Related Articles Neck CT angiography examinations for pediatric oropharyngeal trauma: diagnostic yield and proposal of a new targeted technique. Pediatr Radiol. 2020 Jul 03;: Authors: Choi JJ, Burton CS, Danehy AR, Voss SD Abstract BACKGROUND: Neck computed tomography (CT) angiography is commonly ordered for pediatric patients with soft palate trauma to exclude vascular injury. Debate exists regarding what type of imaging is indicated in this...
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Biomarkers for HER2-positive metastatic breast cancer: Beyond hormone receptors. Cancer Treat Rev. 2020 Jun 24;88:102064 Authors: Dieci MV, Miglietta F, Griguolo G, Guarneri V Abstract The overexpression of human epidermal growth factor receptor-2 (HER2) results in a biologically and clinically aggressive breast cancer (BC) subtype. Since the introduction of anti-HER2 targeted agents, survival rates of patients with HER2-positive metastatic...
Related Articles Resumption of Trastuzumab in Patients With Disease Recurrence After (Neo-) Adjuvant Anti-HER2-therapy in Patients With HER2-positive Breast Cancer. Anticancer Res. 2020 Jul;40(7):3973-3981 Authors: Hanker LC, FÖrster F, SchrÖder J, Grafe A, Hitschold T, Hesse T, Lattrich CR, Rody A Abstract BACKGROUND/AIM: HER2-positive breast cancers eventually relapse in about one third of patients. Is anti-HER2-directed therapy with Herceptin®...
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Related Articles Development and accuracy of a hearing screening application. Braz J Otorhinolaryngol. 2020 May 05;: Authors: Bauer MA, Sales A, Teixeira AR, Morsch P, Lessa AH, Bós ÂJG Abstract INTRODUCTION: Hearing impairment, or hearing loss, can be caused by several factors and the implications vary according to the type, degree, cause and age of occurrence. Hearing screening should be a common procedure, allowing the pre-clinical identification...
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Expression of collagen type III in healing tympanic membrane. Int J Pediatr Otorhinolaryngol. 2020 Jun 24;136:110196 Authors: Makuszewska M, Bonda T, Cieślińska M, Bialuk I, Winnicka MM, Niemczyk K Abstract OBJECTIVES: Type III collagen plays significant role in skin wound healing, forming provisional matrix guiding the inflammatory cells and fibroblasts into the wound site. Our preliminary study performed on rat's tympanic membrane (TM) using...
3-year follow-up after balloon sinuplasty in children with chronic rhinosinusitis. Int J Pediatr Otorhinolaryngol. 2020 Jun 03;136:110084 Authors: Jia L, Cao C, Jing B, Zigai Z, Bin X, Xiaowei C, Lexi L, Jiren D, Yang Z, Yong F Abstract OBJECTIVE: Balloon sinuplasty could restore nasal sinus drainage and airflow, limiting the damages and lowering the risks. This study aimed to assess the 3-year clinical efficacy, safety, and satisfactory degree...
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Thalidomide use in the management of oromucosal disease: A 10-year review of safety and efficacy in 12 patients. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jun 17;: Authors: Harte MC, Saunsbury TA, Hodgson TA Abstract OBJECTIVE: Thalidomide is an effective systemic agent in the management of ulcerative oromucosal conditions. However, its clinical use is limited because of its known adverse effect profile, including teratogenicity,...
Real-time evaluation of swallowing in patients with oral cancers by using cine-magnetic resonance imaging based on T2-weighted sequences. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 May 26;: Authors: Tanaka T, Tanaka R, Yeung AWK, Bornstein MM, Nishimura S, Oda M, Habu M, Takahashi O, Yoshiga D, Sago T, Miyamoto I, Kodama M, Wakasugi-Sato N, Matsumoto-Takeda S, Joujima T, Miyamura Y, Morimoto Y Abstract OBJECTIVE: The aim of this...
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Lipopolysaccharide regulates thymic stromal lymphopoietin expression via TLR4/MAPK/Akt/NF-κB-signaling pathways in nasal fibroblasts: differential inhibitory effects of macrolide and corticosteroid. Int Forum Allergy Rhinol. 2020 Jul 05;: Authors: Kang JH, Yang HW, Park JH, Shin JM, Kim TH, Lee SH, Lee HM, Park IH Abstract BACKGROUND: Chronic rhinosinusitis (CRS) is an inflammatory disease of the sinonasal mucosa. Thymic stromal lymphopoietin...
