, Edward F. Knol, Barbara Giovannone, Eveline M. Delemarre, Jorien van der Schaft, Femke van Wijk, Marjolein S. de Bruin-Weller, Julia Drylewicz, Judith L. Thijs
Tue Jun 09, 2020 14:46
Publication date: Available online 8 June 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Kelly M. O’Shea, Mark Rochman, Tetsuo Shoda, Nives Zimmermann, Julie Caldwell, Marc E. Rothenberg
Tue Jun 09, 2020 14:46
Publication date: Available online 8 June 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Dawn C. Newcomb
Tue Jun 09, 2020 14:46
Related ArticlesThe relationship between depression risk perception and self-help behaviours in high risk Canadians: a cross-sectional study. BMC Public Health. 2020 Jun 06;20(1):876 Authors: Warner E, Nannarone M, Smail-Crevier R, Manuel D, Lashewicz B, Patten S, Schmitz N, MacQueen G, Wang JL Abstract BACKGROUND: Self-help may reduce the risk of depression, and risk perception of depression may influence initiating self-help. It is unknown how risk...
Tue Jun 09, 2020 14:42
Related ArticlesHuman Toxoplasma gondii infection in Nigeria: a systematic review and meta-analysis of data published between 1960 and 2019. BMC Public Health. 2020 Jun 06;20(1):877 Authors: Karshima SN, Karshima MN Abstract BACKGROUND: Over 70% of the worlds' population is infected by Toxoplasma gondii; a pathogen capable of causing cerebral toxoplasmosis in HIV patients and neonatal complications like miscarriage, chorioretinitis, hydrocephalus, cerebral...
Tue Jun 09, 2020 14:42
Abstract The immune system of cancer patient gets compromised because of cancer therapy, surgery and malignancy and thus the probability of infection are increased than the general patients. Immunosuppression can expose cancer patients to serious complications which can lead to delay in diagnosis and unnecessary hospitalizations that may adversely affect the prognosis of the disease. Patients who received chemotherapy or surgery within the 30 days before COVID‐19 pandemic have more risk of infection...
Mon Jun 08, 2020 20:50
Abstract Acute herpes zoster lesions in most cases are self‐ limited except in older and immunocompromised patients, wherein the pain can cause significant suffering. Postherpetic neuralgia is a painful situation for patients that can compromise the quality of life. Here, we report a 30‐year‐old healthy young man who developed treatment‐resistant post‐herpetic neuralgia after herpes zoster (4th/5th thoracic segment) without any underlying immunocompromised state. He also developed some cystic lesions,...
Mon Jun 08, 2020 17:57
Mon Jun 08, 2020 17:52
Mon Jun 08, 2020 17:30
Abstract The differential diagnosis between lichenoid drug eruption (LDE) and lichen planus (LP) is difficult due to similar clinical and histological signs, but important for treatment and prognosis. The purpose of this study was to propose the new diagnosis method for differentiate LDE from lichen planus. During 2015‐2018, 20 patients with confirmed LDE, 13 patients with LP and 134 controls were examined and treated at the Lenoblcenter. All enrolled patients were underwent the injection of 0.5 mL...
Mon Jun 08, 2020 17:19
Lets discuss a clinical case with CXR and CT findings and how to integrate clinically. A case of breathlessness.Famous Radiology Blog http://www.sumerdoc.blogspot.com TeleRad Providers at www.teleradproviders.com Mail us at sales@teleradproviders.com
Tue Jun 09, 2020 14:37
Related ArticlesThe mosquitoes of Armenia: review of knowledge and results of a field survey with first report of Aedes albopictus. Parasite. 2020;27:42 Authors: Paronyan L, Babayan L, Manucharyan A, Manukyan D, Vardanyan H, Melik-Andrasyan G, Schaffner F, Robert V Abstract BACKGROUND: In 2016, a field study was implemented in all Armenian provinces in order to update knowledge on the presence and distribution of both native and invasive mosquito...
Tue Jun 09, 2020 15:05
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