Cancers, Vol. 12, Pages 1809: Identification of GSN and LAMC2 as Key Prognostic Genes of Bladder Cancer by Integrated Bioinformatics Analysis Cancers doi: 10.3390/cancers12071809 Authors: Jia-Lian Yang Charles C.N. Wang Jia-Hua Cai Che-Yi Chou Yu-Chao Lin Chin-Chuan Hung Bladder cancer is a common malignancy with mechanisms of pathogenesis and progression. This study aimed to identify the prognostic hub genes, which are the central modulators to regulate the progression...
Mon Jul 06, 2020 03:00
Cancers, Vol. 12, Pages 1815: The Premature Senescence in Breast Cancer Treatment Strategy Cancers doi: 10.3390/cancers12071815 Authors: Małgorzata Milczarek Cellular senescence is a permanent blockade of cell proliferation. In response to therapy-induced stress, cancer cells undergo apoptosis or premature senescence. In apoptosis-resistant cancer cells or at lower doses of anticancer drugs, therapy-induced stress leads to premature senescence. The role of this senescence in cancer treatment...
Mon Jul 06, 2020 03:00
Cancers, Vol. 12, Pages 1807: Harnessing NK Cell Checkpoint-Modulating Immunotherapies Cancers doi: 10.3390/cancers12071807 Authors: Sachin Kumar Singh Chauhan Ulrike Koehl Stephan Kloess During the host immune response, the precise balance of the immune system, regulated by immune checkpoint, is required to avoid infection and cancer. These immune checkpoints are the mainstream regulator of the immune response and are crucial for self-tolerance. During the last decade, various...
Mon Jul 06, 2020 03:00
Cancers, Vol. 12, Pages 1808: Genomic and Transcriptomic Characterisation of Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Cancers doi: 10.3390/cancers12071808 Authors: Sinead Toomey Jillian Gunther Aoife Carr David C. Weksberg Valentina Thomas Manuela Salvucci Orna Bacon El-Masry Sherif Joanna Fay Elaine W. Kay Katherine M. Sheehan Deborah A. McNamara Keith L Sanders Geena Mathew Oscar S. Breathnach Liam Grogan Patrick...
Mon Jul 06, 2020 03:00
Cancers, Vol. 12, Pages 1806: Improved Diagnostic Imaging of Brain Tumors by Multimodal Microscopy and Deep Learning Cancers doi: 10.3390/cancers12071806 Authors: Johanna Gesperger Antonia Lichtenegger Thomas Roetzer Matthias Salas Pablo Eugui Danielle J. Harper Conrad W. Merkle Marco Augustin Barbara Kiesel Petra A. Mercea Georg Widhalm Bernhard Baumann Adelheid Woehrer Fluorescence-guided surgery is a state-of-the-art approach for intraoperative...
Mon Jul 06, 2020 03:00
Cancers, Vol. 12, Pages 1804: ALK-Brain Prognostic Index—Preliminary Study of a Prognostic Tool for Patients with ALK-Rearranged, Non-small Cell Lung Cancer and Brain Metastases Cancers doi: 10.3390/cancers12071804 Authors: Georgios Tsakonas Caroline Kamali Luigi De Petris Signe Friesland Rolf Lewensohn Simon Ekman Background: Disease-specific Graded Prognostic Assessment (DS-GPA) is the most validated prognostic tool for patients with brain metastasized lung cancer. The...
Mon Jul 06, 2020 03:00
Cancers, Vol. 12, Pages 1803: Epitope Mapping and Computational Analysis of Anti-HPV16 E6 and E7 Antibodies in Single-Chain Format for Clinical Development as Antitumor Drugs Cancers doi: 10.3390/cancers12071803 Authors: Carla Amici Maria Gabriella Donà Barbara Chirullo Paola Di Bonito Luisa Accardi Human Papillomavirus 16-associated cancer, affecting primarily the uterine cervix but, increasingly, other body districts, including the head–neck area, will long be...
