Abstract Pediatric sepsis has become the leading cause of death in pediatric intensive care units (PICU). The regulation of target genes may be the key to the treatment of pediatric sepsis. The expression of miR-210 in rat serum was detected by RT-qPCR. The serum BUN, Scr, and CysC were detected by an automatic biochemical analyzer. The expression of inflammatory factors was detected by ELISA. The apoptosis level of the cells was detected by TUNEL staining. The expression of apoptotic...
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Abstract Enteric glial cells (EGCs) and enteric glial–derived neurotrophic factor (GDNF) are directly involved in intestinal inflammation. In this study, we sought to examine the possible mechanisms for how Bifidobacterium bifidum (B.b.) and Bacteroides fragilis (B.f.) influence EGC regulation. In this study, lipopolysaccharide (LPS) and interferon-γ (IFN-γ) were used as exogenous stimuli of EGCs to establish an intestinal inflammation...
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Long-term outcomes of acute endovascular thrombectomy: Tokyo/tama-Registry of Acute Endovascular Thrombectomy (TREAT). World Neurosurg. 2020 Jul 01;: Authors: Ota T, Shigeta K, Inoue M, Matsumaru Y, Shiokawa Y, Hirano T Abstract BACKGROUND: Mechanical thrombectomy (MT) is the recommended treatment for patients with acute ischemic stroke (AIS) due to large cerebral vessel occlusion (LVO). However, very few studies have investigated long-term...
Mon Jul 06, 2020 14:53
Risk Factors of Cerebellar Microembolic Infarctions Following Carotid Artery Stenting. World Neurosurg. 2020 Jul 01;: Authors: Ito H, Uchida M, Kaji T, Go Y, Hidaka G, Takasuna H, Goto T, Takumi I, Tanaka Y Abstract This study analyzes the incidence of microembolic infarctions (MIs) in the cerebellum following carotid artery stenting (CAS) to determine the risk factors. From 2012 to 2019, 162 CASs in 155 patients were performed at our hospital....
Mon Jul 06, 2020 14:53
A rare case of pancreatoblastoma with intracranial seeding. World Neurosurg. 2020 Jul 01;: Authors: Snyder MH, Ampie L, Mandell JW, Helm GA, Syed HR Abstract BACKGROUND: Pancreatoblastoma is an extremely rare neoplasm that accounts for 0.5% of all pancreatic exocrine tumors. These rare entities typically manifest in the pediatric population but can rarely occur in adults. Systemic seeding has been described before but intracranial metastasis...
Mon Jul 06, 2020 14:53
Feasibility and Safety of Radial-First Approach With a Radial-Specific Neurointerventional Guiding Sheath for Intracranial Aneurysm Coiling in the Anterior Circulation. World Neurosurg. 2020 Jul 01;: Authors: Hanaoka Y, Koyama JI, Ogiwara T, Fujii Y, Ito K, Horiuchi T Abstract BACKGROUND: In cardiac intervention, the transradial approach (TRA) is increasingly used as the first-line approach owing to numerous advantages over the transfemoral...
Mon Jul 06, 2020 14:53
Publication date: Available online 5 July 2020Source: NeuroImageAuthor(s): Joanne C. Beer, Nicholas J. Tustison, Philip A. Cook, Christos Davatzikos, Yvette I. Sheline, Russell T. Shinohara, Kristin A. Linn, for the Alzheimer’s Disease Neuroimaging Initiative
Mon Jul 06, 2020 14:49
VAGUS NERVE STIMULATION IN EPILEPSY: EFFICIENCY AND SAFETY OF OUTPATIENT PRACTICE. Neurochirurgie. 2020 Jul 02;: Authors: Charles-Henry M, Irène O, Maria-Paola VH, Edouard H, François P, Dominique C Abstract INTRODUCTION: Over the past 20 years, Vagus Nerve Stimulation (VNS) has become one of the tools for surgical treatment of patients with refractory cryptogenic epilepsy. The objective of this study was to determine the feasibility of implanting...
Mon Jul 06, 2020 14:48
Long-Term Complications and Influence on Outcome in Patients Surviving Spontaneous Subarachnoid Hemorrhage. Cerebrovasc Dis. 2020 Jul 03;:1-9 Authors: Gerner ST, Reichl J, Custal C, Brandner S, Eyüpoglu IY, Lücking H, Hölter P, Kallmünzer B, Huttner HB Abstract BACKGROUND: While the short-term clinical outcome of patients with subarachnoid hemorrhage (SAH) is well described, there are limited data on long-term complications and their impact...