Related Articles A randomized controlled trial on the efficacy of life review therapy targeting incurably ill cancer patients: do their informal caregivers benefit? Support Care Cancer. 2020 Jul 03;: Authors: Kleijn G, Lissenberg-Witte BI, Bohlmeijer ET, Willemsen V, Becker-Commissaris A, Eeltink CM, Bruynzeel AME, van der Vorst MJ, Cuijpers P, Verdonck-de Leeuw IM Abstract PURPOSE: Investigate whether Life Review Therapy and Memory Specificity...
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The serum amyloid A (SAA) gene family is highly conserved and encodes acute phase proteins that are upregulated in response to inflammatory triggers. Over the years, a considerable amount of literature has been published attributing a wide range of biological effects to SAAs such as leukocyte recruitment, cytokine and chemokine expression and induction of matrix metalloproteinases. Furthermore, SAAs have also been linked to protumorigenic, proatherogenic and anti-inflammatory effects. Here, we investigated...
Objective. To investigate prognostic values of serum biomarkers of soluble intercellular adhesion molecule 1 (sICAM-1), macrophage migration inhibitor factor (MIF), interleukin 1β (IL-1β), and soluble urokinase plasminogen activator receptor (su-PAR) in patients with acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF). Methods. From August 2017 to November 2019, 122 consecutive IPF patients treated in our center were classified as stable IPF and AE-IPF based on the newly published international...
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1,2,4-Triazole A Privileged Scaffold For The Development Of Potent Antifungal Agents-A Brief Review.
1,2,4-Triazole A Privileged Scaffold For The Development Of Potent Antifungal Agents-A Brief Review. Curr Top Med Chem. 2020 Jul 04;: Authors: Tratrat C Abstract Over the past decades, a dramatically tremendous rise in invasive fungal infection diseases attributed to the yeast Candida albicans in immunocompromised individuals poses a serious challenging issue. Another alarming concern is the emergence of multi-drug resistant pathogens to the...
An Update on Staphylococcus aureus NorA Efflux Pump Inhibitors. Curr Top Med Chem. 2020 Jul 04;: Authors: Monteiro KLC, de Aquino TM, Mendonça Junior FJB Abstract BACKGROUND: Methicillin-resistant and vancomycin-resistant Staphylococcus aureus are pathogens causing severe infectious diseases that pose real public health threats problems worldwide. In S. aureus, the most efficient multidrugresistant system is the NorA efflux pump. For this reason,...
Shape-based Machine Learning Models for the potential Novel COVID-19 protease inhibitors assisted by Molecular Dynamics Simulation. Curr Top Med Chem. 2020 Jul 04;: Authors: Khandelwal R, Nayarisseri A, Madhavi M, Selvaraj C, Panwar U, Sharma K, Hussain T, Singh SK Abstract BACKGROUND: The vast geographical expansion of novel coronavirus and an increasing number of COVID-19 affected cases has overwhelmed health and public health services. AI...
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Australia's national COVID-19 primary care response. Med J Aust. 2020 Jul 04;: Authors: Desborough J, Hall Dykgraaf S, de Toca L, Davis S, Roberts L, Kelaher C, Kidd M PMID: 32623740 [PubMed - as supplied by publisher]
Reusing N95 (or P2) masks: current evidence and urgent research questions. Med J Aust. 2020 Jul 04;: Authors: Branley JM, Polkinghorne A, Gilbert GL PMID: 32623732 [PubMed - as supplied by publisher]
Genetic analysis and long-term treatment monitoring of 11 children with glycogen storage disease type IIIa. J Pediatr Endocrinol Metab. 2020 Jul 05;: Authors: Du C, Wei H, Zhang M, Hu M, Li Z, Zhang C, Luo X, Liang Y Abstract Objectives To investigate the clinical and genetic characteristics of children with glycogen storage disease type IIIa (GSD IIIa) and to explore the muscle involvement and manifestations of GSD IIIa patients. Methods...
The Risk of Respiratory Tract Infections in Psoriasis Patients Treated With IL-23-pathway Inhibiting Biologics: A Meta-Estimate of Pivotal Trials Relevant to Decision-Making During the COVID-19 Pandemic. J Am Acad Dermatol. 2020 Jul 02;: Authors: Syed MN, Shin DB, Wan MT, Winthrop KL, Gelfand JM PMID: 32622891 [PubMed - as supplied by publisher]
Reply to: "Do IL-17 Inhibitors Increase Risk of Respiratory Tract Infections?" J Am Acad Dermatol. 2020 Jul 01;: Authors: Wan MT, Shin DB, Winthrop KL, Gelfand JM PMID: 32622146 [PubMed - as supplied by publisher]
Do IL-17 Inhibitors Increase Risk of Respiratory Tract Infections? J Am Acad Dermatol. 2020 Jul 01;: Authors: Blauvelt A, Ehst BD PMID: 32622137 [PubMed - as supplied by publisher]
Maternal respiratory infections in early pregnancy increases the risk of type 1 diabetes. Pediatr Diabetes. 2020 Jul 04;: Authors: Bélteky M, Wahlberg J, Ludvigsson J Abstract BACKGROUND/OBJECTIVE: Is exposure to maternal infections and use of antibiotics in the prenatal period associated with increased risk of T1D, regardless of genetic risk? METHODS: Data on infections and use of antibiotics during pregnancy were collected...