Mon Jul 06, 2020 03:00
Cancers, Vol. 12, Pages 1805: Risk of Liver Cirrhosis and Hepatocellular Carcinoma after Fontan Operation: A Need for Surveillance Cancers doi: 10.3390/cancers12071805 Authors: Jun Sik Yoon Dong Ho Lee Eun Ju Cho Mi Kyoung Song Young Hun Choi Gi Beom Kim Yun Bin Lee Jeong-Hoon Lee Su Jong Yu Haeryoung Kim Yoon Jun Kim Jung-Hwan Yoon Eun Jung Bae Liver cirrhosis and hepatocellular carcinoma (HCC) are serious late complications that can occur after the...
Mon Jul 06, 2020 03:00
Cells, Vol. 9, Pages 1627: Cell-Type Targeted NF-kappaB Inhibition for the Treatment of Inflammatory Diseases Cells doi: 10.3390/cells9071627 Authors: Bettina Sehnert Harald Burkhardt Stefan Dübel Reinhard E. Voll Deregulated NF-k activation is not only involved in cancer but also contributes to the pathogenesis of chronic inflammatory diseases like rheumatoid arthritis (RA) and multiple sclerosis (MS). Ideally, therapeutic NF-KappaB inhibition should only take place in those...
Mon Jul 06, 2020 03:00
Cells, Vol. 9, Pages 1625: Mertk Interacts with Tim-4 to Enhance Tim-4-Mediated Efferocytosis Cells doi: 10.3390/cells9071625 Authors: Byeongjin Moon Juyeon Lee Sang-Ah Lee Chanhyuk Min Hyunji Moon Deokhwan Kim Susumin Yang Heera Moon Jaeseon Jeon Young-Eun Joo Daeho Park Apoptotic cells expressing phosphatidylserine (PS) on their cell surface are directly or indirectly recognized by phagocytes through PS-binding proteins. The PS-binding protein Tim-4 secures...
Mon Jul 06, 2020 03:00
Cells, Vol. 9, Pages 1626: Development of Artificial Plasma Membranes Derived Nanovesicles Suitable for Drugs Encapsulation Cells doi: 10.3390/cells9071626 Authors: Martinelli Gabriele Dini Carriero Bresciani Slivinschi Dei Giudici Zanoletti Manai Paolillo Schinelli Azzalin Comincini Extracellular vesicles (EVs) are considered as promising nanoparticle theranostic tools in many pathological contexts. The increasing clinical employment...
Mon Jul 06, 2020 03:00
Cells, Vol. 9, Pages 1624: Kinase-Independent Functions of MASTL in Cancer: A New Perspective on MASTL Targeting Cells doi: 10.3390/cells9071624 Authors: James Ronald William Conway Elisa Närvä Maria Emilia Taskinen Johanna Ivaska Microtubule-associated serine/threonine kinase-like (MASTL; Greatwall) is a well-characterized kinase, whose catalytic role has been extensively studied in relation to cell-cycle acceleration. Importantly, MASTL has been implicated to play a substantial...
Mon Jul 06, 2020 03:00
Cells, Vol. 9, Pages 1623: Modeling of Cell Nuclear Mechanics: Classes, Components, and Applications
Cells, Vol. 9, Pages 1623: Modeling of Cell Nuclear Mechanics: Classes, Components, and Applications Cells doi: 10.3390/cells9071623 Authors: Chad M. Hobson Andrew D. Stephens Cell nuclei are paramount for both cellular function and mechanical stability. These two roles of nuclei are intertwined as altered mechanical properties of nuclei are associated with altered cell behavior and disease. To further understand the mechanical properties of cell nuclei and guide future experiments,...
Mon Jul 06, 2020 03:00
Cells, Vol. 9, Pages 1622: A Concise Review on Tissue Engineered Artificial Skin Grafts for Chronic Wound Treatment: Can We Reconstruct Functional Skin Tissue In Vitro? Cells doi: 10.3390/cells9071622 Authors: Agata Przekora Chronic wounds occur as a consequence of a prolonged inflammatory phase during the healing process, which precludes skin regeneration. Typical treatment for chronic wounds includes application of autografts, allografts collected from cadaver, and topical delivery...