Mon Jul 06, 2020 14:25
EEG Source Imaging (ESI) utility in clinical practice. Biomed Tech (Berl). 2020 Jul 05;: Authors: Khosropanah P, Ho ET, Lim KS, Fong SL, Thuy Le MA, Narayanan V Abstract Epilepsy surgery is an important treatment modality for medically refractory focal epilepsy. The outcome of surgery usually depends on the localization accuracy of the epileptogenic zone (EZ) during pre-surgical evaluation. Good localization can be achieved with various electrophysiological...
Mon Jul 06, 2020 14:25
Cardiogenic cerebral infarction in the parietal lobe predicts the development of post-stroke epilepsy. Seizure. 2020 Jun 20;80:196-200 Authors: Takase KI Abstract PURPOSE: Post-stroke epilepsy (PSE) is a major late complication of cardioembolic cerebral infarction. However, few studies have examined the epileptogenicity and characteristics of first-occurrence cardioembolic cerebral infarctions. METHODS: This retrospective study included...
Mon Jul 06, 2020 14:25
A feasibility trial of an internet-delivered psychological intervention to manage mental health and functional outcomes in neurological disorders. J Psychosom Res. 2020 Jun 29;136:110173 Authors: Gandy M, Karin E, McDonald S, Meares S, Scott AJ, Titov N, Dear BF Abstract OBJECTIVE: Mental health and cognitive difficulties are highly prevalent across neurological disorders and significantly contribute to poorer patient outcomes. Unfortunately,...
Mon Jul 06, 2020 14:25
Effectiveness and tolerability of adjunctive brivaracetam in patients with focal seizures: Second interim analysis of 6-month data from a prospective observational study in Europe. Epilepsy Res. 2020 Apr 09;165:106329 Authors: Steinhoff BJ, Christensen J, Doherty CP, Majoie M, De Backer M, Hellot S, Leunikava I, Leach JP Abstract Brivaracetam (BRV) is indicated for adjunctive treatment of focal (partial-onset) seizures with or without secondary...
Mon Jul 06, 2020 14:25
Electro-clinical analysis of epilepsy patients with generalized seizures on adjunctive perampanel treatment. Epilepsy Res. 2020 May 31;165:106378 Authors: Montoya Gutiérrez FJ, Díaz Román M, Cerveró Albert D Abstract Quantifying epileptiform discharges before and after the initiation of treatment can be useful for evaluating the efficacy of antiepileptic drugs in generalized epilepsy. The aim of this study was to determine if the selective...
Mon Jul 06, 2020 14:25
Initiating a new national epilepsy surgery program: Experiences gathered in Georgia. Epilepsy Behav. 2020 Jul 01;111:107259 Authors: Dugladze T, Bäuerle P, Kasradze S, Lomidze G, Gzirishvili N, Tsikarishvili V, Khurtsidze G, Vida I, Schmitz D, Schneider UC, Holtkamp M, Gloveli T Abstract Surgery is the most effective therapeutic approach for medically refractory epilepsies and a safe and cost-efficient treatment in terms of long-term expenses...
Mon Jul 06, 2020 14:25
[Anxiety in neurological practice]. Zh Nevrol Psikhiatr Im S S Korsakova. 2020;120(5):165-170 Authors: Sivolap YP, Azimova YE Abstract Anxiety and related disorders are the most common type of mental disorders in both the general population and the neurological clinic. A current typology of anxiety disorders includes panic disorder, agoraphobia, simple (specific) phobias, social anxiety disorder, and generalized anxiety disorder. Anxiety disorders...
Mon Jul 06, 2020 14:25
[The problem of comorbidity of epilepsy and psychogenic paroxysms]. Zh Nevrol Psikhiatr Im S S Korsakova. 2020;120(5):138-145 Authors: Kutlubaev MA, Mendelevich VD, Dyukova GM, Belousova ED Abstract A review of publications over the last two decades is presented. Psychogenic paroxysms develop in approximately 12% of patients with epilepsy. The analysis of social and demographic data, history details, semiological features and results of electrophysiological...
Mon Jul 06, 2020 14:25
Neuromodulation for the Treatment of Epilepsy: a Review of Current Approaches and Future Directions.
Related Articles Neuromodulation for the Treatment of Epilepsy: a Review of Current Approaches and Future Directions. Clin Ther. 2020 Jun 30;: Authors: Davis P, Gaitanis J Abstract PURPOSE: Neuromodulation holds great promise for the treatment of drug-resistant epilepsy. This article reviews the most common types of neuromodulation as well as potential future applications of preclinical techniques such as optogenetics. This review serves as...
Mon Jul 06, 2020 14:25
Effects of viewing distance on ocular vestibular evoked myogenic potentials (oVEMPs) for air- and bone-conducted stimuli at multiple sites. J Vestib Res. 2020 Jun 27;: Authors: Govender S, Colebatch JG Abstract BACKGROUND: The ocular vestibular evoked myogenic potential is otolith-dependent and has been suggested to be a manifestation of the linear vestibulo-ocular reflex (L-VOR). A characteristic feature of the translational LVOR (t-LVOR)...