Related Articles Severe Acute Respiratory Syndrome Coronavirus 2 Prevalence, Seroprevalence, and Exposure Among Evacuees from Wuhan, China, 2020. Emerg Infect Dis. 2020 Jul 03;26(9): Authors: Hallowell BD, Carlson CM, Jacobs JR, Pomeroy M, Steinberg J, Tenforde M, McDonald E, Foster L, Feldstein LR, Rolfes MA, Haynes A, Abedi GR, Odongo GS, Saruwatari K, Rider EC, Douville G, Bhakta N, Maniatis P, Lindstrom S, Thornburg NJ, Lu X, Whitaker BL, Kamili S, Sakthivel...
Related Articles The role of NTHi colonization and infection in the pathogenesis of neutrophilic asthma. Respir Res. 2020 Jul 03;21(1):170 Authors: Zhang J, Zhu Z, Zuo X, Pan H, Gu Y, Yuan Y, Wang G, Wang S, Zheng R, Liu Z, Wang F, Zheng J Abstract Asthma is a complex heterogeneous disease. The neutrophilic subtypes of asthma are described as persistent, more severe and corticosteroid-resistant, with higher hospitalization and mortality...
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Bencycloquidium bromide nasal spray is effective and safe for persistent allergic rhinitis: a phase III, multicenter, randomized, double-blinded, placebo-controlled clinical trial. Eur Arch Otorhinolaryngol. 2020 Jul 04;: Authors: Jiang Z, Xiao H, Liu S, He G, Hu G, Zhang X, Zhang Q, Chen J, Lin C, Liang J, Guo M, Xiao X, Xue W, Dong P, Huang Y, Lian Z, Tan G, He J, Pan Y, Meng J Abstract PURPOSE: To investigate the efficacy and safety of bencycloquidium...
Mon Jul 06, 2020 15:00
Nasal reconstructive surgery for vasculitis affecting the nose: our two-centre international experience. Eur Arch Otorhinolaryngol. 2020 Jul 04;: Authors: Unadkat SN, Pendolino AL, Kwame I, Swift A, Pusey C, Gantous A, Andrews PJ Abstract PURPOSE: To recommend an international multidisciplinary medical and surgical algorithm of treatment in nasal vasculitis, which will create a more streamlined approach. METHODS: A two-centre, international...
Mon Jul 06, 2020 15:00
Proton pencil-beam scanning radiotherapy in the treatment of nasopharyngeal cancer: dosimetric parameters and 2-year results. Eur Arch Otorhinolaryngol. 2020 Jul 04;: Authors: Jiří K, Vladimír V, Michal A, Matěj N, Silvia S, Pavel V, Kateřina D, Jana P, Barbora O, Eliška R, Petr L, Matěj P, Alexander G, Jozef R Abstract OBJECTIVES: Patients with nasopharyngeal cancer are candidates for proton radiotherapy due to large and comprehensive target...
Mon Jul 06, 2020 15:00
Intracapsular coblation tonsillecttomy versus extracapsular coblation tonsillectomy: a systematic review and a meta-analysis. Eur Arch Otorhinolaryngol. 2020 Jul 04;: Authors: Daskalakis D, Tsetsos N, Karagergou S, Goudakos J, Markou K, Karkos P Abstract PURPOSE: To assess all available data regarding the comparative benefit of intracapsular coblation tonsillectomy (ICT) versus extracapsular coblation tonsillectomy (ECT) in children. ...
Mon Jul 06, 2020 15:00
The bacteriology of recurrent acute exacerbations of chronic rhinosinusitis: a longitudinal analysis. Eur Arch Otorhinolaryngol. 2020 Jul 04;: Authors: Yaniv D, Stern D, Vainer I, Ben Zvi H, Yahav D, Soudry E Abstract PURPOSE: The purpose of this study was to describe the microbiology of recurrent acute exacerbations of chronic rhinosinusitis over time. METHODS: Retrospective review of patients with recurrent acute exacerbations of...