Mon Jul 06, 2020 03:00
Cells, Vol. 9, Pages 1621: miR-7 Regulates GLP-1-Mediated Insulin Release by Targeting β-Arrestin 1 Cells doi: 10.3390/cells9071621 Authors: Alessandro Matarese Jessica Gambardella Angela Lombardi Xujun Wang Gaetano Santulli Glucagon-like peptide-1 (GLP-1) has been shown to potentiate glucose-stimulated insulin secretion binding GLP-1 receptor on pancreatic β cells. β-arrestin 1 (βARR1) is known to regulate the desensitization of GLP-1 receptor....
Mon Jul 06, 2020 03:00
Chemosensors, Vol. 8, Pages 51: Macrocyclic Arenes Functionalized with BODIPY: Rising Stars among Chemosensors and Smart Materials Chemosensors doi: 10.3390/chemosensors8030051 Authors: Jianjun Huang Yuyu Fang Wim Dehaen Macrocycles play a crucial role in supramolecular chemistry and the family of macrocyclic arenes represents one of the most important types of hosts. Among them, calixarenes, resorcinarenes and pillararenes are the most commonly encountered macrocyclic arenes,...
Mon Jul 06, 2020 03:00
Dentistry Journal, Vol. 8, Pages 71: Suppressive Effects of Hainosan (Painongsan) against Biofilm Production by Streptococcus mutans Dentistry Journal doi: 10.3390/dj8030071 Authors: Minami Takase Taira Makino Streptococcus mutans, a bacterium that causes dental plaques, forms a biofilm on tooth surfaces. This biofilm can cause gingivitis by stimulating the gingival margin. However, there is no established treatment for biofilm removal. Hainosan (Painongsan), a traditional...
Mon Jul 06, 2020 03:00
Diagnostics, Vol. 10, Pages 460: Diagnostic Roles of Immunohistochemistry in Thymic Tumors: Differentiation between Thymic Carcinoma and Thymoma Diagnostics doi: 10.3390/diagnostics10070460 Authors: Jeong Pyo Kim Kang Background: The present study aims to evaluate the diagnostic roles of various immunohistochemical (IHC) markers in thymic tumors, including thymic carcinoma (TC) and thymoma (TM). Methods: Eligible studies were obtained by searching the PubMed databases and...
Mon Jul 06, 2020 03:00
Diagnostics, Vol. 10, Pages 459: Influence of Biopsy Technique on Molecular Genetic Tumor Characterization in Non-Small Cell Lung Cancer—The Prospective, Randomized, Single-Blinded, Multicenter PROFILER Study Protocol Diagnostics doi: 10.3390/diagnostics10070459 Authors: Maik Haentschel Michael Boeckeler Irina Bonzheim Florian Schimmele Werner Spengler Franz Stanzel Christoph Petermann Kaid Darwiche Lars Hagmeyer Reinhard Buettner Markus Tiemann Hans-Ulrich...
Mon Jul 06, 2020 03:00
Diagnostics, Vol. 10, Pages 458: Reply to “Missing Skeletal Muscle Metastases of Papillary Thyroid Carcinoma” Diagnostics doi: 10.3390/diagnostics10070458 Authors: Liviu Hitu Calin Cainap Dragos Apostu Katalin Gabora Eduard-Alexandru Bonci Marius Badan Alexandru Mester Andra Piciu Mr [...]
Mon Jul 06, 2020 03:00
Diagnostics, Vol. 10, Pages 457: Missing Skeletal Muscle Metastases of Papillary Thyroid Carcinoma Diagnostics doi: 10.3390/diagnostics10070457 Authors: Leszek Herbowski With regard to several important gaps in the work “Skeletal Muscle Metastasis in Papillary Thyroid Microcarcinoma Evaluated by F18-FDG PET/CT”, it seems necessary to clarify and extend some key issues in this text [...]
Mon Jul 06, 2020 03:00
Diversity, Vol. 12, Pages 268: Spatial Segregation between Red Foxes (Vulpes vulpes), European Wildcats (Felis silvestris) and Domestic Cats (Felis catus) in Pastures in a Livestock Area of Northern Spain Diversity doi: 10.3390/d12070268 Authors: Rodríguez Urra Jubete Román Revilla Palomares Red foxes, European wildcats and domestic cats share cattle pastures for hunting in La Pernía Valley, northern Spain. To understand the mechanisms that allow the coexistence...
