Antibiotics, Vol. 9, Pages 383: Application of Rank Annihilation Factor Analysis for Antibacterial Drugs Determination by Means of pH Gradual Change-UV Spectral Data Antibiotics doi: 10.3390/antibiotics9070383 Authors: Esteki Dashtaki Heyden Simal-Gandara The main objective of this study was to develop a simple and efficient spectrophotometric technique combined with chemometrics for the simultaneous determination of sulfamethoxazole (SMX) and trimethoprim (TMP) in drug...
Antibiotics, Vol. 9, Pages 381: Synthesis and Evaluation of the Antibacterial Activities of 13-Substituted Berberine Derivatives Antibiotics doi: 10.3390/antibiotics9070381 Authors: Olleik Yacoub Hoffer Gnansounou Benhaiem-Henry Nicoletti Mekhalfi Pique Perrier Hijazi Baydoun Raymond Piccerelle Maresca Robin The biological activities of berberine, a natural plant molecule, are known to be affected by structural modifications, mostly...
Antibiotics, Vol. 9, Pages 382: Colonization of Methicillin-Resistant Staphylococcus aureus (MRSA) among Medical Students in Tertiary Institution in Central Malaysia Antibiotics doi: 10.3390/antibiotics9070382 Authors: Sanjiv Rampal Nur Hidayah Zainuddin Nur Athirah Elias Tengku Zetty Maztura Tengku Jamaluddin Sandra Maniam Seoh Wei Teh Suresh Kumar Subbiah Methicillin-resistant Staphylococcus aureus or MRSA infection is virulent and presents with a broad spectrum of...
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Antibodies, Vol. 9, Pages 31: Identification of Specific IgE Antibodies and Asthma Control Interaction and Association Using Cluster Analysis in a Bulgarian Asthmatic Children Cohort Antibodies doi: 10.3390/antib9030031 Authors: Snezhina Lazova Tsvetelina Velikova Stamatios Priftis Guergana Petrova (1) Background: Asthma is a complex heterogeneous disease that likely comprises several distinct disease phenotypes, where the clustering approach has been used to classify the heterogeneous...
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Antioxidants, Vol. 9, Pages 590: The Nitric Oxide System in Peripheral Artery Disease: Connection with Oxidative Stress and Biopterins Antioxidants doi: 10.3390/antiox9070590 Authors: Ahmed Ismaeel Evlampia Papoutsi Dimitrios Miserlis Ramon Lavado Gleb Haynatzki George P. Casale William T. Bohannon Robert S. Smith Jack Leigh Eidson Robert Brumberg Aaron Hayson Jeffrey S. Kirk Carlos Castro Ian Sawicki Charalambos Konstantinou Luke P. Brewster Iraklis...
Antioxidants, Vol. 9, Pages 591: Placenta-Derived Mesenchymal Stem Cells Restore the Ovary Function in an Ovariectomized Rat Model via an Antioxidant Effect Antioxidants doi: 10.3390/antiox9070591 Authors: Seok Park Choi Lim Kim Kim Oxidative stress is one of the major etiologies of ovarian dysfunction, including premature ovarian failure (POF). Previous reports have demonstrated the therapeutic effects of human placenta-derived mesenchymal stem cells (PD-MSCs) in...
Antioxidants, Vol. 9, Pages 588: Dauricine Protects from LPS-Induced Bone Loss via the ROS/PP2A/NF-κB Axis in Osteoclasts Antioxidants doi: 10.3390/antiox9070588 Authors: Hyun-Jung Park Malihatosadat Gholam Zadeh Jae-Hee Suh Hye-Seon Choi Dauricine (DAC), an isoquinoline alkaloid, exhibits anti-inflammatory activity. We hypothesized that DAC may prevent the inflammatory bone loss induced by lipopolysaccharide (LPS). LPS-induced bone loss was decreased by DAC in female C57BL/6J...