Mon Jul 06, 2020 15:00
Related Articles Personal protective equipment for ENT activity during COVID-19 pandemic. Eur Arch Otorhinolaryngol. 2020 Jul 03;: Authors: Farneti P, Sorace F, Tasca I Abstract BACKGROUND: In the COVID-19 era physicians have to face with need to perform office procedures maintaining the maximum safety for both the patient and the Doctor himself. The purpose of this paper was to suggest some equipment useful to perform outpatient visits in an...
Mon Jul 06, 2020 15:00
Related Articles Improving screening for physical impairments and access to early physiotherapy after neck dissection surgery: a translational controlled trial. Eur Arch Otorhinolaryngol. 2020 Jul 03;: Authors: McGarvey AC, Osmotherly PG, Hoffman GR, Hall A Abstract PURPOSE: Lack of routine screening for a range of physical impairments that can result after neck dissection (ND) may hinder physiotherapy referral and treatment. The purpose of...
Mon Jul 06, 2020 15:00
Related Articles Minimally invasive procedure for diagnosis and treatment of vallecular cysts in children: review of 156 cases. Eur Arch Otorhinolaryngol. 2020 Jul 03;: Authors: Wang GX, Zhang FZ, Zhao J, Wang H, Li HB, Wang XM, Zhang J, Ni X Abstract PURPOSE: Vallecular cyst is an uncommon but potentially life-threatening disease. The aim of this study was to review the presentation, evaluation, and treatment of vallecular cysts in children....
Mon Jul 06, 2020 15:00
Related Articles Helicobacter pylori gastric infection in patients with laryngeal cancer and chronic laryngitis. Eur Arch Otorhinolaryngol. 2020 Jul 03;: Authors: Pajić Matić I, Matić I, Maslovara S, Veselski K, Stojadinović T, Vučković I Abstract BACKGROUND: The purpose of this study was to investigate the pathohistological status of mucous lining infected with Helicobacte pylori as the possible cause of chronic laryngitis and laryngeal carcinoma....
Mon Jul 06, 2020 15:00
Related Articles How applicable is the TNM 8 staging for human papillomavirus (HPV) related oropharyngeal squamous cell carcinoma (OPSCC) to a UK population of 106 patients? : A cohort comparison of the TNM 7 and TNM8 staging systems for HPV positive oropharyngeal cancer in a UK population. Eur Arch Otorhinolaryngol. 2020 Jul 03;: Authors: Bradish T, Fisher H, Paleri V, Robinson M, Meikle D, Kelly C, O'Hara J Abstract PURPOSE: TNM8 introduced...
Mon Jul 06, 2020 15:00
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Giant Vertebral Artery Aneurysm: A Rare Cause of Respiratory Failure and Swallowing Disorder. Neurochirurgie. 2020 Jul 02;: Authors: Soh Y, Park BJ PMID: 32623055 [PubMed - as supplied by publisher]
Related Articles Inter-individual variation of bolus properties in triggering swallowing during chewing in healthy humans. J Oral Rehabil. 2020 Jul 03;: Authors: Maeda R, Takei E, Ito K, Magara J, Tsujimura T, Inoue M Abstract BACKGROUND: There is a wide variation of chewing behaviors even in healthy humans. The present study was aimed to clarify how the rheological properties of the bolus during chewing is different among individuals. We also...
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Technical Consideration of Interlaminar Approach in the Lumbar Disc Herniation. World Neurosurg. 2020 Jul 02;: Authors: Chen KT, Tseng C, Sun LW, Chang KS, Chen CM Abstract With the evolution of endoscopic instruments and techniques, full-endoscopic spine surgery(FESS) has attracted more attention worldwide in recent years. At the initial stage, surgeons conducted endoscopic lumbar discectomy by the transforaminal approach. Then, interlaminar...
Late onset Post-traumatic Spinal Cord Herniation as a Rare and an Overlooked Cause of Late Neurological Deterioration following Penetrating Injury to The Thoracic Spine: A Case Report and Review of Literature. World Neurosurg. 2020 Jul 02;: Authors: Mohamed E, Christos G PMID: 32622921 [PubMed - as supplied by publisher]
Decision Analysis in Quest of the Ideal Treatment in Adult Spinal Deformity adjusted for Minimum Clinically Important Difference. World Neurosurg. 2020 Jul 01;: Authors: Acaroglu E, Yuksel S, Ates C, Ayhan S, Bahadir S, Nabi V, Vila-Casedemunt A, Sanchez Perez-Grueso FJ, Obeid I, European Spine Study Group Abstract BACKGROUND: Surgery (S) appears to yield better results in adult spinal deformity treatment when fixed minimum clinically important...
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