Mon Jul 06, 2020 03:00
Foods, Vol. 9, Pages 887: Nutritional Value and Antimicrobial Activity of Pittosporum angustifolium (Gumby Gumby), an Australian Indigenous Plant Foods doi: 10.3390/foods9070887 Authors: Anh Dao Thi Phan Mridusmita Chaliha Hung Trieu Hong Ujang Tinggi Michael E. Netzel Yasmina Sultanbawa The indigenous endemic plant P. angustifolium has received attention for nutraceutical and therapeutic applications in Australia. This study investigates for the first time the nutritional...
Mon Jul 06, 2020 03:00
Foods, Vol. 9, Pages 886: Renewing Traditions: A Sensory and Chemical Characterisation of Mexican Pigmented Corn Beers Foods doi: 10.3390/foods9070886 Authors: Romero-Medina Estarrón-Espinosa Verde-Calvo Lelièvre-Desmas Escalona-Buendía This study was undertaken to explore how the use of pigmented corn as brewing ingredient influences the sensory profile of craft beers, by using both sensory and chemical analyses. Six pigmented corn and barley beers were brewed and then...
Mon Jul 06, 2020 03:00
Foods, Vol. 9, Pages 885: Nutritional Value of the Larvae of the Alien Invasive Wasp Vespa velutina nigrithorax and Amino Acid Composition of the Larval Saliva Foods doi: 10.3390/foods9070885 Authors: Jeong Kim Kim Nam Hahn Choi The systematic investigations on the value of social wasps as a food resource are deficient, in spite of the long history of the utilization of social wasps as food and pharmaceutical bioresources. Vespa velutina nigrithorax is an invasive...
Mon Jul 06, 2020 03:00
Foods, Vol. 9, Pages 883: Optimization of the Red Tilapia (Oreochromis spp.) Viscera Hydrolysis for Obtaining Iron-Binding Peptides and Evaluation of In Vitro Iron Bioavailability Foods doi: 10.3390/foods9070883 Authors: Leidy J. Gómez Nathalia A. Gómez José E. Zapata Gabriel López-García Antonio Cilla Amparo Alegría Iron deficiencies continue to cause significant health problems in vulnerable populations. A good strategy to combat mineral deficiency includes fortification...
Mon Jul 06, 2020 03:00
Foods, Vol. 9, Pages 884: Determination of Organosulfides from Onion Oil Foods doi: 10.3390/foods9070884 Authors: Cantrell Seale Arispe McDougal Qualitative and semi-quantitative analysis of organosulfides extracted from oil obtained by steam distillation of yellow onions was performed by gas chromatography-mass spectrometry (GC-MS). The extraction efficiency of organosulfides from onion oil was evaluated across four solvents: dichloromethane; diethyl ether; n-pentane; and...
Mon Jul 06, 2020 03:00
Healthcare, Vol. 8, Pages 199: Psychological Capital Mediates the Association between Job Stress and Burnout of among Korean Psychiatric Nurses Healthcare doi: 10.3390/healthcare8030199 Authors: Kim Kweon This study examined the mediating effect of psychological capital in the relationship between job stress and burnout of psychiatric nurses. The participants were 108 psychiatric nurses working in three psychiatric hospitals located in South Korea. Data were collected from 10 August...
Mon Jul 06, 2020 03:00
IJERPH, Vol. 17, Pages 4878: Epigenetic Basis of Lead-Induced Neurological Disorders International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17134878 Authors: Tian Wang Jie Zhang Yi Xu Environmental lead (Pb) exposure is closely associated with pathogenesis of a range of neurological disorders, including Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), attention deficit/hyperactivity disorder...
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IJERPH, Vol. 17, Pages 4879: Environmental Exposures and Hearing Loss International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17134879 Authors: Rita Rosati Samson Jamesdaniel Pollutants that contaminate the natural or built environment adversely affect the health of living organisms. Although exposure to many of them could be avoided or minimized by careful preventive measures, it is impossible to totally avoid exposure to all pollutants. Ototraumatic...