Antioxidants, Vol. 9, Pages 592: Adeno-Associated Viral Transfer of Glyoxalase-1 Blunts Carbonyl and Oxidative Stresses in Hearts of Type 1 Diabetic Rats Antioxidants doi: 10.3390/antiox9070592 Authors: Alomar Al-Rubaish Al-Muhanna Al-Ali McMillan Singh Bidasee Accumulation of methylglyoxal (MG) arising from downregulation of its primary degrading enzyme glyoxalase-1 (Glo1) is an underlying cause of diabetic cardiomyopathy (DC). This study investigated if expressing...
Antioxidants, Vol. 9, Pages 589: Mitigating the Effects of Oxidative Sperm DNA Damage Antioxidants doi: 10.3390/antiox9070589 Authors: Pini Makloski Maruniak Schoolcraft Katz-Jaffe Sperm DNA damage is correlated with reduced embryo development and increased miscarriage risk, reducing successful conception. Given its links with oxidative stress, antioxidants have been investigated as a potential treatment, yet results are conflicting. Importantly, individual antioxidants...
Antioxidants, Vol. 9, Pages 593: Authentication of “Adelita” Raspberry Cultivar Based on Physical Properties, Antioxidant Activity and Volatile Profile Antioxidants doi: 10.3390/antiox9070593 Authors: Arantzazu Valdés García Salvador E. Maestre Pérez Mikita Butsko María Soledad Prats Moya Ana Beltrán Sanahuja Agricultural selection programmes are, today, working hard to obtain novel raspberry cultivars with higher nutritional and commercial quality. One of those cultivars...
Antioxidants, Vol. 9, Pages 587: Antioxidative Action of Ellagic Acid—A Kinetic DFT Study Antioxidants doi: 10.3390/antiox9070587 Authors: Jelena Tošović Urban Bren Although one can find numerous studies devoted to the investigation of antioxidative activity of ellagic acid (EA) in the scientific literature, the mechanisms of its action have not yet been fully clarified. Therefore, further kinetic studies are needed to understand its antioxidative capacity completely. This work aims...
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Arts, Vol. 9, Pages 74: Rethinking Collective Housing: A Case Study of Spatial Flexibility and Adaptability in Arturo Soria (Madrid, 1975) Arts doi: 10.3390/arts9030074 Authors: De Jorge Huertas This article presents an analysis of a collective housing project designed by the architects Emilia Bisquert Santiago, Carmen González Lobo, Jose Miguel de Prada Poole and Ricardo Aroca in the Arturo Soria neighbourhood in Madrid in 1975. This project is noteworthy for its architects’...
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Atmosphere, Vol. 11, Pages 722: Atmospheric Aerosol Distribution in 2016–2017 over the Eastern European Region Based on the GEOS-Chem Model Atmosphere doi: 10.3390/atmos11070722 Authors: Gennadi Milinevsky Natallia Miatselskaya Asen Grytsai Vassyl Danylevsky Andrey Bril Anatoli Chaikovsky Yulia Yukhymchuk Yuke Wang Anatoliy Liptuga Volodymyr Kyslyi Olena Turos Yuriy Serozhkin The spatial and temporal distributions of atmospheric aerosols have been simulated...
Atmosphere, Vol. 11, Pages 721: A Combined Citizen Science—Modelling Approach for NO2 Assessment in Torino Urban Agglomeration Atmosphere doi: 10.3390/atmos11070721 Authors: Matteo Bo Pietro Salizzoni Federica Pognant Roberto Mezzalama Marina Clerico The #CHEARIATIRA citizen science campaign was developed in February 2019 in Torino (western part of the Po Valley megacity region). The aim of the campaign was public engagement with measuring NO2 concentrations in an urban area...
Atmosphere, Vol. 11, Pages 720: Characterization and Source Apportionment of Fine Particles during a Heavy Pollution Episode over the Yangtze River Delta, China Atmosphere doi: 10.3390/atmos11070720 Authors: Li Xia Bin Zhu Honglei Wang Hanqing Kang Junlin An Regional-scale field observations of fine particles (PM2.5) were carried out at urban, suburban and regional background sites across the Yangtze River Delta (YRD) from 15–30 January 2015. The coefficients of...