Mon Jul 06, 2020 14:22
Vestibular function analysis of sudden sensorineural hearing loss with dizziness. J Vestib Res. 2020 Jun 27;: Authors: Lee JY, Lee YW, Chang SO, Kim MB Abstract BACKGROUND: A considerable number of patients with sudden sensorineural hearing loss (SSNHL) have been reported to have dizziness. OBJECTIVE: To analyze vestibular functions and identify the clinical characteristics of SSNHL with dizzinessMETHODS:71 patients with SSNHL...
Mon Jul 06, 2020 14:22
Virtual and augmented reality for preoperative planning in plastic surgical procedures: A systematic review. J Plast Reconstr Aesthet Surg. 2020 May 26;: Authors: Vles MD, Terng NCO, Zijlstra K, Mureau MAM, Corten EML Abstract BACKGROUND: Virtual and augmented reality (VR and AR) are fast-developing technologies that allow the three-dimensional visualization of digital information. OBJECTIVE: This systematic review aimed to compare...
Mon Jul 06, 2020 14:08
Related Articles FFP3 reusable respirators for COVID-19; adequate and suitable in the healthcare setting. J Plast Reconstr Aesthet Surg. 2020 Jul;73(7):1357-1404 Authors: Higgins GC, Robertson E, Horsely C, McLean N, Douglas J PMID: 32620313 [PubMed - as supplied by publisher]
Mon Jul 06, 2020 14:08
Related Articles Cover Illustration: "Frontline" mural, Ashton Lane, Glasgow, by the.rebel.bearBack from the Frontline. J Plast Reconstr Aesthet Surg. 2020 Jul;73(7):1207 Authors: Hart PA PMID: 32620312 [PubMed - as supplied by publisher]
Mon Jul 06, 2020 14:08
Related Articles Letter comments on the Nerve decompression according to A.L. Dellon in Morton's neuroma - A retrospective analysis. J Plast Reconstr Aesthet Surg. 2020 Jun 12;: Authors: Cashley D PMID: 32620294 [PubMed - as supplied by publisher]
Mon Jul 06, 2020 14:08
Change of Pyogenic and Tuberculous Spondylitis between 2007 and 2016 Year : A Nationwide Study. J Korean Neurosurg Soc. 2020 Jul 06;: Authors: Kim YJ, Hong JB, Kim YS, Yi J, Choi JM, Sohn S Abstract Objective: We attempted to compare the incidence of pyogenic spondylitis (PS) and tuberculous spondylitis (TS) between 2007 and 2016. Furthermore, we investigated the patients who underwent surgery in 2016 compared to that in 2007. Methods:...
Mon Jul 06, 2020 13:58
Operative Safety of Curative Gastrectomy after Endoscopic Submucosal Dissection (ESD) for Early Gastric Cancer - 1:2 propensity score matching analysis: A retrospective single-center study (cohort study). Int J Surg. 2020 Jul 02;: Authors: Park KB, Jun CH, Seo HS, Jung YJ, Song KY, Park CH, Lee HH Abstract BACKGROUND: This study aimed to evaluate the operative safety and long-term outcomes of additional curative gastrectomy (ACG) after...
Mon Jul 06, 2020 13:52
Is prevention better than a cure? A letter to the editor on "World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19)". Int J Surg. 2020 Jul 02;: Authors: Sani I, Hamza Y, Amalendran J, Chedid Y, Ubaide H PMID: 32622935 [PubMed - as supplied by publisher]
Mon Jul 06, 2020 13:52
Optimal management of large proximal ureteral stones (>10mm): a systematic review and meta-analysis of 12 randomized controlled trials. Int J Surg. 2020 Jul 01;: Authors: Lai S, Jiao B, Diao T, Seery S, Hu M, Wang M, Hou H, Wang J, Zhang G, Liu M Abstract OBJECTIVES: To develop an evidence base to guide clinicians treating adults with large proximal ureteral stones (LPUS) greater than 10mm. METHODS: A systematic search of...
Mon Jul 06, 2020 13:52
SURGICAL PLANNING with PATIENT-SPECIFIC THREE-DIMENSIONAL PRINTED PANCREATICOBILIER DISEASE MODELS - Cross-Sectional Study. Int J Surg. 2020 Jul 01;: Authors: Bati AH, Guler E, Ozer MA, Govsa F, Erozkan K, Vatansever S, Ersin MS, Elmas ZN, Harman M Abstract BACKGROUND: Three-dimensional (3D) printing has been increasingly used in medical applications with the creation of accurate patient-specific 3D printed models in medical imaging data....