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IJERPH, Vol. 17, Pages 4876: A New Nasal Restriction Device Called FeelBreathe® Improves Breathing Patterns in Chronic Obstructive Pulmonary Disease Patients during Exercise International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17134876 Authors: José L. Gonzalez-Montesinos Aurelio Arnedillo Jorge R. Fernandez-Santos Carmen Vaz-Pardal Pelayo A. García José Castro-Piñero Jesús G. Ponce-González A device called FeelBreathe (FB)® was...
Mon Jul 06, 2020 03:00
IJERPH, Vol. 17, Pages 4877: The Outcome and Implications of Public Precautionary Measures in Taiwan–Declining Respiratory Disease Cases in the COVID-19 Pandemic International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17134877 Authors: Chih-Chia Hsieh Chih-Hao Lin William Yu Chung Wang David J. Pauleen Jengchung Victor Chen With the rapid development of the COVID-19 pandemic, countries are trying to cope with increasing medical demands, and, at...
Mon Jul 06, 2020 03:00
IJERPH, Vol. 17, Pages 4872: Cluster-Based Analysis of Infectious Disease Occurrences Using Tensor Decomposition: A Case Study of South Korea International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17134872 Authors: Seungwon Jung Jaeuk Moon Eenjun Hwang For a long time, various epidemics, such as lower respiratory infections and diarrheal diseases, have caused serious social losses and costs. Various methods for analyzing infectious disease occurrences...
Mon Jul 06, 2020 03:00
IJERPH, Vol. 17, Pages 4870: Environmental Risks Perception Among Citizens Living Near Industrial Plants: A Cross-Sectional Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17134870 Authors: Dettori Pittaluga Busonera Gugliotta Azara Piana Arghittu Castiglia The present work is a cross-sectional study aimed at assessing the risk perception and evaluating the community outrage linked to environmental factors among...
Mon Jul 06, 2020 03:00
IJERPH, Vol. 17, Pages 4874: Effects of DNA Damage and Oxidative Stress in Human Bronchial Epithelial Cells Exposed to PM2.5 from Beijing, China, in Winter International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17134874 Authors: Niu Li Li Hong Khodahemmati Gao Zhou Epidemiological studies have corroborated that respiratory diseases, including lung cancer, are related to fine particulate matter (<2.5 μm) (PM2.5) exposure....
Mon Jul 06, 2020 03:00
IJERPH, Vol. 17, Pages 4873: How Is the Presence of Company Related to Thwarted Belongingness in Real Time? Taking a Closer Look at the Conceptualization of the Construct of the Interpersonal Theory of Suicide International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17134873 Authors: Nina Hallensleben Heide Glaesmer Thomas Forkmann Dajana Rath Maria Strauss Anette Kersting Lena Spangenberg (1) Background: The role of thwarted belongingness...
Mon Jul 06, 2020 03:00
IJERPH, Vol. 17, Pages 4875: Emirati Women’s Knowledge about the Menopause and Menopausal Hormone Therapy International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17134875 Authors: Linda Smail Ghufran A. Jassim Khawla I. Sharaf The aim of this study was to investigate the knowledge of Emirati women aged 30–64 about menopause, menopausal hormone therapy (MHT), and their associated health risks, and additionally, to determine the relationships...
Mon Jul 06, 2020 03:00
IJERPH, Vol. 17, Pages 4871: Changes in the Type of Sports Activity Due to COVID-19: Hypochondriasis and the Intention of Continuous Participation in Sports International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17134871 Authors: Choi Bum This study focused on empirically analyzing sport activity participants’ perceptions of hypochondriasis caused by fear of infection and changes in continuous participatory behavior patterns. To this end,...
Mon Jul 06, 2020 03:00
IJERPH, Vol. 17, Pages 4868: Factors Influencing the Adoption of Shared Autonomous Vehicles International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17134868 Authors: Yuen Huyen Wang Qi Shared autonomous vehicles (SAVs), which have several potential benefits, are an emerging innovative technology in the market. However, the successful operation of SAVs largely depends on the extent of travellers’ intention to adopt them. This study aims...
Mon Jul 06, 2020 03:00
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