Atmosphere, Vol. 11, Pages 719: A Collaborative Training Program to Assess Mercury Pollution from Gold Shops in Guyana’s Artisanal and Small-Scale Gold Mining Sector Atmosphere doi: 10.3390/atmos11070719 Authors: Brown Bandoo Agard Thom Gilhuys Mudireddy Eechampati Hasan Loving Seney Kiefer A three-phase, 11-day training program designed to monitor elemental mercury (Hg0) emissions originating from gold shops was conducted in Georgetown and Bartica,...
Atmosphere, Vol. 11, Pages 718: Exposure to Indoor Volatile Organic Compounds and Hypertension among Thin Film Transistor Liquid Crystal Display Workers Atmosphere doi: 10.3390/atmos11070718 Authors: Ta-Yuan Chang Kuei-Hung Huang Chiu-Shong Liu Bo-Ying Bao This cross-sectional study aimed to determine the concentration of indoor volatile organic compounds (VOCs) and to investigate the association between indoor VOCs exposure and the prevalence of hypertension among thin film...
Atmosphere, Vol. 11, Pages 717: Summer Monsoon Season Streamflow Variations in the Middle Yellow River since 1570 CE Inferred from Tree Rings of Pinus tabulaeformis Atmosphere doi: 10.3390/atmos11070717 Authors: Feng Chen Magdalena Opała-Owczarek Piotr Owczarek Youping Chen This study investigates the potential reconstruction of summer monsoon season streamflow variations in the middle reaches of the Yellow River from tree rings in the Qinling Mountains. The regional chronology...
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Behavioral Sciences, Vol. 10, Pages 112: The Fairytale Semantic Differential Technique: A Cross-Cultural Application Behavioral Sciences doi: 10.3390/bs10070112 Authors: Petrenko Mitina The “Fairytale Semantic Differential” method, in which the respondent assesses several fairytale characters according to a set of personal characteristics, is designed for individual psychological work with children 4–10 years old. Personality characteristics, according...
Behavioral Sciences, Vol. 10, Pages 111: Communication Adjustment in Engineering Professional and Student Project Meetings Behavioral Sciences doi: 10.3390/bs10070111 Authors: Kristina Nestsiarovich Dirk Pons Sid Becker Background: communication is important for project teams. There is a need to better understand how members respond to communication at project meetings, and how this affects the team roles the participants adopt. Methods: observational data were collected from (a)...
Behavioral Sciences, Vol. 10, Pages 110: The Endless Grief in Waiting: A Qualitative Study of the Relationship between Ambiguous Loss and Anticipatory Mourning amongst the Relatives of Missing Persons in Italy Behavioral Sciences doi: 10.3390/bs10070110 Authors: Ines Testoni Chiara Franco Lorenza Palazzo Erika Iacona Adriano Zamperini Michael Alexander Wieser This article presents the results of a qualitative study aiming to consider the relationship between ambiguous...
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Bioengineering, Vol. 7, Pages 71: Prospects and Challenges of Translational Corneal Bioprinting Bioengineering doi: 10.3390/bioengineering7030071 Authors: Fuest Yam Mehta Duarte Campos Corneal transplantation remains the ultimate treatment option for advanced stromal and endothelial disorders. Corneal tissue engineering has gained increasing interest in recent years, as it can bypass many complications of conventional corneal transplantation. The human cornea is an ideal...
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Biology, Vol. 9, Pages 154: Protective Effects of Bee Venom against Endotoxemia-Related Acute Kidney Injury in Mice Biology doi: 10.3390/biology9070154 Authors: Jung-Yeon Kim Sun-Jae Lee Young-In Maeng Jaechan Leem Kwan-Kyu Park Sepsis-associated acute kidney injury (AKI) is a leading cause of death in hospitalized patients worldwide. Despite decades of effort, there is no effective treatment for preventing the serious medical condition. Bee venom has long been used to treat...