Mon Jul 06, 2020 13:52
An Invited Commentary on "No Alteration Of Cyp3a4 Activity After Major Hepatectomy In The Early Postoperative Period - A Prospective Before-After Study." Int J Surg. 2020 Jul 01;: Authors: Lin C, Xiao-Ping C PMID: 32622057 [PubMed - as supplied by publisher]
Mon Jul 06, 2020 13:52
Four interventions for pediatric femoral shaft fractures: network meta-analysis of randomized trials. Int J Surg. 2020 Jul 01;: Authors: Chen Z, Han D, Wang Q, Li L Abstract BACKGROUND: Fractures of the pediatric femoral shaft are uncommon,although serious injuries could lead to long-term disability, pain and an impaired quality of life. There are 4 main interventions: cast (C), plate fixation (PF), titanium elastic nail (TEN) and external...
Mon Jul 06, 2020 13:52
Overlapping Mechanisms of Exertional Heat Stroke and Malignant Hyperthermia: Evidence vs. Conjecture
Abstract Exertional heat stroke (EHS) and malignant hyperthermia (MH) are life-threatening conditions, triggered by different environmental stimuli that share several clinical symptoms and pathophysiological features. EHS manifests during physical activity normally, but not always, in hot and humid environments. MH manifests during exposure to haloalkane anesthetics or succinylcholine, which leads to a rapid, unregulated release of calcium (Ca2+) within the skeletal muscles inducing...
Mon Jul 06, 2020 03:00
A case of primary cutaneous B-cell lymphoma with immature features in an old man. Diffuse Large B-cell Lymhpoma with immature features or B-cell Lymhpoblastic Lymphoma? J Cutan Pathol. 2020 Jul 04;: Authors: Ronchi A, Zito Marino F, Vitiello P, Caccavale S, Argenziano G, Crisci S, Franco R, Sica A Abstract Primary cutaneous B-cell lymphomas are a heterogeneous group of lymphoid neoplasms primarily occurring in the skin. Although most cases...
Mon Jul 06, 2020 13:48
Rare case of pregnancy with vaginal adenocarcinoma. Int J Surg Case Rep. 2020 Jun 11;: Authors: Xu Y, Li C, Wei B, Wang W Abstract INTRODUCTION: Primary vaginal cancer accounts for only 3% of female reproductive tract malignant tumours, and 5% of primary vaginal cancers are adenocarcinomas. Reports of pregnancy with vaginal adenocarcinoma are very rare. There is no guidance for its diagnosis and treatment. CASE PRESENTATION: A 27-year-old...
Mon Jul 06, 2020 13:48
Mohs micrographic surgery: a treatment method for many non-melanocytic skin cancers. Dermatol Online J. 2020 Apr 15;26(4): Authors: Dokic Y, Nguyen QL, Orengo I Abstract Mohs micrographic surgery (MMS) is a breakthrough surgical technique that has changed the management of neoplasms in dermatology. Through continued practice and evolution, MMS now can successfully treat a variety of rare non-melanocytic cutaneous malignancies for which achieving...
Mon Jul 06, 2020 13:48
Related Articles Submucosal gland neoplasms of the esophagus: an update and review. Esophagus. 2020 Jul 03;: Authors: Nie L, Li W, Xue L, Wang L, Shen Y, Fan X Abstract Submucosal glands (SMGs) present throughout human esophagus with clusters at either the upper third or lower third of the organ. SMGs tend to atrophy with age, and neoplasms arising in these glands are rare. In order to bring convenience to diagnosis, we summarize the histopathologic...
Mon Jul 06, 2020 13:48
Related Articles Lymphoma Predisposing Gene in an Extended Family: CD70 Signaling Defect. J Clin Immunol. 2020 Jul 03;: Authors: Khodzhaev K, Bay SB, Kebudi R, Altindirek D, Kaya A, Erbilgin Y, Ng OH, Kiykim A, Erol FC, Zengin FS, Firtina S, Ng YY, Aksoy BA, Sayitoglu M Abstract Genome-wide sequencing studies in pediatric cancer cohorts indicate that about 10% of patients have germline mutations within cancer predisposition genes. Within this...
Mon Jul 06, 2020 13:48
Related Articles [Systemic treatment of locally advanced or metastatic penile cancer]. Bull Cancer. 2020 Jun;107(5S):S17-S23 Authors: Gassian N, Frontczak A, El Kaddissi A, Calcagno F, Almotlak H, Barkatz J, Mouillet G, Maurina T, Stein U, Nguyen Tan Hon T, Murez T, Thiery-Vuillemin A Abstract Penile cancers are rare, the vast majority is represented by squamous cell carcinoma, with HPV virus being found in 30 to 40% of cases. At a locally advanced...
Mon Jul 06, 2020 13:48
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