Biology, Vol. 9, Pages 155: The Importance of Protein Phosphorylation for Signaling and Metabolism in Response to Diel Light Cycling and Nutrient Availability in a Marine Diatom Biology doi: 10.3390/biology9070155 Authors: Tan Smith Hixson Tan McCarthy Kustka Allen Diatoms are major contributors to global primary production and their populations in the modern oceans are affected by availability of iron, nitrogen, phosphate, silica, and other trace metals, vitamins,...
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Biomedicines, Vol. 8, Pages 196: Mitochondrial Membrane Potential Predicts 4-Hour Sperm Motility Biomedicines doi: 10.3390/biomedicines8070196 Authors: Angela Alamo Claudia De Luca Laura M. Mongioì Federica Barbagallo Rossella Cannarella Sandro La Vignera Aldo E. Calogero Rosita A. Condorelli The evaluation of conventional and biofunctional sperm parameters is of fundamental importance for assessing male reproductive function. Among these, sperm motility is one of...
Biomedicines, Vol. 8, Pages 195: Coarse-Grained Models of RNA Nanotubes for Large Time Scale Studies in Biomedical Applications Biomedicines doi: 10.3390/biomedicines8070195 Authors: Shyam Badu Sanjay Prabhakar Roderick Melnik In order to describe the physical properties of large time scale biological systems, coarse-grained models play an increasingly important role. In this paper we develop Coarse-Grained (CG) models for RNA nanotubes and then, by using Molecular Dynamics (MD)...
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Biomolecules, Vol. 10, Pages 1005: Myxovirus Resistance Protein 1 (MX1), a Novel HO-1 Interactor, Tilts the Balance of Endoplasmic Reticulum Stress towards Pro-Death Events in Prostate Cancer Biomolecules doi: 10.3390/biom10071005 Authors: Emiliano Ortiz Pablo Sanchis Juan Bizzotto Sofia Lage-Vickers Estefania Labanca Nora Navone Javier Cotignola Elba Vazquez Geraldine Gueron The inflammatory tumor microenvironment is a fertile niche accelerating prostate cancer...
Biomolecules, Vol. 10, Pages 1006: Optimized Ellagic Acid–Ca Pectinate Floating Beads for Gastroprotection against Indomethacin-Induced Gastric Injury in Rats Biomolecules doi: 10.3390/biom10071006 Authors: Alhakamy Badr-Eldin Ahmed Halwani Aldawsari A. El-Moselhy Anter Sharkawi Sultan Madkhali Bakhrebah Alomary Abdulaal Fahmy A peptic ulcer is an alimentary tract injury that leads to a mucosal defect reaching the submucosa. This work...
Biomolecules, Vol. 10, Pages 1004: Biochemical Characterization of Human Retroviral-Like Aspartic Protease 1 (ASPRV1) Biomolecules doi: 10.3390/biom10071004 Authors: Golda Mótyán Nagy Matúz Nagy Tőzsér The human retroviral-like aspartic protease 1 (ASPRV1) is a mammalian retroviral-like enzyme that catalyzes a critical proteolytic step during epidermal differentiation; therefore, it is also referred to as skin-specific aspartic protease (SASPase). Neutrophil granulocytes...
Biomolecules, Vol. 10, Pages 1003: Aldose Reductase Differential Inhibitors in Green Tea Biomolecules doi: 10.3390/biom10071003 Authors: Balestri Poli Pineschi Moschini Cappiello Mura Tuccinardi Del Corso Aldose reductase (AKR1B1), the first enzyme in the polyol pathway, is likely involved in the onset of diabetic complications. Differential inhibition of AKR1B1 has been proposed to counteract the damaging effects linked to the activity of the enzyme while...
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Biosensors, Vol. 10, Pages 73: Noninvasive Early Disease Diagnosis by Electronic-Nose and Related VOC-Detection Devices Biosensors doi: 10.3390/bios10070073 Authors: Wilson This editorial provides an overview and summary of recent research articles published in Biosensors journal, volumes 9 (2019) and 10 (2020), within the Special Issue “Noninvasive Early Disease Diagnosis”, which focused on recent sensors, biosensors, and clinical instruments developed for the noninvasive...
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Brain Sciences, Vol. 10, Pages 429: Where Sounds Occur Matters: Context Effects Influence Processing of Salient Vocalisations Brain Sciences doi: 10.3390/brainsci10070429 Authors: Atiqah Azhari Paola Rigo Marc H. Bornstein Gianluca Esposito The social context in which a salient human vocalisation is heard shapes the affective information it conveys. However, few studies have investigated how visual contextual cues lead to differential processing of such vocalisations. The prefrontal...
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Cancers, Vol. 12, Pages 1816: Characterization of Class-3 Semaphorin Receptors, Neuropilins and Plexins, as Therapeutic Targets in a Pan-Cancer Study Cancers doi: 10.3390/cancers12071816 Authors: Xiaoli Zhang Shuai Shao Lang Li Class-3 semaphorins (SEMA3s), initially characterized as axon guidance cues, have been recognized as key regulators for immune responses, angiogenesis, tumorigenesis and drug responses. The functions of SEMA3s are attributed to the activation of downstream...
Cancers, Vol. 12, Pages 1817: Beyond IDH-Mutation: Emerging Molecular Diagnostic and Prognostic Features in Adult Diffuse Gliomas Cancers doi: 10.3390/cancers12071817 Authors: Kanish Mirchia Timothy E. Richardson Diffuse gliomas are among the most common adult central nervous system tumors with an annual incidence of more than 16,000 cases in the United States. Until very recently, the diagnosis of these tumors was based solely on morphologic features, however, with the publication...
Cancers, Vol. 12, Pages 1814: Human Prostate Cancer is Characterized by an Increase in Urea Cycle Metabolites Cancers doi: 10.3390/cancers12071814 Authors: Shao Franko Heni Hennenlotter Hoene Hu Liu Zhao Wang Birkenfeld Todenhöfer Stenzl Peter Häring Lehmann Xu Lutz Despite it being the most common incident of cancer among men, the pathophysiological mechanisms contributing to prostate cancer (PCa) are still poorly understood....
Cancers, Vol. 12, Pages 1811: Proliferative Classification of Intracranially Injected HER2-positive Breast Cancer Cell Lines Cancers doi: 10.3390/cancers12071811 Authors: Yuka Kuroiwa Jun Nakayama Chihiro Adachi Takafumi Inoue Shinya Watanabe Kentaro Semba HER2 is overexpressed in 25–30% of breast cancers, and approximately 30% of HER2-positive breast cancers metastasize to the brain. Although the incidence of brain metastasis in HER2-positive breast cancer is...
Cancers, Vol. 12, Pages 1813: The Nucleolus and PARP1 in Cancer Biology Cancers doi: 10.3390/cancers12071813 Authors: Marina Engbrecht Aswin Mangerich The nucleolus has been known for a long time to fulfill crucial functions in ribosome biogenesis, of which cancer cells can become addicted to in order to produce sufficient amounts of proteins for cell proliferation. Recently, the nucleolus has emerged as a central regulatory hub in many other cancer-relevant processes, including stress...
Cancers, Vol. 12, Pages 1810: Aetiology of Myeloproliferative Neoplasms Cancers doi: 10.3390/cancers12071810 Authors: Mary Frances McMullin Lesley Ann Anderson Myeloproliferative neoplasms (MPNs) have estimated annual incidence rates for polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis of 0.84, 1.03, and 0.47 per 100,000. Prevalence is much higher, particularly for PV and ET, as mortality rates are relatively low. Patients are often concerned about...
Cancers, Vol. 12, Pages 1812: Bone, a Secondary Growth Site of Breast and Prostate Carcinomas: Role of Osteocytes Cancers doi: 10.3390/cancers12071812 Authors: Paola Maroni Paola Bendinelli Bone is the primarily preferred site for breast and prostate cancer to metastasize. Bone metastases are responsible for most deaths related to breast and prostate cancer. The bone’s particular microenvironment makes it conducive for the growth of cancer cells. Studies on bone metastasis...
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